ʻNinglelo Aʻo hua hua waina: Hiki iā ia ke launa pū me nā lāʻau maʻamau

Anter

• Pehea e launa pū ai me nā lāʻau?
• 1-3: ʻO kekahi mau lāʻau kolesterol
• 4-7: ʻO kekahi mau lāʻau kaomi koko
• 8-9: ʻO kekahi mau lāʻau lapaʻau rhythm puʻuwai
• 10–13: ʻO kekahi mau lāʻau anti-maʻi
• 14–20: Nā ʻano ʻona he nui
• 21-24: Kekahi koko lahilahi
• 25-27: ʻO kekahi mau lāʻau ʻeha
• 28-31: ʻO kekahi mau hana erectile a me nā lāʻau prostate
• Pono ʻoe e hāʻawi i ka hua waina?
• Ke laina lalo

ʻO ka hua waina ka hua citrus ono me nā pono olakino he nui. Eia nō naʻe, hiki ke launa pū me kekahi lāʻau lapaʻau maʻamau, e hoʻololi ana i ko lākou hopena ma kou kino.

Inā makemake ʻoe e pili ana i ka wānana ʻana i ka huaʻulu i nā lāʻau he nui, e kōkua kēia ʻatikala iā ʻoe e hoʻomaopopo i ke kumu o laila a me nā koho āu.

Eia ke nānā pono loa ʻana i nā lāʻau maʻamau he 31 e loaʻa paha nā pilina weliweli me ka huaora, a me kekahi mau koho ʻē aʻe.

Kaha: Aia kēia ʻatikala i ka ʻike ākea - ʻaʻole ʻōlelo aʻoaʻo kūikawā. E kamaʻilio me kāu kauka ma mua o ka loli ʻana i kāu hoʻohana ʻana i nā lāʻau.

Pehea e launa pū ai me nā lāʻau?

Hoʻomaʻamaʻa ʻia nā lāʻau i kou ake a me kou ʻōpū liʻiliʻi e kahi hui pilikino o nā protein i kapa ʻia ʻo cytochrome P450 (CYPs).

Uha nā CYP i nā lāʻau lapaʻau, hoʻemi i ke kiʻekiʻe o ke koko o ka nui o lākou.

ʻO ka hua waina a me kekahi o kona mau hoahānau pili, e like me nā alani Seville, tangelos, pomelos, a me Minneolas, loaʻa kahi papa o nā kemika i kapa ʻia ʻo furanocoumarins.

Hoʻopilikia ʻo Furanocoumarins i ka hana maʻamau o CYPs. ʻO ka ʻoiaʻiʻo, hōʻike nā noiʻi e hoʻonui lākou i nā kiʻekiʻe o ke koko ma mua o 85 mau lāʻau (1).

Ma ka hoʻolōʻihi ʻana i ke ala e wāwahi pinepine ai nā CYP i nā lāʻau i loko o kou ʻōpū a me ke ake, hiki i ka huaʻulu ke hoʻonui i nā hopena o kēia mau lāʻau (1).

ʻEkolu mau mea e ʻike e maopopo ai a pehea e hiki ai iā ʻoe ke hoʻopau palekana i ka huaʻulu me kēia mau lāʻau.

1. ʻAʻole lawe nui ia. Hoʻokahi wale ka grapefruit a i ʻole hoʻokahi aniani o ka wai grapefruit e lawa e hoʻololi i ka hopena o kēia mau lāʻau iā ʻoe.
2. Ua hala nā hopena i kekahi mau lā. ʻO ka hiki i ka Grapefruit ke hoʻopili i ka lāʻau no 2-3 mau lā. ʻO ka lawe ʻana i kāu lāʻau i kekahi mau hola kaawale mai ka ʻai ʻana ʻaʻole lawa.
3. He mea nui. No kahi liʻiliʻi o nā lāʻau, hiki i nā hopena o ka grapefruit ke koʻikoʻi.

Me ka noʻonoʻo, eia ka ʻike kikoʻī e pili ana i 32 mau lāʻau lapaʻau maʻamau i hiki ke launa pū me ka huaora, i hoʻokaʻawale ʻia e ka hoʻohana.

1-3: ʻO kekahi mau lāʻau kolesterol

Hoʻopili ʻia kekahi mau lāʻau kolesterol i kapa ʻia he statins e ka grapefruit.

