Mea Kākau: Janice Evans
Lā O Ka Hana: 28 Iulai 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Lurasidone Review - Mechanism of Action, Side Effects and Clinical Pearls
Wikiō: Lurasidone Review - Mechanism of Action, Side Effects and Clinical Pearls

Anter

ʻO ka ʻōlelo aʻoaʻo nui no nā mākua makua me ka dementia:

Ua hōʻike ʻia nā noiʻi i nā mākua makua me ka dementia (kahi maʻi lolo e pili ana i ka hiki ke hoʻomanaʻo, noʻonoʻo pono, kamaʻilio, a hana i nā hana o kēlā me kēia lā a hiki i nā mea e hoʻololi i ka naʻau a me ke ʻano) e lawe i nā antipsychotics (nā lāʻau no ka maʻi noʻonoʻo) e like me lurasidone loaʻa ka manawa kūpono o ka make i ka wā o ka lāʻau. Loaʻa paha i nā mākua me ka dementia ka manawa kūpono e loaʻa i ka hahau a i ʻole ka ministroke i ka wā o ka mālama ʻana me nā antipsychotics.

ʻAʻole ʻae ʻia ʻo Lurasidone e ka Food and Drug Administration (FDA) no ka hoʻomaʻamaʻa ʻana i nā maʻi o ka lawena i nā mākua me ka dementia. E kamaʻilio me ke kauka nāna i kuhikuhi i kēia lāʻau inā ʻoe, he lālā o ka ʻohana, a i ʻole kekahi mea āu e mālama ai he dementia a ke lawe nei i ka lurasidone. No ka ʻike hou aku e kipa i ka pūnaewele FDA: http://www.fda.gov/Drugs

Ka ʻōlelo aʻoaʻo nui no ka poʻe i loaʻa ke kaumaha:

ʻO kahi liʻiliʻi o nā keiki, ʻōpio, a me nā ʻōpio ʻōpio (a hiki i ka 24 mau makahiki) i lawe i nā lāʻau no ke kaumaha i ka wā o ka noiʻi maʻi ʻana i lilo i suicidal (e noʻonoʻo ana e hōʻeha a pepehi paha iā ʻoe iho a i ʻole ke hoʻolālā ʻana a hoʻāʻo paha e hana pēlā). ʻO nā keiki, ʻōpio, a me nā ʻōpio ʻōpio e lawe i nā antidepressants e mālama i ke kaumaha a i ʻole nā ​​maʻi noʻonoʻo ʻē aʻe e lilo i suicidal ma mua o nā keiki, ʻōpio, a me nā ʻōpio makua ʻole i lawe ʻole i nā antidepressants e mālama i kēia mau ʻano. Eia naʻe, ʻaʻole maopopo ka poʻe loea e pili ana i ka nui o kēia pilikia a pehea e noʻonoʻo ai i ka hoʻoholo ʻana inā paha e lawe kahi keiki a mea ʻōpio paha i kahi antidepressant. ʻAʻole pono nā kamaliʻi ma mua o 10 mau makahiki e lawe i ka lurasidone e mālama ai i ke kaumaha, akā i kekahi mau hihia, hiki i ke kauka ke hoʻoholo ʻo lurasidone ka lāʻau lapaʻau maikaʻi loa e mālama ai i ke ʻano o ke keiki.


Pono ʻoe e ʻike e loli paha kou olakino noʻonoʻo i nā ala i manaʻo ʻole ʻia ke lawe ʻoe i ka lurasidone e mālama ai i ke kaumaha a i ʻole nā ​​maʻi noʻonoʻo ʻē aʻe inā he mākua ʻoe ma mua o 24 mau makahiki. E lilo paha ʻoe i suicidal, keu hoʻi i ka hoʻomaka o kāu lapaʻau a i kēlā me kēia manawa e hoʻonui a hoʻemi ʻia paha kāu lāʻau. ʻO ʻoe, kou ʻohana, a i ʻole kāu mea mālama e kāhea koke aku i kāu kauka inā ʻike ʻoe i kekahi o kēia mau ʻōuli: ke kaumaha hou a i ʻole ke kaumaha paha; ke noʻonoʻo nei e pili ana i ka hōʻino a pepehi paha iā ʻoe iho, a i ʻole ke hoʻolālā ʻana a hoʻāʻo ʻana paha e hana pēlā; hopohopo nui loa; hoʻonāukiuki; hoʻouka weliweli; paʻakikī e hiamoe a hiamoe paha; hana kolohe; ukiuki; hana me ka noʻonoʻo ʻole; hoʻomaha ʻole loa; a me ka pīhoihoi pīhoihoi frenzied. E ʻike pono i kou ʻohana a mea mālama paha e ʻike i nā hōʻailona e koʻikoʻi paha i hiki iā lākou ke kāhea i ke kauka inā ʻaʻole hiki iā ʻoe ke ʻimi iā ʻoe lāʻau ponoʻī.

