Brentuximab Vedotin Hoʻokomo

Anter

• Hoʻohana ʻia ʻo Brentuximab vedotin injection
• Ma mua o ka loaʻa ʻana o ka injection brentuximab vedotin,
• Hoʻokumu paha ʻo Brentuximab vedotin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

ʻO ka loaʻa ʻana o ka injection brentuximab vedotin hiki ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i ka leukoencephalopathy multifocal holomua (PML; kahi maʻi laha ʻole o ka lolo i hiki ʻole ke mālama ʻia, pale ʻia, a hoʻōla ʻia a ʻo ia hoʻi ka mea e make ai a kīnā nui ʻia). E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi ʻano e hoʻopili i kāu ʻōnaehana pale maʻi. E haʻi i kāu kauka a me ka kauka inā ʻoe e lawe i nā lāʻau e kāohi i ka ʻōnaehana pale. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hoʻōki i ka loaʻa ʻana o ka injection brentuximab vedotin a kāhea koke i kāu kauka: ua hoʻemi i ka ikaika a i ʻole nāwaliwali ma kekahi ʻaoʻao o ke kino; paʻakikī i ka hele wāwae; nalowale o ka hoʻohui ʻana; ʻeha poʻo; huikau; paʻakikī e noʻonoʻo pono; nalo hoʻomanaʻo; nā hoʻololi i ka naʻau a i ʻole ka hana maʻamau; paʻakikī e ʻōlelo; a i ʻole hoʻololi i ka hihiʻo.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Hiki paha i kāu kauka ke kauoha i kekahi mau hoʻokolohua e nānā i ka pane o kou kino i ka inikua brentuximab vedotin.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka loaʻa ʻana o ka injection brentuximab vedotin.

Hoʻohana ʻia ʻo Brentuximab vedotin injection

• i ka hui pū me nā lāʻau chemotherapy e mālama ai i ka lymphoma o Hodgkin (ka maʻi ʻo Hodgkin) i ka poʻe i loaʻa ʻole ka lāʻau ma mua.
• e mālama i ka lymphoma o Hodgkin i ka poʻe i makaʻu i ko lākou maʻi e ʻoi aku ka maikaʻi a hoʻi mai paha ma hope o kahi transplant cell stem (ke kaʻina e hoʻololi i ka iwi iwi maʻi me ka momona iwi maikaʻi),
• e mālama i ka lymphoma o Hodgkin i ka poʻe i pane ʻole i ka transplant cell stem (ke kaʻina e hoʻololi i ka iwi iwi maʻi me ka iwi iwi maikaʻi) a i ʻole ʻelua mau manawa lapaʻau o ka chemotherapy,
• i ka hui pū me nā lāʻau chemotherapy e mālama i ka lymphoma nui anaplastic (sALCL; kahi ʻano o ka lymphoma non-Hodgkin) a me kekahi ʻano ʻē aʻe o nā lymphomas T-cell peripheral (PTCL; kahi ʻano lymphoma non-Hodgkin) i ka poʻe i loaʻa ʻole ma mua loaʻa lapaʻau,
• e mālama i ka sALCL ʻōnaehana i loko o ka poʻe i pane ʻole i kahi wā mālama ʻē aʻe o ka chemotherapy,,
• e mālama i kekahi ʻano o ka cutaneus capereus anaplastic cell cell lymphoma nui (pcALCL; kahi ʻano o ka lymphoma non-Hodgkin) i ka poʻe i loaʻa i ka lāʻau hou.

ʻO ka inikū Brentuximab vedotin i loko o ka papa o nā lāʻau i kapa ʻia he conjugates antibody-drug. Hana ia ma ka luku ʻana i nā hunaola maʻi ʻaʻai.

ʻO ka injection Brentuximab vedotin e hele mai me he lepo lā e hui ʻia me ka wai a injected ma luna o 30 mau minuke i loko o ke aniani (i loko o kahi aa) e ke kauka a kahu wahine paha i kahi keʻena olakino a haukapila paha. Ke hāʻawi ʻia ka brentuximab vedotin e mālama i ka lymphoma o Hodgkin, sALCL, a i ʻole PTCL, ʻoki pinepine ʻia i hoʻokahi manawa i kēlā me kēia 3 mau pule no ka mea ke paipai ke kauka e loaʻa iā ʻoe ka lāʻau. Ke hoʻohana ʻia ka brentuximab vedotin me ka chemotherapy e mālama iā Hodgkin lymphoma ma ke ʻano he lapaʻau mua, ua injected ʻia hoʻokahi manawa i kēlā me kēia 2 mau pule no ka mea ke koi aku kāu kauka e loaʻa iā ʻoe ka lāʻau.