Hana ʻo Statins ma ka palena ʻana i ka hana maoli o ka cholesterol. Hoʻomaikaʻi kēia i ka ʻikepili o nā lipoproteins i ke koko a hoʻemi i ka make ʻana mai nā maʻi puʻuwai i nā mea maʻi e makaʻu ana iā ia ().

Hiki i nā Statins ke kumu i ka rhabdomyolysis, a i ʻole ka haki ʻana o nāʻiʻo puʻupuʻu. ʻO kēia ke alakaʻi i ka nāwaliwali o nā mākala, ʻeha, a me nā hōʻino ʻana o ka puʻuwai i kekahi manawa.

Hoʻonui ka hua waina i nā kiʻekiʻe o ke koko o ʻekolu mau statins maʻamau, e hoʻonui ana i ka makaʻi o ka rhabdomyolysis ():

1. Atorvastatin (Lipitor)
2. Lovastatin (Mevacor)
3. Simvastatin (Zocor)

Ua hōʻike ʻia kahi noiʻi ʻana e inu ana i ke kīʻaha o ka wai huaʻalani me simvastatin a i ʻole lovastatin hoʻonui i nā kiʻekiʻe o ke koko o kēia statins e 260% ().

Nā koho ʻē aʻe: Pravastatin (Pravachol), rosuvastatin (Crestor), a me fluvastatin (Lescol) mai launa pū me ka huaora (1).

Hiki i ka huaʻulu ke hoʻonui i nā hopena o kekahi mau lāʻau statin cholesterol, e hōʻino ana i nā mākala.

4-7: ʻO kekahi mau lāʻau kaomi koko

ʻAʻole hoʻopili ʻia ka hapa nui o nā ʻano kaomi koko e ka grapefruit.

Eia nō naʻe, pono e hoʻohana akahele i nā lāʻau ʻehā o ke kaomi koko e hiki mai ana:

1. Felodipine
2. Nifedipine (Procardia)
3. Losartan (Cozaar)
4. Eplerenone (Inspra)

ʻO nā lāʻau mua ʻelua i kēia papa inoa i kapa ʻia he blockers channel calcium. Hana lākou ma o ka hoʻololi ʻana i ke ala o kāu kīʻaha koko e hoʻohana ai i ka calcium, hoʻomaha i nā kīʻaha, a me ka hoʻomaha ʻana i ke koko.

ʻO nā lāʻau ʻelua hope loa i kēia papa inoa e hana nei ma ka hōʻemi ʻana i ka hana o kahi hormone i kapa ʻia angiotensin 2, kahi e hoʻonui maoli ai i ke kahe o ke koko.

Ua hoʻonui nui ʻia kahi pae o ke koko o ka nifedipine ke lawe ʻia me kahi o 2 mau kīʻaha (500 ml) o ka wai huaʻalani, ke hoʻohālikelike ʻia me ka wai ʻole. ʻO kēia ka hopena i ka hāʻule wikiwiki ʻana o ke kahe o ke koko, kahi mea weliweli ke mālama ʻole ʻia ().

He mea maʻamau ʻole ʻo Losartan i ka hoʻoliʻiliʻi ʻana o ka huaʻō i kāna hopena, ka palena palena paha i kona hiki ke kaohi i ke kaomi koko ().

Hana like ʻo Eplerenone i ka losartan, akā hoʻonui ʻia kona mau pae ke lawe ʻia me ka huaʻulu. Hiki i nā pae eplerenone keu ke kumu i ka nui o ka pāhare potassium i ke koko, i hiki ke hoʻopilikia i ka puʻuwai puʻuwai (1).

Nā koho ʻē aʻe: ʻO Spironolactone (Aldactone), kahi lāʻau like me losartan a me eplerenone, ʻaʻole e launa pū me ka huaora. ʻO Amlodipine (Norvasc) kahi poloka kalipona e like me felodipine a me nifedipine, ʻaʻole pili pū kekahi me ka grapefruit (,).

ʻOiai ʻaʻole hoʻopili ka grapefruit i ka hapa nui o nā lāʻau kaomi koko, hiki iā ia ke kumu i kekahi mau lāʻau e ʻoi aʻe i ke kahe o ke koko.

