Mea Kākau: Virginia Floyd
Lā O Ka Hana: 10 Aukake 2021
HōʻAno Hou I Ka Lā: 15 Nowemapa 2024
Anonim
FDA Urges Caution Over Long-Term Use of Bone-Density-Building Drugs
Wikiō: FDA Urges Caution Over Long-Term Use of Bone-Density-Building Drugs

Anter

Hoʻohana ʻia nā papa Risedronate a hoʻokuʻu ʻia (hoʻokuʻu lōʻihi) e pale a mālama i ka osteoporosis (kahi ʻano e lahilahi a nāwaliwali ai nā iwi a haki maʻalahi) i nā wahine i loaʻa i ka menopause ("hoʻololi o ke ola," hopena o nā wā menstrual). Hoʻohana ʻia nā papa Risedronate e mālama i ka osteoporosis i loko o nā kāne, a i nā kāne a me nā wahine e lawe nei i nā glucocorticoids (kahi ʻano o ka lāʻau corticosteroid i kumu ʻia ai ka osteoporosis). Hoʻohana ʻia nā papa Risedronate e mālama i ka maʻi o Paget o ka iwi (kahi ʻano palupalu a nāwaliwali nā iwi a hemahema paha, ʻeha, a haki ʻole ʻia paha). Aia ʻo Risedronate i kahi papa o nā lāʻau i kapa ʻia ʻo bisphosphonates. Hana ia ma ka pale ʻana i ka haʻihaʻi iwi a me ka hoʻonui ʻana i ka iwi iwi (mānoanoa).

Hele mai ʻo Risedronate ma ke ʻano he papaha a me kahi papa hoʻolōʻihi hoʻokuʻu ʻia e lawe ma ka waha. Lawe pinepine ʻia nā papa hoʻokuʻu hoʻokuʻu lohi i hoʻokahi manawa i ka pule i ke kakahiaka, ma hope koke o ka ʻaina kakahiaka. Lawe pinepine ʻia nā papa i ka ʻōpū nele i hoʻokahi manawa i ka lā i ke kakahiaka, hoʻokahi manawa i kēlā me kēia pule i ke kakahiaka, hoʻokahi manawa i kēlā me kēia mahina i ke kakahiaka, a i ʻole hoʻokahi mahina no ʻelua mau kakahiaka i ka lālani e pili ana i kāu kūlana a me nā mea i kauoha ʻia e kāu kauka. Inā ʻoe e lawe i ka risedronate hoʻokahi i hoʻokahi pule, hoʻokahi mahina, a i hoʻokahi manawa no kēlā me kēia 2 lā i ka lālani, e lawe iā ia i ka lā like i kēlā me kēia pule a mahina paha a i ʻole 2 mau lā i ka lālani i kēlā me kēia mahina. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka risedronate. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia a i ʻole no kahi manawa lōʻihi ʻoi aku ka manawa i kau ʻia e kāu kauka.


ʻAʻole hiki ke hana pono ʻo Risedronate a hōʻino paha i ka esophagus (ka paipu e hoʻopili i ka waha a me ka ʻōpū) a i ʻole ke kumu e ʻeha ai ka waha inā ʻaʻole e lawe ʻia e like me nā kuhikuhi aʻe E haʻi i kāu kauka inā ʻaʻole ʻoe e maopopo, ʻaʻole ʻoe e noʻonoʻo e hoʻomanaʻo ʻoe, a i ʻole hiki ʻole iā ʻoe ke hāhai i kēia mau ʻōlelo aʻo.

  • Pono ʻoe e lawe i nā papa risedronate ma hope koke iho o kou ala ʻana i waho o kahi moe i kakahiaka a ma mua o kou ʻai ʻana a inu paha i kekahi mea. Pono ʻoe e lawe i nā papa hoʻopaneʻe hoʻopaneʻe ʻia ʻo risedronate ma hope koke o ka ʻaina kakahiaka. Mai lawe risedronate i ka wā moe a ma mua o kou ala ʻana a hele i waho o kahi moe no ka lā.
  • E hoʻopau i nā papa me ke kīʻaha piha (6 a 8 auneke [180 a 240 mL]) o ka wai maʻamau ʻoiai ʻoe e noho ana a i ʻole e kū ana. E ale i nā papa hoʻokuʻu hoʻokuʻu lohi me ka liʻiliʻi he 4 auneke (120 mL) o ka wai maʻamau ʻoiai ʻoe e noho ana a i ʻole e kū ana. Mai lawe i ka risedronate me ke kī, kope, wai, wai mineral, waiū, nā mea inu waiū ʻē aʻe, a i ʻole nā ​​wai ʻē aʻe ma mua o ka wai maʻamau.
  • E ale i nā papa a hoʻopau i nā papa hoʻokuʻu lohi. Mai hoʻokaʻawale, a nau, a ʻāpala paha iā lākou. Mai omo i nā papa a hoʻopaʻa iā lākou i kou waha no kekahi lōʻihi.
  • Ma hope o kou lawe ʻana i ka risedronate, mai ʻai, inu, a i ʻole lawe i nā lāʻau ʻē aʻe ma kahi o 30 mau minuke. Mai moe i lalo no 30 mau minuke ma hope o kou lawe ʻana i ka risedronate. Noho kū a kū i luna a hala ka hala o 30 mau minuke.

