Mea Kākau: Clyde Lopez
Lā O Ka Hana: 24 Iulai 2021
HōʻAno Hou I Ka Lā: 1 Apelila 2025
Anonim
How does Niacin (B3) Work? (+ Pharmacology)
Wikiō: How does Niacin (B3) Work? (+ Pharmacology)

Anter

ʻO Niacin kekahi ʻano o ka wikamina B3. ʻIke ʻia i nā meaʻai e like me ka hū, kaʻiʻo, ka iʻa, ka waiū, nā hua manu, nā mea kanu ʻōmaʻomaʻo, a me nā hua cereal. Hana ʻia ʻo Niacin i loko o ke kino mai ka tryptophan, i loaʻa i loko o nā meaʻai protein. Ke lawe ʻia ma ke ʻano he pākuʻi, ʻike pinepine ʻia ka niacin me ka hui pū me nā huaora B ʻē aʻe.

Mai hoʻohuikau i ka niacin me NADH, niacinamide, inositol nicotinate, IP-6, a i ʻole tryptophan. E ʻike i nā papa inoa ʻokoʻa no kēia mau kumuhana.

Ua ʻae ʻia nā palapala kuhikuhi o ka niacin e ka US Food and Drug Administration (FDA) no ke kolesterol kiʻekiʻe a e hoʻonui i nā pae o kahi ʻano kikoʻī o ke kolako maikaʻi, i ʻike ʻia ʻo HDL. Lawe ʻia nā mea hoʻopihapiha Niacin a me nā huahana kuhikuhi e ka waha no ka pale ʻana i ka lawa ʻole o ka wikamina B3 a me nā ʻano pili e like me pellagra.

Nā Laʻau Laʻau Kūlohelohe Kūlohelohe nā helu kūpono e pili ana i nā hōʻike ʻepekema e like me ka pālākiō e hiki mai ana: Ka maikaʻi, ka hopena maikaʻi, ka hopena maikaʻi, ka hopena maikaʻi ʻole, ka maikaʻi ʻole, ka maikaʻi ʻole, a me ka lawa ʻole o nā hōʻike i ka helu.

Nā helu kūpono no NIACIN penei:


Pili paha ia no ...

  • Nā pae maʻamau o ke kōkō a me nā momona o ke koko (dislipidemia). Ua ʻae ʻia kekahi mau huahana niacin e ka U.S. Food and Drug Administration (FDA) ma ke ʻano he huahana kuhikuhi no ka mālama ʻana i nā kiʻekiʻe o nā momona o ke koko. Hele pinepine kēia mau huahana niacin i ka ikaika ma mua o 500 mg a ʻoi paha. ʻO nā ʻano hana hoʻopihapiha hoʻopihapiha o ka niacin e hele pinepine mai i nā ikaika o 250 mg a ʻoi iki paha. Ma muli o ke koi ʻia ʻana o nā koina kiʻekiʻe loa o ka niacin no ka hoʻomaikaʻi ʻana i nā kiʻekiʻe kolesterol, ʻaʻole kūpono ka mea kōkua dietary niacin. Hiki ke hoʻohui ʻia ʻo Niacin me nā lāʻau hoʻoliʻiliʻi kolesterol i ka lawa ʻole o ka papaʻai a me ka lāʻau hoʻokahi. Hoʻomaikaʻi ʻo Niacin i nā pae kolesterol, akā ʻaʻole hoʻomaikaʻi i nā hopena o ka maʻi maʻi e like me ka puʻuwai puʻuwai a me nā hahau.
  • ʻO kahi maʻi i hoʻokumu ʻia e ka niacin deficit (pellagra). Ua ʻae ʻia ʻo Niacin e ka U.S. Food and Drug Administration (FDA) no kēia hoʻohana. Eia nō naʻe, hiki i ka niacin ke kumu i ka "flushing" (ʻulaʻula, aniani, a me ke kani.) No laila kekahi huahana, i kapa ʻia he niacinamide, makemake ʻia i kekahi manawa no ka mea ʻaʻole ia ka hopena o kēia ʻaoʻao.

E kūpono paha no ...

