ʻO Dimethyl Fumarate

Anter

• Ma mua o ka lawe ʻana i ka dimethyl fumarate,
• Hoʻokumu ʻo Dimethyl fumarate i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka dimethyl fumarate a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Dimethyl fumarate e mālama i nā mākua me nā ʻano like ʻole o ka sclerosis maha (MS; kahi maʻi kahi e holo pono ʻole ai nā ʻalalā a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka hoʻohui ʻana o nā mākala, a me nā pilikia me ka hihiʻo, ka ʻōlelo, a me ka mālama ʻana i ka maʻi ʻaʻa) me:

• maʻi hoʻokaʻawale clinically (CIS; nā ʻōuli ʻōuli nerve e kū ma ka liʻiliʻi he 24 mau hola),
• relapsing-remitting forms (papa o ka maʻi kahi e ʻō ai nā ʻōuli mai kēlā me kēia manawa), a i ʻole
• nā papa holomua holomua (papa o ka maʻi kahi e hoʻi pinepine ai ka hoʻi ʻana).

ʻO Dimethyl fumarate i loko o kahi papa o nā lāʻau i kapa ʻia ʻo Nrf2 activators. Hana ia ma ka hōʻemi ʻana i ka lī a me ka pale ʻana i nā hōʻino o ke aʻalolo e kumu ai nā ʻōuli o ka sclerosis maha.

Hele mai ʻo Dimethyl fumarate ma ke ʻano he lohi-hoʻokuʻu (hoʻokuʻu i ka lāʻau i loko o ka ʻōpū e pale i ka haki ʻana o ka lāʻau e nā ʻōpū o ka ʻōpū) e lawe ka waha. Lawe ʻia ia i ʻelua mau manawa i ka lā. E lawe i ka dimethyl fumarate ma kahi o nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka dimethyl fumarate e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Hiki ke lawe ʻia ʻo Dimethyl fumarate me ka ʻole o ka meaʻai. Eia nō naʻe, inā ʻoe e lawe i ka dimethyl fumarate me ka meaʻai a i ʻole me kahi aspirin kapa komo ʻole ʻia (325 mg a ʻoi aku paha) 30 mau minuke ma mua o ka lawe ʻana i dimethyl fumarate, aia ka liʻiliʻi o ka manawa e ʻike ʻoe i ka pīpī i kāu wā e lapaʻau ai.

E ale i nā capsule holoʻokoʻa; mai nau, a naʻu hoʻi. Mai wehe i nā capsule a kāpīpī i ka ʻike i ka meaʻai.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o ka dimethyl fumarate a hoʻonui i kāu lāʻau ma hope o 7 mau lā.

Hiki i ka Dimethyl fumarate ke kōkua i ka mālama ʻana i nā sclerosis he nui, akā ʻaʻole ia e hoʻōla iā ia. E hoʻomau i ka lawe i ka dimethyl fumarate ʻoiai ʻoe e ʻoluʻolu. Mai hōʻoki i ka lawe ʻana i ka dimethyl fumarate me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Hoʻohana ʻia ʻo Dimethyl fumarate i kekahi manawa e mālama i ka psoriasis (kahi maʻi maʻi kahi e hana ai nā ʻulaʻula, scaly patch ma kekahi mau wahi o ke kino). E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka hoʻohana ʻana i kēia lāʻau no kou maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka dimethyl fumarate,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka dimethyl fumarate, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā capsule dimethyl fumarate. E noi i kāu kauka lāʻau a nānā paha i ka ʻike hoʻomanawanui o ka mea hana no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa kekahi ʻano maʻi, me nā maʻi e hele mai ana a hele aku a me nā maʻi kūlohelohe e hele ʻole, a i ʻole inā loaʻa paha iā ʻoe i ka ʻāpana moa a i ʻole herpes zoster (shingles; kahi ʻāwīwī e hiki i nā poʻe i loaʻa ua loaʻa ka paukū i ka wā i hala); a i ʻole helu helu keʻokeʻo haʻahaʻa keʻokeʻo.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka dimethyl fumarate, e kāhea i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu ʻo Dimethyl fumarate i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• mehana, ʻulaʻula, ʻili, a ʻaʻā paha o ka ʻili
• pāhoehoe
• nausea
• ka luaʻi
• puʻuwai puʻuwai

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka dimethyl fumarate a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pilikia i ka ale ʻana a me ka hanu ʻana
• ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• hives
• hūwī
• ʻūlili
• hulahula
• pilikia pilikia ʻike
• nāwaliwali ma kekahi ʻaoʻao o ke kino a i ʻole clumsiness o nā lima a i ʻole nā ​​wāwae e ʻino ai i ka hala ʻana o ka manawa
• nā hoʻololi i ka hihiʻo
• nā hoʻololi i kou noʻonoʻo, hoʻomanaʻo, a ʻike paha e alakaʻi i ka huikau a me nā ʻano pilikino
• ka luhi nui loa, nalo o ka makemake ʻole, ʻeha ma ka ʻaoʻao ʻākau i luna o kou ʻōpū, mimi ʻeleʻele, a melemele o ka ʻili a me nā maka
• nāwaliwali ma kekahi ʻaoʻao o ke kino e ʻino ana i ka hala ʻana o ka manawa; clumsiness o nā lima a mau wāwae paha; nā hoʻololi i kou noʻonoʻo, hoʻomanaʻo, hele wāwae, kaulike, ʻōlelo, ʻike maka, a i ʻole ikaika i hala i mau lā; ʻeha poʻo poʻo; ka hopu ʻana; huikau; a i ʻole hoʻololi i ke ʻano
• puhi, ʻalalā, ʻili, a me ka ʻili o ka ʻili ma kekahi ʻaoʻao o ke kino a i ʻole ke alo me ka ʻeha a ʻeha paha i hōʻike ʻia i kekahi mau lā ma hope.

ʻO Dimethyl fumarate ke kumu o nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a mamao aku mai ka mālamalama, ka wela a me ka momona o ka wela (ʻaʻole i loko o ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Hiki i kāu kauka ke kauoha i kahi hoʻokolohua koko ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau a kauoha paha i kekahi mau hoʻokolohua lab i kou wā e mālama ai e nānā i ka pane o kou kino i dimethyl fumarate.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Tecfidera^®

• DMF