Mālama ʻo Risedronate i ka osteoporosis a me ka maʻi o Paget o ka iwi akā ʻaʻole ia e hoʻōla i kēia mau ʻano. Kōkua ʻo Risedronate e mālama a pale i ka osteoporosis ʻoiai ke lawe mau ʻia ia. E hoʻomau i ka risedronate ʻoiai ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka risedronate me ke kamaʻilio ʻole ʻana me kāu kauka, akā e kamaʻilio me kāu kauka mai kēlā me kēia manawa e pili ana inā pono ʻoe e lawe i ka risedronate.


E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka ʻikepili ʻike hoʻomanawanui o ka mea hana (Ke alakaʻi alakaʻi) ke hoʻomaka ʻoe i ka lāʻau me risedronate a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka risedronate,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka risedronate, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa risedronate a i ʻole nā ​​papa hoʻokuʻu hoʻokuʻu lohi. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E hoʻomaopopo pono e haʻi i kekahi o kēia mau mea: angiogenesis nā mea kāohi e like me bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), a sunitinib (Sutent); aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Ibu-Tab, Motrin, a me nā mea ʻē aʻe) a me naproxen (Aleve, Naprelan, Naprosyn, a me nā mea ʻē aʻe); chemotherapy maʻi ʻaʻai; aiʻole nā ​​steroid oral e like me dexamethasone, methylprednisolone (Medrol), a me prednisone (Rayos). Inā ʻoe e lawe i nā papa hoʻokuʻu hoʻokuʻu lohi, pono ʻoe e haʻi i kāu kauka inā lawe ʻoe i kahi H2 blocker e like me cimetidine, famotidine (Pepcid), nizatidine (Axid), a me ranitidine (Zantac) a i ʻole ka proton pump pump like esomeprazole (Nexium, i Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix ), a me ka rabeprazole (AcipHex). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • pono ʻoe e ʻike ʻo Actonel lāua ʻo Atelvia nā risedronate ʻelua. ʻAʻole hiki iā ʻoe ke lawe i kēia mau lāʻau i ka manawa like.
  • inā ʻoe e lawe i nā lāʻau waha ʻē aʻe e like me nā wikamina, nā mea hoʻopili, a i ʻole nā ​​antacids, e lawe iā lākou ma 30 mau minuke ma hope o kou lawe ʻana i ka risedronate.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe kahi pae haʻahaʻa o ka calcium i loko o kou koko a i ʻole nā ​​pilikia me kāu esophagus a inā ʻaʻole hiki iā ʻoe ke noho kū aʻe a kū pololei paha ma kahi o 30 mau minuke. E haʻi paha kāu kauka iā ʻoe ʻaʻole pono ʻoe e lawe i ka risedronate.
  • e haʻi i kāu kauka inā ʻoe e hana i ka radiation radiation; inā ua pilikia paha ʻoe i ka ale ʻana; puʻuwai puʻuwai; ulcer a i ʻole nā ​​pilikia ʻē aʻe me kou ʻōpū; anemia (ke ʻano a i ʻole e lawe mai nā hunaola ʻulaʻula i lawa ka oxygen ma nā ʻāpana āpau o ke kino); maʻi ʻaʻai; kekahi ʻano maʻi, ʻoi loa i kou waha; nā pilikia me kou waha, nā niho, a i ʻole nā ​​gum; i kekahi ʻano e hōʻoki i kou koko mai ka hoʻopili ʻana maʻamau; aiʻole ka maʻi niho a ʻino paha.
  • e haʻi i kāu kauka inā hāpai ʻoe a hānai waiu paha. E haʻi aku i kāu kauka inā ʻoe e hoʻolālā e hāpai i kēlā me kēia manawa i ka wā e hiki mai ana, no ka mea e noho ka risedronate i loko o kou kino i mau makahiki ma hope o kou hōʻoki ʻana i ka lawe. Kāhea i kāu kauka inā hāpai ʻoe i ka wā a ma hope paha o kāu mālama ʻana me risedronate.
  • pono ʻoe e ʻike ʻo ka risedronate ke kumu o ka iwi nui, nā mākala, a me nā ʻeha pū. E hoʻomaka paha ʻoe e ʻeha i kēia ʻeha i loko o nā lā, mau mahina, a mau makahiki paha ma hope o kou lawe mua ʻana i ka risedronate. ʻOiai ʻo kēia ʻano ʻeha e hoʻomaka paha ma hope o kou lawe ʻana i risedronate no kekahi manawa, he mea nui ia no ʻoe a me kāu kauka e hoʻomaopopo ai no ka risedronate paha ia. Kāhea koke i kāu kauka inā ʻike ʻoe i ka ʻehaʻeha loa i kēlā me kēia manawa i kāu mālama ʻana me ka risedronate. E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka risedronate a hele aku paha kou ʻeha ma hope o kou hōʻoki ʻana i ka lawe ʻana i ka lāʻau.
  • pono ʻoe e ʻike he ala ka risedronate i ka osteonecrosis o ka iwi ā (ONJ, kahi kūlana koʻikoʻi o ka iwi ā), keu hoʻi inā he ʻoki niho ʻoe a i ʻole ke mālama ʻana ʻoiai ʻoe e lawe nei i ka lāʻau. Pono kahi kauka niho e nānā i kou mau niho a hana i nā hana e pono ai, e like me ka hoʻomaʻemaʻe a me ke hoʻoponopono ʻana i nā niho pono ʻole, ma mua o kou hoʻomaka ʻana e lawe i ka risedronate. E mālama pono i kou niho a hoʻomaʻemaʻe i kou waha pono ʻoiai ʻoe e lawe nei i ka risedronate. E kamaʻilio me kāu kauka ma mua o ka loaʻa ʻana o nā lāʻau lapaʻau iā ʻoe e lawe nei i kēia lāʻau.
  • e kamaʻilio me kāu kauka e pili ana i nā mea ʻē aʻe hiki iā ʻoe ke hana e pale aku ai i ka osteoporosis mai ka hoʻomohala ʻana a i ʻole ka hōʻino ʻana. E haʻi paha kāu kauka iā ʻoe e hōʻalo i ka puhī ʻana a me ka inu ʻana i ka nui o ka waiʻona a e hāhai i kahi papahana maʻamau o ka hoʻoikaika kino.

