Ka nele V factor V

ʻO ka hemahema Factor V kahi maʻi hoʻokahe koko i hoʻoili ʻia i waena o nā ʻohana. Hoʻopili ia i ka hiki o ke koko ke kāpili.

ʻO ke kāpili koko kahi hana paʻakikī e pili ana i 20 mau protein ʻokoʻa i ka plasma koko. Kapa ʻia kēia mau proteins i nā kumu hoʻohui koko.

Hoʻokumu ʻia ka hemahema V ma muli o ka nele o ke kumu V. Ke haʻahaʻa a nalowale paha kekahi mau kumu o ke kāpili ʻana o ke koko, ʻaʻole huʻi pono kou koko.

Kākaʻikahi ka hemahema o ka ʻoihana V. E kumu ʻia e:

• Ua hele i lalo kahi ʻohana V hemahema i loko o nā ʻohana (hoʻoilina)
• Hoʻopilikia kahi antibody i ka hana V maʻamau maʻamau

Hiki iā ʻoe ke hoʻomōhala i kahi mea pale pale nāna e hoʻopilikia i ka mea V:

• Ma hope o ka hānau ʻana
• Ma hope o ka mālama ʻia ʻana me kekahi ʻano limu fibrin
• Ma hope o ke kaha ʻana
• Me nā maʻi autoimmune a me kekahi mau maʻi ʻaʻai

I kekahi manawa ʻaʻole maopopo ke kumu.

ʻAno like ka maʻi me ka hemophilia, koe wale ke kahe ʻana o ke kahe ʻana i nā hono. I ke ʻano hoʻoilina o ka hemahema o ka mea V, kahi moʻolelo ʻohana o ka maʻi koko he mea pilikia ia.

ʻO ke kahe nui ʻana me nā wā paʻipaʻi a ma hope o ka hānau hānau pinepine ʻana. Hiki i nā ʻōuli ʻē aʻe ke hoʻopili pū me:

• Kahe i ka ʻili
• Kahe ʻana o ka gum
• ʻĀpā nui loa
• Nā Nosebleeds
• Lōʻihi a ʻoi aku paha ka nui o ke kahe o ke koko me ke ʻoki a trauma paha
• Ke kahe nei ke kumu lāʻau Umbilical

ʻO nā hoʻāʻo e ʻike i ka hemahema o ka mea V:

• ʻO ke kumu V assay
• ʻO nā hoʻāʻo ʻana o ka hoʻopili ʻana i ke koko, me ka manawa thromboplastin hapa (PTT) a me ka manawa prothrombin
• Ka wā koko

Hāʻawi ʻia ʻoe i ka plasma koko hou a i ʻole nā ​​infusions plasma paʻahau hou i ka wā o ke kahe koko a i ʻole ma hope o ka ʻoki ʻana. Hoʻoponopono kēia mau hana i ka hemahema no kekahi manawa.

Maikaʻi ke kuanaʻike me ka hōʻailona a me ka lāʻau kūpono.

Hiki ke hana i ke kahe nui (hemorrhage).

E hele i ka lumi pilikia a kāhea paha iā 911 a i ʻole ka helu kūloko kūloko inā loaʻa iā ʻoe ka wehewehe ʻole a hoʻolōʻihi ʻia paha o ke koko.

Parahemophilia; Maʻi Owren; ʻO ka maʻi hōʻeha - nele V factor

• Hoʻomaʻamaʻa koko
• Huʻi koko

ʻO Gailani D, Wheeler AP, Neff AT. Nā hemahema coagulation ololi. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 137.

ʻO Ragni MV. Nā maʻi hemorrhagic: deficiencies factor coagulation. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 165.

ʻO Scott JP, Lolo VH. ʻO nā hemahema o ke kāpili hoʻoilina hoʻoilina. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 503.