ʻO Ivacaftor

Anter

• Ma mua o ka lawe ʻana i ivacaftor,
• Hana ʻo Ivacaftor i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana ʻia ʻo Ivacaftor e mālama i kekahi ʻano o ka cystic fibrosis (kahi maʻi i loko e pilikia ai ka hanu ʻana, ka ʻai ʻana, a me ka hana hou ʻana) i nā mākua a me nā keiki he 4 mau makahiki a ʻoi paha. Pono e hoʻohana ʻia ʻo Ivacaftor i nā poʻe wale nō me kahi make-up. Kauoha paha kāu kauka i kahi hoʻokolohua koko e kōkua ai e hoʻoholo inā kūpono kēia lāʻau iā ʻoe. Aia ʻo Ivacaftor i kahi papa o nā lāʻau i kapa ʻia he cystic fibrosis transmembrane conductance regulator (CFTR) potentiators. Hana ia ma ka hoʻomaikaʻi ʻana i ka hana o kahi protein i loko o ke kino e hōʻemi i ke kūkulu ʻana o nā mucus mānoanoa i nā akemāmā a me ka hoʻomaikaʻi ʻana i nā ʻōuli ʻē aʻe o ka cystic fibrosis.

Hele mai ʻo Ivacaftor ma ke ʻano he papa a me nā granula e lawe ma ka waha. Lawe pinepine ʻia me nā meaʻai momona i ʻelua mau manawa i ka lā, 12 mau hola ke kaʻawale. Lawe i ka ivacaftor ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka ivacaftor e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻomākaukau i kahi mahele o nā granula ivacaftor, e kāwili i ka piha piha o nā granula i 1 teaspoon (5 mL) o ke anuanu a i ʻole ke ana wela o ka meaʻai a wai paha e like me yogurt, applesauce, wai, waiū, pēpē pēpē, waiū umauma, a wai wai paha. Lawe i ka hui ʻana ma loko o 1 hola o ka hoʻohuihui ʻana i nā granula me ka meaʻai a i ʻole kahi wai.

Lawe i kēlā me kēia mahele o ka ivacaftor me kahi mea momona momona e like me nā hua, ka bata, ka wai pīnī, ka waiū tī, nā huahana waiū waiū holoʻokoʻa (e like me ka waiū piha, ka tī, a me ka yogurt), ka pēpē pēpē, a me ka waiū o ka waiū. E kamaʻilio me kāu kauka e pili ana i nā meaʻai momona ʻē aʻe e ʻai ai me ivacaftor.

Mālama ʻo Ivacaftor i ka cystic fibrosis akā ʻaʻole ia e hoʻōla iā ia. E hoʻomau i ka lawe ʻana i ka ivacaftor ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka ivacaftor me ka walaʻau ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ivacaftor,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka ivacaftor, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa ivacaftor. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, lawe ʻoe a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: kekahi antibiotic e like me clarithromycin (Biaxin, i PrevPac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), a me telithromycin (Ketek); kekahi mau antifungals e like me fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), a me voriconazole (Vfend); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); kekahi mau lāʻau no ka hopu ʻana e like me ka carbamazepine (Carbatrol, Epitol, Tegretol, a me nā mea ʻē aʻe), phenobarbital, a me phenytoin (Dilantin, Phenytek); midazolam; rifabutin (Mycobutin); rifampin (Rifadin, ma Rifamate, ma Rifater, Rimactane); tacrolimus (Astagraf, Prograf), a i ʻole warfarin (Coumadin, Jantoven). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka ivacaftor, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate a me nā puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka ivacaftor, kāhea i kāu kauka.
• pono ʻoe e ʻike i ka ivacaftor e hoʻohoka ai iā ʻoe. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.

Mai ʻai i ka huaʻikuʻi a i ʻole nā ​​ʻalani ʻo Seville a inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

Inā hoʻomanaʻo ʻoe i ka lāʻau i hala ma loko o 6 mau hola o ka manawa āu i hoʻonohonoho ʻia ai e lawe, lawe koke i ka lāʻau i hala me kahi meaʻai momona. Eia nō naʻe, inā ua hala ma mua o 6 mau hola mai ka manawa i hoʻopaʻa ʻia, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hana ʻo Ivacaftor i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• hūwī
• ʻeha pū
• ʻeha ka waha a me ka ʻāʻī
• fiva, ʻāʻī puʻupuʻu, ihu ihu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• pāhoehoe
• ʻūpā

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• nausea
• ka luaʻi
• nalo ʻai ʻole
• ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
• mimi ʻeleʻele
• luhi loa
• kahe koko ʻole ʻana a palapū paha
• melemele o ka ʻili a me nā maka
• loli ka hihiʻo

Hiki paha i ka Ivacaftor ke hoʻonui i ka makaʻu e hoʻomohala ai ʻoe a i ʻole kāu keiki i nā maʻi katarakō. E kamaʻilio me kāu kauka a i ʻole kauka a kāu keiki e pili ana i nā makaʻu o ka lawe ʻana i kēia lāʻau.

Hoʻokumu paha ʻo Ivacaftor i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• ʻūpā
• pāhoehoe

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kahi hoʻokolohua maka a me kekahi mau hoʻokolohua lab ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino iā ivacaftor.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Kalydeco^®