ʻO Baricitinib

Anter

• Ma mua o ka lawe baricitinib,
• Hoʻokumu paha ʻo Baricitinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

Ke hoʻopaʻa ʻia nei ʻo Baricitinib no ka mālama ʻana i ka maʻi coronavirus 2019 (COVID-19) me ka remdesivir (Veklury). Ua ʻae ka FDA i kahi ʻĀpana Hoʻohana Pilikia (EUA) e ʻae ai i ka hāʻawi ʻana i ka baricitinib e mālama i kekahi mau mākua a me nā keiki he 2 mau makahiki a ʻoi paha i hōʻola ʻia me ka maʻi COVID-19.

Lawe paha ka baricitinib i kou hiki ke hakakā i ka maʻi a hoʻonui i ka makaʻu e loaʻa ʻoe i kahi maʻi koʻikoʻi, e like me ka maʻi fungal, bacterial, a me nā maʻi viral i hoʻolaha ʻia i loko o ke kino. Pono e mālama ʻia kēia mau maʻi i ka haukapila a make paha ka make. E haʻi i kāu kauka inā loaʻa pinepine ʻoe i kekahi ʻano maʻi a i ʻole inā manaʻo ʻoe he ʻano maʻi paha kāu i kēia manawa. Hoʻopili kēia i nā maʻi liʻiliʻi (e like me nā ʻoki hāmama a i ʻole nā ​​ʻeha), nā maʻi i hiki a hele (e like me nā ʻeha anu), a me nā maʻi maʻi ʻole e hele. E haʻi i kāu kauka inā lawe ʻoe i nā lāʻau e hōʻemi i ka hana o ka ʻōnaehana pale pale e like me kēia: abatacept (Orencia); adalimumab (Humira); azathioprine (Azasan, Imuran); certolizumab pegol (Cimzia); cyclosporine (Gengraf, Neoral, Sandimmune); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); leflunomide (Arava); methotrexate (Otrexup; Rasuvo, Trexall); rituximab (Rituxan); sarilumab (Kevzara); steroid pū me dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), a me prednisone (Rayos); tocilizumab (Actemra); a me tofacitinib (Xeljanz).

E nānā ana kāu kauka iā ʻoe no nā hōʻailona o ka maʻi i ka wā a ma hope o kāu hoʻoponopono ʻana. Inā loaʻa iā ʻoe kekahi o nā ʻōuli aʻe ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau a i ʻole inā ʻike ʻoe i kekahi o nā ʻōuli ma hope a i ʻole ma hope koke paha o kāu lapaʻau ʻana, e kāhea koke i kāu kauka: fever; kāhili; haʻalulu; ʻeha ka ʻili; uā; pokole o ka hanu; Kaumaha emi; mahana, ʻulaʻula, a ʻeha ʻeha paha; ʻeha ma ka ʻili; pinepine, ʻeha, a wela paha ka manaʻo i ka wā o ka urination; diarrhea, a i ʻole ka luhi nui.

Ua hele a maʻi paha ʻoe i ka maʻi palupalu (TB; kahi maʻi puʻuwai koʻikoʻi) akā ʻaʻole i loaʻa nā ʻōuli o ka maʻi. I kēia hihia, ʻo ka lawe ʻana i ka baricitinib i mea e ʻoi aku ai ke koʻikoʻi i kou maʻi a hoʻomohala iā ʻoe i nā ʻōuli. E hana ana kāu kauka i kahi hoʻāʻo ʻili e ʻike inā loaʻa ʻole ʻoe i ka maʻi TB i hana ʻole ma mua a i kou wā o ka mālama ʻana me baricitinib. Inā pono, e hāʻawi aku kāu kauka iā ʻoe i ka lāʻau e mālama ai i kēia maʻi ma mua o kou hoʻomaka ʻana i ka baricitinib. E haʻi i kāu kauka inā loaʻa paha iā ʻoe ka TB, inā ua noho ʻoe a kipa paha i kahi ʻāina e maʻa mau ai ka TB, a inā ua puni ʻoe i kekahi me ka TB. Inā loaʻa iā ʻoe kekahi o nā ʻōuli o TB, a i ʻole inā hoʻomōhala ʻoe i kekahi o kēia mau ʻōuli i kou wā e lapaʻau ai, e kāhea koke aku i kāu kauka: batukū, ʻūʻē ʻana i nā aʻa koko, ka pohō kaumaha, ka nalowale ʻana o ke kani o nā mākala, a me ke kuni.

