ʻŌnaehana grading Gleason
ʻIke ʻia ka maʻi ʻaʻai Prostate ma hope o kahi biopsy. Lawe ʻia hoʻokahi a ʻoi paha nā kiko kiko mai ka prostate a nānā ʻia ma lalo o ka microscope.
ʻO ka ʻōnaehana grad Gleason e pili ana i ke ʻano o ka nānā ʻana o nā hunaola maʻi ʻaʻai prostate a pehea e hele ai a pālahalaha ai ka maʻi ʻaʻai. ʻO ka papa ʻo Gleason haʻahaʻa ʻoi aku ka lohi o ka ulu ʻana o ka maʻi ʻaʻai a ʻaʻole ikaika.
ʻO ka hana mua i ka hoʻoholo ʻana i ka papa Gleason e hoʻoholo i ka helu Gleason.
- Ke nānā nei i nā hunaola ma lalo o ka microscope, hāʻawi ke kauka i kahi helu (a i ʻole papa) i nā hunaola maʻi ʻaʻai prostate ma waena o 1 a me 5.
- Hoʻokumu ʻia kēia papa i ka ʻike ʻole ʻia o nā hunaola. ʻO ka papa 1 ʻo ia ke ʻano o nā hunaola e like me nā hunaola prostate maʻamau. ʻO ka grade 5 ka mea ʻokoʻa ke nānā aku o nā hunaola mai nā hunaola prostate maʻamau.
- Loaʻa i ka hapanui o nā maʻi ʻaʻai prostate nā hunaola i ʻokoʻa nā māka. No laila hoʻohana ʻia nā māka maʻamau ʻelua.
- Hoʻoholo ʻia ka helu Gleason ma o ka hoʻohui ʻana i nā māka maʻamau ʻelua. ʻO kahi laʻana, ʻo ka papa maʻamau o nā hunaola i kahi laʻana kikoʻī paha he pae 3, a ukali ʻia e nā huna hua ʻehā. ʻO ka helu Gleason no kēia hāpana he 7.
Hōʻike nā helu kiʻekiʻe i kahi kanesa ulu ulu ʻoi aku ka palahalaha.
I kēia manawa ka helu haʻahaʻa i hāʻawi ʻia i kahi tumo ka papa 3. Papa ma lalo o 3 hōʻike maʻamau i kokoke i nā hunaola maʻamau. Loaʻa ka helu Gleason ka hapa nui o nā maʻi ʻōlapa (ka helu o nā papa maʻa mau ʻelua) ma waena o 6 (nā helu Gleason o 3 + 3) a me 7 (nā helu Gleason o 3 + 4 a me 4 + 3).
I kekahi manawa, paʻakikī paha e wānana pehea e hana ai ka poʻe ma muli wale nō o kā lākou helu Gleason wale nō.
- ʻO kahi laʻana, hāʻawi ʻia paha kāu tumora i kahi helu Gleason o 7 inā ʻelua a ʻelima nā helu maʻamau ʻelua. Hiki mai ka 7 mai ka hoʻohui ʻana i ka 3 + 4 a i ʻole ka hoʻohui ʻana i ka 4 + 3.
- Ma ke ʻano holoʻokoʻa, ua ʻike ʻia kekahi me ka helu Gleason o 7 i loaʻa mai ka hoʻohui ʻana i ka 3 + 4 me ka maʻi ʻaʻai ʻoi loa ma mua o kekahi me ka helu Gleason o 7 e loaʻa mai ana mai ka hoʻohui ʻana iā 4 + 3. ʻO ia no ka mea me kahi 4 + 3 = Ua loaʻa i nā mākau 7 nā kaha ʻehā aʻe ma mua o nā huna 3. ʻOi aku ka maʻamau o nā huna o ka papa 4 a ʻoi aku paha ka palahalaha ma mua o ka pae 3 mau hunaola.
Ua hoʻokumu ʻia kahi ʻōnaehana pae pae hou 5. ʻO kēia ʻōnaehana kahi ala ʻoi aku ka maikaʻi e wehewehe ai i ka hopena o ka maʻi ʻaʻai a pane i ka lāʻau.
- Pūʻulu papa 1: helu Gleason 6 a ʻoi aku (ka maʻi ʻaʻai haʻahaʻa haʻahaʻa)
- Pūʻulu papa 2: helu Gleason 3 + 4 = 7 (ʻeleu pae waena)
- Pūʻulu papa 3: Gleason helu 4 + 3 = 7 (waena-papa maʻi ʻaʻai)
- Pūʻulu papa 4: Gleason helu 8 (kiʻekiʻe-papa maʻi 'aʻai)
- Pūʻulu papa 5: helu Gleason 9 a 10 (cancer high-grade)
Hōʻike kahi hui haʻahaʻa i kahi manawa kūpono no ka hoʻomaʻamaʻa kūleʻa ma mua o kahi hui kiʻekiʻe. ʻO ka manaʻo o ka hui kiʻekiʻe he ʻokoʻa ka nui o nā hunaola maʻi ʻaʻai mai nā hunaola maʻamau. ʻO ka manaʻo o kahi hui kiʻekiʻe ʻoi aku paha ka palahalaha ʻana o ka tumo.
Kōkua ka māka iā ʻoe a me kāu kauka e hoʻoholo i kāu koho lapaʻau, a me:
- ʻO ke kahua o ka maʻi ʻaʻai, e hōʻike ana i ka nui o ka palahalaha ʻana o ka maʻi ʻaʻai
- ʻO ka hopena hōʻike PSA
- ʻO kou olakino holoʻokoʻa
- ʻO kou makemake e loaʻa i ka ʻoki ʻana, radiation, a i ʻole nā lāʻau hormone, a ʻaʻohe lāʻau lapaʻau iki
Ka maʻi ʻaʻai Prostate - Gleason; Adenocarcinoma prostate - Gleason; Papa Gleason; Helu helu Gleason; Pūʻulu Gleason; Ka maʻi ʻaʻai Prostate - 5 pūʻulu papa
ʻO kertwick DG, Cheng L. Neoplasms o ka prostate. I: Cheng L, MacLennan GT, kertwick DG, eds. Pathology ʻoki lāʻau urologic. ʻEhā ed. Piladelapia, PA: Elsevier; 2020: chap 9.
Epstein JI. Pathology o ka neoplasia prostatic.I: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Piladelapia, PA: Elsevier; 2021: chap 151.
Pūnaewele ʻo National Cancer Institute. Hoʻomaʻo Prostate cancer (PDQ) - mana loea olakino. www.cancer.gov/types/prostate/hp/prostate-treatment-pdq#_2097_toc. Hoʻohou i Iulai 22, 2020. Loaʻa iā ʻAukake 10, 2020.
- Kanesa Prostate