Immunotherapy ma ke ʻano he laina laina lua no ka maʻi ʻaʻai liʻiliʻi liʻiliʻi liʻiliʻi
Anter
- Immunotherapy: Pehea e hana ai
- Nā mea hoʻopuka helu kaha Checkpoint no NSCLC
- Āhea ʻoe e loaʻa ai i ka maʻi pale maʻi?
- Pehea ʻoe e loaʻa ai i ka immunotherapy?
- Pehea ka maikaʻi o kā lākou hana?
- He aha nā hopena?
- Lawe aku
Ma hope o kou ʻike ʻia me ka maʻi ʻaʻai liʻiliʻi liʻiliʻi liʻiliʻi (NSCLC), e hele pū ana kāu kauka me kāu mau koho lapaʻau me ʻoe. Inā loaʻa ʻoe i ka maʻi ʻaʻa mua, ʻo ke koho ke koho mua mua. Inā holomua kou maʻi ʻaʻai, e mālama kāu kauka iā ia me ke kahakaha, chemotherapy, radiation, a i ʻole ka hui pū ʻana o nā mea ʻekolu.
Hiki i ka Immunotherapy ke hana i ka lālani lua no NSCL. ʻO ke kumu kēia he moho paha ʻoe no ka immunotherapy inā ʻaʻole holo pono ka lāʻau mua āu e hoʻāʻo ai a oki paha i ka hana.
I kekahi manawa hoʻohana nā kauka i ka immunotherapy ma ke ʻano he lālani mua me nā lāʻau ʻē aʻe i nā maʻi ʻino hope i pāhola ʻia i loko o ke kino.
Immunotherapy: Pehea e hana ai
Hana ka Immunotherapy i ka hoʻonāukiuki ʻana i kāu ʻōnaehana pale e ʻike a pepehi i nā hunaola maʻi ʻaʻai. ʻO nā lāʻau lapaʻau immunotherapy i hoʻohana ʻia e mālama iā NSCLC i kapa ʻia nā checkpoint inhibitors.
He pūʻali koa o kāu ʻōnaehana pale o nā hunaola i kapa ʻia nā pūnaewele T, nāna e ʻimi i ka maʻi ʻaʻai a me nā huna haole weliweli ʻē aʻe a luku iā lākou. ʻO nā checkpoints nā protein i ka ʻili o nā hunaola. Hoʻomaopopo lākou i nā hunaola T inā he ʻoluʻolu a hoʻopōʻino paha kahi pūnaewele. Pale nā checkpoints i nā hunaola olakino ma ka pale ʻana i kāu ʻōnaehana pale pale mai ka hoʻouka kaua ʻana iā lākou.
Hiki i nā hunaola maʻi ʻaʻai ke hoʻohana i kēia mau wahi nānā e peʻe ai mai ka pale pale. Pale nā mea kāohi checkpoint i nā protein i hiki ai i nā hunaola T ke ʻike i nā hunaola maʻi ʻino a luku iā lākou. ʻO ke kumu, hana kēia mau lāʻau i ka wehe ʻana i nā paleki ma ka pane o ka ʻōnaehana pale pale kūʻē.
Nā mea hoʻopuka helu kaha Checkpoint no NSCLC
Mālama nā lāʻau lapaʻau ʻehā i ka NSCLC:
- Nivolumab (Opdivo) a me pembrolizumab (Keytruda)
ālai i kahi protein i kapa ʻia PD-1 ma ka ʻili o nā pūnaewele T. Pale ʻo PD-1 i nā hunaola T
mai ka hōʻeha ʻana i ka maʻi ʻaʻai. ʻO ka pale ʻana iā PD-1 ʻae i ka ʻōnaehana pale i ke alualu i lalo
a luku i nā hunaola maʻi ʻaʻai. - Atezolizumab (Tecentriq) a me durvalumab
(Imfinzi) ālai i kahi protein ʻē aʻe i kapa ʻia PD-L1 ma ka ʻili o nā hunaola puʻupuʻu a
nā hunaola ʻili. Hoʻopuka pū ka pale ʻana i kēia protein i ka pane ʻōnaehana kūʻē iā
ka maʻi ʻaʻai.
Āhea ʻoe e loaʻa ai i ka maʻi pale maʻi?
