Mea Kākau: Judy Howell
Lā O Ka Hana: 1 Iulai 2021
HōʻAno Hou I Ka Lā: 14 Nowemapa 2024
Anonim
The Pathology of Lupus Nephritis and Lupus Podocytopathy- Part I
Wikiō: The Pathology of Lupus Nephritis and Lupus Podocytopathy- Part I

Anter

He aha ka lupus nephritis?

ʻO systemic lupus erythematosus (SLE) ka mea i kapa ʻia ʻo lupus. He kūlana ia e hoʻomaka ai ka pale ʻana o kāu ʻōnaehana pale i nā wahi like ʻole o kou kino.

ʻO ka Lupus nephritis kekahi o nā pilikia koʻikoʻi o ka lupus. Kū ʻia ia ke kumu ʻo SLE i kāu ʻōnaehana pale maʻi e hoʻouka i kou puʻupaʻa - kikoʻī, nā ʻāpana o kou puʻupaʻa e kānana i kou koko no nā huahana neoneo.

He aha nā hōʻailona o ka lupus nephritis?

ʻO nā maʻi Lupus nephritis e like me nā maʻi ʻino ʻē aʻe. Pākuʻi ʻia lākou:

  • mimi ʻeleʻele
  • ke koko i kou mimi
  • mimi hu
  • pono e mimi pinepine, keu hoʻi i ka pō
  • puffiness i nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae e pōʻino ana i ka holo o ka lā
  • ka loaʻa ʻana o ke kaupaona
  • kahe koko kiʻekiʻe

ʻIke i ka nephritis lupus

ʻO kekahi o nā hōʻailona mua o ka nephritis lupus ke koko i loko o kou mimi a i ʻole ka mimi mānoanoa.ʻO ke kiʻekiʻe o ke koko a me ka pehu ʻana i kou mau wāwae e hōʻike paha i ka nephritis lupus. Nā ho'āʻo e kōkua i kāu kauka e hana i kahi hōʻailona me kēia mau mea:


Nā hoʻāʻo koko

E nānā kāu kauka no nā pae kiʻekiʻe o nā huahana neoneo, e like me ka creatinine a me ka urea. ʻO ka maʻamau, kānana nā puʻupaʻa i kēia mau huahana.

Hōʻiliʻili mimi he 24 mau hola

Ana kēia ho'āʻo i ka hiki o ka hakuʻala e wae i nā ʻōpala. Hoʻoholo ia i ka nui o ka protein i loko o ka mimi ma mua o 24 mau hola.

Nā hoʻāʻo mimi

Ana ka mimi i ka hana o ka hakuʻala. Hoʻomaopopo lākou i nā pae o:

  • protein
  • ʻulaʻula koko
  • ʻili koko keʻokeʻo

Ke hoʻāʻo ʻana i ka ʻāpono Iothalamate

Hoʻohana kēia hoʻokolohua i ka pena kala e ʻike ai inā kānana kūpono kāu mau puʻupaʻa.

Hoʻokomo ʻia ka iothalamate radioactive i kou koko. A laila e hoʻāʻo kāu kauka i ka wikiwiki o ka lawe ʻia ʻana i loko o kāu mimi. Hiki paha iā lākou ke hōʻoia pololei i ka wikiwiki o ka haʻalele ʻana i kou koko. Kuhi ʻia kēia ʻo ka hōʻoia pololei loa o ka wikiwiki o ka kānana ʻana o ka hakuʻala.

ʻO Biopsy hakuʻala

ʻO Biopsies ke ala pololei loa a me ke ala hoʻi e hoʻouka e ʻike pono ai i nā maʻi puʻupaʻa. E hoʻokomo kāu kauka i kahi nila nui ma loko o kou ʻōpū a i loko o kou puʻupaʻa. Lawe lākou i kahi laʻana o nā puʻupaʻa e kālailai ʻia no nā hōʻailona o ka hōʻino.