Makemake kāu mea mālama ola e ʻike pinepine iā ʻoe ke lawe nei ʻoe i ka lurasidone, keu hoʻi i ka hoʻomaka o kāu lapaʻau. E mālama pono i nā koho a pau no ke kipa keʻena me kāu kauka.


He mea ʻole i kou mau makahiki, ma mua o kou lawe ʻana i kahi antidepressant, pono ʻoe, kou ʻohana, a i ʻole kāu mea mālama e kamaʻilio me kāu kauka e pili ana i nā pilikia a me nā pono o ka mālama ʻana i kāu kūlana me ka antidepressant a i ʻole me nā lāʻau ʻē aʻe. E kamaʻilio pū ʻoe e pili ana i nā makaʻi a me nā pōmaikaʻi o ka mālama ʻole ʻana i kou ʻano. Pono ʻoe e ʻike i ka loaʻa ʻana o ke kaumaha a i ʻole kekahi maʻi noʻonoʻo e hoʻonui nui ai i ka makaʻu e lilo ʻoe i suicidal. ʻOi aku ka kiʻekiʻe o kēia makaʻāinana inā ʻo ʻoe a i ʻole kekahi o kou ʻohana i loaʻa a i ʻole loaʻa paha i kahi maʻi bipolar (ʻano e loli ai mai ke kaumaha i ka pīhoihoi ʻole) a i ʻole mania a i manaʻo ʻia a i ʻole i hoʻāʻo i ka pepehi kanaka. E kamaʻilio me kāu kauka e pili ana i kou ʻano, nā ʻōuli, a me ka mōʻaukala pilikino a me ka ʻohana. E hoʻoholo ʻoe a me kāu kauka i ke ʻano o ke kūpono kūpono iā ʻoe.

Hoʻohana ʻia ʻo Lurasidone e mālama i nā ʻōuli o schizophrenia (kahi maʻi noʻonoʻo e hoʻohaunaele ai ʻole noʻonoʻo ʻole, nalowale o ka hoihoi i ke ola, a me nā manaʻo ikaika a kūpono ʻole paha) i nā mākua a me nā keiki ʻo 13 mau makahiki a ʻoi paha. Hoʻohana ʻia ia e mālama i ke kaumaha i nā mākua a me nā keiki he 10 mau makahiki a ʻoi aku me ka maʻi bipolar (manic depressive maʻi; kahi maʻi e hoʻoulu ai i nā ʻāpana o ke kaumaha, nā ʻāpana o ka mania, a me nā ʻano ʻano ʻē aʻe ʻē aʻe). Hoʻohana pū ʻia ʻo Lurasidone me ka lithium (Lithobid) a i ʻole valproate (Depacon) e mālama ai i ke kaumaha i nā mākua me ka maʻi bipolar. Aia ʻo Lurasidone i kahi papa o nā lāʻau i kapa ʻia atypical antipsychotics. Hana ia ma ka hoʻololi ʻana i ka hana o kekahi mau mea kūlohelohe i ka lolo.


