ʻAkika Obeticholic

Anter

• Ma mua o ka lawe ʻana i ka waikawa obeticholic,
• Hiki i ka Obeticholic acid ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hiki i ka Obeticholic acid ke kumu i ka hōʻino o ke ake a weliweli paha i ke ola, keu hoʻi inā ʻaʻole hoʻoponopono ʻia ka lāʻau o ka obeticholic acid i ka wā e maʻi ai ka maʻi ate. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope ke lawe nei ʻoe i ka waikawa obeticholic, e kāhea koke i kāu kauka: melemele o ka ʻili a i ʻole nā ​​maka, ʻeleʻele ʻeleʻele, noho pāleʻele ʻeleʻele, ʻūlū ʻana a i ʻole ke luaʻi nei paha i ke koko, nausea, ka luaʻi, ʻeha o ka ʻōpū, puhū a puni ka ʻāpana o ka ʻōpū, hoʻemi kaupaona, nalowale o ka makemake, luhi, diarrhea, huikau, ʻōlelo kūmau, hopohopo, hoʻololi i ke ʻano, nā loli i ke ʻano, a i ʻole ka urination pinepine ʻole.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Hiki paha i kāu kauka ke kauoha i kekahi mau hoʻokolohua ma mua a i kou wā e mālama ai e nānā i kāu hana ate a me ka pane o kou kino i ka obeticholic acid.

Hoʻohana wale ʻia ʻo Obeticholic acid a i ʻole hui pū ʻia me ursodiol (Actigall, Urso) e mālama i ka cholangitis biliary mua (PBC; kahi ʻano o ka maʻi ate e luku i nā aʻa o ka bile, e ʻae ai ka bile e noho i ke akepaʻa a hoʻopōʻino) i ka poʻe hiki ʻole ke lawe ursodiol a i ʻole i ka poʻe i mālama ʻole ʻia me ursodiol wale nō. ʻO ka Obeticholic acid i loko o ka papa o nā lāʻau i kapa ʻia nā agonists reseptor farnesoid X. Hana ia ma ka hoʻemi ʻana i ka hana o ka bile i ke akepaʻa a me ka hoʻonui ʻana i ka lawe ʻana o ka bile mai ke ake.

Hele mai ka Obeticholic acid ma kahi papaha e lawe ʻia e ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka ʻai ʻole. E lawe i ka waikawa obeticholic ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka waikawa obeticholic e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Pono paha kāu kauka e hoʻopau i kahi manawa a kūloko paha i kāu lāʻau lapaʻau a hoʻoliʻiliʻi paha i kāu lāʻau o ka obeticholic acid i kāu wā e lapaʻau ai. E pili kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a i ʻole inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E hoʻomau i ka lawe ʻana i ka waikawa obeticholic inā ʻoe e manaʻo maikaʻi. Mai hōʻoki i ka lawe ʻana i ka waikawa obeticholic me ka walaʻau ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka waikawa obeticholic,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka waikawa obeticholic, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i nā papa acid obeticholic. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E mālama pono i kekahi o kēia mau mea: caffeine (i loaʻa i kekahi mau lāʻau e mālama ai i ka hiamoe a me nā ʻeha poʻo poʻo), theophylline (Elixophyllin, Theo-24, Theochron, a me nā mea ʻē aʻe), tizanidine (Zanaflex), a i ʻole warfarin (Coumadin, Jantoven). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Pili pū paha nā lāʻau ʻē aʻe he nui me ka waikawa obeticholic, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• inā ʻoe e lawe nei i ka cholestyramine (Prevalite), colestipol (Colestid), a i ʻole colesevelam (Welchol), e lawe iā lākou ma kahi o 4 mau hola ma mua a i ʻole 4 mau hola ma hope o ka obeticholic acid.
• e haʻi i kāu kauka inā loaʻa iā ʻoe ke kahakaha o ka bile (blockage i nā paipu e lawe i ka bile mai ke ake a i ka gallbladder a me ka ʻōpū liʻiliʻi). E haʻi paha kāu kauka iā ʻoe mai lawe i ka waikawa obeticholic.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa iā ʻoe kahi kolesterol kiʻekiʻe a i ʻole he maʻi thyroid.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka waikawa obeticholic, e kāhea i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Obeticholic acid ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha ka waha a ʻeha paha
• wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
• hūwī
• ʻūpā
• maule ana
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• nāwaliwali a nāwaliwali paha
• ʻeha hui a ʻeha ʻeha paha
• kōpaʻa

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻ sectionlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka:

• ʻume mākala nui
• ke kuni, ke anu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ka maloʻo, hoʻonāukiuki, ʻulaʻula, kalehu a i ʻole ka hoʻokahe ʻana o ka ʻili

Hiki i ka Obeticholic acid ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• melemele o ka ʻili a me nā maka
• mimi kala ʻeleʻele
• nalo ʻai ʻole
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
• nausea
• ka luaʻi
• pehu i ka wahi a puni ka ʻōpū

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Ocaliva^®