  • Nā pae kūpono ʻole o nā momona o ke koko i ka poʻe me ka maʻi HIV / AIDS. ʻO ka lawe ʻana i ka niacin me he mea lā e hoʻomaikaʻi ai i nā pae o ka kolesterol a me nā momona o ke koko i kapa ʻia ʻo triglycerides i nā mea maʻi me kēia ʻano.
  • ʻO kahi hui o nā hōʻailona e hoʻonui i ka makaʻi o ka maʻi kō, ka maʻi puʻuwai, a me ka hahau (metabolic syndrome). ʻO ka lawe ʻana i ka niacin me he mea lā e hoʻonui i nā pae o lipoprotein kiʻekiʻe (HDL a i ʻole "maikaʻi") kolesterol a hoʻoliʻiliʻi i nā pae o nā momona o ke koko i kapa ʻia ʻo triglycerides i ka poʻe me ka maʻi metabolic. ʻO ka lawe ʻana i ka niacin me kahi omega-3 fatty acid i kuhikuhi ʻia e ʻoi aku ka maikaʻi.

Maikaʻi ʻole no ...

  • Maʻi maʻi puʻuwai. Hōʻike ka noiʻi kiʻekiʻe loa ʻaʻole pale ka niacin i ka hōʻeha puʻuwai a i ʻole ka hahau ʻana i ka poʻe i lawe i ka niacin e pale a mālama paha i nā maʻi puʻuwai. ʻAʻole hōʻike ʻia ʻo Niacin e hōʻemi i ka makaʻu o ka make. ʻAʻole pono e lawe ʻia ʻo Niacin e mālama a pale aku i nā maʻi puʻuwai.

ʻAʻole lawa nā hōʻike e hōʻike i ka pono no ...

  • ʻO ka paʻakikī o nā aʻa (atherosclerosis). Lawe ka niacin e ka waha me nā lāʻau i kapa ʻia ʻo ka bile acid sequestrants e hōʻemi ai i ka paʻakikī o nā aʻa i nā kāne me kēia ʻano. Me he mea lā ʻoi aku ka maikaʻi o ka hana ma nā kāne me nā kiʻekiʻe o nā momona o ke koko i kapa ʻia ʻo triglycerides. Akā ʻo ka lawe ʻana i ka niacin ʻaʻole ia e hoʻemi i ka paʻakikī o nā aʻa i nā mea maʻi me kahi maʻi i kapa ʻia ʻo ka maʻi ākea peripheral (PAD). Eia kekahi, ʻaʻole pale ʻo niacin i nā hanana cardiovascular e like me ka puʻuwai a i ʻole ka hahau.
  • Maʻi Alzheimer. ʻO ka poʻe e ʻai i nā niacin ʻoi aku ka nui mai ka meaʻai a me nā multivitamin e like me ka haʻahaʻa o ka loaʻa ʻana o ka maʻi Alzheimer ma mua o ka poʻe e ʻai liʻiliʻi ana i ka niacin. Akā ʻaʻohe mea hōʻike e kōkua ana i ka lawe ʻana i ka pāʻina niacin e pale aku ai i ka maʻi ʻo Alzheimer.
  • Kālepaʻa. ʻO ka poʻe e ʻai i ka papaʻai kiʻekiʻe ma ka niacin hiki ke hoʻemi ʻia ka manawa kūpono e hoʻomohala i nā cataract nuklear. ʻO ka cataract nuklear ka ʻano cataract maʻamau. ʻAʻole ʻike ʻia ka hopena o ka lawe ʻana i ka pāʻina niacin.
  • An maʻiʻaʻai o na naʻau i ke kumu diarrhea (cholera). ʻO ka lawe ʻana i ka niacin e ka waha me he mea lā e hōʻemi ana i ka maʻi diarrhea i ka poʻe me ke kolera.
  • ʻO ka hana Erectile (ED). ʻO ka lawe ʻana i ka niacin hoʻolōʻihi ʻia i ka manawa hiamoe no 12 mau pule e like me ke kōkua ʻana i nā kāne i loaʻa iā ED a me nā kiʻekiʻe lipid kiʻekiʻe e mālama i kahi kūkulu i ka wā o ka moekolohe.
  • Nā pae kiʻekiʻe o ka phosphate i ke koko (hyperphosphatemia). ʻO ka poʻe me ke kīnā ʻole o ka puʻupaʻa e loaʻa i nā pae koko kiʻekiʻe o phosphate. Hōʻike kekahi o nā noiʻi mua i ka lawe ʻana i ka niacin hiki ke hoʻemi i ke kiʻekiʻe o ke koko o ka phosphate i ka poʻe me nā maʻi puʻuwai pae hope loa a me nā pae kiʻekiʻe o ka phosphate koko. Akā hōʻike ʻia kahi noiʻi ʻē aʻe i ka lawe ʻana i ka niacin ʻaʻole e hoʻohaʻahaʻa i nā pae o ka phosphate koko i ka poʻe e lawe pū nei i nā lāʻau i hoʻohana ʻia e hoʻohaʻahaʻa i nā pae o ka phosphate.
  • Ka pale o ke aa i ka maka (retinal vein occlusion): Hōʻike ka noiʻi mua i ka lawe ʻana i ka niacin i mea e hoʻomaikaʻi ai i ka maka i ka poʻe me kēia ʻano.
  • Maʻi maʻi maʻi maʻi: Ke hōʻike nei nā noiʻi mua i ka lawe ʻana i ka niacin ʻaʻole ia e hoʻomaikaʻi i nā pae o nā momona o ke koko i ka poʻe me nā maʻi maʻi sickle.
  • Huehue.
  • Hoʻohana maʻi ʻalekohola.
  • Hana Athletic.
  • Ka maʻi deficit-hyperactivity maʻi (ADHD).
  • Kaumaha.
  • Puʻupuʻu.
  • Nā hoʻoliʻiliʻi hoʻowalewale ʻia e ka lāʻau.
  • ʻO Migraine.
  • Maʻi maʻi.
  • Schizophrenia.
  • Nā kūlana ʻē aʻe.
Pono hou nā hōʻike e hōʻike i ka niacin no kēia mau hoʻohana.

