ʻO Boceprevir

Anter

• Ma mua o ka lawe ʻana i boceprevir,
• Hoʻokumu paha ʻo Boceprevir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Boceprevir me nā lāʻau ʻē aʻe ʻelua (ribavirin [Copegus, Rebetol] a me peginterferon alfa [Pegasys]) e mālama ai i ka maʻi hepa hepatitis C (kahi maʻi viral e hoʻomau nei e hōʻino ai i ke ake) i ka poʻe i mālama ʻole ʻia no kēia ʻano a i ʻole ʻaʻole i hoʻomaikaʻi ke ʻano ke mālama ʻia lākou me ribavirin a me peginterferon alfa wale nō. Aia ʻo Boceprevir i kahi papa o nā lāʻau i kapa ʻia nā protease inhibitors. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi hepitis C (HCV) i ke kino. ʻAʻole hiki iā Boceprevir ke pale i ka hoʻolaha ʻana o ka maʻi hepatitis C i kekahi poʻe ʻē aʻe.

Hele mai ʻo Boceprevir ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ʻia ia me kahi pāʻina a i ʻole nā ​​meaʻai māmā ʻekolu mau manawa i ka lā (i kēlā me kēia 7 a 9 mau hola). Lawe iā boceprevir ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka boceprevir. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E lawe ʻoe i ka peginterferon alfa a me ka ribavirin no 4 mau pule ma mua o kou hoʻomaka ʻana me ka boceprevir. A laila e lawe ʻoe i nā lāʻau ʻekolu āpau no 12 a 44 mau pule. Ma hope o kēia manawa, e hoʻōki ʻoe i ka lawe ʻana i ka boceprevir, akā hoʻomau paha ʻoe e lawe i ka peginterferon alfa a me ka ribavirin no kekahi mau pule hou aku. Pili ka lōʻihi o kāu lapaʻau i kou ʻano, pehea kou pane ʻana i ka lāʻau, a inā ʻoe e ʻike i nā hopena ʻino. E hoʻomau i ka lawe ʻana i ka boceprevir, peginterferon alfa, a me ka ribavirin ke lōʻihi ke kuhikuhi ʻia e kāu kauka. Mai hōʻoki i ka lawe ʻana i kekahi o kēia mau lāʻau me ke kamaʻilio ʻole ʻana me kāu kauka inā ʻoe ke olakino maikaʻi nei.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me boceprevir a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i boceprevir,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka boceprevir, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā capsule boceprevir. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā e lawe nei ʻoe i kekahi o nā lāʻau aʻe a i ʻole nā ​​huahana lāʻau: alfuzosin (Uroxatral); nā lāʻau lapaʻau ergot e like me dihydroergotamine (D.H.E. 45, Migranal), ergonovine, ergotamine (Ergomar, ma Cafergot, ma Migergot) a i ʻole methylergonovine; cisapride (Propulsid) (ʻaʻole loaʻa ma ka U.S.); drospirenone (i kekahi o nā mea pale waha e like me Beyaz, Gianvi, Ocella, Safyral, Yasmin, Yaz, a me Zarah); lovastatin (Altoprev, Mevacor); kekahi mau lāʻau no ka hopu ʻana e like me ka carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, a i ʻole phenytoin (Dilantin); lawe ʻia ka midazolam e ka waha; pimozide (Orap); rifampin (Rifadin, Rimactane, ma IsonaRif, ma Rifamate, ma Rifater); sildenafil (ʻo ka inoa Revatio wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); simvastatin (Simcor, ma Vytorin); tadalafil (ʻo ka brand Adcirca wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); St. John's wort; aiʻole triazolam (Halcion). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka boceprevir inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: alprazolam (Niravam, Xanax); anticoagulants ('blood thinners') e like me warfarin (Coumadin); nā lāʻau antifungal e like me itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), a me voriconazole (Vfend); atorvastatin (Lipitor, ma Caduet); bosentan (Tracleer); budesonide (Pulmicort, Rhinocort, Symbicort); buprenorphine (Buprenex, Butrans, Subutex, Suboxone); nā poloka kalipuna e like me felodipine (Plendil), nicardipine (Cardene), a me nifedipine (Adalat, Afeditab, Procardia); clarithromycin (Biaxin); colchisin (Colcrys, ma Col-Probenecid); cyclosporine (Gengraf, Neoral, Sandimmune); desipramine (Norpramin); dexamethasone; kekahi mau lāʻau no ka hana erectile e like me sildenafil (Viagra), tadalafil (Cialis), a me vardenafil (Levitra, Staxyn); kekahi mau lāʻau no ka HIV e like me atazanavir i lawe ʻia me ritonavir, darunavir i lawe ʻia me ritonavir, efavirenz (Sustiva, i Atripla), lopinavir i lawe ʻia me ritonavir, a me ritonavir (Norvir, ma Kaletra); kekahi mau lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Cordarone, Pacerone), digoxin (Lanoxin), flecainide (Tambocor), propafenone (Rythmol), a me quinidine; methadone (Dolophine, Methadose); hāʻawi 'ia' o intazolam i loko o ke aniani (i loko o kahi aa); rifabutin (Mycobutin); salmeterol (Serevent, ma Advair); sirolimus (Rapamune); tacrolimus (Prograf); a trazodone. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā ua loaʻa ʻoe i kahi transplant, a inā loaʻa a loaʻa paha ʻoe i kahi anemia (ʻaʻole lawa nā koko koko ʻulaʻula i loko o ke koko e halihali i ka oxygen i ke koena o ke kino), ka maʻi pale maʻi kanaka (HIV), loaʻa i ka pale maʻi Syndrome (AIDS), nā ʻano ʻē aʻe e hoʻopili i kāu ʻōnaehana pale, a i ʻole hepatitis B (kahi maʻi viral e hōʻino ai i ke ake) a i ʻole kekahi ʻano o nā maʻi ate ʻē aʻe ma mua o ka hepatitis C.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka boceprevir.
• e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hiki paha ke hāpai. Inā he kāne ʻoe, e haʻi i kāu kauka inā hāpai kāu hoa, hoʻolālā e hāpai, a i ʻole hiki paha i hāpai. Pono e kiʻi ʻia ʻo Boceprevir me ribavirin i hiki ke hōʻeha nui i ka fetus. Pono ʻoe e hoʻohana i ʻelua mau hana o ka kaohi hānau ʻana e pale ai i ka hāpai ʻana i loko ou a i ʻole kāu pakanā i kou wā e mālama ʻia ai me kēia mau lāʻau a no 6 mau mahina ma hope o kāu lapaʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana āu e hoʻohana ai; hormonal contraceptives (pills kaohi hānau, pāʻina, implants, apo, a i ʻole nā ​​injection) ʻaʻole holo pono paha i nā wahine e lawe nei i kēia mau lāʻau. Pono ʻoe a me kāu pakanā e hoʻāʻo no ka hāpai keiki i kēlā me kēia mahina i kāu mālama ʻana a no 6 mau mahina ma hope o kāu lapaʻau. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i kēia mau lāʻau, e kelepona koke i kāu kauka.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala me ka ʻai ke hoʻomanaʻo ʻoe iā ia. Eia nō naʻe, inā he 2 mau hola a ʻoi iki paha ma mua o ka manawa i hoʻonohonoho ʻia no kāu kaukana aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Boceprevir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• hoʻololi i ka hiki ke ʻono
• nalo ʻai ʻole
• luhi nui loa
• paʻakikī e hiamoe a hiamoe paha
• ukiuki
• poho lauoho
• ʻili maloʻo
• hūwī

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pokole o ka hanu
• ʻūpā
• maule ana
• nāwaliwali
• ʻeha ka ʻāʻī, ke kuni, ke anu, a me nā ʻōuli ʻē aʻe o ka maʻi

Hoʻokumu paha ʻo Boceprevir i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. Hiki iā ʻoe ke mālama i nā capsule i ka mahana wela a mamao aku mai ka wela a me ka makū (ʻaʻole i loko o ka lua) no ʻekolu mau mahina. Hiki iā ʻoe ke mālama i nā capsule i loko o ka pahu hau a hiki i ka lā palena pau i paʻi ʻia ma ka lepili i hala. E hoʻolei i nā lāʻau i hala i ka wā kahiko a pono ʻole paha. E kamaʻilio me kāu kauka lāʻau e pili ana i ka hoʻolei kūpono ʻana o kāu lāʻau.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā boceprevir.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Victrelis^®