Mea Kākau: Marcus Baldwin
Lā O Ka Hana: 21 Iune 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Teriflunomide To Treat Relapsing Forms of Multiple Sclerosis - Overview
Wikiō: Teriflunomide To Treat Relapsing Forms of Multiple Sclerosis - Overview

Anter

ʻO Teriflunomide paha ke kumu o ka hōʻeha o ke ake a weliweli paha i ke ola, e koi paha i kahi neʻe ʻana o ke ake. Hiki ke hoʻonui ʻia ka makaʻu o ka hōʻino ʻana o ke akepaʻa i ka poʻe e lawe ana i nā lāʻau ʻē aʻe i ʻike ʻia e hōʻino ai i ke ake, a i ka poʻe i loaʻa i ka maʻi ate. E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi ate. E haʻi paha kāu kauka iā ʻoe mai lawe i teriflunomide. E haʻi i kāu kauka a me kāu kauka lāʻau e pili ana i nā lāʻau a pau āu e lawe nei i hiki iā lākou ke nānā inā paha e hoʻonui paha kekahi o kāu mau lāʻau i ka makaʻi e hoʻomohala ʻoe i ka hōʻino o ke ake i kāu mālama ʻana me teriflunomide. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: nausea, luaʻi, luhi nui loa, kahe ʻana o ke kōkō a ʻeha paha, ka nele o ka ikaika, nalo ʻole o ka makemake, ʻeha ma ka ʻaoʻao ʻākau i luna o ka ʻōpū, melemele o ka ʻili a me nā maka. , mimi ʻeleʻele, a i ʻole nā ​​hōʻailona like flu. Inā kuhi ʻia ka hōʻino o ke ake, hiki i kāu kauka ke kāpae i ka teriflunomide a hāʻawi iā ʻoe i kahi lāʻau e kōkua ai e hemo wikiwiki i ka teriflunomide mai kou kino.


E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau a maʻa mau i kou wā e mālama ai e nānā i ka pane o kou kino i teriflunomide.

Mai lawe i ka teriflunomide inā hāpai ʻoe a hoʻolālā paha e hāpai. Hoʻopilikia paha ʻo Teriflunomide i ka fetus. ʻAʻole pono ʻoe e hoʻomaka i ka lawe ʻana i ka teriflunomide a hiki i kou hōʻoia ʻana i ka hāpai ʻana me nā hopena maikaʻi ʻole a haʻi aku kāu kauka iā ʻoe ʻaʻole ʻoe hāpai. Pono ʻoe e hoʻohana i kahi hana kūpono o ka kaohi hānau ma mua o kou hoʻomaka ʻana i ka teriflunomide, i kou wā e mālama ʻia ai me teriflunomide, a hiki i 2 mau makahiki ma hope o ka hoʻomaʻamaʻa ʻana, a hiki i ka hōʻike ʻana o nā hōʻike koko ke loaʻa iā ʻoe nā pae haʻahaʻa o ka teriflunomide i loko o kou koko. Inā lohi kou manawa, haʻo ʻoe i kahi manawa, a manaʻo paha ʻoe e hāpai ana ʻoe i kāu wā e mālama ai me teriflunomide a i ʻole 2 mau makahiki ma hope o kāu lapaʻau ʻana, e kāhea koke i kāu kauka. Inā he kāne ʻoe a hiki i kāu pakanā ke hāpai, pono ʻoe a me kāu hoa e hoʻohana pono i ka kaohi hānau i kāu wā lapaʻau. Inā ʻoe a i ʻole kāu pakanā e hoʻolālā e hāpai a i ʻole hiki ke hāpai, e kamaʻilio me kāu kauka e pili ana i kahi lapaʻau e kōkua ai e hemo wikiwiki i ka teriflunomide mai kou kino ma hope o kou hōʻoki ʻana i ka lawe ʻana i ka lāʻau.


E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka ʻikepili ʻike hoʻomanawanui o ka mea hana (Ke alakaʻi lāʻau) ke hoʻomaka ʻoe i ka lāʻau me teriflunomide a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i nā makaʻu o ka lawe ʻana i teriflunomide.

