Voriconazole

Anter

• Ma mua o ka lawe ʻana i voniconazole,
• Hiki i ka Voriconazole ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā WAIHUAHU MAKAHIKI, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana ʻia ʻo Voriconazole i nā mākua a me nā keiki ʻo 2 mau makahiki a ʻoi aku ka nui e mālama ai i nā maʻi fungal koʻikoʻi e like me ka aspergillosis invasive (kahi maʻi fungal e hoʻomaka i nā akemāmā a pālahalaha ma o ke kahe o ke koko i nā mea ʻē aʻe), candidiasis esophageal (kahi hū [kahi ʻano fungus] maʻi hiki ke kumu i keʻokeʻo patching i loko o ka waha a me ka puʻu), a me ka candidemia (he fungal maʻiʻaʻai i loko o ke koko). Hoʻohana ʻia ia e mālama i kekahi mau maʻi fungal ʻē aʻe ke holo ʻole nā ​​lāʻau ʻē aʻe no kekahi mau mea maʻi. Aia ʻo Voriconazole i kahi papa o nā lāʻau antifungal i kapa ʻia ʻo triazoles. Hana ia me ka hoʻolohi i ka ulu ʻana o nā fungi i kumu i ka maʻi.

Hele mai ʻo Voriconazole ma ke ʻano he papa a me kahi hoʻomaha (wai) e lawe ma ka waha. Lawe ʻia ia i kēlā me kēia 12 hola ma kahi ʻōpū hakahaka, ma ka liʻiliʻi he 1 hola ma mua a i ʻole 1 hola ma hope o ka pāʻina ʻana. I mea e kōkua ai iā ʻoe e hoʻomanaʻo e lawe i ka voriconazole, e lawe ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka voriconazole. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā ʻoe e lawe ana i ka hoʻokuʻu voriconazole, hoʻoluliluli i ka ʻōmole paʻa ma kahi o 10 kekona ma mua o kēlā me kēia hoʻohana ʻana e hui pono i ka lāʻau. Mai hoʻopili i ka hoʻomaha me nā lāʻau ʻē aʻe, ka wai, a i ʻole nā ​​wai ʻē aʻe. E hoʻohana mau i ka mīkini ana e hiki mai ana me kāu lāʻau. ʻAʻole paha ʻoe e loaʻa i ka nui o ka lāʻau lapaʻau inā hoʻohana ʻoe i ka puna o ka home e ana i kāu lāʻau.

I ka hoʻomaka ʻana o kāu lapaʻau ʻana, loaʻa paha iā ʻoe ka voriconazole e ke kahena intravenous (i loko o kahi aa). Ke hoʻomaka ʻoe i ka lawe ʻana i ka voriconazole e ka waha, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi lāʻau haʻahaʻa a hoʻonui i kāu lāʻau inā ʻaʻole hoʻomaikaʻi kāu ʻano. Hiki i kāu kauka ke hōʻemi i kāu lāʻau inā ʻike ʻoe i nā hopena ʻē aʻe mai voriconazole.

Pili ka lōʻihi o kāu lapaʻau i kou olakino laula, ke ʻano o ka maʻi i loaʻa iā ʻoe, a pehea kou pane maikaʻi ʻana i ka lāʻau. E hoʻomau i ka lawe ʻana i voniconazole ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka voriconazole me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i voniconazole,