8-9: ʻO kekahi mau lāʻau lapaʻau rhythm puʻuwai

Hoʻoikaika ka huaola i kekahi mau lāʻau e mālama i nā puʻuwai puʻuwai abnormal.

Hiki ke weliweli loa kēia mau pilina a komo pū me:

1. Amiodarone
2. ʻO Dronedarone (Multaq)

Ua hāʻawi ʻia kahi noiʻi i 11 mau kāne e lawe ana i amiodarone i ke kīʻaha o ka wai huaʻulu (ma kahi o 300 ML). Hoʻonui ʻia nā pae lāʻau i 84%, hoʻohālikelike ʻia me ka poʻe inu ʻole i ka wai ().

He kuleana koʻikoʻi kēia mau lāʻau ʻelua i ka mālama ʻana i ke olakino o nā mea maʻi me nā maʻi puʻuwai puʻuwai. ʻO nā loli e pili ana i ka hua hua i loko o nā pae o kēia mau lāʻau i hana i kekahi manawa i nā loli puʻuwai puʻuwai weliweli.

ʻOiai ʻo kahi mau lāʻau puʻuwai puʻuwai wale nō e launa pū me ka grapefruit, hiki i nā hopena ʻino ke weliweli.

10–13: ʻO kekahi mau lāʻau anti-maʻi

Ua kapa ʻia he antimicrobial, he ʻokoʻa ka nui o kēia mau lāʻau anti-maʻi i kā lākou hana a me ka haki ʻana o ke kino.

ʻOiai ʻo nā antimicrobial kekahi o nā ʻano ʻāpana like ʻole o nā lāʻau, aia wale nō kekahi mau lāʻau lapaʻau me ka launa pū ʻana o ka huaʻōlani koʻikoʻi.

1. ʻErythromycin
2. Rilpivirine a me nā lāʻau e pili ana i ka maʻi HIV
3. ʻO Primaquine a me nā lāʻau antimalarial pili
4. Albendazole

Hoʻohana ʻia ʻo Erythromycin e mālama i kekahi ʻano o nā maʻi bacteria. ʻO kahi noiʻi e hoʻohālikelike ana i ka wai huaʻikuʻi me ka wai i nā mea maʻi e lawe ana i ka erythromycin i hōʻike ʻia ua hoʻonui ka wai i nā kiʻekiʻe o ke koko o ka lāʻau e 84% ().

Hiki i nā pae keu o kēia lāʻau ke hōʻoki i ka mana o ka naʻau ().

Hoʻonui pū ka huaola i nā pae o nā lāʻau HIV rilpivirine a me maraviroc, a me nā lāʻau antimalarial e pili ana i ka primaquine. Hiki i kēia ke hoʻololi i ka mana o ka puʻuwai a i ʻole ka hana (1).

Ma muli o ka lawe pinepine ʻana i nā antimicrobial no kahi manawa palena, malia paha he maʻalahi ka hōʻalo maʻalahi i ka lawe ʻana i kēia mau lāʻau.

Nā koho ʻē aʻe: ʻO Clarithromycin kahi lāʻau i ka papa like e like me ka erythromycin e launa ʻole me ka huaora. ʻO Doxycycline kahi lāʻau antibiotic a me nā lāʻau antimalarial ʻaʻole pili pū me ia (1).

ʻAʻole pono e hoʻohana ʻia kekahi mau lāʻau lapaʻau anti-maʻi me ka grapefruit, no ka mea hiki iā lākou ke alakaʻi i ka haʻalulu a me ka hana o ka puʻuwai.

14–20: Nā ʻano ʻona he nui

ʻO ka hapa nui o nā lāʻau antidepressants a me nā anti-hopohopo e palekana e hoʻohana me ka grapefruit.

Eia nō naʻe, hana pū kekahi mau lāʻau ʻano me ia, me:

1. ʻO Quetiapine (Seroquel)
2. Lurasidone (Latuda)
3. Ziprasidone (Geodon)
4. ʻO Buspirone (Buspar)
5. Diazepam (Valium)
6. Midazolam (Versed)
7. ʻO Triazolam (Halcion)

Hoʻohana ʻia nā lāʻau e like me quetiapine a me lurasidone e mālama ai i ke ʻano o ka naʻau a me nā ʻano o ka lawena. Hiki ke hoʻonui i nā pae o kēia mau lāʻau i hiki ke hoʻololi i ka ritme o ka naʻau a i ʻole ka hiamoe (1).

