Selegiline
Anter
- Ma mua o ka lawe ʻana i selegiline,
- Hiki i Selegiline ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka:
- Pākuʻi ʻia paha nā ʻōuli o ka overdose:
Hoʻohana ʻia ʻo Selegiline e kōkua i ke kaohi ʻana i nā ʻōuli o ka maʻi o Parkinson (PD; kahi maʻi o ka ʻōnaehana e hoʻopilikia i ka neʻe ʻana, ka mālama ʻana i nā mākala, a me ke kaulike) i ka poʻe e lawe nei i ka hui levodopa a me ka carbidopa (Sinemet). Hiki paha i Selegiline ke kōkua i ka poʻe me ka maʻi o Parkinson ma o ka hōʻemi ʻana i ka lāʻau o levodopa / carbidopa e pono ai e kaohi i nā ʻōuli, e hoʻōki ana i nā hopena o ka levodopa / carbidopa mai ke kau ʻana ma waena o nā lāʻau, a e hoʻonui ana i ka lōʻihi o ka manawa e hoʻomau ka levodopa / carbidopa i ka mālama ʻana i nā ʻōuli. Aia ʻo Selegiline i kahi hui o nā lāʻau i kapa ʻia ʻo monoamine oxidase type B (MAO-B) nā mea kāohi. Hana ia ma ka hoʻonui ʻana i ka nui o ka dopamine (kahi mea kūlohelohe e pono ai e kaohi i ka neʻe) i ka lolo.
Hele mai ʻo Selegiline ma ke ʻano he capsule a me kahi papa hoʻohaʻahaʻa waha (hoʻopau) e lawe ma ka waha. Lawe pinepine ʻia ka capsule i ʻelua mau manawa i ka lā me ka ʻaina kakahiaka a me ka ʻaina awakea. Lawe pinepine ʻia ka papa hoʻoluʻu waha i ka lā hoʻokahi ma mua o ka ʻaina kakahiaka me ka ʻole o ka meaʻai, ka wai, a me nā wai ʻē aʻe. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pono i ka selegiline e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka. Inā ʻoe e lawe i kahi selegiline he nui loa, ʻike paha ʻoe i ka piʻi a weliweli hoʻi o kāu kaomi koko.
Inā ʻoe e lawe i ka papa hoʻohiehie waha, mai wehe i ka blister i loaʻa nā papa mai ka ʻeke o waho a hiki i kou mākaukau e lawe i kahi lāʻau. Ke hiki i ka manawa no kāu lāʻau, e hemo i ka kāleka blister mai ka ʻeke o waho a hoʻohana i nā lima maloʻo e ihi i hoʻokahi kīʻaha. Mai hoʻāʻo e pahu i ka papa i loko o ka pepa kini. E kau i ka pā ma kou alelo a kali a hemo ia. Mai ale i ka papa. Mai ʻai a inu paha i kekahi mea no 5 mau minuke ma mua o kou lawe ʻana i ka pākaukau a no 5 mau minuke ma hope o kou lawe ʻana i ka papa.
Inā ʻoe e lawe i ka papa hoʻohiehie waha, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi haʻahaʻa o ka selegiline a hoʻonui i kāu lāʻau ma hope o ʻeono pule.
E haʻi i kāu kauka inā ʻike ʻoe i ka nausea, ka ʻeha o ka ʻōpū, a me ka ʻoliʻoli. Hiki i kāu kauka ke hōʻemi i kāu lāʻau o levodopa / carbidopa i ka wā o kou mālama ʻana me selegiline, keu hoʻi inā ʻike ʻoe i kēia mau hōʻailona a i ʻole nā hōʻailona ʻē aʻe. E hāhai pono i kēia mau ʻōkuhi a nīnau i kāu kauka a kauka paha inā ʻaʻole ʻoe e ʻike i ka nui o nā lāʻau āu e lawe ai. Mai hoʻololi i nā koina o kekahi o kāu mau lāʻau inā ʻaʻole haʻi kāu kauka iā ʻoe.
Hiki i Selegiline ke kōkua i ka mālama ʻana i nā ʻōuli o PD, akā ʻaʻole ia e hoʻōla i ke ʻano. Mai hōʻoki i ka lawe ʻana i selegiline me ke kamaʻilio ʻole ʻana me kāu kauka. Inā kū koke ʻoe i ka lawe ʻana i nā lāʻau no ka maʻi o Parkinson e like me selegiline, ʻike paha ʻoe i ke kuni, ka hou ʻana, nā mākala ʻoʻoleʻa, a me ka nalo o ka noʻonoʻo. Kāhea i kāu kauka inā ʻike ʻoe i kēia a i ʻole nā hōʻailona ʻē aʻe ma hope o kou kū ʻana i ka lawe selegiline.
Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.
Ma mua o ka lawe ʻana i selegiline,
- e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka selegiline, a i ʻole nā lāʻau ʻē aʻe.
- e haʻi i kāu kauka inā e lawe ana ʻoe, lawe koke paha, a i ʻole hoʻolālā e lawe i kekahi o nā lāʻau i kuhikuhi ʻia a me nā lāʻau i hōʻike ʻole ʻia: dextromethorphan (Robitussin); meperidine (Demerol); methadone (Dolophine), propoxyphene (Darvon); tramadol (Ultram, i Ultracet); a me nā lāʻau ʻē aʻe i loaʻa ka selegiline (Eldepryl, Emsam, Zelapar). E haʻi paha kāu kauka iā ʻoe mai lawe i ka selegiline inā ʻoe e lawe a i ʻole lawe i kekahi o kēia mau lāʻau. Inā kū ʻoe i ka lawe ʻana i selegiline, hiki i kāu kauka ke ʻōlelo aku iā ʻoe ʻaʻole e lawe i kēia mau lāʻau a hiki i ka hala ʻana o 14 mau lā ma hope o kou lawe ʻana i selegiline.
