ʻO Romidepsin Injection

Anter

• Ma mua o ka loaʻa ʻana o ka injection romidepsin,
• Hoʻokomo paha ʻo Romidepsin injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

Hoʻohana ʻia ʻo Romidepsin injection e mālama i ka limahana limahana T-cell (CTCL; kahi hui o nā maʻi ʻino o ka ʻōnaehana pale i ʻike mua ʻia e like me nā huehue o ka ʻili) i ka poʻe i mālama mua ʻia me hoʻokahi lāʻau ʻē aʻe. Hoʻohana pū ʻia ʻo Romidepsin injection e mālama i ka lymphoma T-cell peripheral (PTCL; kahi ʻano o ka lymphoma non-Hodgkin) i ka poʻe i mālama mua ʻia me hoʻokahi lāʻau ʻē aʻe. Aia ʻo Romidepsin injection i loko o ka papa o nā lāʻau i kapa ʻia nā mea hoʻohālua histone deacetylase (HDAC). Hana ia ma ka hoʻolohi ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Romidepsin injection me he pauma e hoʻopili ʻia me ka wai e hoʻokomo ʻia i loko o ke aniani (i loko o ke aa) ma kahi o 4 mau hola e ke kauka a kahu maʻi paha. Hāʻawi pinepine ʻia ia i nā lā 1, 8, a me 15 o kahi pōʻaiapuni 28 mau lā. Hiki ke hana hou i kēia pōʻaiapau ke hoʻomau ka hana ʻana o ka lāʻau lapaʻau a ʻaʻole kumu ʻia nā hopena ʻino.

E kamaʻilio me kāu kauka e pili ana i nā hopena āpau āu e ʻike ai i kāu wā e mālama ai me ka injection romidepsin. Inā loaʻa iā ʻoe kekahi mau hopena ʻehaʻeha, hiki i kāu kauka ke hōʻoki i kāu hoʻomaʻamaʻa mau ʻana a i kekahi manawa paha a / a i ʻole hoʻemi i kāu lāʻau.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection romidepsin,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka inikua romidepsin, kekahi lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka inikua romidepsin. E noi i kāu kauka lāʻau a nānā i ka ʻike hoʻomanawanui no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E ʻōlelo pono i kekahi o kēia mau mea: kekahi antibiotic e like me clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Erythrocin), moxifloxacin (Avelox), a me telithromycin (Ketek); nā anticoagulants (nā mea lahilahi o ke koko) e like me warfarin (Coumadin, Jantoven); nā antifungals e like me itraconazole (Sporanox), ketoconazole (Nizoral), a me voriconazole (Vfend); cisapride (Propulsid) (ʻaʻole loaʻa ma ka U.S.); dexamethasone; nā lāʻau no ka maʻi pale maʻi (HIV) e like me atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (i Kaletra, Norvir), a me saquinavir (Invirase); nā lāʻau no ke kuʻi puʻuwai ʻole e like me amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl), quinidine (Quinidex), a me sotalol (Betapace, Betapace AF); kekahi mau lāʻau no ka hopu ʻana e like me ka carbamazepine (Epitol, Equetro, Tegretol), phenobarbital, a me phenytoin (Dilantin); nefazodone; pimozide (Orap); rifabutin (Mycobutin); rifampin (Rifadin, ma Rifamate, ma Rifater, Rimactane); rifapentine (Priftin); sparfloxacin (Zagam); aiʻole thioridazine (Mellaril). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka inikua romidepsin, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi aku i kāu kauka inā he pākī kou, ka luaʻi, a i ʻole ka diarrhea ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau me ka inikua romidepsin. E haʻi aku i kāu kauka inā loaʻa a i ʻole loaʻa paha iā ʻoe kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hiki ai ke hōʻeha i ka puʻuwai ʻole, maʻule, a make koke paha), kahi puʻuwai puʻuwai ʻole a wikiwiki paha, ʻoi aku ka liʻiliʻi o ka potassium a me ka magnesium i loko o kou koko , hepatitis B (HBV; kahi maʻi i hoʻopili ʻia i ke akepaʻa a hiki ke hōʻeha ʻia i ke ake ake a i ʻole ke kanesa maʻi akepau), Epstein Barr virus (EBV; he virus herpes nāna e hoʻokumu i ka mononucleosis infectious a pili pū ʻia me kekahi mau maʻi maʻi maʻi), a i ʻole ke ake, nā puʻupaʻa, a i ʻole maʻi maʻi puʻuwai.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. E nānā paha kāu kauka inā he hāpai ʻoe ma mua o kou hoʻomaka ʻana i kāu lāʻau. Pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu mālama ʻana me ka injection romidepsin a no hoʻokahi mahina ma hope o kāu hopena hope loa. Eia nō naʻe, ʻaʻole pono ʻoe e hoʻohana i nā mea pale hormonal (estrogen) (nā lāʻau kaohi hānau, nā pāhoʻi, nā apo, nā implant, a i ʻole nā ​​injection) no ka mea hiki i ka romidepsin injection ke hoʻopau i kēia mau lāʻau mai ka hana e like me ka mea e pono ai. Inā he kāne ʻoe me kāu hoa wahine i hiki ke hāpai, e ʻike pono e hoʻohana i ka kaohi hānau i kāu wā e mālama ai me ka injection romidepsin a no hoʻokahi mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana. Inā hāpai ʻoe i ka loaʻa ʻana o ka inikua romidepsin, e kāhea i kāu kauka. Hiki i ka Romidepsin injection ke hōʻeha i ka fetus. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana me ka injection romidepsin a no ka liʻiliʻi he 1 pule ma hope o kāu hopena hope loa.
• inā ke ʻoki ʻia ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e loaʻa ana iā ʻoe kahi injection romidepsin.

E hōʻoia e inu i ka nui o nā wai no 3 mau lā ma hope o kēlā me kēia maʻamau o ka inikua romidepsin.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻulu a me ka inu ʻana i ka wai momona a loaʻa ka lāʻau.

Hoʻokomo paha ʻo Romidepsin injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• kōpaʻa
• ʻeha ka ʻōpū
• ʻeha nā waha
• ʻeha poʻo
• ua loli ke ʻano o ka ʻono
• nalo ʻai ʻole
• ʻūlili

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• nāwaliwali a nāwaliwali paha
• ʻili mae
• pokole o ka hanu
• ʻeha ka umauma
• kuʻi puʻuwai ʻole
• luʻuluʻu a maule paha
• paopao maʻalahi a hoʻokahe koko paha
• fiva, batukū, maʻi palū e like me nā ʻōuli, ʻeha nā mākala, puhi i ka urination, nā pilikia ʻili o ka ʻili, a me nā ʻōuli ʻē aʻe o ka maʻi (hiki i 30 mau lā ma hope o kāu lapaʻau
• hūwī
• ʻili a ʻiliʻili paha
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo

Hoʻokomo paha ʻo Romidepsin injection i nā pilikia momona. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana o kēia lāʻau inā makemake ʻoe e loaʻa he keiki.

Hoʻokomo paha ʻo Romidepsin injection i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka inikua romidepsin.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka injection romidepsin.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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