ʻO ka hāʻawi manawale iwi

ʻO ka iwi iwi ka mea momona, momona ma loko o kou mau iwi. Loaʻa nā iwi o ka iwi iwi, i mau hunaola ʻole i lilo i mau huna koko.

ʻO nā kānaka me nā maʻi hoʻoweliweli i ke ola, e like me leukemia, lymphoma, a me myeloma hiki ke mālama ʻia me kahi transplant o ka iwi iwi. Kāhea pinepine ʻia kēia mea he transplant cell stem. No kēia ʻano lapaʻau, ʻohiʻohi ʻia ka iwi iwi mai kahi mea hāʻawi. I kekahi manawa, hiki i ka poʻe ke hāʻawi manawaleʻa i ko lākou iwi iwi.

Hiki ke hana ʻia ka hāʻawi iwi iwi ʻana ma o ka hōʻiliʻili ʻana paha i ka iwi o ka mea hāʻawi ma ke kauka, a i ʻole ma ka hemo ʻana i nā hunaola koʻokoʻo mai ke koko o ka mea hāʻawi.

ʻElua ʻano o ka hāʻawi iwi iwi:

• Ke kuʻi iwi ʻōiwi Autologous Aia ke hāʻawi nā kānaka i kā lākou iwi iwi ponoʻī. ʻO "Auto" ka manaʻo ponoʻī.
• Ka hoʻoneʻe iwi ʻōiwi Allogenic Aia ke hāʻawi a kekahi kanaka i ka momona o ka iwi. ʻO "Allo" kekahi ʻano ʻē aʻe.

Me kahi transplal allogenic, pono nā genes o ka mea hāʻawi i ka hapa liʻiliʻi e kūlike me nā ʻāpana o ka mea e loaʻa ana. ʻO ke kaikaina a kaikuahine paha he pāʻani maikaʻi. I kekahi manawa kūlike ʻole nā ​​mākua, nā keiki, a me nā ʻohana ʻē aʻe. Akā ma kahi o 30% o ka poʻe e pono ana i ka neʻe ʻana o ka iwi iwi hiki ke loaʻa i kahi mea hāʻawi manawaleʻa i ko lākou ʻohana ponoʻī.

ʻO ka 70% o ka poʻe ʻaʻohe o lākou hoahānau he hoʻokūkū maikaʻi paha e hiki ke loaʻa i hoʻokahi ma o ke kākau inoa ʻana o ka iwi iwi. Kapa ʻia ka mea nui loa ʻo Be the Match (bethematch.org). Kākau inoa ia i ka poʻe makemake e hāʻawi i ka iwi iwi a mālama i kā lākou ʻike i loko o kahi waihona. Hiki i nā kauka ke hoʻohana i ke keʻena hoʻopaʻa inoa e ʻike i kahi mea hāʻawi manawaleʻa no kahi kanaka e pono ai ka hoʻoneʻe iwi iwi.

Pehea e hui ai i kahi Registry Bone Marrow

I helu ʻia i loko o kahi registation donation bone marrow, pono kahi kanaka e:

• Ma waena o nā makahiki 18 a 60
• Healthy a hāpai ʻole

Hiki i nā kānaka ke hoʻopaʻa inoa ma ka pūnaewele a i ʻole ma kahi hoʻokau leka uila hāʻawi kūloko. ʻO nā mea ma waena o nā makahiki 45 a 60 e pono e hui pūnaewele. ʻAe ka poʻe kūloko kūlohelohe i nā mea kōkua i ʻōpio ma mua o ka makahiki 45. ʻO kā lākou mau hunaola ke kōkua i nā mea maʻi ma mua o nā pūnaeho kūmole mai ka poʻe kahiko.

Pono nā poʻe e hoʻopaʻa inoa:

• E hoʻohana i ka pulupulu e lawe i kahi laʻana o nā hunaola mai loko aʻe o ko lākou papalina
• Hāʻawi i kahi hāpana koko liʻiliʻi (e pili ana i ka punetune 1 a i ʻole 15 mau mililiter)

Hoʻomaʻo ʻia nā hunaola a i ʻole ke koko no nā protein ponoʻī, i kapa ʻia ʻo antigens kanaka leukosit (HLA). Kōkua ka HLA i kāu ʻōnaehana hakakā maʻi pale (pale pale) e haʻi i ka ʻokoʻa ma waena o nā kino o ke kino a me nā mea ʻaʻole mai kou kino ponoʻī.