Nā kahua o ka lupus nephritis

Ma hope o ka hōʻoia ʻana, e hoʻoholo ana kāu kauka i ke koʻikoʻi o kāu hōʻino puʻupaʻa.

Ua hoʻomohala ka World Health Organization (WHO) i kahi ʻōnaehana e hoʻokaʻawale i nā pae ʻelima o ka lupus nephritis i ka makahiki 1964. Ua hoʻokumu ʻia nā pae hoʻonohonoho hou i ka makahiki 2003 e ka International Society of Nephology and the Renal Pathology Society. Ua kāpae ka hōʻano hou i ka papa mua I i hōʻike ʻole ʻia o ka maʻi a ua hoʻohui ʻia i ka papa ʻeono:

  • Papa I: Minimal mesangial lupus nephritis
  • Papa II: Mesangial proliferative lupus nephritis
  • Papa III: nephritis lupus kikoʻī (ʻeleu a hoʻomau, hoʻonui a me sclerosing)
  • Papa IV: Diffuse lupus nephritis (ʻeleu a hoʻomau, hoʻonui a me sclerosing, segmental a me global)
  • Papa V: Membranous lupus nephritis
  • Papa VI: Advanced sclerosis lupus nephritis

Nā koho lapaʻau no ka lupus nephritis

ʻAʻohe lāʻau lapaʻau no ka nephritis lupus. ʻO ka pahuhopu o ka mālama ʻana e mālama i ka pilikia mai ka ʻino loa ʻana. Hiki ke pale i ka hōʻino ʻana o ka hakuʻala i ka wā mua ke pale i ka pono no kahi transplan kidney.


Hiki i ke olakino ke hāʻawi i ke kōkua mai nā ʻōuli lupus.

ʻO nā mālama maʻamau e:

  • hoʻoliʻiliʻi i kāu lawe ʻana i ka protein a me ka paʻakai
  • ka lawe ʻana i ka lāʻau no ke kaomi koko
  • e hoʻohana ana i nā steroid e like me prednisone (Rayos) e hoʻēmi i ka pehu a me ka mumū
  • lawe i nā lāʻau e kāohi i kou ʻōnaehana pale e like me cyclophosphamide a i ʻole mycophenolate-mofetil (CellCept)

Hāʻawi ʻia ka noʻonoʻo kūikawā i nā keiki a i nā wahine hāpai paha.

Pono paha ka hōʻino ākea ākea i kahi lāʻau hou aʻe.

Nā pilikia o ka nephritis lupus

ʻO ka pōpilikia koʻikoʻi e pili pū ana me ka nephritis lupus ka hoʻokō ʻole o ka hakuʻala. ʻO ka poʻe me ke kīnā ʻole o ka puʻuwai e pono ai i kahi dialysis a i ʻole kahi transplant kidney.

ʻO Dialysis ka mea koho mua loa no ka mālama ʻana, akā ʻaʻole ia e holo a mau loa. ʻO ka hapa nui o nā mea maʻi dialysis e pono ai kahi transplant. Eia nō naʻe, hala paha he mau mahina a mau makahiki paha ma mua o ka loaʻa ʻana o kahi mea hāʻawi.

ʻO ka nānā wā lōʻihi no ka poʻe me ka nephritis lupus

ʻOkoʻa ka nānā no ka poʻe me ka nephritis lupus. ʻIke ka hapa nui o nā poʻe i nā ʻōuli intermittent wale nō. ʻIke wale ʻia kā lākou hōʻino kīhāpai i ka wā o nā hoʻokolohua mimi.

Inā loaʻa iā ʻoe nā hōʻailona nephritis koʻikoʻi hou aʻe, aia ʻoe i ka nui o ka makaʻu no ka nalo ʻana o ka hana hakuʻala. Hiki ke hoʻohana i nā mālama ʻana e hoʻolohi i ka papa o ka nephritis, akā ʻaʻole kūleʻa mau lākou. E kamaʻilio me kāu kauka e pili ana i kahi kūpono e kūpono iā ʻoe.

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