Eia kekahi, ʻo ka diazepam, ka midazolam, a me ka triazolam he mau mea hoʻohiamoe i hoʻohana ʻia i kekahi manawa no ka hōʻeha weliweli a i ʻole nā ​​ʻano hopohopo.

Hoʻohālikelike hoʻokahi noiʻi i kekahi o kēia mau lāʻau i ʻeiwa mau maʻi, a ʻo kekahi o lākou i hoʻopau i ka huaora. Ua hōʻike ʻia hiki i ka grapefruit ke hoʻonui i nā hopena o kēia mau lāʻau, i ka hopena i ka nui o ka hiamoe ().

ʻO ka ʻai ʻana i ka grapefruit ʻoiai ke lawe nei i nā lāʻau e pili ana i ka naʻau i luna ke hopena i nā loli o ka puʻuwai puʻuwai, ka hiamoe nui, a me nā hopena kikoʻī.

21-24: Kekahi koko lahilahi

Hoʻohana ʻia nā mea lahilahi o ke koko e mālama a pale aku paha i nā hāle koko. Hoʻopili ʻia kekahi o lākou e ka grapefruit, me:

1. Apixaban (Eliquis)
2. ʻO Rivaroxaban (Xarelto)
3. ʻO Clopidogrel (Plavix)
4. ʻO Ticagrelor (Brilinta)

Pili ʻo Clopidogrel i ka CYPs - nā protein i kaupalena ʻia ka grapefruit - e holo. No laila, lilo ia i mea ʻemi ke hoʻohui ʻia me ka huaʻulu.

ʻO kahi noiʻi o 7 mau mea maʻi e lawe ana i ka clopidogrel me 200 mL o ka wai grapefruit a i ʻole ka wai i hōʻike i ka hoʻohaʻahaʻa haʻahaʻa o ka lāʻau me ka wai. Eia nō naʻe, ʻaʻole i pili kona hiki ke mālama i nā kīʻaha koko ().

Hoʻohālikelike, hoʻonui ka grapefruit i nā kiʻekiʻe o ke koko o nā lāʻau ʻē aʻe ma kēia papa inoa, kahi e hopena ai i ke kahe ʻana ().

Nā koho ʻē aʻe: Hoʻohana ʻia ʻo Warfarin (Coumadin) no nā kumu e like me nā apixaban a me rivaroxaban. ʻOiai maʻalahi ka warfarin i nā meaʻai i loaʻa ka lāʻau K, ʻaʻole e hoʻopili ʻia ka hoʻoulu ʻana e ka grapefruit ().

Hoʻopili ʻia kekahi mau mea lahilahi koko e ka huaʻulu. Hiki i kēia ke alakaʻi i ke kahe ʻana a i ʻole ka pale ʻana i ke kahe o ke koko.

25-27: ʻO kekahi mau lāʻau ʻeha

Hoʻopili ʻia nā lāʻau ʻeha he nui e ka huaʻulu.

1. ʻO Fentanyl
2. ʻOxycodone
3. Colchisin

ʻO Fentanyl a me ka oxycodone nā mea ʻehaʻeha narcotic. ʻOiai e hoʻopili iki ʻia kā lākou pae koko e ka liʻiliʻi o ka grapefruit, hiki ke hoʻololi i ka lōʻihi o ko lākou noho ʻana i ke kino (,).

ʻO Colchisin kahi lāʻau kahiko i hoʻohana ʻia e mālama i ka maʻi gout. Hoʻomaʻamaʻa ʻia e CYPs a hiki ke launa pū me ka grapefruit. Eia nō naʻe, ua hōʻike ʻia kahi noiʻi 2012 e inu ana i ka wai huaʻōlani he 240 ml wale nō ka hopena liʻiliʻi ma kāna pae ().

Nā koho ʻē aʻe: ʻO Morphine a me Dilaudid he mau mea hōʻeha ʻeha narcotic ʻaʻole i hoʻopili ʻia e ka grapefruit (1).

ʻO kekahi mau mea ʻeha narcotic e hoʻomau hou i ke koko ke lawe ʻia me ka huaora.