Hoʻohana nā kauka iā Opdivo, Keytruda, a me Tecentriq ma ke ʻano he laina laina lua. E loaʻa paha iā ʻoe kekahi o kēia mau lāʻau inā ua hoʻomaka hou kou kanesa e ulu hou ma hope o ka chemotherapy a i ʻole kahi lāʻau ʻē aʻe. Hāʻawi ʻia ʻo Keytruda i kahi lālani mua no NSCLC pae hope, me ka chemotherapy.
ʻO Imfinzi no ka poʻe me ka pae 3 NSCLC i hiki ʻole ke ʻoki poepoe, akā ʻo ko lākou maʻi ʻaʻai ʻaʻole i ʻoi aku ka maikaʻi ma hope o ka chemotherapy a me ka radiation. Kōkua ia i ka hōʻoki ʻana i ka maʻi ʻaʻai mai ka ulu ʻana a hiki i ka hiki.
Pehea ʻoe e loaʻa ai i ka immunotherapy?
Hāʻawi ʻia nā lāʻau Immunotherapy ma ke ʻano he infusion ma o kahi aa i loko o kou lima. E loaʻa iā ʻoe kēia mau lāʻau i hoʻokahi manawa i kēlā me kēia ʻelua a i ʻekolu pule paha.
Pehea ka maikaʻi o kā lākou hana?
Ua ʻike kekahi poʻe i nā hopena koʻikoʻi mai nā lāʻau immunotherapy. Ua hōʻemi ka lāʻau i ko lākou puʻupuʻu, a ua hooki ia i ka maʻi ʻaʻai mai ka ulu ʻana no nā mahina he nui.
Akā ʻaʻole ka poʻe āpau e pane i kēia lapaʻau. Kū paha ka maʻi ʻaʻai no kekahi manawa, a laila hoʻi. Ke hoʻāʻo nei nā mea noiʻi e aʻo i nā ʻōpala e pane maikaʻi i ka pale maʻi immunotherapy, no laila hiki iā lākou ke hoʻokau i kēia hana i ka poʻe e loaʻa ka pōmaikaʻi nui loa mai ia ia.
He aha nā hopena?
Nā hopena ʻaoʻao āpau mai nā lāʻau immunotherapy i:
- luhi
- ʻūhā
- nausea
- ʻūlili
- hūwī
- poho ʻai
- kōpaʻa
- pāhoehoe
- ʻeha pū
ʻAʻohe laha nā hopena ʻino ʻoi aʻe. Ma muli o ka hoʻomāhuahua ʻana o kēia mau lāʻau i ka pane o ke kūlohelohe, hiki i ka ʻōnaehana pale ke hoʻouka i ka hoʻouka kaua i nā mea ʻē aʻe e like me nā akemāmā, nā puʻupaʻa, a me ke ake. He koʻikoʻi paha kēia.
Lawe aku
ʻAʻole ʻike pinepine ʻia ʻo NSCLC a hiki i ka hopena o ka hopena, e paʻakikī ana e mālama me ke ʻoki ʻana, chemotherapy, a me radiation. Ua hoʻomaikaʻi ʻo Immunotherapy i ka mālama ʻana i kēia maʻi ʻaʻai.
Kōkua nā lāʻau lapaʻau hōʻoki Checkpoint i ka lohi o ka ulu ʻana o NSCLC i pālahalaha aʻe. ʻAʻole holo pono kēia mau lāʻau no kēlā me kēia kanaka, akā hiki iā lākou ke kōkua i kekahi poʻe me ka hopena o ka pae NSCLC e hele i ke kala ʻana a ola lōʻihi.
Ke aʻo nei nā kānaka noiʻi i nā lāʻau immunotherapy hou i nā hoʻokolohua hoʻokolohua. ʻO ka manaʻolana ʻo nā lāʻau hou a i ʻole nā hui hou o kēia mau lāʻau me ka chemotherapy a i ʻole ka radiation e hiki ai ke hoʻomaikaʻi hou i ke ola.
E noi i kāu kauka inā kūpono kahi lāʻau immunotherapy nou. E ʻike pehea e hoʻomaikaʻi ai kēia mau lāʻau i kou lapaʻau ʻana i ka maʻi ʻaʻai, a he aha nā hopena i hiki iā lākou ke kumu.