Hiki i ka inikua Brentuximab vedotin ke kumu i nā hopena maʻi kūpilikiʻi, i hana mau ʻia i ka wā o ka hoʻokomo ʻana o ka lāʻau a i ʻole ma loko o 24 mau hola o ka loaʻa ʻana o kahi lāʻau. Hiki iā ʻoe ke loaʻa i kekahi mau lāʻau i mua o kou hoʻopili ʻana e pale i kahi hopena maʻi inā loaʻa ʻoe i kahi hopena me nā lāʻau ma mua. E nānā pono kāu kauka iā ʻoe ke loaʻa iā ʻoe ka brentuximab vedotin. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: ke kuni, ke anuanu, ka hū, ka hives, ka ʻū, a me ka paʻakikī e hanu.

Pono paha kāu kauka e hoʻolohi i kāu lāʻau, hoʻoponopono i kāu lāʻau, a i ʻole hoʻokū i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E hoʻomaopopo pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me ka inikōleo brentuximab vedotin.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection brentuximab vedotin,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka brentuximab vedotin, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea i loaʻa i ka brentuximab vedotin injection. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• E haʻi i kāu kauka inā loaʻa iā ʻoe ka bleomycin. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hoʻohana i ka injection brentuximab vedotin inā e loaʻa ana iā ʻoe kēia lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: clarithromycin (Biaxin, ma PrevPac), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole, nefazodone, nelfinavir (Viracept), rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater), ritonavir (Norvir, ma Kaletra). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate a me nā puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau a hoʻohana i ka kaohi hānau hānau maikaʻi i kāu wā e mālama ai a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe me kāu hoa wahine hāpai a hāpai paha, pono ʻoe e hoʻohana i ka kaohi hānau pono i kāu wā e mālama ai a no 6 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana. Inā hāpai ʻoe a ʻo kāu hoa paha i ka loaʻa ʻana o ka injection brentuximab vedotin, e kelepona koke i kāu kauka. Hiki i ka brentuximab vedotin injection ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e loaʻa ana iā ʻoe ka brentuximab vedotin injection.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka loaʻa ʻana o ka injection brentuximab vedotin.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokumu paha ʻo Brentuximab vedotin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kōpaʻa
• ʻeha nā waha
• hoʻēmi ʻai
• Kaumaha emi
• luhi
• ʻūpā
• nāwaliwali
• paʻakikī e hiamoe a hiamoe paha
• hopohopo
• ʻili maloʻo
• poho lauoho
• puhū pō
• ʻeha, iwi, nāʻiʻo, hoʻi, lima, a ʻeha ʻeha paha
• ʻūpē mākala

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• kahe koko ʻole ʻana a palapū paha
• numbness, puhi ʻana, a i ʻole ke kani ʻana i nā lima, nā lima, nā wāwae, a me nā wāwae
• nāwaliwali o nā mākala
• ʻili a ʻili paha i ka ʻili
• hives
• hūwī
• ʻūlili
• nausea
• ka luaʻi
• pāhoehoe
• uha a me ka pōkole o ka hanu
• hoʻemi urination
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• paʻakikī, ʻeha, a i ʻole ka urino pinepine
• ke kuni, ke anu, ka ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ʻeha mau e hoʻomaka i ka wahi o ka ʻōpū akā e pālahalaha paha i ka hope
• ʻili mae
• melemele o ka ʻili a me nā maka
• ʻeha a hōʻoluʻolu ʻole paha ma ka ʻaoʻao ʻōpū o luna pono
• mimi ʻeleʻele
• neʻe ʻana o ka ʻōpū o ka ʻōpala
• ʻeha ka ʻōpū
• kahe koko ʻole ʻana a palapū paha
• pahu noho ʻeleʻele a lohi hoʻi
• koko ʻulaʻula i nā noho

Hoʻokumu paha ka injection Brentuximab vedotin i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ke kuni, ke anu, ka ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka injection brentuximab vedotin.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Adcetris^®