Lawe paha ka baricitinib i ka makaʻu e hoʻomohala ʻoe i kahi lymphoma (maʻi ʻaʻai e hoʻomaka i nā hunaola e hakakā i ka maʻi maʻi) a i ʻole nā ​​ʻano ʻē aʻe. E haʻi i kāu kauka inā loaʻa iā ʻoe a ua loaʻa paha iā ʻoe kekahi ʻano maʻi ʻaʻai.

Hiki paha i ka Baricitinib ke hoʻonui i ka makaʻu o ke kūpikipiki koko a weliweli paha i ke ola i nā akemāmā a me nā wāwae. Inā ʻoe e ʻike i kekahi o nā hopena aʻe, e kāhea i kāu kauka a i ʻole e kiʻi koke i ka lāʻau lapaʻau pōpilikia: ka ʻeha ʻana i ka ʻeha o ka umauma a i ʻole ka kaumaha o ka umauma. pokole o ka hanu; uā; ʻeha, mehana, ʻulaʻula, pehu, a palupalu wāwae paha; aiʻole ke anuanu i nā lima, nā lima, a i ʻole nā ​​wāwae; a ʻeha ʻeha paha.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua e nānā i ka pane o kou kino i ka baricitinib.

E kamaʻilio i kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka baricitinib.

Hoʻohana hoʻokahi ʻia ʻo Baricitinib a i ʻole me nā lāʻau ʻē aʻe e mālama ai i ka rheumatoid arthritis (ke ʻano e hoʻouka ai ke kino i kāna mau hui ponoʻī e hōʻeha ai i ka ʻeha, ka pehu ʻana, a me ka nalo ʻana o ka hana) i nā mākua i pane maikaʻi ʻole i hoʻokahi a ʻoi aku paha o ka tumrosis factor (TNF) mea kāohi. lāʻau (s). Aia ʻo Baricitinib i kahi papa o nā lāʻau i kapa ʻia ʻo Janus kinase (JAK) mea kāohi. Hana ia ma ka hoʻemi ʻana i ka hana o ka ʻōnaehana pale.

Hele mai ʻo Baricitinib ma ke ʻano he papa e lawe ma ka waha. Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. Lawe iā baricitinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka baricitinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Pono paha kāu kauka e hoʻopau i kahi manawa a kūloko paha i ka lāʻau lapaʻau inā ʻike ʻoe i kekahi hopena ʻino loa. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe baricitinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka baricitinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa baricitinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E kuhikuhi pono i nā lāʻau i helu ʻia i ka ʻĀINA AOAO PAHU a i ʻole ka mea aʻe: probenecid (Probalan, ma Col-Probenecid). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe ka ʻeha o ka ʻōpū i hōʻike ʻole ʻia a i ʻole inā loaʻa a loaʻa paha ʻoe i ka diverticulitis (ka pehu ʻana o ka uhi o ka ʻōpū nui), anemia, herpes zoster (shingles; kahi ʻāwīwī e hiki mai i ka poʻe i loaʻa ka moa moa i ka wā i hala), a i ʻole ka ate a i ʻole nā ​​maʻi puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā hāpai ʻoe i ka lawe ʻana i ka baricitinib, e kāhea i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. Mai hānai i ka wā e lawe ana i ka baricitinib.
• e haʻi i kāu kauka inā loaʻa iā ʻoe i kēia manawa a i ʻole e hoʻolālā ʻia e loaʻa nā lāʻau āpau. ʻAʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana me ke kamaʻilio ʻole ʻana me kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Baricitinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• abdominal eha
• loli ka ʻōpū

Hoʻokumu paha ʻo Baricitinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

Ma mua o ka loaʻa ʻana o kahi hoʻokolohua hoʻokolohua, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua āu e lawe nei i ka baricitinib.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Olumiant^®