28-31: ʻO kekahi mau hana erectile a me nā lāʻau prostate

Pono kekahi mau hana erectile a me nā lāʻau prostate e pili ana i ka launa pū ʻana o ka huaʻalani.

1. Sildenafil (Viagra)
2. ʻO Tadalafil (Cialis)
3. Tamsulosin (Flomax)
4. Silodosin (Rapaflo)

ʻO nā lāʻau lapaʻau erectile e like me sildenafil a me ka hana tadalafil e ka hoʻomaha ʻana i nā kīʻaha koko, kahi e hoʻonui ai i ke kahe o ke koko i kahi kūkulu.

Ma muli o ka hoʻomaha ʻana o nā kīʻaha koko ʻē aʻe me kēia mau lāʻau, ʻo ka piʻi ʻana o ke kiʻekiʻe o ke koko o kēia mau lāʻau i hana ʻia e ka huaʻulu hiki ke hoʻemi i ke kaomi koko ().

Eia kekahi, ʻo nā lāʻau hoʻomāhuahua prostate e like me tamsulosin hiki ke hoʻoulu i ka luʻuluʻu a me ke kahe o ke koko ke lawe ʻia me ka huaʻulu ().

Nā koho ʻē aʻe: ʻO kekahi papa o ka hoʻomāhuahua prostate i nā lāʻau lapaʻau, i komo pū me finasteride a me dutasteride, ʻaʻole i hoʻopili nui ʻia e ka grapefruit ().

ʻAʻole pono e hoʻopau ʻia ka hua waina me nā lāʻau lapaʻau erectile a i ʻole kekahi mau lāʻau hoʻonui prostate.

Pono ʻoe e hāʻawi i ka hua waina?

ʻOiai ka papa inoa o kēia ʻatikala i 31 mau lāʻau maʻamau e launa pū me ka grapefruit, ʻaʻole ia he papa inoa piha.

Hāʻawi ʻo Drugs.com i kahi loiloi launa lāʻau e hiki iā ʻoe ke hoʻohana e nānā i kāu mau lāʻau no ka launa pū.

Hoʻohui ʻia, Rxlist.com papa inoa i kekahi mau lāʻau lapaʻau liʻiliʻi e launa pū me ka huaora.

He mea nui e hoʻomanaʻo he hoʻokahi wale nō grapefruit a i ʻole ma kahi o kahi kīʻaha wai nui e lawa ai e hoʻololi i nā pae o ke koko o nā lāʻau he nui. A ʻo kekahi o kēia mau lāʻau i loaʻa paha nā hopena ʻino ke hui pū lākou me ka grapefruit.

Inā ʻoe e lawe i nā lāʻau i kēia manawa me nā launa ʻana o ka grapefruit, e kuapo i kahi lāʻau ʻē aʻe a i ʻole hoʻopau i ka ʻai ʻana i ka huaʻulu.

Inā kānalua, e kiʻi i kāu kauka a kauka paha no ka ʻōlelo aʻoaʻo pilikino.

ʻOiai ʻo ka liʻiliʻi o ka grapefruit hiki ke launa pū me kekahi mau lāʻau a hana i nā hopena koʻikoʻi.

Ke laina lalo

Hoʻopilikia ka hua waina i nā protein i loko o ka ʻōpū liʻiliʻi a me ke akepaʻa e wāwahi pinepine i nā lāʻau.

ʻO ka ʻai ʻana i ka huaʻulu a me ka inu ʻana i ka wai momona a ke lawe nei i kēia mau lāʻau i hiki ke alakaʻi i nā kiʻekiʻe kiʻekiʻe o lākou i kou koko - a me nā hopena ʻē aʻe.

Me kekahi mau lāʻau, me nā liʻiliʻi o ka grapefruit hiki ke hōʻeha i nā hopena ʻino. No laila, pono e hōʻalo i ka hui ʻana.

Hoʻomaopopo paha kāu kauka lāʻau i kēia mau lāʻau lapaʻau me ka ʻōlelo wīwī i ka launa pū ʻana.

E ʻike pono i kāu kauka a me ka lāʻau lapaʻau inā ʻoe e ʻai mau i ka grapefruit. Hiki iā lākou ke kōkua iā ʻoe e hoʻoholo inā palekana ka ʻai ʻana iā ia ma kekahi mau lāʻau.