ʻOi aku ka maikaʻi o nā transplant o ka iwi iwi inā nā HLA mai ka mea hāʻawi kālā a me ka mea maʻi ke kūlike. Inā kūlike maikaʻi nā HLA o kahi mea hāʻawi me kahi kanaka e pono ai kahi transplant, pono e hāʻawi ka mea hāʻawi i kahi hāpana koko hou e hōʻoia i ka pāʻani. A laila, hui pū kahi kākāʻōlelo me ka mea hāʻawi e kūkākūkā e pili ana i ke kaʻina hana hāʻawi iwi.

Hiki ke hōʻiliʻili ʻia nā pūnaewele Donor ma nā ʻano ʻelua.

ʻOhi hōʻiliʻili ke koʻokoʻo huna koko. Hōʻiliʻili ʻia ka hapa nui o nā hunaola ma o ke kaʻina i kapa ʻia ʻo leukapheresis.

• ʻO ka mea mua, hāʻawi ʻia ka mea hāʻawi i 5 mau lā o ke kī ʻana e kōkua i nā neʻe kūmole e neʻe mai ka iwi iwi i loko o ke koko.
• I ka hōʻiliʻili ʻana, hoʻoneʻe ʻia ke koko mai ka mea hāʻawi ma o kahi laina i kahi aa koko (IV). Hoʻokaʻawale ʻia ka ʻāpana o nā hunaola koko keʻokeʻo i loaʻa nā hunaola i loko o kahi mīkini a hemo e hāʻawi ʻia i ka mea loaʻa.
• Hoʻihoʻi ʻia nā hunaola ʻulaʻula i ka mea hāʻawi ma o ka IV i ka lima ʻē aʻe.

Loaʻa kēia hana i 3 mau hola. Nā hopena pili me:

• Poʻo poʻo poʻo
• Nā iwi ʻeha
• Hōʻoluʻolu mai nā nila i nā lima

ʻOhiʻohi iwi. Hana ʻia kēia ʻoki liʻiliʻi ma lalo o ka anesthesia ākea. ʻO kēia ka mea e hiamoe ka mea hāʻawi a ʻaʻohe ʻeha ma ke kaʻina hana. Lawe ʻia ka iwi iwi mai ka hope o kou mau iwi pelvic. Hoʻokahi hola paha ka hana.

Ma hope o ka ʻohi ʻana o ka iwi iwi, noho ka mea hāʻawi i ka haukapila a hiki i ko lākou ala piha ʻana a hiki ke ʻai a inu. Nā hopena pili me:

• Nusea
• ʻEha poʻo
• Ka luhi
• ʻEha a hōʻoluʻolu paha i ka hope haʻahaʻa

Hiki iā ʻoe ke hoʻomau i ka hana maʻamau ma kahi o hoʻokahi pule.

He kakaikahi loa nā pilikia no ka mea hāʻawi a ʻaʻohe hopena ola olakino. E pani ana kou kino i ka iwi iwi i hāʻawi ʻia ma kahi o 4 a 6 mau pule.

Ke kuʻi ʻana o ke koʻokoʻo kumu - manawaleʻa; Hāʻawi Allogeneic; Leukemia - hāʻawi manawale iwi; Lymphoma - hāʻawi manawale iwi; Myeloma - hāʻawi manawale iwi

Pūnaewele ʻAmelika Hui Pū ʻIa ʻAmelika. ʻO ke kanu ʻana o ke koʻokoʻo no ka maʻi ʻaʻai. www.cancer.org/treatment/treatments-and-side-effects/treatment-types/stem-cell-transplant.html. Loaʻa iā Nowemapa 3, 2020.

ʻO Fuchs E. Haploidentical hematopoietic cell transplantation. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds.Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 106.

Pūnaewele ʻo National Cancer Institute. ʻO nā transplants cell stem koko e hana ana i ke koko. www.cancer.gov/about-cancer/treatment/types/stem-cell-transplant/stem-cell-fact-sheet. Hoʻohou ʻia ʻAukake 12, 2013. Loaʻa iā Nowemapa 3, 2020.

• Ke kuʻi ʻana o ka iwi iwi
• Nā Pūʻulu Kumu