ʻO Cabozantinib (ke akepaʻa a me ke kanesa maʻi ʻaʻai)

Anter

• Ma mua o ka lawe ʻana i cabozantinib (Cabometyx),
• ʻO Cabozantinib (Cabometyx) ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana ʻia ʻo Cabozantinib (Cabometyx) e mālama i ka carcinoma kōkō ʻoi loa (RCC; kahi ʻano maʻi ʻaʻai e hoʻomaka i nā hunaola o nā puʻupaʻa). Hoʻohana pū ʻia me ka nivolumab (Opdivo) e mālama i ka RCC holomua i nā mea maʻi i loaʻa ʻole ka lāʻau no RCC. Hoʻohana pū ʻia ʻo Cabozantinib (Cabometyx) e mālama i ka maʻi maʻi hepatocellular (HCC; kahi ʻano maʻi ʻaʻai ate) i ka poʻe i mālama mua ʻia me sorafenib (Nexafar). Aia ʻo Cabozantinib (Cabometyx) i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Loaʻa ʻo Cabozantinib ma ke ʻano he capsule (Cometriq) e mālama i kekahi ʻano o ka maʻi ʻaʻai thyroid. Hāʻawi wale kēia monograf i ka ʻike e pili ana i nā papa cabozantinib (Cabometyx) no RCC kiʻekiʻe a i ʻole HCC. Inā ʻoe e hoʻohana ana i kēia lāʻau no ka maʻi ʻaʻai thyroid, e heluhelu i ka monograph i kapa ʻia ʻo cabozantinib (ka maʻi ʻaʻai thyroid).

Hele mai ʻo Cabozantinib (Cabometyx) ma ke ʻano he papa e lawe ʻia e ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā ma ka ʻōpū hakahaka, ma ka liʻiliʻi he 1 hola ma mua a me 2 mau hola ma hope o ka ʻai ʻana. Lawe iā cabozantinib (Cabometyx) ma kahi o ka manawa like i kēlā me kēia lā. Aia ka lōʻihi o kāu mālama ʻana i ka maikaʻi o ka pane ʻana o kou kino i ka lāʻau a me nā hopena ʻaoʻao āu e ʻike ai. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka cabozantinib (Cabometyx) e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa āpau me ke kīʻaha piha (8 auneke, 240 mL) o ka wai. Mai hoʻokaʻawale, a nau, a ʻāpala paha iā lākou.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o cabozantinib (Cabometyx) a i ʻole kūmau manawa a kūloko paha i kāu lāʻau inā ʻike ʻoe i nā hopena ʻino. E kamaʻilio pono i kāu kauka e pili ana i kou ʻano e mālama ai me ka cabozantinib (Cabometyx).

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i cabozantinib (Cabometyx),

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka cabozantinib (Cabometyx, Cometriq), i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa cabozantinib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea lapaʻau i ka lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihapiha, lawe ʻoe a hoʻolālā paha e lawe E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: boceprevir (Victrelis), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), clarithromycin (Biaxin, i Prevpac), conivaptan (Vaprisol), indinavir (Crixivan), itraconazole (Onmel, Spam ), ketoconazole, nefazodone, nelfinavir (Viracept), phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, in Rifamate, Rifater), rifapentine (Prift) , ma Kaletra), saquinavir (Invirase), telithromycin (Ketek), a me voriconazole (Vfend). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me cabozantinib (Cabometyx), no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi aku i kāu kauka inā he lua ʻole kou a he koko koko ʻē aʻe paha e like me ke kūkae ʻana i ke koko, ka luaʻi ʻana i ke koko, a i ʻole nā ​​kūpeʻa koko a ʻeleʻele paha, inā he ʻeha hāmama a hoʻōla paha ʻoe, a inā he kaʻe koko kiʻekiʻe kou, aiʻole ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe i kahi hōʻoia hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau me cabozantinib. ʻAʻole ʻoe e hāpai i ka wā o kāu lapaʻau a no 4 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka lawe ʻana iā cabozantinib (Cabometyx), e kāhea koke i kāu kauka. Hiki paha iā Cabozantinib ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hānai i ka waiū i kāu wā e mālama ai a no 4 mau mahina ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i cabozantinib (Cabometyx).
• inā ke hana ʻoki ʻia ʻoe e haʻi i ke kauka e lawe nei ʻoe iā cabozantinib (Cabometyx). E haʻi paha kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka cabozantinib (Cabometyx) ma ka liʻiliʻi he 21 mau lā ma mua o kou ʻoki ʻana a i ʻole ke kaʻina hana, a e haʻi wau iā ʻoe ke hoʻomaka hou ʻoe e lawe i ka lāʻau.
• pono ʻoe e ʻike ʻo ka cabozantinib (Cabometyx) ke kumu o nā pilikia koʻikoʻi me kou aʻa. Pono kahi kauka niho e nānā i kou mau niho ma mua o ka hoʻomaka ʻana e lawe i ka cabozantinib a maʻa mau i kāu wā e lapaʻau ai. E nānā pono e palaki i kou mau niho a hoʻomaʻemaʻe i kou waha pono ʻoiai ʻoe e lawe nei i ka cabozantinib (Cabometyx). E kamaʻilio me kāu kauka ma mua o ka loaʻa ʻana o nā lāʻau lapaʻau iā ʻoe e lawe nei i kēia lāʻau. E haʻi paha kāu kauka iā ʻoe e hōʻoki i ka lawe ʻana i ka cabozantinib ma ka liʻiliʻi he 21 mau lā ma mua o ke kauka niho.
• pono ʻoe e ʻike e hoʻonui paha kou kahe koko i kou wā e mālama ai me cabozantinib. E nānā paha kāu kauka i kou kaomi koko ma mua a i kou wā o ka mālama ʻana.

