Ka hoʻomaopopo ʻana i nā mālama Infusion no Multiple Sclerosis

Anter

• Q&A: Ke lawelawe nei i nā hoʻoponopono infusion
• Q:
• A:
• Nā lāʻau lapaʻau hoʻōla Infusion
• Alemtuzumab (Lemtrada)
• Natalizumab (Tysabri)
• Mitoxantrone hydrochloride
• ʻO Ocrelizumab (Ocrevus)
• Nā hopena ʻaoʻao o ke kaʻina infusion
• Nā hopena ʻē aʻe o nā lāʻau hoʻowahāwahā
• Alemtuzumab
• Natalizumab
• Mitoxantrone hydrochloride
• Ocrelizumab
• E kamaʻilio me kāu kauka

Ke mālama nei i nā sclerosis he nui (MS)

ʻO ka sclerosis Multiple (MS) kahi maʻi autoimmune e hoʻopili i ka ʻōnaehana waena (CNS).

Me MS, hōʻewa hewa kāu ʻōnaehana pale i kou aʻa a luku i ka myelin, ko lākou pale pale. Inā haʻalele ʻole ʻia, hiki iā MS ke luku i nā myelin āpau e pili ana i kou aʻa. A laila hoʻomaka paha ia e hōʻeha i nā aʻalolo iā lākou iho.

ʻAʻohe mea ola no MS, akā nui nā ʻano o ka mālama ʻana. I kekahi mau hihia, hiki i ka lapaʻau ke hoʻolohi i ka wikiwiki o MS. Hiki ke kōkua i ka hoʻomaʻamaʻa e hōʻoluʻolu i nā hōʻailona a hoʻemi i ka hōʻino hiki ke hana ʻia e MS flare-ups. ʻO nā lapalapa ahi nā wā ke loaʻa iā ʻoe nā hōʻailona.

Eia nō naʻe, i ka manawa i hoʻomaka ai kahi hoʻouka kaua, pono paha ʻoe i kahi ʻano lāʻau ʻē aʻe i kapa ʻia he mea hoʻololi maʻi. Hiki i nā mea hoʻololi maʻi ke hoʻololi i ka ʻano o ka maʻi. Hiki iā lākou ke kōkua i ka lohi o ka holomua o MS a hoʻēmi i nā uila.

ʻO kekahi mau hoʻoponopono hoʻoponopono hoʻololi e like me nā lāʻau i hoʻokomo ʻia. He kōkua nui paha kēia mau lāʻau hoʻohuihui i ka poʻe me MS kūpikipiki a holomua paha. E heluhelu e aʻo hou e pili ana i kēia mau lāʻau a pehea e kōkua ai iā lākou e mālama iā MS.

Q&A: Ke lawelawe nei i nā hoʻoponopono infusion

Q:

Pehea e hāʻawi ʻia ai nā hana hoʻoweliweli?

A:

Hoʻokomo pinepine ʻia kēia mau lāʻau. ʻO kēia ke loaʻa iā ʻoe iā lākou ma o kou aa. Eia naʻe, ʻaʻole ʻoe e hoʻokomo i kēia mau lāʻau iā ʻoe iho. Hiki iā ʻoe ke loaʻa wale i kēia mau lāʻau mai kahi lawelawe mālama ola i kahi wahi olakino.

Nā lāʻau lapaʻau hoʻōla Infusion

I kēia lā ʻehā mau lāʻau lapaʻau infusible i loaʻa e mālama iā MS.

Alemtuzumab (Lemtrada)

Hāʻawi nā kauka iā alemtuzumab (Lemtrada) i ka poʻe i pane maikaʻi ʻole i ʻelua mau lāʻau MS ʻē aʻe.

Ke hana nei kēia lāʻau lapaʻau ma ka hoʻoliʻiliʻi lohi ʻana i ka helu o kou kino o T a me B lymphocytes, ʻo ia nā ʻano o nā hunaola keokeo (WBCs). Hiki i kēia hana ke hōʻemi i ka mumū a me ka hōʻino ʻana i nā hunaola nerve.

Loaʻa iā ʻoe kēia lāʻau i hoʻokahi manawa i kēlā me kēia lā no nā lā ʻelima. A laila hoʻokahi makahiki ma hope o kāu mālama mua ʻana, loaʻa iā ʻoe ka lāʻau i hoʻokahi manawa i kēlā me kēia lā no nā lā ʻekolu.

