He aha ka Dopamine Deficit Syndrome?

Anter

• He aha nā hōʻailona?
• He aha ke kumu o kēia ʻano?
• ʻO wai ka pilikia?
• Pehea ia ʻike?
• Pehea e mālama ʻia ai?
• Pehea e pili ai i ke ola?

He mea maʻamau kēia?

ʻO ka maʻi deficit Dopamine kahi kūlana hoʻoilina i loaʻa iā 20 wale nō i hōʻoia ʻia. ʻIke ʻia ʻo ia ʻo ka maʻi hōʻemi transporter dopamine a me ka parkinsonism-dystonia pēpē.

Hoʻopili kēia ʻano i ka hiki i ke keiki ke neʻe i ko lākou kino a me nā mākala. ʻOiai ʻike ʻia nā ʻōuli i ka wā pēpē, ʻaʻole ʻike ʻia a hiki i ka wā kamaliʻi.

Kūlike nā ʻōuli me nā maʻi neʻe ʻē aʻe, e like me ka maʻi ʻōpio Parkinson. Ma muli o kēia, pinepine Manaʻo kekahi mau kānaka noiʻi he mea maʻamau ia ma mua o ka mea i manaʻo mua ʻia.

Holomua kēia ʻano, ʻo ia hoʻi e pōʻino ana i ka hala ʻana o ka manawa. ʻAʻohe mea ola, no laila kau ka mālama i ka mālama ʻana i nā ʻōuli.

E hoʻomau i ka heluhelu ʻana e aʻo hou aʻe.

He aha nā hōʻailona?

Kūlike mau nā ʻōuli me ka nānā ʻole i nā makahiki a lākou e ulu ai. Pākuʻi ʻia kēia mau mea:

• ʻūpē mākala
• ʻūpē mākala
• haʻalulu
• neʻe lohi loa nā mākala (bradykinesia)
• ʻāʻī puʻupuʻu (ʻoʻoleʻa)
• kōpaʻa
• pilikia i ka ʻai ʻana a me ka ale ʻana
• paʻakikī i ka ʻōlelo ʻana a me ka hoʻokumu ʻana i nā huaʻōlelo
• nā pilikia e paʻa ana i ke kino i kahi kū i luna
• nā pilikia me ke kaulike ke kū a me ka hele wāwae
• neʻe ʻole o ka maka o ka maka

Hiki i nā ʻōuli ʻē aʻe ke:

• maʻi reflux gastroesophageal (GERD)
• pākī pinepine ʻana o ka niumonia
• paʻakikī i ka hiamoe

He aha ke kumu o kēia ʻano?

Wahi a ka Waihona Waihona Lapaʻau o ʻAmelika Hui Pū ʻIa, ua hoʻokumu ʻia kēia maʻi genetical e nā hoʻololi ʻana i ka SLC6A3 ʻāpana Pili kēia ʻāpana i ka hana ʻana o ka protein transporter dopamine. Mālama kēia protein i ka nui o ka lawe ʻia o ka dopamine mai ka lolo i nā ʻāpana like ʻole.

Pili ʻo Dopamine i nā mea āpau mai ka ʻike a me ka naʻau, i ka hiki ke hoʻoponopono i nā neʻe o ke kino. Inā haʻahaʻa loa ka nui o ka dopamine i loko o nā hunaola, hiki iā ia ke hoʻopili i ka kaohi o nā mākala.

ʻO wai ka pilikia?

ʻO ka maʻi deficit Dopamine kahi maʻi maʻi, ʻo ia hoʻi ua hānau ʻia kahi kanaka me ia. ʻO ka mea nui weliweli ka makeup genetical o nā mākua o ke keiki. Inā loaʻa i kekahi mau mākua hoʻokahi kope o ka mutated SLC6A3 ʻāpana, e loaʻa i kā lāua keiki i ʻelua kope o ka ʻāpana i hoʻololi ʻia a loaʻa ka maʻi i kēia maʻi.

Pehea ia ʻike?

ʻO ka manawa pinepine, hiki i ke kauka o kāu keiki ke hana i kahi hōʻailona ma hope o ka nānā ʻana i nā pilikia i loaʻa iā lākou me ke kaulike a me ka neʻe. E hōʻoia ke kauka i ka hōʻailona ma ka lawe ʻana i kahi hōʻailona koko e hoʻāʻo no nā hōʻailona genetika o kēia kūlana.

Hiki iā lākou ke lawe i kahi laʻana o ka wai cerebrospinal e nānā no nā waikawa e pili ana i ka dopamine. ʻIke ʻia kēia ma ke ʻano he.

Pehea e mālama ʻia ai?

ʻAʻole kahi papa hana lapaʻau maʻamau no kēia kūlana. Pono pinepine ka hoʻāʻo a me ka hemahema e hoʻoholo ai i nā lāʻau i hiki ke hoʻohana ʻia no ka mālama ʻana i nā ʻōuli.

ua loaʻa hou ka kūleʻa i ka mālama ʻana i nā maʻi neʻe e pili ana i ka hana dopamine. ʻO kahi laʻana, ua hoʻohana kūleʻa ʻia ʻo levodopa e hōʻoluʻolu i nā ʻōuli o ka maʻi o Parkinson.

ʻO Ropinirole a me pramipexole, he mau antagonists dopamine, ua hoʻohana ʻia e mālama i ka maʻi o Parkinson i ka poʻe mākua. Ua noi nā kānaka noiʻi i kēia lāʻau i ka maʻi hānai dopamine. Eia nō naʻe, pono hou ʻia kahi noiʻi hou e hoʻoholo i nā hopena hopena pōkole a me ka wā lōʻihi.

ʻO nā hoʻolālā ʻē aʻe no ka mālama ʻana a me ka mālama ʻana i nā ʻōuli e like me nā ʻano neʻe ʻē aʻe. Hoʻopili kēia i nā lāʻau a me nā loli nohona e mālama ai:

• ʻoʻoleʻa o ka mākala
• maʻi kīnā
• nā pilikia hanu
• GERD
• kōpaʻa

Pehea e pili ai i ke ola?

ʻO nā keiki pēpē a me nā keiki me ka maʻi hākōkō o ka lawe ʻana i ka dopamine paha he pōkole ke ola. ʻO kēia no ka mea ʻoi aku ka maʻalahi o lākou i nā maʻi maʻi a me nā maʻi hanu ʻē aʻe i hoʻoweliweli.

I kekahi mau hihia, ʻoi aku ka maikaʻi o ka maka o ke keiki ke ʻole e kū ko lākou mau ʻōuli i ka wā kamaliʻi.