Hoʻokomo ʻia ʻo Niacin e ke kino ke hoʻoheheʻe ʻia i ka wai a lawe ʻia e ka waha. Hoʻohuli ʻia i niacinamide inā lawe ʻia i nā nui i ʻoi aku i ka mea e pono ai ke kino.

Koi ʻia ʻo Niacin no ka hana kūpono o nā momona a me nā kō i ke kino a mālama i nā hunaola olakino. Ma nā koina kiʻekiʻe, hiki i ka niacin ke kōkua i ka poʻe me ka maʻi puʻuwai ma muli o nā hopena maikaʻi i ka hoʻopili ʻana. Hiki iā ia ke hoʻomaikaʻi i nā pae o kekahi ʻano momona i kapa ʻia nā triglycerides i loko o ke koko.

Hiki i ka hemahema Niacin ke kumu i kahi ʻano i kapa ʻia ʻo pellagra, ka mea e hoʻonāukiuki ai i ka ʻili, a me ka diarrhea, a me ka dementia. ʻO Pellagra ka mea maʻamau i ke kenekulia iwakālua, akā ʻoi aku ka liʻiliʻi i kēia manawa, ʻoiai ua paʻa paʻa kekahi mau meaʻai i ka palaoa me ka niacin. Ua hoʻopau loa ʻia ʻo Pellagra i ka moʻomeheu komohana.

ʻO ka poʻe me kaʻai maikaʻi ʻole, ka wai ʻona, a me kekahi o nā tumors e ulu lohi ana i kapa ʻia ʻo nā tumo carcinoid e makaʻu paha no ka hemahema niacin. Ke lawe ʻia e ka waha: Niacin ʻo ia LIKELY SAFE no ka hapanui o ka poʻe ke lawe kūpono ʻia. Palekana nā huahana i kuhikuhi ʻia me ka niacin ke lawe ʻia e like me ke kuhikuhi. Palekana ʻo Niacin i nā meaʻai a i ʻole niacin mea hoʻopihapiha ke lawe ʻia i nā kaha ma lalo o 35 mcg i kēlā me kēia lā.

ʻO kahi hopena ʻaoʻao maʻamau o ka niacin kahi hopena pāheʻe. ʻO kēia ke kumu o ka puhi ʻana, ka ʻūlū ʻana, ka ʻili ʻana, a me ka ʻulaʻula o ka maka, nā lima, a me ka umauma, a me nā poʻo hina. Ke hoʻomaka nei me nā lāʻau liʻiliʻi o ka niacin a me ka lawe ʻana i 325 mg o ka aspirin ma mua o kēlā me kēia mahele o ka niacin e kōkua i ka hōʻemi ʻana i ka hopena o ka wai. ʻO ka maʻamau, hele kēia hopena ma ke ʻano maʻa o ke kino i ka lāʻau. Hiki i ka waiʻona ke hana i ka hopena flushing i mea ʻoi aku ka maikaʻi. Hōʻalo i ka nui o ka waiʻona i ka wā e lawe ana i ka niacin.

ʻO nā hopena ʻē aʻe ʻē aʻe o ka niacin ka huhū o ka ʻōpū, ka ʻōpū o ka ʻōpū, ka poni ʻana, ka ʻeha o ka waha, a me nā pilikia ʻē aʻe.

