Pheochromocytoma

ʻO Pheochromocytoma kahi tumo laha ʻole o ka ʻaʻa adrenal gland. ʻO nā hopena i ka hoʻokuʻu ʻia ʻana o ka epinephrine nui a me nā norepinephrine, nā hormones e kāohi i ka helu o ka naʻau, ka metabolism, a me ke kahe o ke koko.

Kū paha ʻo Pheochromocytoma ma ke ʻano he tumo hoʻokahi a i ʻole ʻoi aku ma mua o hoʻokahi ulu. Hoʻolālā maʻamau ia i waenakonu (medulla) o hoʻokahi a i ʻole nā ​​adrenal gland. ʻO nā glands adrenal ʻelua mau gland triangle-shaped. Aia kekahi gland ma luna o kēlā me kēia puʻupaʻa. I nā hihia kakaikahi, loaʻa kahi pheochromocytoma ma waho o ka adrenal gland. Ke hana ia, maʻa mau ia ma kahi ʻē aʻe i loko o ka ʻōpū.

He kakaikahi loa nā pheochromocytomas i maʻi ʻaʻai.

Hiki i nā tumors ke hana i kēlā me kēia makahiki, akā ʻike pinepine ʻia ia mai ka wā mua a waena o ka makua.

I kekahi mau manawa, ʻike ʻia ke ʻano i waena o nā lālā o ka ʻohana (hereditary).

ʻO ka hapanui o ka poʻe me kēia tumo e hōʻeha i kahi o nā ʻōuli, kahi e hana ai ke hoʻokuʻu ka tumo i nā homone. Kū mau nā hoʻouka mai kekahi mau minuke i nā hola. ʻO ke kaʻina o nā hōʻailona me:

• Poʻo poʻo poʻo
• Palpitations puʻuwai
• Hoʻoulu
• Piʻi koko kiʻekiʻe

Ke ulu nei ka tumo, hoʻonui pinepine nā hoʻouka i ke alapine, ka lōʻihi, a me ke koʻikoʻi.

ʻO nā ʻōuli ʻē aʻe e kū pū paha me:

• ʻEha o ka ʻōpū a i ʻole ka umauma
• Huhū, hopohopo
• Pallor
• Kaumaha emi
• ʻO Nusea a me ka luaʻi
• Pokole o ka hanu
• Ka hopu ʻana i nā maʻi
• Pilikia hiamoe

E hana ka mea mālama ola i kahi hoʻokolohua kino. E nīnau ʻia ʻoe e pili ana i kāu mōʻaukala olakino a me nā hōʻailona.

Hiki i nā hoʻokolohua i hana ʻia ke:

• Scanner CT ʻōpū
• ʻO Biopsy adrenal
• Catecholamines ke hoʻāʻo koko (serech catecholamines)
• Hōʻike Glucose
• Metanephrine hoʻokolohua koko (serum metanephrine)
• ʻO kahi hoʻokolohua kiʻi i kapa ʻia ʻo MIBG scintiscan
• MRI o ka ʻōpū
• ʻO nā catecholamines mimi
• Nā metanephrines mimi
• ʻIno PET o ka ʻōpū

Hoʻopili ka hana me ka wehe ʻana i ka tumo me ke ʻoki kino. He mea nui e hoʻokūpaʻa i kou kahe koko a me ka lāʻau iki me kekahi mau lāʻau ma mua o ke kaha. Pono ʻoe e noho i ka haukapila a nānā pono ʻia kāu mau hōʻailona koʻikoʻi a puni ka manawa o ke ʻoki. Ma hope o ke kahakaha ʻana, e nānā mau ʻia kāu mau hōʻailona koʻikoʻi i kahi keʻena mālama nui.

Ke hiki ʻole ke wehe ʻia i ka tumo, pono ʻoe e ʻai i ka lāʻau e hoʻokele ai. Pono ʻia kahi hui pū ʻana o nā lāʻau e kāohi i nā hopena o nā hormones keu. ʻAʻole maikaʻi ka radiation radiation a me ka chemotherapy i ka hoʻōla ʻana i kēia tumo.

ʻO ka hapanui o ka poʻe i loaʻa nā tumors noncancerous i wehe ʻia me ke ʻoki kino e ola nei ma hope o 5 mau makahiki. Hoʻi hou nā tumors i kekahi poʻe. ʻO nā pae o nā hormones norepinephrine a me epinephrine hoʻi i ka maʻamau ma hope o ke kaha ʻana.

Hiki ke hoʻomau i ke kahe koko kiʻekiʻe ma hope o ke kahakaha ʻana. Hiki i nā maʻamau maʻamau ke kaohi i ke kahe kiʻekiʻe.

ʻO ka poʻe i mālama kūleʻa ʻia no ka pheochromocytoma pono e hoʻokolohua i kēlā me kēia manawa e hōʻoia i ka hoʻi ʻole o ka tumo. Pōmaikaʻi paha nā lālā ʻohana pili mai ka hoʻāʻo ʻana, no ka mea, hoʻoilina kekahi mau hihia.

Kāhea i kāu mea hāʻawi inā ʻoe:

• Loaʻa nā ʻōuli o ka pheochromocytoma, e like me ka headache, sweating, a me nā palpitations
• Inā he pheochromocytoma i ka wā ma mua a hoʻi hou kāu mau ʻōuli

Nā Tumors Chromaffin; Paraganglionoma

• Nānā Endocrine
• Nā metastases Adrenal - CT scan
• Tumena Adrenal - CT
• Huna ka adrenal gland hormone

Pūnaewele ʻo National Cancer Institute. ʻO ka hoʻomaʻamaʻa Pheochromocytoma a me paraganglioma (PDQ) - mana ʻoihana olakino. Ka maʻi ʻaʻai.gov. www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_38_toc. Hoʻohou ʻia Kepakemapa 23, 2020. Loaʻa iā ʻOkakopa 14, 2020.

Pacak K, Timmers HJLM, Eisenhofer G. Pheochromocytoma. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 110.

Brigode WM, Miraflor EJ, Palmer BJA. Ka mālama ʻana o pheochromocytoma. I: Cameron AM, Cameron JL, eds. ʻO ke kaʻoki lāʻau lapaʻau o kēia manawa. 13th ed. Piladelapia, PA: Elsevier; 2020: 750-756.