Pono ʻoe e ʻai i nā meaʻai he nui i ka puna a me ka wikamina D ke lawe ʻoe i ka risedronate. E haʻi aku kāu kauka iā ʻoe i nā meaʻai nā kumu waiwai maikaʻi o kēia mau meaola a me ka nui o nā lawelawe āu e pono ai i kēlā me kēia lā. Inā paʻakikī ʻoe e ʻai lawa i kēia mau meaʻai, e haʻi i kāu kauka. I kēlā hihia, hiki i kāu kauka ke kauoha a koi paha i kahi mea hoʻopiha.


Inā ʻoe e ʻike i kahi mahele o risedronate hoʻokahi lā, mai lawe ia ma hope i ka lā. Hōʻalo i ka lāʻau i hala a lawe i hoʻokahi mahele i ke kakahiaka aʻe e like me ka mau.

Inā ʻoe e ʻike i kahi mahele o risedronate hoʻokahi pule, mai lawe ia ma hope i ka lā. E lawe i hoʻokahi mahele lāʻau i ke kakahiaka ma hope o kou hoʻomanaʻo. A laila hoʻi i ka lawe ʻana i hoʻokahi mahele lāʻau hoʻokahi i kēlā me kēia pule ma kāu lā i hoʻonohonoho mau ʻia.

Inā ʻoe e nalo i kahi mahele o ka risedronate hoʻokahi mahina akā e hoʻomanaʻo ma mua o 7 mau lā ma mua o kāu kau palena hope e lawe ai, e lawe i ka lāʻau i hala i ke kakahiaka ma hope o kou hoʻomanaʻo. Inā hoʻomanaʻo ʻoe ma lalo o 7 mau lā ma mua o kāu kau palena hope e hoʻonohonoho ʻia, mai lawe i ka lāʻau i hala. Ma kahi o, kali a kakahiaka o kāu kau palena hope aʻe a laila e risedronate e like me ka mau.