Hoʻohana ʻia ʻo Teriflunomide e mālama i nā mākua me nā ʻano like ʻole o ka sclerosis maha (MS; kahi maʻi kahi e holo pono ʻole ai nā ʻalolo a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka hoʻohuihui ʻana o nā mākala, a me nā pilikia me ka hihiʻo, ka ʻōlelo, a me ka mālama ʻana i ka maʻi ʻaʻa) me :

  • maʻi hoʻokaʻawale clinically (CIS; nā ʻōuli ʻōuli nerve e kū ma ka liʻiliʻi he 24 mau hola),
  • relapsing-remitting forms (papa o ka maʻi kahi e ʻō ai nā ʻōuli mai kēlā me kēia manawa), a i ʻole
  • nā papa holomua holomua (papa o ka maʻi kahi e hoʻi pinepine ai ka hoʻi ʻana).

Aia ʻo Teriflunomide i loko o ka papa o nā lāʻau i kapa ʻia he mau mea pale maʻi. Manaʻo ʻia e hana ma ka hōʻemi ʻana i ka mumū a me ka hōʻemi ʻana i ka hana o nā hunaola ʻino e hiki ai ke hōʻino i nā nerve.


Hele mai ʻo Teriflunomide ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka ʻai ʻole. Lawe i ka teriflunomide ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka teriflunomide. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hiki paha i Teriflunomide ke kōkua i ka mālama ʻana i nā ʻōuli o nā sclerosis he nui, akā ʻaʻole ia e hoʻōla iā ia. E hoʻomau i ka lawe ʻana i teriflunomide ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i teriflunomide me ka walaʻau ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i teriflunomide,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka teriflunomide (hū, hives, ka pōkole o ka hanu, pehu o ka maka, maka, waha, ʻāʻī, alelo, lehelehe, lima, wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo), leflunomide (Arava) , kekahi mau lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i nā papa teriflunomide. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • E haʻi i kāu kauka inā lawe ʻoe i ka leflunomide (Arava). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka teriflunomide inā ʻoe e lawe i kēia lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i nā lāʻau i helu ʻia i ka ʻĀINA Aʻoaʻo koʻikoʻi a me kekahi o nā mea aʻe: alosetron (Lotronex); anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven); atorvastatin (Lipitor, ma Caduet); cefaclor; cimetidine (Tagamet); ciprofloxacin (Cipro); duloxetine (Cymbalta); eltrombopag (Promacta); furosemide (Lasix); gefitinib (Iressa); ketoprofen; nā lāʻau e hiki ai ke hōʻeha i nā nerve e like me nā lāʻau no ka maʻi ʻaʻai, HIV, a i ʻole AIDS; nā lāʻau lapaʻau e kāohi i ka ʻōnaehana pale e like me azathioprine (Azasan, Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), a me tacrolimus (Astagraf, Envarsus XR, Prograf); methotrexate (Otrexup, Rasuvo, Trexall); mitoxantrone; nateglinide (Starlix); nā pale pale waha (nā pā kaohi hānau); paclitaxel (Abraxane, Taxol); penikila G; pioglitazone (Actos, i Actoplus Met, i Duetact); pravastatin (Pravachol); repaglinide (Prandin, ma Prandimet); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); rosiglitazone (Avandia); rosuvastatin (Crestor); simvastatin (Zocor, i Vytorin); theophylline (Elixophyllin, Theo-24, Uniphyl, kekahi); tizanidine (Zanaflex); a me zidovudine (Retrovir, ma Combivir, ma Trizivir). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me teriflunomide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa ʻoe i kahi maʻi i kēia manawa, me kahi maʻi hoʻomau e hele ʻole ana, a inā ua loaʻa a loaʻa paha iā ʻoe kahi hopena maikaʻi o ka ʻili ma hope o kou lawe ʻana i kahi lāʻau ʻē aʻe. mimikō; nā pilikia hanu; ka maʻi ʻaʻai a i ʻole nā ​​kūlana ʻē aʻe e pili ana i ka momona o ka iwi a i ʻole ka pale pale ke koko kiʻekiʻe; peripheral neuropathy (numbness, puhi ʻana a i ʻole ke kani ʻana i nā lima a me nā wāwae e ʻokoʻa ana i kāu MS hōʻailona); a maʻi maʻi ʻōpae paha.
