Mea Kākau: Clyde Lopez
Lā O Ka Hana: 22 Iulai 2021
HōʻAno Hou I Ka Lā: 14 Nowemapa 2024
Anonim
Andreas Hochhaus: Asciminib vs. Bosutinib in Chronic Myeloid Leukemia
Wikiō: Andreas Hochhaus: Asciminib vs. Bosutinib in Chronic Myeloid Leukemia

Anter

Hoʻohana ʻia ʻo Bosutinib e mālama i kekahi ʻano o ka leukemia myeloid maʻi mau (CML; kahi ʻano maʻi ʻaʻai o nā hunaola keʻokeʻo), e like me ka mālama ʻana i ka poʻe i loaʻa hou i kēia ʻano a me nā mea hiki ʻole ke kōkua hou ʻia mai nā lāʻau ʻē aʻe. no CML a i ʻole hiki ʻole ke lawe i kēia mau lāʻau no ka hopena o ka hopena. Aia ʻo Bosutinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Bosutinib ma ke ʻano he papa e lawe ma ka waha. Lawe mau ʻia me ka meaʻai hoʻokahi i ka lā. Lawe iā bosutinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe iā bosutinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou. Inā haki a hū paha kekahi o nā papa, mai hoʻopā aku iā lākou me kou mau lima.


Kāohi paha kāu kauka i kahi manawa a kūloko paha i kāu lāʻau lapaʻau a hoʻoponopono paha i kāu lāʻau o bosutinib ma muli o kāu pane i ka lāʻau a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana iā bosutinib inā ʻoe e ʻoluʻolu. Mai hōʻoki i ka lawe ʻana iā bosutinib me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i bosutinib,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka bosutinib a i ʻole kekahi o nā mea hana i nā papa bosutinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: kekahi antifungals e like me ketoconazole a me itraconazole (Sporanox); aprepitant (Emend); kekahi mau lāʻau i hoʻohana ʻia e mālama ai i ka maʻi pale maʻi kanaka (HIV) e like me indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), a me saquinavir (Invirase); nā lāʻau e hoʻoliʻiliʻi i ka acid acid (proton-pump inhibitors) e like me esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), a me rabeprazole (AcipHex); diltiazem (Cardizem, Cartia, Tiazac); erythromycin (E.E.S., E-Mycin, Erythrocin); nefazodone; rifabutin (Mycobutin); a me rifampin (Rifadin, Rimactane ma Rifamate, ma Rifater). Nui paha nā lāʻau ʻē aʻe e launa pū paha me bosutinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • inā ʻoe e lawe i nā antacids, e like me ka aluminium hydroxide / magnesium hydroxide (Maalox), calcium carbonate (Tums) a i ʻole calcium carbonate a me ka magnesium (Rolaids) a i ʻole nā ​​lāʻau e hōʻemi ai i ka waikawa ʻōpū, e like me cimetidine (Tagamet), famotidine (Pepcid), a i ʻole ranitidine (Zantac), lawe iā lākou i 2 mau hola ma mua a i ʻole 2 mau hola ma hope o kou lawe ʻana i bosutinib.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe ka hakuʻala, ka ake, a i ʻole ka maʻi puʻuwai.
  • e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau lapaʻau a ʻaʻole ʻoe e hāpai ʻoiai ʻoe e lawe nei iā bosutinib. Pono ʻoe e hoʻohana i kahi ʻano kūpono o ka kaohi hānau ma ka mālama ʻana me bosutinib a no 2 mau pule ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana iā bosutinib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Bosutinib i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i bosutinib a no 2 mau pule ma hope o kāu hopena hope loa.
  • pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i bosutinib.

Mai ʻai i ka huaʻulu, inu i ka wai wai, a i ʻole lawe i nā waihona i loko o ka huaʻulu grapefruit i ka lawe ʻana i kēia lāʻau.


E lawe i ka lāʻau i hala me ka ʻai ke hoʻomanaʻo ʻoe iā ia.Eia nō naʻe, inā ʻoi aku ma mua o 12 mau hola mai kou hopena hope loa, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Bosutinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻeha poʻo
  • nalo ʻai ʻole
  • nāwaliwali a nāwaliwali paha
  • hoʻololi i ka hiki ke ʻono i ka meaʻai
  • kani i nā pepeiao

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • nausea
  • ka luaʻi
  • pāhoehoe
  • ʻeha ʻeha o ka ʻōpū
  • kahe koko ʻole ʻia a palapū paha
  • ke koko i ka mimi a i ʻole ka noho
  • hoʻololi i ke alapine o ka urination
  • hoʻonui a hoʻēmi paha i ka nui o ka mimi
  • ʻūpā
  • fiva, ʻeha ka ʻāʻī, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
  • pōkole o ka hanu a me ka puʻe
  • ʻeha ka umauma
  • ka pehu o ka maka, ka lima, nā kuʻekuʻe wāwae, nā wāwae, a me nā wāwae lalo
  • loaʻa kaumaha kaumaha
  • melemele o ka ʻili a me nā maka
  • mimi ʻeleʻele a i ʻole kī kī
  • hives
  • hūwī
  • ʻūlili
  • pilikia i ka hanu ʻana a i ʻole ke ale ʻana

Hoʻokumu paha ʻo Bosutinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā bosutinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Bosulif®
Nānā Hou - 12/15/2019

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