ʻO ka maʻi palahalaha hoʻohui

Anter

• He aha ka maʻi maʻi hoʻopili i hui ʻia?
• He aha nā hōʻailona?
• He aha ke kumu?
• Aia kekahi kumu pilikia?
• Pehea ia ʻike?
• Pehea e mālama ʻia ai?
• He aha ke kuanaʻike?

He aha ka maʻi maʻi hoʻopili i hui ʻia?

ʻO ka maʻi pilikino pili paʻa (MCTD) kahi maʻi autoimmune laha ʻole. Kāhea ʻia ia i kekahi manawa he maʻi overlap no ka mea ʻo ka hapanui o kāna mau ʻōuli ke kāwili ʻia me nā ʻano maʻi hoʻopili ʻē aʻe, e like me:

• ʻōnaehana lupus ʻōnaehana
• scleroderma
• polymyositis

ʻO kekahi mau hihia o ka MCTD kaʻana like i nā hōʻailona me ka rheumatoid arthritis.

ʻAʻohe lāʻau lapaʻau no MCTD, akā hiki ke mālama maʻamau ʻia me nā lāʻau a me nā loli nohona.

ʻOiai hiki i kēia maʻi ke hoʻololi i nā lālā like ʻole e like me ka ʻili, nā mākala, ka ʻōnaehana digestive a me nā akemāmā, a me kou mau hono, ua hoʻokau ʻia ka mālama ʻana e hoʻokele i nā wahi nui o ke komo ʻana.

Hiki ke hōʻike maʻalahi i ka hōʻike maʻi i ka waena a i ke koʻikoʻi, kaukaʻi ʻia i nā ʻōnaehana i pili.

Hiki ke hoʻohana mua ʻia nā mea hana laina e like me nonsteroidal anti-inflammatory agents, akā koi paha kekahi mau mea maʻi i ka hoʻomaʻamaʻa hou aʻe me ka lāʻau antimalarial hydroxychloroquine (Plaquenil) a i ʻole nā ​​mea hoʻoponopono hoʻololi i nā maʻi a me nā biologics.

Wahi a ka National Institutes of Health, ʻo ka helu ola 10 mau makahiki no ka poʻe me MCTD ma kahi o 80 pākēneka. ʻO ia hoʻi 80 mau pākēneka o ka poʻe me MCTD e ola nei 10 mau makahiki ma hope o ka ʻike ʻia.

He aha nā hōʻailona?

Hōʻike pinepine ʻia nā ʻōuli o MCTD ma ke kaʻina ma luna o kekahi mau makahiki, ʻaʻole i ka manawa hoʻokahi.

Ma kahi o 90 pākēneka o ka poʻe me MCTD i loaʻa ka hanana o Raynaud. ʻO kēia kahi ʻano i hōʻike ʻia e nā hoʻouka nui ʻana o ke anuanu, manamana manamana e lilo i polū, keʻokeʻo, a poni paha. Hana ʻia i kekahi manawa i mau mahina a i ʻole mau makahiki ma mua o nā ʻōuli ʻē aʻe.

Hoʻohālikelike nā hōʻailona hou aʻe o ka MCTD mai kēlā me kēia kanaka, akā ʻo kekahi o nā mea maʻamau e pili pū me:

• luhi
• fiva
• ʻeha ma nā ami maha
• hūwī
• pehu i nā hono
• nāwaliwali o nā mākala
• ke anuanu me ka loli o nā lima a me nā wāwae

ʻO nā hōʻailona kūpono ʻē aʻe e pili pū me:

• ʻeha ka umauma
• ʻōpū o ka ʻōpū
• reflux waikawa
• pilikia i ka hanu ʻana ma muli o ka hoʻonui ʻia o ke koko i nā akemā a me ka mumū o kaʻiʻo māmā
• paʻakikī a paʻa i nā ʻili o ka ʻili
• pehu nā lima

He aha ke kumu?

ʻAʻole ʻike ʻia ke kumu kūpono o MCTD. He maʻi autoimmune ia, ʻo ia hoʻi pili i kāu ʻōnaehana pale pale kuhi hewa i nā mea olakino olakino.

Kū ka MCTD ke hōʻeha kāu ʻōnaehana pale i nā pūnaewele hoʻopili e hāʻawi i ke kumu no nā lālā o kou kino.

Aia kekahi kumu pilikia?

ʻO kekahi poʻe me ka MCTD he moʻolelo ʻohana ko lākou, akā ʻaʻole i loaʻa i nā mea noiʻi kahi loulou moʻomeheu maopopo.

Wahi a ka Genetic and Rare Diseases Information Center (GARD), ʻoi aku ʻekolu mau manawa ka nui o nā wahine ma mua o nā kāne e hoʻomohala i kēia ʻano. Hiki iā ia ke hahau i kēlā me kēia makahiki, akā ʻo ka makahiki maʻamau o ka hoʻomaka ma waena o 15 a 25 mau makahiki.

Pehea ia ʻike?

Hiki i ka MCTD paʻakikī ke kuhikuhi ʻia no ka mea hiki ke like me nā ʻano he nui. Loaʻa paha iā ia nā hiʻohiʻona koʻikoʻi o scleroderma, lupus, myositis a i ʻole rheumatoid arthritis a i ʻole ka hui pū ʻana o kēia mau maʻi.