Hele mai ʻo Lurasidone ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia me kahi pāʻina (ma ka liʻiliʻi 350 mau calorie) i hoʻokahi manawa i ka lā. E lawe i ka lurasidone ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i lurasidone e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Mālama ʻo Lurasidone i ka schizophrenia a me ke kaumaha i ka poʻe me ka maʻi bipolar akā ʻaʻole ia e hoʻōla i kēia mau ʻano. He mau pule paha ka lōʻihi a lōʻihi paha ma mua o kou ʻike ʻana i ka pono piha o ka lurasidone. E hoʻomau i ka lawe ʻana i ka lurasidone ʻoiai inā maikaʻi ʻoe. Mai hooki i ka lawe ʻana i ka lurasidone me ka walaʻau ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i lurasidone,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka lurasidone, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa lurasidone. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i ka carbamazepine (Carbatrol, Epitol, Tegretol); clarithromycin (Biaxin, i Prevpac); ketoconazole; mibefradil; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); ritonavir (Norvir); St. John's wort; aiʻole voriconazole (Vfend). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka lurasidone inā ʻoe e lawe i kekahi o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: antidepressants; antihistamines; atazanavir (Reyataz); bosentan (Tracleer); diltiazem (Cardizem, Cartia, Taztia, Tiazac, nā mea ʻē aʻe); efavirenz (Sustiva, i Atripla); erythromycin (E.E.S., E-Mycin, Ery-Tab, nā mea ʻē aʻe); etravirine (Intelence); fluconazole (Diflucan); indinavir (Crixivan); ipratropium (Atrovent, i Combivent, i Duoneb); itraconazole (Sporanox); nā lāʻau e kaohi ai i ka hopohopo, nā mea hoʻohiamoe, nā lāʻau moe, a i ʻole nā ​​mea hoʻohiamoe; nā lāʻau e kaohi ai i ke kahe o ke koko; nā lāʻau lapaʻau no ka glaucoma, ka maʻi ʻōpū, ka maʻi neʻe, myasthenia gravis, ka maʻi maʻi Parkinson, nā maʻi palapū, a me nā pilikia urinary; modafinil (Provigil); nafcillin; nefazodone; nelfinavir (Viracept); phenobarbital; pioglitazone (Actos, ma Duetact, ma Actoplus Met); rifabutin (Mycobutin); aiʻole verapamil (Calan, Verelan, nā mea ʻē aʻe, ma Tarka); E launa pū paha nā lāʻau ʻē aʻe me lurasidone, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā ʻoe i hoʻohana a i hoʻohana paha i nā lāʻau i hele i ke alanui a i ʻole i hoʻohana nui ʻole i nā lāʻau i kuhikuhi ʻia a inā ʻoe i loaʻa i kahi maʻi hahau. kahi kuhina (TIA); ʻeha o ka umauma, maʻi puʻuwai, a i ʻole puʻuwai puʻuwai; he kuʻi puʻuwai kūpono ʻole; puʻuwai puʻuwai; Maʻi ʻo Parkinson (kahi maʻi o ka ʻōnaehana nīnūnē e kumu i nā pilikia me ka neʻe, ka hoʻokele ʻana i nā mākala, a me ke kaulike); Ka maʻi ʻo Alzheimer (kahi maʻi lolo e luku mālie i ka hoʻomanaʻo a me ka hiki ke noʻonoʻo, aʻo, kamaʻilio a lawelawe i nā hana o kēlā me kēia lā); ka hopu ʻana; dementia; maʻi ʻaʻai umauma; pilikia e mālama i kāu kaulike; i kekahi ʻano hana e paʻakikī iā ʻoe e ale; kiʻekiʻe a haʻahaʻa paha ke koko; nā pae prolactin kiʻekiʻe; kahi kiʻekiʻe o nā momona (kolesterol a me nā triglycerides) i loko o kou koko; kahi helu haʻahaʻa o nā hunaola keokeo; maʻi maʻi ʻōpū; maʻi maʻi akepaʻa; kō kō kiʻekiʻe; aiʻole inā ʻo ʻoe a i ʻole kekahi o kou ʻohana i loaʻa a loaʻa paha i ka maʻi diabetes. E haʻi i kāu kauka inā loaʻa ka luaʻi nui a i ʻole diarrhea a i ʻole nā ​​hōʻailona o ka make wai i kēia manawa, a i ʻole inā hoʻomohala ʻoe i kēia mau hōʻailona i kēlā me kēia manawa i kāu wā e lapaʻau ai. E haʻi pū i kāu kauka inā pono ʻoe e hoʻōki i ka lawe ʻana i kahi lāʻau no ka maʻi noʻonoʻo ma muli o nā hopena ʻino.
  • e haʻi i kāu kauka inā hāpai ʻoe, keu hoʻi inā ʻoe i nā mahina i hala hope o kou hāpai ʻana, a inā ʻoe e hoʻolālā e hāpai a i hānai waiu paha. Inā hāpai ʻoe i ka lawe ʻana i ka lurasidone, e kāhea i kāu kauka. Hoʻokumu paha ʻo Lurasidone i nā pilikia i nā keiki hānau hou ma hope o ka lawe ʻana inā lawe ʻia i nā mahina hope o ka hāpai ʻana.
  • inā ke ʻoki nei ʻoe, e like me ke ʻoki niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka lurasidone.
  • pono ʻoe e ʻike ʻo ka lurasidone paha ka mea e hiamoe ai iā ʻoe. Mai hoʻokele i kahi kaʻa a hana i nā mīkini weliweli a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.
  • pono ʻoe e ʻike e ʻike paha ʻoe i ka hyperglycemia (hoʻonui i kāu kō kō) ʻoiai ʻoe e lawe nei i kēia lāʻau, ʻoiai inā ʻaʻohe ou diabetes. Inā loaʻa iā ʻoe ka schizophrenia, ʻoi aku paha ka hoʻomohala ʻana i ka maʻi diabetes ma mua o ka poʻe i loaʻa ʻole ka schizophrenia, a ʻo ka lawe ʻana i ka lurasidone a i ʻole nā ​​lāʻau like e hoʻonui ai i kēia pilikia. E haʻi koke i kāu kauka inā loaʻa iā ʻoe kekahi o nā ʻōuli ma hope ke lawe nei ʻoe i ka lurasidone: make wai loa, mimiki pinepine, pololi loa, ʻike maka ʻole a nāwaliwali paha. He mea nui ia e kāhea aku i kāu kauka ke loaʻa koke iā ʻoe kekahi o kēia mau ʻōuli, no ka mea, hiki i ke kō kō ke kiʻekiʻe ke kumu i kahi kūlana koʻikoʻi i kapa ʻia ʻo ketoacidosis. Lilo paha ʻo Ketoacidosis i mea hoʻoweliweli i ke ola ke mālama ʻole ʻia ia i ka wā mua. ʻO nā ʻōuli o ketoacidosis e komo pū me ka waha maloʻo, kahe a me ka luaʻi, ka hanu o ka hanu, ka hanu e ʻaʻala i ka hua, a me ka emi o ka ʻike.
  • pono ʻoe e ʻike i ka lurasidone e hoʻonāukiuki ai, ʻālohilohi, a maule ai ke ala koke ʻoe mai kahi kūlana wahaheʻe. ʻOi aku ka maʻamau o kēia ke hoʻomaka mua ʻoe e lawe i ka lurasidone. I mea e pale ai i kēia pilikia, e hele mālie i waho o kahi moe, e hoʻomaha ana i kou mau wāwae i ka papahele no kekahi mau minuke ma mua o ke kū ʻana i luna.
  • pono ʻoe e ʻike he hana paʻakikī paha ka lurasidone i kou kino i ke anuanu ke hele a wela loa. E haʻi i kāu kauka inā ʻoe e hoʻolālā e hoʻolālā a ʻike ʻia i ka wela nui.
  • pono ʻoe e ʻike ʻo ka lurasidone paha ka mea e hoʻonui ai i ka kaupaona. He mea nui e nānā i kāu kau kaumaha i kēlā me kēia manawa ʻoiai ʻoe e lawe nei i kēia lāʻau.