- e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻowaiwai a me nā huahana lāʻau āu e lawe nei. E haʻi pono i kekahi o kēia mau mea: antidepressants e like me amitriptyline (Elavil) a me imipramine (Tofranil); carbamazepine (Carbatrol, Equetro); nā lāʻau no ke kahe a me nā hōʻailona anu a i ʻole no ka pohō kaumaha; nafcillin; phenobarbital; phenytoin (Dilantin); nā mea hoʻoliʻiliʻi serotonin reuptake e like me citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), a me sertraline (Zoloft); a me rifampin (Rifadin, Rimactane). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a e nānā pono paha iā ʻoe no nā hopena ʻaoʻao.
- e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate a me nā puʻupaʻa.
- inā loaʻa iā ʻoe ka phenylketonuria (PKU; kahi ʻano hoʻoilina e pono ai e ukali ʻia kahi papaʻai kūikawā e pale ai i ka lolo o ka noʻonoʻo), pono ʻoe e ʻike i nā papa i hoʻokaʻawale waha ʻia i loko o ka phenylalanine.
- e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i selegiline, e kāhea i kāu kauka.
- pono ʻoe e ʻike ʻo ka selegiline ke kumu o ka hoʻoluhi, hoʻomālamalama, a me ka maʻule ke ala koke ʻoe mai kahi kūlana wahaheʻe. ʻOi aku ka maʻamau o kēia ke hoʻomaka mua ʻoe e lawe i ka selegiline. I mea e hōʻalo ai i kēia pilikia, e hele mālie i waho o kahi moe, e hoʻomaha ana i kou mau wāwae i ka papahele no kekahi mau minuke ma mua o ke kū ʻana i luna.
E noi i kāu kauka inā pono ʻoe e hōʻalo i nā meaʻai i kou wā e mālama ai me selegiline. E haʻi paha kāu kauka iā ʻoe hiki iā ʻoe ke hoʻomau i kāu papaʻai maʻamau ke lawe ʻoe i selegiline e like me ke kuhikuhi.
E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no kāu kaukona aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau.Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.
Hiki i Selegiline ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
- ʻūpā
- ʻālohilohi
- maule ana
- waha maloo
- nausea
- ka luaʻi
- ʻeha ka ʻōpū
- paʻakikī i ka ale ʻana
- puʻuwai puʻuwai
- pāhoehoe
- ʻenekini
- kōpaʻa
- paʻakikī e hiamoe a hiamoe paha
- moeʻuhane ʻano ʻole
- hiamoe
- kaumaha
- ʻeha, keu hoʻi i nā wāwae a hoʻi i hope
- ʻehaʻeha a nāwaliwali paha
- nā poni ʻulaʻula ma ka ʻili
- hūwī
- ʻulaʻula, huhū, a ʻeha hoʻi i ka waha (inā ʻoe e lawe i nā papa hoʻohiehie waha waha)
Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka:
- ʻeha poʻo poʻo
- ʻeha ka umauma
- wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
- ka houʻu ʻana
- ʻāwīwī, luuluu nui a luaʻi
- huikau
- ʻāʻī ʻoʻoleʻa a ʻeha paha
- ke hoʻoluliluli ʻole ʻole ʻana i kahi ʻāpana o kou kino
- neʻe ʻole i paʻakikī e kaohi
- hallucination (ke ʻike nei i ka mea a i ʻole ka lohe ʻana i nā leo i ʻole)
- paʻakikī i ka hanu ʻana
Hiki i ka poʻe i loaʻa iā PD ke hoʻonui i ka makaʻu o ka hoʻomohala melanoma (kahi ʻano o ka maʻi ʻaʻai ʻili). ʻAʻole lawa ka ʻike e haʻi ai inā he selegiline a i ʻole nā lāʻau ʻē aʻe no PD e hoʻonui ai i ka makaʻu o melanoma. E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i selegiline a inā paha e nānā ʻia kou ʻili i kāu mālama ʻana.
Hoʻokumu paha ʻo Selegiline i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.
E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. E hoʻolei i nā papa hoʻokaʻawale waha waha ʻole i hoʻohana ʻole ʻia ʻekolu mau mahina ma hope o kou wehe ʻana i ka ʻeke pale.
Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.
He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org
I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.
Pākuʻi ʻia paha nā ʻōuli o ka overdose:
- hiamoe
- ʻūpā
- maule
- ukiuki
- hyperactivity
- hoohaunaele
- ʻeha poʻo poʻo
- hallucination (ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole ola)
- ʻāʻī paʻa
- ʻoʻoleʻa a hoʻopaʻa ʻia o ke kua
- ka hopu ʻana
- koma (nalo o ka noʻonoʻo no kahi manawa o ka manawa)
- wikiwiki a me ka pā ʻole o ka lāʻau ikiʻai
- ʻeha ka umauma
- hanu lohi
- ka houʻu ʻana
- fiva
- anu, ʻili paʻalili
Mālama i nā manawa āpau me kāu kauka.
Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.
He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.
- ʻEldepryl®
- Zelapar®