Zanubrutinib

Anter

• Ma mua o ka lawe ʻana i ka zanubrutinib,
• Hoʻokumu paha ʻo Zanubrutinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Zanubrutinib e mālama i ka limle cell lymphoma (MCL; kahi maʻi ʻaʻai e ulu wikiwiki ana e hoʻomaka i nā hunaola o ka ʻōnaehana pale) i nā mākua i mālama mua ʻia me hoʻokahi lāʻau chemotherapy ʻē aʻe. Aia ʻo Zanubrutinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Zanubrutinib ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ia hoʻokahi a ʻelua paha mau lā i kēlā me kēia me ka ʻole o ka meaʻai. Lawe iā zanubrutinib ma kahi o ka manawa like (s) i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka zanubrutinib pololei e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻopau piha i nā capsule me ke kīʻaha wai; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau, a hoʻopau paha a hoʻopau paha i kāu lāʻau. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ka zanubrutinib inā ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka zanubrutinib me ka ʻole o ke kamaʻilio ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka zanubrutinib,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka zanubrutinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule zanubrutinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: nā lāʻau anticoagulant ('nā mea hōʻemi koko') e like me warfarin (Coumadin, Jantoven); nā antifungals e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), a i ʻole ketoconazole; aprepitant (Cinvanti, Emend); clarithromycin (Biaxin, i Prevpac); digoxin (Lanoxin); diltiazem (Cardizem, Cartia, Tiazac, nā mea ʻē aʻe); erythromycin (E.E.S., Erythrocin, nā mea ʻē aʻe); kekahi mau lāʻau e mālama ai i ka maʻi pale maʻi kanaka (HIV) a i ʻole loaʻa i ka maʻi maʻi maʻi maʻi (AIDS) e like me efavirenz (Sustiva, i Atripla), nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra), a me saquinavir (Invirase); nefazodone; omeprazole (Prilosec); phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos); rifampin (Rifadin, Rifamate, Rimactane, nā mea ʻē aʻe); midazolam; a me nā steroid oral e like me dexamethasone, methylprednisolone (Medrol), a me prednisone (Rayos). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort.
• e haʻi i kāu kauka inā loaʻa ʻoe i kahi maʻi a i ʻole ʻokiʻoki hou ʻia. E haʻi pū aku i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha i kahi puʻuwai kīnā ʻole, ke koko kiʻekiʻe, nā pilikia kahe ʻana, a i ʻole ka maʻi puʻuwai a i ʻole ate.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i ka hānau keiki ʻana. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka zanubrutinib. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau a pono e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 1 pule ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau i ka wā o kāu mālama ʻana me zanubrutinib a hoʻomau no 1 pule ma hope o kāu hopena hope loa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka wā e lawe ana i ka zanubrutinib, e kāhea koke i kāu kauka. Hiki i ka Zanubrutinib ke hōʻeha i ka fetal.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana. Mai hānai i ka wā e lawe ana ʻoe i ka zanubrutinib a no 2 mau pule ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho e lawe nei ʻoe i ka zanubrutinib. E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka zanubrutinib no kekahi manawa ma mua a ma hope o ke ʻoki a me ke kaʻina hana.
• e hoʻolālā e hōʻalo i ka hōʻike kūpono ʻole a hoʻolōʻihi ʻia paha i ka lā a komo i nā lole pale, nā aniani aniani, a me ka sunscreen. Hiki iā Zanubrutinib ke hana i kou ʻili i ka hopena weliweli o ka lā, a hoʻonui i kou makaʻu i ka ulu ʻana i ka maʻi ʻaʻai ʻili.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.

Lawe i ka mahele lāʻau i hala ke hoʻomanaʻo ʻoe ia lā a hoʻomau i kāu papa hana maʻamau i ka lā aʻe. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Zanubrutinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• kōpaʻa
• ʻūhā
• Muscle, ami, a ʻeha hoʻi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• fiva, ʻeha ka ʻāʻī, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ʻeha, pinepine, a i ʻole urination urinary
• ʻū, ka pōkole o ka hanu, ʻeha ka umauma ke hanu ʻoe a i ʻole ka pi, a i ʻole ke kuni
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• ke koko i loko o kāu mau noho a ʻeleʻele paha, noho lōʻihi; mimi ʻulaʻula a ʻeleʻele paha; ka luaʻi ʻana i ke koko a i ʻole ka luaʻi kope lepo; kahe ana ke koko
• luʻuluʻu, nāwaliwali, a huikau paha; nā hoʻololi i ka ʻōlelo; ʻeha ke poʻo i lōʻihi loa
• hūwī
• ka wikiwiki a me ke kuʻi ʻole o ka puʻuwai, palpitations, ka uila a i ʻole ka puʻupuʻu, maʻule, pōkole o ka hanu, ʻeha o ka umauma.

Hiki i ka Zanubrutinib ke hoʻonui i kou makaʻu i ka hoʻomohala ʻana i kekahi ʻano maʻi ʻaʻai e like me ka maʻi ʻaʻai ʻili. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i ka zanubrutinib.

Hoʻokumu paha ʻo Zanubrutinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā zanubrutinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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