Cyclophosphamide

Anter

• Ma mua o ka lawe ʻana i ka cyclophosphamide,
• Hiki i ka Cyclophosphamide ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana hoʻokahi ʻia ʻo Cyclophosphamide a i ʻole hui pū ʻia me nā lāʻau ʻē aʻe e mālama i ka lymphoma o Hodgkin (ka maʻi ʻo Hodgkin) a me ka lymphoma non-Hodgkin (ʻano o ka maʻi ʻaʻai e hoʻomaka i kahi ʻano o nā hunaola keokeo e hakakā maʻamau i ka maʻi); cutaneous T-cell lymphoma (CTCL, kahi hui o nā maʻi ʻaʻai o ka ʻōnaehana pale i ʻike mua ʻia e like me nā ʻili o ka ʻili); myeloma maha (kahi ʻano maʻi ʻaʻai o ka iwi iwi); a me kekahi mau ʻano leukemia (maʻi ʻaʻai o nā aʻa koko keʻokeʻo), e like me ka leukemia lymphocytic mau (CLL), leukemia myelogenous mau (CML), leukemia myeloid koʻikoʻi (AML, ANLL), a me ka leukemia lymphoblastic koʻikoʻi (ALL). Hoʻohana ʻia ia e mālama i ka retinoblastoma (maʻi ʻaʻai i ka maka), neuroblastoma (kahi maʻi ʻaʻa e hoʻomaka i nā pūnana nerve a kū nui i nā keiki), ka maʻi ʻaʻai ovarian (ka maʻi ʻaʻai e hoʻomaka i nā wahine hānau keiki kahi i hana ʻia nā hua. . Hoʻohana pū ʻia ʻo Cyclophosphamide e mālama i nā maʻi nephrotic (kahi maʻi i hōʻino ʻia e nā puʻupaʻa) i nā keiki i hoʻomaikaʻi ʻole ʻia ka maʻi, ua ʻoi aku ka maikaʻi, a ua hoʻi mai paha ma hope o ka lawe ʻana i nā lāʻau ʻē aʻe a i ʻole nā ​​keiki i ʻike i nā hopena i hiki ʻole ke hoʻomanawanui ʻia me nā mea ʻē aʻe. nā lāʻau. Aia ʻo Cyclophosphamide i kahi papa o nā lāʻau i kapa ʻia nā ʻākena alkylating. Ke hoʻohana ʻia ʻo cyclophosphamide e mālama i ka maʻi ʻaʻai, hana ia ma ka hoʻolohi a paʻa ʻana paha i ka ulu ʻana o nā hunaola maʻi ʻaʻai i loko o kou kino. Ke hoʻohana ʻia ʻo cyclophosphamide e mālama i ka maʻi nephrotic, hana ia ma ke kāohi ʻana i ka ʻōnaehana pale o kou kino.

Hele mai ʻo Cyclophosphamide ma ke ʻano he papa e lawe ma ka waha i hoʻokahi manawa i ka lā. Pili ka lōʻihi o ka mālama ʻana i nā ʻano lāʻau āu e lawe nei, pehea ka maikaʻi o ka pane ʻana o kou kino iā lākou, a me ke ʻano o ke kanesa a i ʻole ke ʻano maʻi āu. Lawe i ka cyclophosphamide ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe i ka cyclophosphamide e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Pono paha kāu kauka e hoʻolohi i kāu lāʻau lapaʻau a hoʻoponopono paha i kāu mahele lāʻau o cyclophosphamide ma muli o kāu pane i ka lāʻau a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. Mai hooki i ka lawe ʻana i ka cyclophosphamide me ka walaʻau ʻole ʻana me kāu kauka.

