Mea Kākau: Virginia Floyd
Lā O Ka Hana: 9 Aukake 2021
HōʻAno Hou I Ka Lā: 14 Nowemapa 2024
Anonim
Hepatocellular Carcinoma - Molecular Approaches to Treatment
Wikiō: Hepatocellular Carcinoma - Molecular Approaches to Treatment

ʻO ka Hepatocellular carcinoma ka maʻi ʻaʻai e hoʻomaka i ke ake.

ʻO ka Hepatocellular carcinoma ka nui o nā maʻi ʻaʻai ate. Kū pinepine pinepine kēia ʻano maʻi ʻaʻai i nā kāne ma mua o nā wahine. Hoʻomaopopo pinepine ʻia i nā makahiki 50 a ʻoi paha.

ʻAʻole like ka Hepatocellular carcinoma me ka maʻi ʻaʻai ate metastatic, e hoʻomaka ana i loko o kekahi okana (e like me ka umauma a i ʻole kolone) a pālahalaha i ke ake.

I ka hapanui o nā hihia, ke kumu o ka maʻi ʻaʻai ate he hōʻeha wā lōʻihi a scarring o ke ake (cirrhosis). Hoʻokumu ʻia ʻo Cirrhosis e:

  • ʻIno ʻino
  • Nā maʻi Autoimmune o ke ake
  • Hepatitis B a i ʻole hepatitis C mea hoʻomaʻi maʻi
  • ʻO ka hoʻohaunaele o ke ake e lōʻihi loa (mau loa)
  • ʻO ka nui o ka hao ma ke kino (hemochromatosis)

ʻO ka poʻe me ka maʻi hepatitis B a C paha ka makaʻu nui i ka maʻi ʻaʻai ate, ʻoiai inā ʻaʻole lākou e hoʻomohala i ka cirrhosis.

Hiki i nā ʻōuli o ke kanesa ate ke hoʻopili i kekahi o kēia mau mea:

  • ʻO ka ʻeha o ka ʻōpū a palupalu paha, ʻo ka ʻaoʻao ʻākau luna hoʻi
  • Māʻeha a hoʻokahe wale paha
  • Pahu hoʻonui ʻia (ascites)
  • ʻIli melemele a i ʻole nā ​​maka (jaundice)
  • ʻO ka pohō kaumaha i wehewehe ʻole ʻia

E hana ka mea mālama ola i kahi hoʻokolohua kino a nīnau e pili ana i kāu mau hōʻailona. Hōʻike ka hoʻokolohua kino i kahi ake nui, palupalu ke ake a i ʻole nā ​​hōʻailona ʻē aʻe o cirrhosis.


Inā manaʻo ka mea hāʻawi i ka maʻi ʻaʻai ate, nā mea i kauoha ʻia e kauoha ʻia e komo pū:

  • Scanner CT ʻōpū
  • Scanner MRI ʻōpū
  • ʻO ke ultrasound ʻōpū
  • ʻO ka biopsy ate
  • Nā hoʻāʻo hana ate
  • Serum alpha fetoprotein

ʻO kekahi poʻe i loaʻa ka manawa kūpono e hoʻomohala i ka maʻi ʻaʻai ate e loaʻa paha i nā hoʻokolohua koko maʻamau a me nā ultrasounds e ʻike ai ke ulu nei nā tumors.

E kuhikuhi pono i ka maʻi kanesa hepatocellular, pono e hana i kahi biopsy o ka tumo.

Pili ka mālama ʻana i ka holomua o ka maʻi ʻaʻai.

Hiki ke hana i ke kaha inā ʻaʻole hoʻolaha ʻia ka tumo. Ma mua o ke kaha ʻana, hiki ke mālama ʻia ka tumo me ka chemotherapy e hōʻemi i kona nui. Hana ʻia kēia i ka hāʻawi pololei ʻana i ka lāʻau i loko o ke akepaʻa me ka paipu (catheter) a i ʻole me ka hāʻawi ʻana iā ia i ke aniani (e IV).

Hiki ke kōkua i nā mālama uila i ka wahi o ka maʻi ʻaʻai.