Ke lawe ʻia nā lāʻau i ʻoi aku ma mua o 3 gram i kēlā me kēia lā o ka niacin, hiki i nā hopena ʻē aʻe koʻikoʻi ke kū. Hoʻopili kēia i nā pilikia o ke ake, gout, ulcer o ka digestive tract, nalowale o ka hihiʻo, ke kō kiʻekiʻe o ke kō, ke kuʻi puʻuwai ʻole, a me nā pilikia koʻikoʻi ʻē aʻe.

Nā mālama a me nā ʻōlelo aʻoaʻo kūikawā:

Hāpai a me ka hānai umauma: Niacin ʻo ia LIKELY SAFE no nā wahine hāpai a hānai hānai ke lawe ʻia e ka waha i nā nui i ʻōlelo ʻia. ʻO ka nui o ka niacin i koi ʻia no nā wahine hāpai a hānai hānai paha ʻo 30 mg i kēlā me kēia lā no nā wahine ma lalo o 18 mau makahiki, a 35 mg no nā wahine ma mua o 18.

Nā keiki: Niacin ʻo ia LIKELY SAFE ke lawe ʻia e ka waha i nā helu i paipai ʻia no kēlā me kēia pae makahiki. Akā pono nā keiki e hōʻalo i ka lawe ʻana i nā kaha o ka niacin ma luna o nā palena o kēlā me kēia lā, ʻo 10 mg no nā keiki 1-3 mau makahiki, 15 mg no nā keiki 4-8 mau makahiki, 20 mg no nā keiki 9-13 mau makahiki, a 30 mg no nā keiki 14-18 mau makahiki.

Nā Pāhoihoi: E hoʻomāhuahua paha ʻo Niacin i nā maʻi āpau ma o ka hoʻoulu ʻana i ka histamine, ke kemikino e pili ana i nā ʻōnaehana maʻi, e hoʻokuʻu ʻia.

ʻO ka maʻi puʻuwai / angina paʻa ʻole: Hiki i ka nui o ka niacin ke hoʻonui i ka makaʻu o ka naʻau kaulike ʻole. E hoʻohana me ka akahele.

Maʻi Crohn: Loaʻa i nā kānaka me ka maʻi Crohn i nā pae niacin haʻahaʻa a koi i ka supplementation i ka wā o flare-ups.

Diabetes: Hoʻonui paha ʻo Niacin i ke kō kō. ʻO ka poʻe me ka maʻi diabetes e lawe i ka niacin pono e nānā pono i kā lākou kō kō.

Maʻi maʻi gallbladder: Hana ʻo Niacin i mea e ʻoi aku ai ka maʻi maʻi

Goute: Nui ka nui o ka niacin i lawe mai i ka gout.

ʻO ka maʻi kīwī: E hōʻiliʻili paha ʻo Niacin i ka poʻe me nā maʻi puʻupaʻa. Hiki paha i kēia ke hōʻino.

Maʻi maʻi ate: Hoʻonui paha ʻo Niacin i ka hōʻino o ke ake. Mai hoʻohana i nā nui inā loaʻa ka maʻi ate.

ʻŌpū ʻōpū a ʻōpū paha: E hoʻonui ʻo Niacin i ka ulcer. Mai hoʻohana i nā nui inā loaʻa ʻoe nā maʻi maʻi maʻi.

Ke kaomi haʻahaʻa haʻahaʻa loa: E hoʻohaʻahaʻa paha ʻo Niacin i ke kahe o ke koko a hoʻonui i kēia ʻano.

ʻOki kino: E hoʻopilikia paha ʻo Niacin i ke kaohi kō kō i ka wā a ma hope o ke kaha ʻana. E hoʻōki i ka lawe ʻana i ka niacin ma kahi o 2 mau pule ma mua o ka hōʻoki ʻia ʻana.

ʻO nā waihona momona e pili ana i nā tendons (tendon xanthomas): Hiki i ka Niacin ke hoʻonui i ka hopena o nā maʻi ma xanthomas.

Nā maʻi thyroid: ʻO ka thyroxine kahi hormone i hana ʻia e ka thyroid gland. Hiki i ka Niacin ke hoʻohaʻahaʻa i nā pae o ke koko o thyroxine. Hoʻonui paha kēia i nā ʻōuli o kekahi mau maʻi thyroid.

