ʻO hyperplasia Parathyroid

ʻO ka hyperplasia Parathyroid ka hoʻonui ʻana o nā gland parathyroid āpau. Aia nā aʻa parathyroid i ka ʻāʻī, kokoke a pili paha i ka ʻaoʻao hope o ka pona thyroid.

Kōkua nā palahalaha parathyroid e kāohi i ka hoʻohana ʻana o ka calcium i ke kino. Hana lākou i kēia ma ka hana ʻana i ka hormone parathyroid (PTH). Kōkua ʻo PTH i ka mālama ʻana i ka pae o ka calcium, phosphorus, a me ka wikamina D i loko o ke koko a he mea nui ia no nā iwi olakino.

Hiki i ka hyperplasia Parathyroid ke hana ʻia i ka poʻe me ka ʻole o ka moʻolelo ʻohana o ka maʻi, a i ʻole ma ke ʻano he ʻāpana o 3 hoʻoilina hoʻoilina hoʻoilina:

• Neoplasia endocrine maha I (MEN I)
• MEN IIA
• Hoʻokaʻawale ʻohana hyperparathyroidism

I ka poʻe me ka maʻi hoʻoilina i hoʻoili ʻia, hoʻohuli ʻia kahi moʻomeheu i loli i waena o ka ʻohana. Pono ʻoe e kiʻi i ka ʻāpana mai hoʻokahi makua e hoʻomohala i ke ʻano.

• I nā kāne I, pilikia nā pilikia ma nā parathyroid glands, a me nā tumors i ka pituitary gland a me ka pancreas.
• I MEN IIA, overactivity o ka parathyroid glands kū, me nā tumors i ka adrenal a thyroid gland.

ʻO ka hyperplasia Parathyroid ʻaʻole ia he ʻāpana o kahi maʻi hoʻoilina i ʻike pinepine ʻia. Kū ʻia ia ma muli o nā kūlana olakino ʻē aʻe. ʻO nā kūlana maʻamau i hiki ke kumu i ka hyperplasia parathyroid ka maʻi maʻi puʻuwai mau a me ka maʻi vitamona D mau. I nā kūlana ʻelua, hoʻonui ʻia nā ʻōpū parathyroid ma muli o ka haʻahaʻa o ka wikamina D a me nā pae calcium.

Pākuʻi ʻia paha nā ʻōuli:

• ʻO nā iwi iwi a ʻehaʻeha iwi paha
• Konipōpō
• Ka nele o ka ikehu
• ʻEha ʻeha
• Nusea

E hana ʻia nā hoʻokolohua koko e nānā i nā pae o:

• Kalipuna
• Pākuʻi
• Makanekiuma
• PTH
• Wikamina D
• Nā hana ʻino (Creatinine, BUN)

Hiki paha ke hana i kahi hōʻike mimi he 24 mau hola e hoʻoholo ai i ka nui o ka kānana e kānana ʻia mai ke kino i ka mimi.

Hiki i nā iwi x-ray a me ka hoʻāʻo ʻana o ka iwi (DXA) ke kōkua i ke ʻike ʻana i nā haki, ka nalo ʻana o ka iwi, a me ka palupalu ʻana o ka iwi. Hiki ke hana ʻia ka ultrasound a me ka CT scans e ʻike ai i nā ʻōpū parathyroid i ka ʻāʻī.

Inā ʻo parathyroid hyperplasia ma muli o ka maʻi o ka puʻupaʻa a i ʻole ka pae vitamin D haʻahaʻa a ʻike ʻia ia i kakahiaka nui, hiki i kāu mea hāʻawi ke noi iā ʻoe e ʻai i ka lāʻau D, nā lāʻau D-like me nā lāʻau.

Hana pinepine ʻia ke ʻoki ʻana ke hana nā Pathy parathyroid i nā PTH he nui a hana i nā ʻōuli. Lawe ʻia nā 3 1/2 glands. Hoʻokomo ʻia paha nā mea i koe i ka forearm a i ʻole ʻāʻī o ka ʻāʻī. ʻAe kēia i ke maʻalahi i ke aʻa inā hoʻi mai nā ʻōuli. Hoʻokomo ʻia kēia kiko e pale i ke kino mai ka liʻiliʻi o ka PTH, a hiki i ka hopena i nā pae calcium liʻiliʻi (mai ka hypoparathyroidism).

Ma hope o ke kahakaha ʻana, e hoʻomau a hoʻi paha ka pae calcium kiʻekiʻe. Hiki i ke kīpoki ke hana i kekahi manawa i ka hypoparathyroidism, kahi e hoʻohaʻahaʻa ai i ke kiʻekiʻe o ka calcium o ke koko.

Hiki i ka hyperplasia Parathyroid ke kumu i ka hyperparathyroidism, kahi e alakaʻi ai i ka hoʻonui ʻia o ka pae calcium i loko o ke koko.

Hoʻopili nā pilikia me ka hoʻonui ʻia o ka calcium i nā puʻupaʻa, kahi e hiki ai i nā pōhaku hakuʻala, a me ka osteitis fibrosa cystica (kahi palupalu, nāwaliwali i nā iwi).

Hiki i ke kīʻaha ke hōʻino i nā aʻalolo e kāohi ana i nā kaula leo. Hiki i kēia ke hoʻololi i ka ikaika o kou leo.

Hiki i nā pilikia ke hopena mai nā tumors ʻē aʻe nā ʻāpana o nā syndrome MEN.

Kāhea i kāu mea hāʻawi inā:

• Loaʻa iā ʻoe nā ʻōuli o hypercalcemia
• He moʻolelo ʻohana kāu no ka maʻi MEN

Inā loaʻa iā ʻoe kahi moʻolelo ʻohana o ka syndrome MEN, makemake paha ʻoe e loiloi i ka ʻikepili e nānā i ka ʻāpana hemahema. ʻO ka poʻe i loaʻa iā lākou ka ʻāpana kīnā e loaʻa i nā hoʻokolohua loiloi maʻamau e ʻike i nā ʻōuli mua.

Hoʻonui i nā gland parathyroid; Osteoporosis - parathyroid hyperplasia; ʻO ka lahilahi iwi - hyperplasia parathyroid; Osteopenia - parathyroid hyperplasia; ʻO ke kiʻekiʻe kiʻekiʻe o ka calcium - hyperplasia parathyroid; Maʻi maʻi ʻōniʻoniʻo - parathyroid hyperplasia; Hewa ʻiʻo - hyperplasia parathyroid; Overactive parathyroid - parathyroid hyperplasia

• Nānā Endocrine
• Nūʻau parathyroid

ʻO Reid LM, Kamani D, Randolph GW. Ka mālama ʻana i nā maʻi parathyroid. I: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Ke poʻo poʻo a me ka ʻāʻī. ʻEpekema 7 Piladelapia, PA: Elsevier; 2021: chap 123.

ʻO Thakker RV. ʻO nā gland parathyroid, hypercalcemia a me hypocalcemia. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 232.