Mai inu i ka wai huaʻikuʻu a ʻai paha i ka huaʻulu a i ʻole nā ​​meaʻai a i ʻole nā ​​mea hoʻopihapiha i loaʻa ka huaʻulu a i ʻole ka wai momona i ka wā e lawe nei ʻoe i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā he emi ia ma mua o 12 mau hola a hiki i kāu kau palena hope e hoʻolālā ʻia, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

ʻO Cabozantinib (Cabometyx) ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kōpaʻa
• nausea
• ka luaʻi
• hoʻololi i ka hiki ke ʻono i ka meaʻai
• ʻulaʻula, pehu, ʻeha, a ʻeha paha i kou waha
• nalo ʻai ʻole
• Kaumaha emi
• ka luhi nui a nawaliwali paha
• ʻili mae
• ʻili maloʻo
• spasm Muscle
• ʻeha ma nā hono, nā lima, a me nā wāwae
• hoʻololi a leo paha ka leo
• hoʻōla hoʻōla hōʻeha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• ʻeha o ka umauma, kaomi, a i ʻole ka paʻa
• ke kuʻi nei i ke koko a i ʻole ke koko
• luaʻi i nā mea koko a ʻano like paha me nā papa kope
• kahe keu o ke kāne ma mua o ka maʻamau
• ʻulaʻula a ʻeleʻele paha, noho aliʻi
• pāhoehoe
• ʻokoʻa a kaumaha paha ke kahe ʻana a i ʻole ʻūpā
• palapū a ʻeha paha i ka ʻōpū
• mehana, ʻulaʻula, pehu, a palupalu paha nā lima a mau wāwae paha
• pehu a puni nā maka, nā lima, nā lima, nā wāwae, nā wāwae, a me nā kuʻekuʻe wāwae
• mimi hu
• pōkole o ka hanu a me ke kahe
• ʻeha poʻo poʻo
• ʻālohilohi a maʻule paha
• ka hopu ʻana
• numbness a nāwaliwali paha o ka maka, ka lima, a me ka wāwae ma kekahi ʻaoʻao o kou kino
• pilikia pilikia hele wāwae
• pilikia pilikia hikiwawe
• huikau
• paʻakikī paʻakikī e noʻonoʻo a ʻōlelo ʻana paha
• pilikia paʻakikī me ke kaulike a me ka hoʻohui ʻana
• ʻūpā
• sweating ʻoi aku ma mua o ka maʻamau
• ʻeha ka ʻāʻī
• ʻeha ʻeha
• ka hemo ʻana o nā niho
• gums pehu a ʻeha hoʻi
• hūwī
• ʻulaʻula, ʻeha, ʻōhū, a i ʻole pāhuna ma nā palma a me nā kapuwaʻi
• māluhiluhi loa, hoʻoluhi, maʻule, nāwaliwali, nausea, a i ʻole ka luaʻi
• melemele o ka ʻili a i ʻole nā ​​maka, māluhiluhi nui loa, kahe ʻana o ke kōkō a palū paha paha, pākī a luaʻi paha, ʻeha o ka ʻōpū ʻaoʻao ʻākau, mimiki ʻeleʻele, hoʻemi i ka makemake.

Hiki iā Cabozantinib (Cabometyx) ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• poho hoʻomanaʻo
• huikau
• Kaumaha emi

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā cabozantinib (Cabometyx).

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Cabometyx^®