Vorinostat

Anter

• Ma mua o ka lawe ʻana i ka vorinostat,
• Hoʻokumu paha ʻo Vorinostat i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

Hoʻohana ʻia ʻo Vorinostat e mālama i ka lymphoma T-cell cutaneous (CTCL, kahi ʻano maʻi ʻaʻai) i ka poʻe i hoʻomaikaʻi ʻole ʻia ko lākou maʻi, ua ʻoi aku ka maikaʻi, a ua hoʻi mai paha ma hope o ka lawe ʻana i nā lāʻau ʻē aʻe. Aia ʻo Vorinostat i loko o ka papa o nā lāʻau i kapa ʻia nā mea kāohi ʻo histone deacetylase (HDAC). Hana ia ma ka luku ʻana a hoʻokū ʻana paha i ka ulu ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Vorinostat ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka meaʻai. E haʻi aku kāu kauka iā ʻoe inā e lawe vorinostat i kēlā me kēia lā a i ʻole i kekahi mau lā o ka pule. E lawe i ka vorinostat ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka vorinostat. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule holoʻokoʻa; mai wehe, nau, a wāwahi paha iā lākou. Inā ʻaʻole hiki iā ʻoe ke ale i nā capsule holoʻokoʻa, e kāhea i kāu kauka. Inā wehe ʻia a hū ʻole ʻia nā capsule vorinostat, mai hoʻopā i nā capsule a i ka pauka. Inā loaʻa ka pauka mai kahi capsule hāmama a haki paha i kou ʻili a i ʻole i kou mau maka a ihu paha, holoi maikaʻi i ka wahi me ka nui o ka wai a kāhea i kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka vorinostat,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka vorinostat, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā capsule vorinostat. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven), belinostat (Beleodaq), a me valproic acid (Depakene). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa ʻoe i ka nūhou, ka luaʻi, a i ʻole ka maʻi pākī; a inā he aʻa koko paha kāu i loko o nā akemā a i ʻole he aa koko (ke koko); ke kō kiʻekiʻe a i ʻole ka maʻi kō. arrhythmia (pilikia o ka naʻau a i ʻole nā ​​pilikia o ka puʻuwai puʻuwai); nā pae haʻahaʻa o ka potassium a me ka magnesium, a me ka puʻuwai, nā puʻupaʻa, a me nā maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e lawe i kahi hōʻike hāpai keiki ma lalo o 7 mau lā ma mua o ka hoʻomaka ʻana i ka lāʻau. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe me kāu hoa wahine i hiki ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i kou wā e mālama ai a no 3 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe i ka lawe ʻana i ka vorinostat, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Vorinostat i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana i ka vorinostat a no 1 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i ka vorinostat e hiamoe ai ʻoe. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.
• pono ʻoe e ʻike ʻo ka vorinostat ke kumu o ka hoʻonui ʻia o ka glucose glucose. Inā loaʻa ʻoe i ka maʻi diabetes a i ʻole ke kō i ke koko kiʻekiʻe, e nānā i kāu kō kō e like me ke kuhikuhi a kāu kauka. Inā ʻoi aku ke kō o kou kō ma mua o ka maʻamau, e kāhea i kāu kauka. E haʻi koke i kāu kauka inā loaʻa iā ʻoe kekahi o nā ʻōuli ma hope ke lawe nei ʻoe i ka vorinostat: make wai loa, mimiki pinepine, pololi nui, ʻike maka ʻole, a nāwaliwali paha. He mea nui ia e kāhea aku i kāu kauka ke loaʻa koke iā ʻoe kekahi o kēia mau ʻōuli, no ka mea, ʻaʻole mālama ʻia ke kō koko kiʻekiʻe e mālama ʻia ai i kahi ʻano koʻikoʻi i kapa ʻia ʻo ketoacidosis. Lilo paha ʻo Ketoacidosis i mea hoʻoweliweli i ke ola ke mālama ʻole ʻia ia i ka wā mua. ʻO nā ʻōuli o ketoacidosis e komo pū me ka waha maloʻo, huhū ka ʻōpū a me ka luaʻi, ka hanu ʻana, ka hanu e ʻaʻala ana i ka hua, a me ka hoʻemi ʻana o ka ʻike. Kāhea i kāu kauka inā ʻaʻole hiki iā ʻoe ke ʻai a inu paha maʻamau ma muli o ka nausea, ka luaʻi ʻana, a i ʻole ka palahō ʻoiai ʻoe e lawe ana i ka vorinostat.

E hōʻoia e inu ma kahi o ʻewalu mau 8-auneke (240-milliliter) mau kīʻaha wai a i ʻole nā ​​wai ʻē aʻe i kēlā me kēia lā ke lawe nei ʻoe i ka vorinostat i ʻole ʻoe e maloʻo.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Vorinostat i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• nausea
• nalo ʻai ʻole
• Kaumaha emi
• ka luaʻi
• kōpaʻa
• luhi loa
• haʻalulu
• hoʻololi i ke ʻano o ka ʻono o nā mea
• waha maloo
• poho lauoho
• ʻūpā
• ka pehu ʻana o nā wāwae, nā wāwae, a me nā kuʻekuʻe wāwae
• ʻūlili
• ʻūhā
• fiva
• ʻeha poʻo
• ʻeha ka ʻili

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• kahe koko ʻole ʻana a palapū paha
• ʻili mae
• ʻōhū koke, ʻulaʻula, mehana, ʻeha, a me / a palupalu paha i ka wāwae
• ʻulaʻula a i ʻole hoʻololi i ke kala o ka ʻili
• ʻeha ʻeha kūkae
• pokole o ka hanu
• kahe ana ke koko
• ka houʻu ʻana
• puʻuwai wikiwiki
• maule ana
• hopohopo

Hoʻokumu paha ʻo Vorinostat i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka vorinostat.

Ma mua o ka hoʻāʻo ʻana i kahi keʻena hoʻokolohua, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua e lawe nei ʻoe i vorinostat.

Mai ʻae i kekahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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