E hana i kahi kuhi, e hāʻawi ana kāu kauka iā ʻoe i kahi hoʻokolohua kino. E nīnau nō hoʻi lākou iā ʻoe no ka moʻolelo kikoʻī o kāu mau hōʻailona. Inā hiki, mālama i kahi lōkō o kāu mau ʻōuli, e hoʻomaopopo ana ke hiki a pehea ka lōʻihi o lākou. E kōkua kēia ʻike i kāu kauka.

Inā ʻike kāu kauka i nā hōʻailona olakino o MCTD, e like me ka pehu ʻana a puni nā hono, ka ʻāwīwī, a i ʻole ka hōʻike o ke anuanu, hiki iā lākou ke kauoha i kahi hoʻokolohua koko e nānā no kekahi mau mea ʻino e pili ana i ka MCTD, e like me anti-RNP, a me ke alo pū kekahi. o nā māka kuni.

Hiki paha iā lākou ke kauoha i nā hoʻokolohua e nānā no ke kū ʻana o nā lāʻau ʻino i pili loa ʻia me nā maʻi autoimmune e hōʻoia i ka hōʻoia pololei a / a i ʻole e hōʻoia i kahi maʻi overlap.

Pehea e mālama ʻia ai?

Hiki i ka lāʻau ke kōkua i ka mālama ʻana i nā ʻōuli o MCTD. Koi wale kekahi mau kānaka i ka mālama ʻana i ko lākou maʻi ke lele ke ahi, akā makemake paha kekahi i kahi lāʻau lōʻihi.

Hoʻohana ʻia nā lāʻau e mālama ai iā MCTD:

• Nā lāʻau anti-inflammatory Nonsteroidal (NSAIDs). Hiki i nā NSAID over-the-counter, e like me ibuprofen (Advil, Motrin) a me naproxen (Aleve), ke mālama i ka ʻeha pū a me ka mumū.
• Corticosteroids. Hiki i nā lāʻau Steroid, e like me prednisone, ke mālama i ka mumū a kōkua i ka hoʻōki ʻana i kāu ʻōnaehana pale maʻi mai ka hoʻouka kaua ʻana i nā mea olakino maikaʻi. Ma muli o ka hopena i nā hopena he nui, e like me ke kiʻekiʻe o ke koko, cataract, swings mood, a me ka loaʻa ʻana o ke kaumaha, hoʻohana mau ʻia lākou no nā manawa pōkole e hōʻalo i nā pilikia lōʻihi.
• Nā lāʻau Antimalarial. Hiki i ka Hydroxychloroquine (Plaquenil) ke kōkua me ka MCTD akahai a kōkua paha i ka pale ʻana i nā uila.
• Nā poloka ʻauana kalipuna. ʻO nā lāʻau e like me nifedipine (Procardia) a me amlodipine (Norvasc) kōkua i ka mālama ʻana i ka hanana o Raynaud.
• Nā Immunosuppressants. Pono paha ka MCTD nui loa i ka mālama lōʻihi me nā pale pale pale, he lāʻau ia e kāohi i kāu ʻōnaehana pale. ʻO nā laʻana maʻamau e pili ana iā azathioprine (Imuran, Azasan) a me mycophenolate mofetil (CellCept). Hiki ke kaupalena ʻia kēia mau lāʻau i ka wā o ka hāpai keiki ma muli o ka hiki no nā malformations fetal a i ʻole ka lāʻau ʻona.
• Nā lāʻau hypertension pulmonary. ʻO ke kiʻekiʻe o ka pulmonary ke kumu nui o ka make ma waena o ka poʻe me MCTD. Kauoha paha nā kauka i nā lāʻau e like me bosentan (Tracleer) a i ʻole sildenafil (Revatio, Viagra) e pale ai i ke kiʻekiʻe o ka pulmonary hypertension mai ka ʻino loa ʻana.

Ma waho aʻe o ka lāʻau lapaʻau, hiki i kekahi mau loli nohona ke kōkua:

• He aha ke kuanaʻike?

  ʻOiai ʻo ka laulaha o nā ʻōuli, hiki i ka MCTD ke hōʻike a noho maʻa mau i ka maʻi kaulike.

  Eia nō naʻe, holomua paha kekahi mau mea maʻi a hoʻomohala i nā hōʻike maʻi ʻoi loa e pili ana i nā mea nui e like me nā māmā.

  ʻO ka hapa nui o nā maʻi pilikino e manaʻo ʻia he mau maʻi multisystem a pono e ʻike ʻia e like me kēlā. ʻO ka nānā ʻana i nā mea nui ka ʻāpana nui o ka mālama olakino.

  I ka hihia o MCTD, pono e hoʻopili i kahi loiloi manawa o nā ʻōnaehana i nā ʻōuli a me nā hōʻailona e pili ana i:

  • SLE
  • polymyositis
  • scleroderma

  Ma muli o ka MCTD hiki ke loaʻa nā hiʻohiʻona o kēia mau maʻi, hiki i nā mea nui e like me nā akemāmā, ke ake, nā puʻupaʻa, a me ka lolo ke hoʻopili ʻia.

  E kamaʻilio me kāu kauka e pili ana i ka hoʻokumu ʻana i kahi hoʻolālā lōʻihi a me ka hoʻolālā hoʻokele e kūpono loa no kāu mau ʻōuli.

  Kōkua paha kahi kuhikuhi i kahi loea rheumatology ma muli o ka paʻakikī o kēia maʻi.