Mai ʻai i ka nui o ka huaʻulu a inu paha i ka wai huaʻikuʻi i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala me ka meaʻai (ma ka liʻiliʻi 350 mau calorie) ke hoʻomanaʻo koke ʻoe iā ia. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu ʻo Lurasidone i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻino, hoʻoluhi, a i ʻole pilikia i ka mālama ʻana i kāu kaulike
  • hopohopo
  • nāwaliwali
  • luhi
  • hoʻomaha ʻole
  • luliluli ʻole ʻana i kahi ʻāpana o ke kino
  • neʻe lohi a hele wāwae shuffling paha
  • nausea
  • ka luaʻi
  • loli ka makemake
  • hoʻonui kohu
  • hoʻonui ka umauma a hoʻokuʻu paha
  • lohi a hala paha i ka wā menstrual
  • hoʻemi i ka moekolohe

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, a i ʻole nā ​​mea i helu ʻia ma nā ʻARlelo AOAO IMPORTANT a me nā WAIWAI HOU, e kelepona koke i kāu kauka:

  • ka hopu ʻana
  • ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • hulahula
  • pilikia i ka ale ʻana a me ka hanu ʻana
  • pokole o ka hanu
  • puʻuwai puʻuwai
  • ʻeha ka ʻāʻī, ke kuni, ka puʻu, ka haʻalulu, a me nā ʻōuli ʻē aʻe o ka maʻi
  • ke kuni, ka hou ʻana, ka huikau, ka wikiwiki o ka puʻuwai puʻuwai a i ʻole kaulike, a me ka ʻīʻī nui o nā io
  • neʻe ʻole o kou helehelena a kino paha i hiki ʻole iā ʻoe ke kāohi
  • hāʻule ʻana

Hoʻokumu paha ʻo Lurasidone i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka lurasidone.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 04/15/2018

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