Maʻi ʻo Von Willebrand

ʻO ka maʻi ʻo Von Willebrand ka maʻi hoʻokahe hoʻoilina hoʻoilina nui loa.

Hoʻokumu ʻia ka maʻi ʻo Von Willebrand e ka hemahema o ka von Willebrand factor. Kōkua ka mea Von Willebrand i ke kōkua ʻia o ka platelet koko a paʻa i ka paia o ke kīʻaha koko, he mea pono ia no ke kāpili ʻana i ke koko maʻamau. Aia kekahi mau ʻano o ka maʻi ʻo von Willebrand.

ʻO kahi moʻolelo ʻohana o kahi maʻi hoʻokahe ke kumu pilikia mua.

Pākuʻi ʻia paha nā ʻōuli:

• ʻO ke kahe menstrual maʻamau
• Kahe ʻana o ka gum
• ʻUpala
• Nā Nosebleeds
• ʻ Skinhū ʻili

Kaha: ʻO ka hapa nui o nā wahine me ke kahe nui a hoʻolōʻihi paha i ke kahe o ka menstrual ʻaʻole i loaʻa iā von Willebrand maʻi.

He paʻakikī paha ka maʻi ʻo Von Willebrand. ʻO nā pae haʻahaʻa von Willebrand a me nā kahe koko ʻaʻole mau ka manaʻo he maʻi ʻo Willebrand ʻoe.

Nā hoʻokolohua e hana ʻia ai e kuhikuhi pono i kēia maʻi ʻo:

• Ka wā koko
• Kikokiko kikokiko
• Pākuʻi VIII pae
• Nānā i ka hana platelet
• Heluna pāluna
• Hōʻike cofactor Ristocetin
• Nā hoʻokolohua kikoʻī Von Willebrand

Hoʻopili paha ka mālama me DDAVP (desamino-8-arginine vasopressin). He lāʻau ia e hāpai ai i ka pae factor von Willebrand a hoʻēmi i nā manawa no ke kahe ʻana o ke kahe.

Eia naʻe, ʻaʻole holo ka DDAVP no nā ʻano maʻi von Willebrand āpau. Pono e hoʻāʻo e hoʻoholo i ke ʻano o ka von Willebrand iā ʻoe. Inā ʻoe e hana ʻia i kahi ʻoki, hiki i kāu kauka ke hāʻawi iā ʻoe iā DDAVP ma mua o ke kaha ʻana e ʻike inā piʻi aʻe kāu von Willebrand factor factor.

ʻAe ʻia ka lāʻau Alphanate (antihemophilic factor) e hoʻēmi i ke kahe ʻana o ke koko i ka poʻe me ka maʻi e pono ai ke ʻoki a i ʻole nā ​​hana hoʻouka ʻē aʻe.

Hiki ke hoʻohana ʻia ka wai koko a i ʻole kekahi mau mea hoʻomākaukau VIII e hōʻemi i ke kahe ʻana o ke kahe.

Hiki ke hoʻemi i ke kahe ʻana i ka wā hāpai. ʻO nā wahine i loaʻa i kēia ʻano maʻamau ʻaʻohe o ke kahe nui i ka wā hānau hānau.

Ua hala kēia maʻi i loko o nā ʻohana. Hiki ke kōkua i ke aʻo ʻana genetic i nā mākua e hiki ke hoʻomaopopo i ka pilikia o kā lākou keiki.

Hiki ke hele i ke kahe ma hope o ke kaha ʻana a i ka wā i huki ʻia ai kahi niho.

Hiki i ka Aspirin a me nā lāʻau anti-inflammatory nonsteroidal ʻē aʻe (NSAIDs) ke hana i kēia ʻano maʻi. Mai lawe i kēia mau lāʻau me ka ʻole e kamaʻilio mua me kāu kauka olakino.

Kāhea i kāu mea hāʻawi inā kū ke kahe me ke kumu ʻole.

Inā loaʻa ʻoe i ka maʻi ʻo von Willebrand a ua hoʻonohonoho ʻia no ke kaha ʻana a i ʻole ma kahi ulia pōpilikia, e ʻike pono ʻoe a i ʻole kou ʻohana e haʻi i nā mea hāʻawi e pili ana i kāu ʻano.

ʻO ka maʻi maʻi maʻi - von Willebrand

• Hoʻomaʻamaʻa koko
• Huʻi koko

Kahawai VH, Scott JP. Maʻi ʻo Von Willebrand. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 504.

ʻO James P, Rydz N. Kūlana, biology, a me nā genetics o von Willebrand factor. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier; 2018: chap 138.

ʻO Neff AT. ʻO ka maʻi ʻo Von Willebrand a me nā hemorrhagic abnormalities o ka platelet a me ka vascular function. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 164.

ʻO Samuels P. Hematologic nā pilikia o ka hāpai keiki. I: Landon MB, Galan HL, Jauniaux ERM et al, eds. Nā Kāpena Gabbe: Nā Pregnancies Maʻamau a me nā Pilikia. 8th ed. Piladelapia, PA: Elsevier; 2021: chap 49.