ʻO Tazemetostat

Anter

• Ma mua o ka lawe ʻana i ka tazemetostat,
• Hoʻokumu paha ʻo Tazemetostat i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Tazemetostat e mālama i ka saritoma epithelioid (kahi maʻi maʻi maʻi laha ʻole e ulu lohi ana) i nā mākua a me nā keiki he 16 mau makahiki a ʻoi paha o ka makahiki i pālahalaha ʻia i nā mea kokoke a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke mālama maikaʻi ʻia me ke ʻoki kino. Hoʻohana ʻia ia e mālama i kekahi ʻano o ka lymphoma follicular (FL; kahi ʻano o ke kanesa e hoʻomaka i nā hunaola keokeo) i nā mākua i hoʻi a ʻaʻole i pane i nā lāʻau ʻē aʻe ʻelua. Hoʻohana ʻia ʻo Tazemetostat e mālama i ka lymphoma follicular i nā mākua i hoʻi a ʻaʻole i pane i ka lāʻau ke loaʻa ʻole nā ​​koho lapaʻau ʻē aʻe. Aia ʻo Tazemetostat i kahi papa o nā lāʻau i kapa ʻia nā mea kāohi EZH2. Kōkua ia e hōʻoki i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Tazemetostat ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i ʻelua mau manawa i ka lā me ka ʻai ʻole. E lawe i ka tazemetostat ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka tazemetostat e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā ʻoe e luaʻi koke ma hope o ka lawe ʻana i ka tazemetostat, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Kāohi paha kāu kauka i kahi manawa a kūloko paha i kāu lāʻau lapaʻau a hoʻoliʻiliʻi paha i kāu lāʻau o ka tazemetostat ma muli o nā hopena ʻaoʻao āu e ʻike ai. E kamaʻilio pono i kāu kauka e pili ana i kou ʻano i kou wā e mālama ai. Mai hōʻoki i ka lawe ʻana i ka tazemetostat me ka walaʻau ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka tazemetostat,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka tazemetostat, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa tazemetostat. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: aprepitant (Emend), carbamazepine (Carbatrol, Teril, a me nā mea ʻē aʻe), clarithromycin (Biaxin, ma Prevpac), diltiazem (Cardizem, Cartia, Diltzac, a me nā mea ʻē aʻe), efavirenz (Sustiva, i Atripla), erythromycin (EES, PCE, a me nā mea ʻē aʻe), nā mea pale hormonal (nā lāʻau kaohi hānau, nā pāliki, nā apo, a i ʻole nā ​​injection), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole, modafinil (Provigil), nefazodone, nelfinavir (Viracept), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, i Rifamate), ritonavir (Norvir, ma Kaletra), saquinavir (Fortovase, Invirase), a me verapma , Verelan). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me tazemetostat, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hoʻolālā i ka makua kāne o kahi keiki. Hoʻopilikia paha ʻo Tazemetostat i ka hana o nā mea pale hormonal (nā lāʻau kaohi hānau, nā pāhoʻi, nā apo, nā implants, a i ʻole nā ​​injection), no laila ʻaʻole pono ʻoe e hoʻohana i kēia mau mea ma ke ʻano he ʻano hana wale no kou kaohi hānau i kāu wā lapaʻau. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o ka hoʻomaka ʻana o ka mālama ʻana a hoʻohana i kahi kaohi hānau ʻole hormonal (kahi mea e ālai ana i ka sperm mai ke komo ʻana i ka uterus e like me ka condom) e pale ai i ka hāpai ʻana i kāu wā mālama a no 6 mau mahina ma hope o kāu lāʻau hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau kūpono i kou wā e mālama ai a no 3 mau mahina ma hope o kāu hopena hope loa. E noi i kāu kauka e kōkua iā ʻoe e koho i kahi hana o ka kaohi hānau e holo pono iā ʻoe a i ʻole kāu hoa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i ka tazemetostat, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Tazemetostat i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana a no 1 mau pule ma hope o kāu hopena hope loa.

Mai ʻai i ka nui o ka huaʻulu a inu paha i ka wai huaʻikuʻi i ka wā e lawe ana i kēia lāʻau.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Tazemetostat i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nalo ʻai ʻole
• nausea
• ka luaʻi
• kōpaʻa
• pāhoehoe
• ʻeha ka ʻōpū
• Kaumaha emi
• ʻūhā
• ʻeha poʻo
• luhi
• ʻeha, iwi, a ʻeha pū paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• luhi, palu maʻalahi, kuni, ʻeha iwi, a ʻili ʻulaʻula
• kahe koko ʻole ʻana
• maʻi maʻi ʻili
• pokole o ka hanu

Hiki i ka Tazemetostat ke hoʻonui i ka makaʻu o ka ulu ʻana i ka maʻi ʻaʻai. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Tazemetostat i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. No kekahi mau kūlana, e kauoha kāu kauka i kahi hoʻokolohua hoʻokolohua ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me tazemetostat. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka tazemetostat.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Tazverik^®