ʻO Cobimetinib

Anter

• Ma mua o ka lawe ʻana i ka cobimetinib,
• Hoʻokumu paha ʻo Cobimetinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole kēlā mau mea i ka ʻĀKAHI MAKAHIKI ʻāpana, e kelepona koke i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia

Hoʻohana ʻia ʻo Cobimetinib me vemurafenib (Zelboraf) e mālama i kekahi ʻano melanoma (kahi ʻano maʻi ʻaʻai ʻili) ʻaʻole hiki ke mālama ʻia me ke ʻoki a i pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino. Aia ʻo Cobimetinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Cobimetinib ma ke ʻano he papa e lawe ma ka waha me ka ʻole o ka meaʻai. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā no nā lā 21 mua o kahi pōʻaiapuni 28 mau lā. E lawe i ka cobimetinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe i ka cobimetinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka cobimetinib mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o cobimetinib a i ʻole kūmau manawa a kūloko paha i kāu lāʻau. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E hoʻomaopopo pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me cobimetinib.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka cobimetinib,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka cobimetinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa cobimetinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: anticoagulants (nā mea lahilahi o ke koko) e like me warfarin (Coumadin, Jantoven), carbamazepine (Carbatrol, Epitol, Tegretol), ciprofloxacin (Cipro), clarithromycin (Biaxin, i Prevpac), efavirenz (Sustiva, i Atripla), erythromycin (EES, E-Mycin, Erythrocin), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Ketozole, Nizoral), nefazodone, nelfinavir (Viracept), phenytoinin (Dilantin, (Rifadin, Rimactane, ma Rifamate, ma Rifater), a me ritonavir (Norvir, ma Kaletra, ma Viekira Pak). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me cobimetinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort. Mai lawe iā St. John's Wort ʻoiai ʻoe e lawe nei i ka cobimetinib.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i nā ʻano ʻili ma mua o ka melanoma; nā pilikia koko; pilikia pilikia; nā kūlana e hoʻopili i kou mau mākala; aiʻole ka maʻi puʻuwai a i ʻole ate.
• pono ʻoe e ʻike i ka cobimetinib e hoʻemi i ka momona i nā kāne a me nā wahine. Eia nō naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe a i ʻole kāu pakanā ke hāpai. E haʻi i kāu kauka inā hāpai ʻoe a hoʻolālā paha e hāpai. E hoʻohana i kahi ʻano pono o ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā e mālama ai a no 2 mau pule ma hope o kou kū ʻana i ka lawe ʻana i ka cobimetinib. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i ka cobimetinib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Cobimetinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana i ka cobimetinib a no 2 mau pule ma hope o kāu hopena hope loa.
• hoʻolālā e hōʻalo i ka pono ʻole a hoʻolōʻihi ʻia paha i ka lā a komo i nā lole pale, nā aniani aniani, nā lehelehe lepe a me ka sunscreen (SPF 30 a ʻoi aku). Hoʻomaopopo paha ʻo Cobimetinib i kou ʻili i ka lā o ka lā.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Cobimetinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ulcer waha
• poho lauoho
• pāhoehoe

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole kēlā mau mea i ka ʻĀKAHI MAKAHIKI ʻāpana, e kelepona koke i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia

• hū e uhi ana i kahi ākea o kou kino, palapū, a i ʻole ʻili ihi
• hoʻololi i ka helehelena o ka ʻili
• wart hou
• ʻeha ka ʻili a ʻulaʻula paha e hoʻokahe ke koko a hoʻōla ʻole paha
• e hoʻololi i ka nui a me ke kala o kahi mole
• kahe koko ʻole ʻana a palapū paha
• noho mālie a i ʻole noho ʻeleʻele
• koko i ka mimi
• hoʻokahe keu
• ʻeha poʻo
• ʻūpā
• wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
• ʻū a ʻūhā paha
• pokole o ka hanu
• ka pehu o ka maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae
• luhi
• ʻehaʻeha a nāwaliwali paha
• loli i ka hihiʻo, me ke ʻike ʻana i ka ʻaneʻane (kahakaha pōuliuli a puni nā mea)
• melemele o ka ʻili a me nā maka
• mimi ʻeleʻele
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
• nausea
• ka luaʻi
• nalo ʻai ʻole

Hiki i ka Cobimetinib ke hoʻonui i ka makaʻu e hoʻomohala ʻoe i nā maʻi ʻili ʻili hou. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Cobimetinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka wā a ma hope o ka lāʻau. E nānā kāu kauka i kou ʻili no nā loli ma mua, i kēlā me kēia 2 mau mahina i kou wā e hoʻomaʻamaʻa ai, a hiki i 6 mau mahina ma hope o ka lapaʻau.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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