  • e haʻi i kāu kauka inā ʻoe e hānai umauma ana. Mai hānai i ka wā e lawe ana i teriflunomide.
  • inā hoʻolālā kāu hoa e hāpai, pono ʻoe e kamaʻilio me kāu kauka e pili ana i ka hoʻōki ʻana i ka teriflunomide a me ka loaʻa ʻana i kahi lāʻau e kōkua i ka lawe koke ʻana i kēia lāʻau mai kou kino aku. Inā ʻaʻole hoʻolālā kāu pakanā e hāpai, pono ʻoe a me kāu pakanā e hoʻohana i kahi hana kūpono o ka kaohi hānau i ka wā o kāu mālama ʻana me teriflunomide a hiki i 2 mau makahiki ma hope o ka hoʻomaʻamaʻa ʻana, a hiki i ka hōʻike ʻana o nā hōʻike koko ke loaʻa iā ʻoe nā pae haʻahaʻa he nui o ka teriflunomide i kāu. koko.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i teriflunomide.
  • ua hele a maʻi paha ʻoe me ka maʻi puʻupuʻu (TB; kahi maʻi puʻuwai koʻikoʻi) akā ʻaʻole i loaʻa nā ʻōuli o ka maʻi. E haʻi i kāu kauka inā loaʻa paha iā ʻoe ka TB, inā ua noho ʻoe a kipa paha i kahi ʻāina e maʻa mau ai ka TB, a i ʻole inā ua puni ʻoe i kekahi i loaʻa iā TB paha. Ma mua o kou hoʻomaka ʻana i kāu lapaʻau me teriflunomide, e hana ana kāu kauka i kahi hoʻokolohua ʻili e ʻike inā he TB kāu. Inā loaʻa iā ʻoe ka TB, e mālama kāu kauka i kēia maʻi ma mua o kou hoʻomaka ʻana e lawe i ka teriflunomide.
  • ʻaʻohe o nā lāʻau āpau me ke kamaʻilio ʻole ʻana me kāu kauka ke lawe nei ʻoe i teriflunomide a no 6 mau mahina ma hope o kou hoʻōki ʻana i kāu lawe ʻana.
  • pono ʻoe e ʻike i ka teriflunomide i kumu ke kiʻekiʻe o ke koko. Pono ʻoe e nānā i kou kaomi koko ma mua o ka hoʻomaka ʻana i ka lāʻau a me ka manawa mau iā ʻoe e lawe nei i kēia lāʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Teriflunomide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • poho lauoho
  • pāhoehoe
  • ʻike hihi
  • ʻeha ʻeha
  • huehue
  • ʻeha hui a ʻeha ʻeha paha
  • hopohopo
  • Kaumaha emi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e hoʻōki i ka lawe ʻana i teriflunomide a kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

  • wikiwiki, kūlike ʻole, a i ʻole kuʻi puʻuwai
  • ʻeha poʻo
  • ʻūpā
  • ʻili mae
  • huikau
  • fiva, uha, ʻāʻī ʻeha, haʻalulu, a me nā ʻōuli ʻē aʻe o ka maʻi
  • numbness, puhi ʻana, a i ʻole ke kani ʻana i nā lima, nā lima, nā wāwae, a me nā wāwae
  • nalo o ke kani nāʻiʻo
  • nāwaliwali a kaumaha paha i nā wāwae
  • anuanu, ʻili hina
  • ʻulaʻula, ʻiliʻili ʻana, a i ʻole ʻili ʻōwili
  • hūwī
  • hives
  • ʻūlili
  • paʻakikī i ka ale ʻana
  • pehu o ka maka, maka, waha, ʻāʻī, elelo, a me nā lehelehe
  • pokole o ka hanu
  • hū e hiki ke kū mai me ke kuni, nā pehu pehu, a me ka pehu o ka maka
  • ʻeha, ʻaoʻao, a ʻeha hoʻi

Hoʻokumu paha ʻo Teriflunomide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 01/15/2021

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