ʻO ka Ablada kekahi ʻano hana i hiki ke hoʻohana ʻia. Ablate mea e luku ai. ʻO nā ʻano hana hoʻopau e pili ana i ka hoʻohana ʻana:

  • Nā nalu lekiō a i ʻole nā ​​ʻanuʻu uila
  • Ethanol (kahi waiʻona) a i ʻole acetic acid (winika)
  • Anuanu loa (cryoablation)

Paipai ʻia kahi transplant ate.


Inā ʻaʻole hiki ke wehe ʻia i ka maʻi ʻaʻai a pāhola paha i waho o ke ake, ʻaʻohe manawa maʻamau no ka hoʻōla wā lōʻihi. Hoʻomaopopo ka mālama ʻana ma ka hoʻomaikaʻi a hoʻonui i ke ola o ke kanaka. Hiki i ka mālama ʻana i kēia hihia ke hoʻohana i ka lāʻau hoʻomākaukau ʻia me nā lāʻau i hiki ke lawe ʻia e like me nā huaale. Hiki ke hoʻohana pū ʻia nā lāʻau hoʻomalu hou.

Hiki iā ʻoe ke hoʻomāmā i ke koʻikoʻi o ka maʻi ma ke komo ʻana i kahi hui kākoʻo maʻi ʻaʻai. ʻO ke kaʻana ʻana me nā poʻe ʻē aʻe i loaʻa nā ʻike a me nā pilikia maʻamau e hiki ke kōkua iā ʻoe e noʻonoʻo ʻole.

Inā hiki ʻole ke mālama loa ʻia ka maʻi ʻaʻai, make pinepine ka maʻi. Akā hiki ke loli ke ola, kaukaʻi ʻia i ka holomua o ka maʻi ʻaʻai ke ʻike ʻia a pehea ke kūleʻa ʻana o ka lāʻau.

Kāhea i kāu mea hāʻawi inā hoʻomōhala ʻoe i ka ʻeha mau o ka ʻōpū, keu hoʻi inā he mōʻaukala kou ma ke akepaʻa.

Pākuʻi ʻia nā ana Preventive:

  • ʻO ka pale ʻana ʻana a me ka mālama ʻana i ka maʻi hepatitis viral hiki ke kōkua i ka hōʻemi ʻana i kou makaʻi. Hiki i nā ʻōpio kamaliʻi ke kūʻē iā hepatitis B ke hōʻemi i ka makaʻu o ka maʻi ʻaʻai ate i ka wā e hiki mai ana.
  • Mai inu i ka nui o ka rama.
  • ʻO nā kānaka me kekahi ʻano o ka hemochromatosis (iron overload) pono e nānā ʻia no ka maʻi ʻaʻai ate.
  • ʻO ka poʻe i loaʻa ka maʻi hepitis B a i ʻole C a i ʻole cirrhosis paha e koi ʻia no ka loiloi ʻana i ka maʻi ʻaʻai ate.

ʻO ka maʻi puʻuwai ate mua loa; Tumor - ake; Kanesa - ake; Hepatoma


  • ʻŌnaehana Digestive
  • ʻO ka biopsy ate
  • Ka maʻi ʻaʻai Hepatocellular - CT scan

Abou-Alfa GK, Jarnagin W, Dika IE, et al. ʻO ke ake a me ka maʻi ʻaʻai bile. I: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. ʻO Oncology Clinical ʻo Abboff. ʻElua huaʻōlelo Piladelapia, PA: Elsevier; 2020: chap 77.

Di Bisceglie AM, Befeler AS. ʻO nā tumatic Hepatic a me nā cista. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi Liver: Pathophysiology / Diagnosis / Management. 10 o ka lā. Piladelapia, PA: Elsevier Saunders; 2016: chap 96.

Pūnaewele ʻo National Cancer Institute. ʻO ka mālama ʻana i ka maʻi ʻaʻa ʻōpio makua mua (PDQ) - mana ʻoihana olakino. www.kanes.gov/types/liver/hp/adult-liver-treatment-pdq. Hoʻohou ʻia Malaki 24, 2019. Loaʻa iā ʻAukake 27, 2019.

Pūnaewele Pūnaewele Manuahi Manuahi. Nā papa hana hoʻomaʻamaʻa maʻi NCCN i ka oncology: nā maʻi maʻi hepatobiliary. Mana 3.2019. www.nccn.org/professionals/physician_gls/pdf/hepatobiliary.pdf. Hoʻohou i ʻAukake 1, 2019. Loaʻa iā ʻAukake 27, 2019.

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