ʻO Neuroblastoma

ʻO Neuroblastoma kahi ʻano laha loa o ka tumo maʻi ʻaʻai e hoʻomohala ʻia mai nā aʻa nerve. Hana ʻia ia i nā pēpē a me nā keiki.

Hiki i ka Neuroblastoma ke hana i nā wahi he nui o ke kino. Hoʻolālā ia mai nā mākia e hana i ka ʻōnaehana nūnē sympathetic. ʻO kēia kahi ʻāpana o ka ʻōnaehana hopohopo e kaohi i nā hana o ke kino, e like me ka nui o ka puʻuwai a me ke kahe o ke koko, digestion, a me nā pae o kekahi mau hormones.

Hoʻomaka ka hapa nui o nā neuroblastomas i loko o ka ʻōpū, i ka adrenal gland, ma ka ʻaoʻao o ka iwi kuamoʻo, a i ʻole i ka umauma. Hiki i nā Neuroblastomas ke pālahalaha i nā iwi. Pili nā iwi i ka maka, ka iwi poʻo, pelvis, poʻohiwi, lima, a me nā wāwae. Hiki iā ia ke pālahalaha i ka iwi iwi, ke ake, nā pūnana lymph, ka ʻili, a puni nā maka (orbits).

ʻAʻole ʻike ʻia ke kumu o ka tumo. Manaʻo ka poʻe loea i kahi kīnā i nā gen. Aia ka hapalua o nā tumors i ka wā hānau. Hoʻomaopopo pinepine ʻia ʻo Neuroblastoma i nā keiki ma mua o ka makahiki 5. I kēlā me kēia makahiki aia ma kahi o 700 mau hihia hou i United States. Hoʻonui iki ka maʻi i nā keikikāne.

I ka hapanui o ka poʻe, ua pālahalaha ka ʻōpū i ka wā e ʻike mua ʻia ai.

ʻO nā ʻōuli mua he kuni, kahi manaʻo maʻi maʻamau (malaise), a me ka ʻeha. Loaʻa paha i ka lilo o ka makemake, ka pohō kaumaha, a me ka palahī.

Aia nā ʻōuli ʻē aʻe i ka pūnaewele o ka tumo, a e hoʻopili pū paha me:

• ʻEha iwi a palupalu paha (inā ua pālahalaha ka maʻi ʻaʻai i nā iwi)
• Ka hanu paʻakikī a i ʻole ka uha mau (inā ua pālahalaha ka maʻi ʻaʻai i ka umauma)
• ʻO ka ʻōpū hoʻonui ʻia (mai kahi tumo nui a i ʻole wai nui)
• ʻUlaʻula, ʻulaʻula ʻili
• ʻO kaʻili pale a me ke kala bluish a puni nā maka
• Hoʻoikaika sweating
• Hōʻemi puʻuwai wikiwiki (tachycardia)

Hiki i nā pilikia o ka lolo a me nā ʻōnaehana hopohopo ke hoʻopili:

• Hiki ʻole ke hoʻolei i ka ʻai
• Ka nalowale o ka neʻe (lōlō) o nā hiʻupuʻu, nā wāwae, a me nā wāwae (nā ʻaoʻao lalo)
• Nā pilikia me ke kaulike
• ʻO ka neʻe ʻana o ka maka a i ʻole ka neʻe ʻana o ka wāwae a me nā wāwae (i kapa ʻia ʻo opsoclonus-myoclonus syndrome, a i ʻole "nā maka hulahula a me nā wāwae hulahula")

E nānā ka mea mālama ola i ke keiki. Kaukaʻi ʻia i ka wahi o ka tumo:

• Aia paha he puʻupuʻu a nui paha i loko o ka ʻōpū.
• E hoʻonui ʻia paha ke akepaʻa, inā ua palahalaha ka tumo i ke akepaʻa.
• Aia paha ke kiʻekiʻe o ke koko a me ka wikiwiki o ka puʻuwai inā aia ka tumo i kahi adrenal gland.
• Pehu paha nā aka Lymph.

