Apolipoprotein CII

ʻO Apolipoprotein CII (apoCII) kahi protein i loaʻa i nā mea momona momona nui e lawe ʻia e ka gastrointestinal tract. Loaʻa iā ia i ka lipoprotein haʻahaʻa haʻahaʻa (VLDL), i hana ʻia e nā triglycerides (kahi ʻano momona i kou koko).

Kūkākūkā kēia ʻatikala i ka hoʻokolohua i hoʻohana ʻia e nānā no apoCII i kahi hāpana o kou koko.

Pono kahi laʻana koko.

ʻ toldlelo ʻia ʻoe ʻaʻole e ʻai a inu paha i kekahi mea no 4 a 6 mau hola ma mua o ka hoʻāʻo.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, ʻike paha ʻoe i kahi ʻeha, a i ʻole he kuʻi a i ʻole kui. A ma hope, aia paha kahi ʻōniʻoniʻo kahi i hoʻokomo ʻia ai ka nila.

Hiki i nā ana ApoCII ke kōkua i ka hoʻoholo ʻana i ke ʻano a me ke kumu o nā momona o ke koko kiʻekiʻe. ʻAʻole maopopo inā ʻo nā hopena hōʻike e hoʻomaikaʻi ai i ka lāʻau. Ma muli o kēia, ʻaʻole uku ka hapa nui o nā ʻoihana ʻinikua no ka hōʻoia. Inā ʻaʻohe ou kolesterol kiʻekiʻe a i ʻole maʻi maʻi puʻuwai a i ʻole ka moʻolelo ʻohana o kēia mau ʻano, ʻaʻole paha e paipai ʻia kēia hōʻike iā ʻoe.

ʻO ka pae maʻamau ʻo 3 a 5 mg / dL. Eia nō naʻe, hōʻike pinepine ʻia nā hopena a apoCII ma ke ʻano he ʻānō a i ʻole ma kahi e.

ʻO nā laʻana ma luna he ana maʻamau no nā hopena o kēia mau hoʻāʻo. Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio me kāu kauka e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

ʻO nā pae kiʻekiʻe o apoCII ma muli paha o ka moʻolelo ʻohana o ka hemahema lipoprotein lipase. He kūlana kēia e wāwahi ʻole ai ke kino i nā momona maʻamau.

ʻIke ʻia nā pae ApoCII i ka poʻe me kahi ʻano laha ʻole i kapa ʻia he deficit apoprotein ʻohana CII. ʻO kēia ke kumu o ka chylomicronemia Syndrome, kahi ʻano ʻē aʻe i wāwahi ʻole ai ke kino i nā momona maʻamau.

ʻO nā pōpilikia e pili ana i ke kau ʻana o ke koko he mea liʻiliʻi akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Hāʻawi paha nā ana o Apolipoprotein i nā kikoʻī e pili ana i kāu makaʻu no ka maʻi puʻuwai, akā ʻike ʻole ʻia ka waiwai i hoʻohui ʻia o kēia hoʻāʻo ma waho o kahi lipid panel.

ApoCII; Apoprotein CII; ApoC2; Ka hemahema Lipoprotein lipase - apolipoprotein CII; Chylomicronemia syndrome - apolipoprotein CII

• Hōʻaʻo koko

ʻO Chen X, Zhou L, Hussain MM. Lipids a me ka dislipoproteinemia. I: McPherson RA, Pincus MR, hua. ʻO kā Henry's Clinical Diagnosis a me Management e nā Laboratory Methods. 23rd Ed. St Louis, MO: Elsevier; 2017: chap 17.

ʻO Genest J, Libby P. Nā maʻi lipoprotein a me nā maʻi maʻi ʻōpū. I: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. ʻO ka maʻi puʻuwai ʻo Braunwald: He puke aʻo no ka lāʻau Cardiovascular. 11th hua. Piladelapia, PA: Elsevier; 2019: chap 48.

Remaley AT, Days Spring TD, Warnick GR. Lipids, lipoproteins, apolipoproteins, a me nā mea ʻē aʻe o ka maʻi puʻuwai. I: Rifai N, ed. ʻO Tietz Textbook of Clinical Chemistry a me nā Molecular Diagnostics. ʻElua huaʻōlelo St Louis, MO: Elsevier; 2018: chap 34.

Robinson JG. Nā maʻi o ka lipid metabolism. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 195.