Inā ʻoe e nalo i hoʻokahi a i ʻole ʻelua mau kaha o nā lā ʻelua i ka lālani, hoʻokahi risedronate i kēlā me kēia mahina akā hoʻomanaʻo ʻoi aku ma mua o 7 mau lā ma mua o kāu kau ʻia i hoʻonohonoho ʻia aʻe nei, hiki iā ʻoe ke lawe i nā ʻalo i hala. E lawe i ka lāʻau i hala mua i ke kakahiaka ma hope o kou hoʻomanaʻo ʻana a inā ua hala ʻoe i nā kaha ʻelua, lawe i ka lua o nā nalo i hala i ke kakahiaka ma hope o kou lawe ʻana i ka mua. Inā hoʻomanaʻo ʻoe ma lalo o 7 mau lā ma mua o kāu kau palena hope e hoʻonohonoho ʻia, mai lawe i nā lāʻau i hala. Ma kahi o, kali a kakahiaka o kāu kau palena hope aʻe a laila e risedronate e like me ka mau.

Inā haʻalele ʻoe i nā lāʻau o ka risedronate a ʻike ʻole i ka mea e hana ai, e kāhea i kāu kauka. Lawe mau i ka risedronate mea mua i ke kakahiaka. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala, a mai lawe i hoʻokahi lāʻau i hoʻokahi lā.

Hoʻokumu paha ʻo Risedronate i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nausea
  • hoʻolewa
  • waha maloo
  • ʻeha ka ʻōpū
  • pāhoehoe
  • kōpaʻa
  • ʻenekini
  • ʻeha poʻo
  • ʻūpā
  • nāwaliwali
  • ʻūhā wāwae
  • ʻeha kua
  • Pono pinepine a koi paha e mimi
  • urination ʻeha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā loaʻa iā ʻoe kekahi o nā hopena aʻe, e kāhea koke i kāu kauka ma mua o kou lawe ʻana i kahi risedronate hou aʻe.

  • pilikia i ka ale ʻana a i ʻole ka ʻeha ke ale
  • puʻuwai puʻuwai hou a ʻoi aku paha
  • ʻeha ka umauma
  • ʻūlili
  • hūwī
  • hives
  • pālahalaha i ka ʻili
  • ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • paʻakikī i ka hanu ʻana
  • hulahula
  • spasms Muscle, twitching, a i ʻole ke ʻūlū
  • numbness a i ʻole tingling a puni ka waha a i ʻole i nā lima a i ʻole nā ​​wāwae
  • pehu, ʻulaʻula, a ʻehaʻeha paha nā maka
  • ʻike i ka mālamalama
  • gums ʻeha a pehu paha
  • ka hemo ʻana o nā niho
  • ʻōniu a kaumaha paha i ka ā ā
  • hoʻōla maikaʻi ʻole o ka iwi ā
  • puʻupuʻu, ʻeha ʻeha ma nā pūhaka, ʻūlū, a i ʻole nā ​​ʻūhā

Hoʻokumu paha ʻo Risedronate i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

ʻO ka lawe ʻana i kahi lāʻau bisphosphonate e like me risedronate no ka osteoporosis e hoʻonui ai i ka makaʻu e haki ʻoe i kou iwi ʻūhā. ʻIke paha ʻoe i ka ʻeha ma kou pūhaka, ʻūlū, a me nā ʻūhā no mau pule a i ʻole mau mahina ma mua o ka haki ʻana o ka iwi, a ʻike paha ʻoe ua haki kekahi o nā iwi o kou ʻūhā ʻoiai ʻaʻole ʻoe i hāʻule a i ʻole ʻike i kekahi ʻeha ʻē aʻe.He mea maʻamau ʻole ka haki ka iwi o ka ʻūhā i ka poʻe olakino, akā ʻo ka poʻe i loaʻa ka osteoporosis e haki paha i kēia iwi inā ʻaʻole lākou e lawe i ka risedronate. E kamaʻilio me kāu kauka e pili ana i nā makaʻu o ka lawe ʻana i ka risedronate.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Inā loaʻa ka overdose, e hāʻawi i ka mea i loaʻa i ke kīʻaha piha o ka waiū a kāhea i kāu kikowaena lāʻau make kūloko ma 1-800-222-1222. Inā ua hāʻule ka mea i hōʻeha a ʻaʻole hanu paha, e kāhea i nā lawelawe kūloko kūloko ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • numbness a i ʻole tingling a puni ka waha a i ʻole i nā lima a i ʻole nā ​​wāwae
  • spasms muscle, cramp, a i ʻole twitches
  • ka hopu ʻana

E mālama i nā manawa a pau me kāu kauka a me ka hale hana.

Ma mua o ka hoʻokolohua ʻana a me ka hoʻopaʻa ʻana i nā kiʻi iwi, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua e lawe nei ʻoe i ka risedronate.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Actonel®
  • Atelvia
  • Actonel® me ka pōhaku (i loaʻa i ka aila, Risedronate)
Nānā Hou - 01/15/2016

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