Hana ʻia ka X-ray a i ʻole nā ​​hōʻike kiʻi ʻē aʻe e huli i ka tumo nui (mua) a ʻike i kahi i palahalaha ai. Pākuʻi ʻia kēia mau mea:

• ʻImi iwi
• Iwi-kukuna
• Pākuʻi x-ray
• CT scan o ka umauma a me ka ʻōpū
• MRI scan o ka umauma a me ka ʻōpū

Nā hoʻokolohua ʻē aʻe i hana ʻia e hoʻopili ʻia:

• ʻO Biopsy o ka tumo
• Biopsy iwi ʻōiwi
• Helu piha ke koko (CBC) e hōʻike nei i ka anemia a i ʻole nā ​​mea ʻē aʻe ʻē aʻe
• Ke aʻo ʻana i ka Coagulation a me ka helu sedimentation erythrocyte (ESR)
• Nā ho'āʻo Hormone (nā ho'āʻo koko e nānā i nā pae o nā hormones e like me catecholamines)
• MIBG scan (hōʻike kiʻi e hōʻoia i ke alo o neuroblastoma)
• ʻO ka hoʻāʻo 24 miki o ka mimi no catecholamines, homovanillic acid (HVA), a me vanillymandelic acid (VMA)

Ma muli o ka mālama ʻana:

• Kahi o ka tumo
• Ehia a kahi o ka palahalaha i pālahalaha ai
• Ka makahiki o ke kanaka

I kekahi mau hihia, ua lawa ka ʻoki ʻana. ʻO ka manawa pinepine, pono nō naʻe kekahi mau lāʻau ʻē aʻe. Hiki ke koi ʻia nā lāʻau anticancer (chemotherapy) inā pālahalaha ka tumo.Hiki ke hoʻohana ʻia ka radiation radiation.

Hoʻohana ʻia ka chemotherapy kiʻekiʻe, ka transplantation cell stem autologous, a me ka immunotherapy.

Hiki iā ʻoe ke hoʻomāmā i ke koʻikoʻi o ka maʻi ma ke komo ʻana i kahi hui kākoʻo maʻi ʻaʻai. ʻO ke kaʻana ʻana me nā poʻe ʻē aʻe i loaʻa nā ʻike a me nā pilikia maʻamau e hiki ke kōkua iā ʻoe a me kāu keiki e ʻike mehameha ʻole.

Kūleʻa ka hopena. I nā keiki ʻōpio loa, hele aku paha ka tumo iā ia iho, me ka mālama ʻole ʻia. A i ʻole, oʻo nā mākala o ka puʻupuʻu a ulu a lilo i puʻupuʻu non-cancerous (benign) i kapa ʻia he ganglioneuroma, hiki ke hemo ʻia me ka ʻoki kino. I nā hihia ʻē aʻe, pālahalaha koke ka tumo.

ʻOkoʻa ka pane i ka mālama ʻana. Kūleʻa pinepine ka mālama ʻana inā ʻaʻole pāhola ka maʻi ʻaʻai. Inā ua pālahalaha, ʻoi aku ka paʻakikī o ka neuroblastoma e hoʻōla. Hana maikaʻi nā keiki ʻōpio ma mua o nā keiki nui.

Hiki paha i nā keiki i mālama ʻia no neuroblastoma ke makaʻu i ka loaʻa ʻana o ka lua, ka maʻi ʻaʻai ʻokoʻa i ka wā e hiki mai ana.

Komo pū nā pilikia:

• Hoʻolahalaha (metastasis) o ka tumo
• Ka hōʻino a me ka nalo ʻana o ka hana o nā mea i hoʻopili ʻia

Kāhea i kāu mea hāʻawi inā loaʻa kāu keiki i nā ʻōuli o neuroblastoma. Hoʻomaikaʻi ka hōʻoia mua a me ka hoʻomaʻamaʻa i ka manawa o kahi hopena maikaʻi.

Kanesa - neuroblastoma

• ʻO Neuroblastoma i ke akepaʻa - CT scan

ʻO Dome JS, Rodriguez-Galindo C, Spunt SL, Santana VM. Nā Tumors paʻa pediatric. I: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. ʻO Oncology Clinical ʻo Abboff. 5th lā. Piladelapia, PA: Elsevier Saunders; 2014: chap 95.

Pūnaewele ʻo National Cancer Institute. Mālama ʻo Neuroblastoma (PDQ) - mana ʻoihana olakino. www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq. Hoʻohou i ʻAukake 17, 2018. Loaʻa iā Nowemapa 12, 2018.