Natalizumab (Tysabri)

Hana ʻo Natalizumab (Tysabri) ma ka hoʻōki ʻana i nā hunaola ʻinoʻino mai ke komo ʻana i kou lolo a me ka iwi kuamoo. Loaʻa iā ʻoe kēia lāʻau i hoʻokahi manawa i kēlā me kēia ʻehā pule.

Mitoxantrone hydrochloride

ʻO Mitoxantrone hydrochloride kahi lapaʻau infusion MS a me kahi lāʻau chemotherapy i hoʻohana ʻia e mālama ai i ka maʻi ʻaʻai.

Hiki maikaʻi ke hana no nā poʻe me MS holomua (SPMS) a i ʻole MS hōʻino wikiwiki. ʻO ia no ka mea he pale pale pale ia, ʻo ia hoʻi he hana ia e hoʻopau i ka hopena o kāu ʻōnaehana pale pale i nā hoʻouka MS. Hiki i kēia hopena ke hōʻemi i nā ʻōuli o kahi MS flare-up.

Loaʻa iā ʻoe kēia lāʻau i hoʻokahi manawa i kēlā me kēia ʻekolu mau mahina no ke koina cumulative maximum loa (140 mg / m²) e loaʻa paha i loko o ʻelua a ʻekolu paha makahiki. Ma muli o ka hopena o nā hopena koʻikoʻi, hōʻike wale ʻia ia no ka poʻe me MS koʻikoʻi.

ʻO Ocrelizumab (Ocrevus)

ʻO Ocrelizumab ka lapaʻau infusion hou loa no MS. Ua ʻae ʻia e ka Food and Drug Administration (FDA) ma 2017.

Hoʻohana ʻia ʻo Ocrelizumab e mālama i ka hoʻi hou ʻana a i ʻole nā ​​ʻano holomua mua o MS. ʻO ka ʻoiaʻiʻo, ʻo ia ka lāʻau mua i ʻae ʻia e mālama i ka MS holomua mua (PPMS).

Manaʻo ʻia kēia lāʻau lapaʻau e hana ʻia ma ke kālele ʻana i nā lymphocytes B nona ke kuleana no ka pohō a me ka hoʻoponopono ʻana o ka myelin sheath.

Hāʻawi ʻia ia i loko o nā infusions 300-milligram, hoʻokaʻawale ʻia e ʻelua pule. Ma hope o kēlā, hāʻawi ʻia i nā infusions 600-milligram i kēlā me kēia ʻeono mau mahina.

Nā hopena ʻaoʻao o ke kaʻina infusion

Hiki i ke kaʻina infusion ke hana i nā hopena ʻaoʻao, i hiki ke hoʻopili ʻia:

• paopao a i ʻole ke kahe ʻana i ka paepae injection
• ka pīpī, a i ka ʻulaʻula a me ka hoʻomehana ʻana o kou ʻili
• haʻalulu
• nausea

Hiki iā ʻoe ke loaʻa kahi hopena infusion. ʻO kēia kahi hopena lāʻau i kou ʻili.

No kēia mau lāʻau āpau, hiki ke hana i kahi hopena infusion i loko o nā hola mua ʻelua o ka hoʻokele, akā hiki ke hana i kahi hopena a 24 mau hola ma hope. Hiki i nā ʻōuli ke hoʻohui pū:

• hives
• pākuʻi scaly ma kou ʻili
• mehana a i ʻole kuni
• hūwī

Nā hopena ʻē aʻe o nā lāʻau hoʻowahāwahā

Loaʻa i kēlā me kēia lāʻau i hoʻokomo ʻia i nā hopena ʻaoʻao ponoʻī.