• e haʻi aku i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka voriconazole, nā lāʻau antifungal ʻē aʻe e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), a i ʻole ketoconazole (Nizoral); nā lāʻau ʻē aʻe, lactose, a i ʻole kekahi o nā mea ʻē aʻe i loko o nā papa voriconazole. a me ka hoʻomaha ʻana. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hana i nā papa voriconazole a me ka hoʻomaha ʻana.
• mai lawe i ka voriconazole inā lawe ʻoe i kekahi o nā lāʻau aʻe: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); cisapride (Propulsid); efavirenz (Sustiva, i Atripla); nā lāʻau lapaʻau ergot-type e like me dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (Ergomar, ma Cafergot, ma Migergot), a me methylergonovine (Methergine); ivabradine (Corlanor); naloxegol (Monvatik); phenobarbital; pimozide (Orap); quinidine (i Nuedexta); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); ritonavir (Norvir, ma Kaletra); sirolimus (Rapamune); St. John's wort; tolvaptan (Jynarque, Samsca); a me ka venetoclax (Venclexta).
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā huaora, a me nā mea hoʻopono pono ʻē aʻe āu e lawe nei. E hōʻoia e haʻi i kekahi o kēia mau mea: anticoagulants ('nā mea hōʻemi koko') e like me warfarin (Coumadin, Jantoven); nā benzodiazepines e like me alprazolam (Niravam, Xanax), midazolam, a me triazolam (Halcion); nā poloka kalipuna e like me amlodipine (Norvasc, ma Amturnide, ma Tekamlo), felodipine (Plendil), isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), nimodipine (Nymalize), a me nisoldipine (Sular); nā lāʻau hoʻohaʻahaʻa kolesterol (statins) e like me atorvastatin (Lipitor, ma Caduet, ma Liptruzet), fluvastatin (Lescol), lovastatin (Altoprev, ma Advicor), pravastatin (Pravachol), a me simvastatin (Zocor, ma Simcor, i Vytorin); cyclosporine (Gengraf, Neoral, Sandimmune); everolimus (Afinitor, Zortress); fentanyl (Abstral, Actiq, Fentora, Lazanda, Subsys); nā lāʻau no ka maʻi kō e like me glipizide (Glucotrol), glyburide (Diabeta, Glynase,, i Glucovance), a me tolbutamide; nā lāʻau no ka HIV e like me delavirdine (Rescriptor), nelfinavir (Viracept), nevirapine (Viramune), a me saquinavir (Invirase); methadone (Dolophine, Methadose); nā lāʻau lapaʻau anti-inflammatory nonsteroidal (diclofenac, ibuprofen), nā pale pale waha; ʻoxycodone (Oxecta, Oxycontin, ma Oxycet, ma Percocet, ma Percodan, ma Roxicet, ma Xartemis); phenytoin (Dilantin, Phenytek); nā mea pale proton-pump e like me esomeprazole (Nexium, i Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, in Prevpac), pantoprazole (Protonix), a me rabeprazole (AcipHex); tacrolimus (Astagraf, Prograf); vinblastine; a me ka vincristine. Nui paha nā lāʻau ʻē aʻe e launa pū paha me voriconazole, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā ua mālama ʻia ʻoe me nā lāʻau chemotherapy no ka maʻi ʻaʻai, a inā ua loaʻa a loaʻa paha iā ʻoe kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hoʻonāukiuki ai ka puʻuwai ʻole, maʻule paha, a make koke paha), a i ʻole inā ua loaʻa i kahi puʻuwai lohi a kaulike ʻole paha, nā pae koko haʻahaʻa o ka potassium, ka magnesium, a me ka calcium, cardiomyopathy (hoʻonui a mānoanoa paha i ka puʻuwai puʻuwai e hoʻokū i ka puʻuwai mai ka pīpī ʻana i ke koko ma ke ʻano maʻamau), maʻi ʻaʻai o nā aʻa o ke koko, ka hoʻomanawanui ʻole galactose a i ʻole glucose – galactose malabsorption ( nā kūlana hoʻoilina i hiki ʻole i ke kino ke hoʻomanawanui i ka lactose); i kekahi ʻano hana paʻakikī iā ʻoe e ʻānai i ka sukiko (pāpaʻa kō) a i ʻole ka lactose (i loaʻa i ka waiū a me nā huahana waiū), a i ʻole ka maʻi ate a me nā puʻupaʻa.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i voriconazole. Pono ʻoe e hoʻohana i ka kaohi hānau kūpono e pale ai i ka hāpai ʻana i kāu wā mālama me voriconazole. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i voniconazole, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Voriconazole i ka fetus.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i voralonazole.
• pono ʻoe e ʻike he hiki i ka voriconazole ke kumu i ka ʻike maka a i ʻole nā ​​pilikia ʻē aʻe me kāu maka maka a hoʻoweliweli i kou mau maka i ke kukui ʻōlinolino. Mai hoʻokele i kahi kaʻa i ka pō ʻoiai e lawe ana i voriconazole. Mai hoʻokele i kahi kaʻa i ka lā a i ʻole hana i nā mīkini inā he pilikia paha kāu me kāu ʻike ke lawe nei ʻoe i kēia lāʻau.
• e hoʻolālā e hōʻalo i ka hōʻike kūpono ʻole a hoʻolōʻihi ʻia paha i ka lā a komo i nā lole pale, nā aniani aniani, a me ka sunscreen. Hoʻomaopopo paha ʻo Voriconazole i kou ʻili i ka lā o ka lā.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Voriconazole ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻike maka ʻole
• ka paʻakikī ʻike ʻana i nā kala
• pāhoehoe
• nausea
• ka luaʻi
• ʻeha poʻo
• ʻūpā
• waha maloo
• ʻōhinu

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā WAIHUAHU MAKAHIKI, e kāhea koke i kāu kauka:

• fiva
• haʻalulu a luliluli paha
• puʻuwai wikiwiki
• hanu wikiwiki
• huikau
• hoʻohuhū ʻōpū
• luhi loa
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• nalo ʻai ʻole
• ka ʻume, ka mimi ʻeleʻele, ka pau ʻole o ka makemake, ka luhi, ka melemele ʻana o ka ʻili a me nā maka, ka ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, nausea, ka luaʻi, a me nā hōʻailona like flu.
• luhi; nele i ka ikaika; nāwaliwali; nausea; ka luaʻi; ʻūpā; ka pohō kaumaha, a i ʻole ka ʻeha o ka ʻōpū
• loaʻa ke kaupaona; puʻu momona ma waena o nā poʻohiwi; helehelena poepoe (alo mahina); ʻeleʻele o ka ʻili ma ka ʻōpū, ʻūhā, nā umauma, a me nā lima; ʻili lahilahi; ʻāpala; ʻoi nui ka ulu ʻana o ka lauoho; a sweating paha
• hallucination (ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole ola)
• ʻeha o ka umauma a i ʻole ke kūiki
• hūwī
• ka houʻu ʻana
• hives a ʻiliʻili paha
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo

Hiki i ka Voriconazole ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i nā papa i ka mahana o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i loko o ka lua. E mālama i ka hoʻokuʻu waha ʻole i hoʻohui ʻia i loko o ka pahu hau, akā i ka manawa e hoʻopili ʻia ia i kahi keena wela a mai hoʻopili iā ia. E hoʻolei i kahi hoʻomaha hoʻomaha ʻole ma hope o 14 mau lā.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻike i ka mālamalama
• nā haumāna ākea (nā pōʻaiʻeleʻele i ka waena o nā maka)
• maka paʻa
• paheʻe
• nalo o ke kaulike ʻoiai e neʻe ana
• kaumaha
• pokole o ka hanu
• ka hopu ʻana
• ʻōpū pehu
• luhi loa

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā voriconazole.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi. Inā loaʻa iā ʻoe nā ʻōuli o ka maʻi ma hope o kou hoʻopau ʻana i ka voriconazole, e kāhea i kāu kauka.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Vfend^®