Hoʻohana pū ʻia ʻo Cyclophosphamide i kekahi manawa e mālama i kekahi ʻano maʻi ʻaʻai o ka maʻi (cancer cell lung cancer; SCLC). Hoʻohana ʻia ia e mālama i ka rhabdomyosarcoma (kahi ʻano maʻi ʻaʻai o nā mākala) a me ka sarcoma o Ewing (kahi ʻano maʻi ʻaʻai iwi) i nā keiki. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka hoʻohana ʻana i kēia lāʻau no kou maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka cyclophosphamide,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka cyclophosphamide, nā ʻākena alkylating ʻē aʻe e like me bendamustine (Treanda^®), busulfan (Myerlan^®, ʻO Busulfex^®), carmustine (BiCNU^®, ʻO Gliadel^® Wafer), mālamake (Leukeran^®), ifosfamide (Ifex^®), lomustine (CeeNU^®), melphalan (Alkeran^®), procarbazine (Mutalane^®), a i ʻole temozolomide (Temodar^®), kekahi mau lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i nā papa cyclophosphamide. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: allopurinol (Zyloprim^®), cortisone acetate, doxorubicin (Adriamycin^®, Doxil^®), hydrocortisone (Cortef^®), a i ʻole phenobarbital (Luminal^® Sodoma). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me cyclophosphamide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā ua loaʻa mua iā ʻoe ka lapaʻau me nā lāʻau chemotherapy ʻē aʻe a i ʻole inā he x-ray kāu i hala koke iho nei. E haʻi pū aku i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa paha i ka maʻi puʻuwai a i ʻole ate.
• pono ʻoe e ʻike i ka cyclophosphamide e hoʻopilikia i ka maʻamau maʻamau (manawa) i nā wahine a hoʻopau paha i ka hana sperm i nā kāne. Hoʻokumu paha ʻo Cyclophosphamide i ka infertility mau (paʻakikī e hāpai); Eia naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe ke hāpai a i ʻole hiki iā ʻoe ke hāpai i kekahi mea ʻē aʻe. ʻO nā wahine hāpai a hānai hānai paha e haʻi i kā lākou kauka ma mua o ka hoʻomaka ʻana e lawe i kēia lāʻau. ʻAʻole pono ʻoe e hoʻolālā i nā keiki i ka loaʻa ʻana o ka chemotherapy a i ʻole no kekahi manawa ma hope o nā mālama ʻana. (E kamaʻilio me kāu kauka no nā kikoʻī hou aʻe.) E hoʻohana i kahi ʻano pono o ka kaohi hānau e pale ai i ka hāpai keiki. Hoʻopilikia paha ʻo Cyclophosphamide i ka fetus.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe iā cyclophosphamide.

Inu i nā wai he nui ke hoʻohana ʻoe i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Cyclophosphamide ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• lilo o ka makemake a kaumaha paha
• abdominal eha
• pāhoehoe
• poho lauoho
• ʻeha ma ka waha a me ke alelo
• nā hoʻololi i ke kala o ka ʻili
• nā hoʻololi i ke kala a i ʻole ka ulu ʻana o nā kui kui a manamana hoʻi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• ʻeha ka ʻāʻī, ke kuni, ke anu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• hoʻōla hune ʻoluʻolu a lohi paha
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• ʻeke ʻeleʻele, hoʻolōʻihi
• mimiki ʻeha a mimi ʻulaʻula paha
• hūwī
• hives
• ʻūlili
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• pokole o ka hanu
• ʻūhā
• pehu i nā wāwae, nā kuʻekuʻe wāwae, a i ʻole nā ​​wāwae
• ʻeha ka umauma
• melemele o ka ʻili a me nā maka

Hiki i ka Cyclophosphamide ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i nā maʻi ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i nā makaʻu o ka lawe ʻana iā cyclophosphamide.

Hiki i ka Cyclophosphamide ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻeke ʻeleʻele, hoʻolōʻihi
• mimi ʻulaʻula
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• luhi ʻole a nawaliwali paha
• ʻeha ka ʻāʻī, ʻū, kuni, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• pehu i nā wāwae, nā kuʻekuʻe wāwae, a i ʻole nā ​​wāwae
• ʻeha ka umauma

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i cyclophosphamide.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Cytoxan^®¶

• CPM
• CTX
• CYT

^¶ ʻAʻole kēia huahana māka i ka mākeke hou. Hiki ke loaʻa nā koho ʻē aʻe.