Alemtuzumab

Hiki i nā hopena ʻaoʻao maʻamau o kēia lāʻau ke komo pū:

• hūwī
• ʻeha poʻo
• fiva
• anu anu
• nausea
• maʻi urinary tract maʻiʻaʻai (UTI)
• luhi

Hiki i kēia lāʻau ke kumu i nā hopena koʻikoʻi loa, a me nā hopena make paha. Hiki iā lākou ke hoʻopili:

• nā hopena autoimmune, e like me ka maʻi ʻo Guillain-Barré a me ka maikaʻi ʻole o ka ʻōpū
• maʻi ʻaʻai
• nā maʻi koko

Natalizumab

Hiki i nā hopena ʻaoʻao maʻamau o kēia lāʻau ke komo pū:

• nā maʻi maʻi
• hopena maʻi ʻaʻai
• ʻeha poʻo
• luhi
• kaumaha

Hiki i nā hopena ʻē aʻe ke hoʻopili i:

• kahi maʻi lolo laha a make hoʻi i kapa ʻia ʻo leukoencephalopathy multifocal holomua (PML)
• nā pilikia o ke ake, me nā ʻōuli e like me:
  • ka melemele o kou ʻili a i ʻole ke keʻokeʻo o kou mau maka
  • mimi ʻeleʻele a ʻeleʻele (ti-kala)
  • ʻeha ma kaʻaoʻao ʻākau o luna o kou ʻōpū
  • ke kahe ʻana a i ʻole ka palapū e ʻoi aku ka maʻalahi ma mua o ka maʻamau
  • luhi

Mitoxantrone hydrochloride

Hiki i nā hopena ʻaoʻao maʻamau o kēia lāʻau ke komo pū:

• nā pae WBC haʻahaʻa, i hoʻonui ai i kou makaʻi i nā maʻi
• kaumaha
• ʻeha iwi
• nausea a luaʻi paha
• poho lauoho
• UTI
• amenorrhea, a i ʻole ka hapa ʻole o ka manawa menstrual

Hiki i nā hopena ʻē aʻe ke hoʻopili i:

• kūleʻa puʻuwai congestive (CHF)
• hakuʻala ʻole

ʻO ka loaʻa ʻana o ka nui o kēia lāʻau lapaʻau iā ʻoe i ka hopena o nā hopena ʻaoʻao i hiki ke lilo i mea ʻawahia loa i kou kino, no laila e hoʻohana wale ʻia ka mitoxantrone i nā hihia MS koʻikoʻi. Hoʻopili kēia i ka CHF, nā kōpaʻa ʻole, a i ʻole nā ​​pilikia koko. E nānā pono kāu kauka iā ʻoe no nā hōʻailona o nā hopena i ka wā o ka mālama ʻana me kēia lāʻau.

Ocrelizumab

Hiki i nā hopena ʻaoʻao maʻamau o kēia lāʻau ke komo pū:

• nā maʻi maʻi
• nā hopena infusion

Hiki i nā hopena ʻē aʻe ke hoʻopili i:

• PML
• reactivation o hepatitis B a i ʻole shingles, inā lākou i loko o kāu ʻōnaehana
• ʻōnaehana pale nawaliwali
• maʻi ʻaʻai, me ka maʻi ʻaʻai umauma

I kekahi mau hihia, hiki i kāu kauka ke ʻōlelo aku i nā hoʻoponopono infusion ʻē aʻe. Hoʻohana ʻia paha kēia mau lāʻau e mālama ai i ka hoʻi hou ʻana i pane ʻole i nā corticosteroids. Hoʻopili lākou i ka plasmapheresis, e pili ana i ka lawe ʻana i ke koko mai kou kino, ka kānana ʻana iā ia e hemo i nā mea ʻino e hoʻouka nei i kāu ʻōnaehana, a hoʻihoʻi i ke koko "hoʻomaʻemaʻe" i kou kino ma o kahi transfusion. Hoʻopili pū lākou i ka immunoglobulin intravenous (IVIG), kahi kuʻi e kōkua e hoʻonui i kāu ʻōnaehana pale.

E kamaʻilio me kāu kauka

Hiki i nā lapaʻau infusion ke koho maikaʻi e kōkua i ka mālama ʻana i nā ʻōuli MS a me nā mumū. Eia naʻe, ʻaʻole kūpono kēia mau lāʻau no kēlā me kēia. Hāpai lākou i nā pilikia o nā pilikia akā akā koʻikoʻi. Eia nō naʻe, he nui ka poʻe i ʻike he kōkua.

Inā loaʻa iā ʻoe kahi MS holomua a ʻimi paha i kahi ala ʻoi aku ka maikaʻi e kāohi ai i kāu mau ʻōuli, e nīnau i kāu kauka e pili ana i nā hoʻomaʻemaʻe infusion Hiki iā lākou ke kōkua iā ʻoe e hoʻoholo inā he koho maikaʻi paha kēia mau lāʻau iā ʻoe.