Kānāwai
E akahele me kēia hui ʻana.
ʻAlekohola (Ethanol)
Hiki iā Niacin ke hana i ka flush a me ka ʻili. ʻO ka inu ʻana i ka waiʻona me ka niacin e ʻoi aku ai ka maikaʻi o ka holoi ʻana a me ka ʻili. Aia kekahi hopohopo paha ʻo ka ʻai ʻana i ka waiʻona me ka niacin e hoʻonui ai i ka manawa o ka hōʻino ʻia o ke ake.
Allopurinol (Zyloprim)
Hoʻohana ʻia ʻo Allopurinol (Zyloprim) e mālama ai i ka gout. ʻO ka lawe ʻana i nā kaha nui o ka niacin e hoʻomāhuahua ai i ka gout a hoʻēmi i ka maikaʻi o ka allopurinol (Zyloprim).
ʻO Clonidine (Catapres)
ʻO Clonidine a me niacin ka haʻahaʻa haʻahaʻa haʻahaʻa. Lawe i ka niacin me ka clonidine paha e hoʻohaʻahaʻa i kou kahe koko.
Gemfibrozil (Lopid)
Lawe i ka niacin me gemfibrozil paha e hōʻino i nā mākala i kekahi poʻe. E hoʻohana me ka akahele.
Nā lāʻau no ka maʻi kō (Antidiabetes lāʻau)
Hoʻohana i nā koina kiʻekiʻe o ka niacin (ma kahi o 3-4 gram i kēlā me kēia lā) e hoʻonui i ke kō kō. Ma ka hoʻonui ʻana i ke kō kō, hiki i ka niacin ke hoʻemi i ka hopena o nā lāʻau diabetes. E nānā pono i kāu kō kō. Pono e hoʻololi i ka mahele lāʻau o kāu lāʻau diabetes.

ʻO kekahi mau lāʻau i hoʻohana ʻia no ka maʻi kō me glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), metformin (Glucophage), nateglinide (Starlix), repaglinide (Prandin), chlorpropamide ( Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), a me nā mea ʻē aʻe.
Nā lāʻau no ke koko kiʻekiʻe (Antihypertensive lāʻau lapaʻau)
Ke hoʻohana nei i ka niacin me nā lāʻau e hoʻohaʻahaʻa i ke kahe o ke koko e hoʻonui i nā hopena o kēia mau lāʻau a hoʻoliʻiliʻi paha i ke kahe o ke koko.

ʻO kekahi mau lāʻau no ke koko kiʻekiʻe me captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), a me nā mea ʻē aʻe he nui. .
Nā lāʻau i hiki ke hōʻeha i ke ake (Hepatotoxic drug)
Hiki iā Niacin ke hōʻeha i ke ake. ʻO nā hoʻomākaukau niacin hoʻomau-hoʻokuʻu ke ʻano ʻoi aku ka nui o ka makaʻu. Lawe i ka niacin me nā lāʻau e hōʻino paha i ke akepaʻa ke hoʻonui i ka makaʻu o ka hōʻino ʻana o ke ake. Mai lawe i ka niacin inā lawe ʻoe i kahi lāʻau e hiki ai ke hōʻeha i ke ake.

ʻO kekahi mau lāʻau e hiki ai ke hōʻeha i ke akepaʻa me ka acetaminophen (Tylenol a me nā mea ʻē aʻe), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporanozole (Sporlucan), itraconazole (Sporanozole (Spiflucan), itraconazole (Spor)) erythromycin (Erythrocin, Ilosone, kekahi), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), a me nā mea ʻē aʻe he nui.
Nā lāʻau i hoʻolohi i ke kō ʻana o ke koko (Anticoagulant / Antiplatelet drug)
Niacin paha e hoʻolohi i ke kō ʻana o ke koko. Lawe i ka niacin me nā lāʻau lapaʻau e hōʻemi ana i ka ʻōpala ʻana e hoʻonui ai i ka manawa o ka palapū a me ke kahe ʻana o ke kahe.

ʻO kekahi mau lāʻau e lohi ai ke kāpili ʻana o ke koko me aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), a me nā mea ʻē aʻe.
Nā lāʻau i hoʻohana ʻia no ka hoʻohaʻahaʻa ʻana i ka kolesterol (Bile acid sequestrants)
ʻO kekahi mau lāʻau no ka hoʻohaʻahaʻa ʻana i ke kōkōkō i kapa ʻia he best acid sequestrants hiki ke hōʻemi i ka nui o ka niacin e ʻimi ai ke kino. Hoʻoemi paha kēia i ka maikaʻi o ka niacin. Lawe i ka niacin a me nā lāʻau i 4-6 mau hola ke kaʻawale.

ʻO kekahi o kēia mau lāʻau i hoʻohana ʻia no ka hoʻohaʻahaʻa ʻana i ka kolesterol e komo pū me cholestyramine (Questran) a me colestipol (Colestid).
Nā lāʻau i hoʻohana ʻia no ka hoʻohaʻahaʻa ʻana i ka cholesterol (Statins)
Hiki i ka Niacin ke hoʻopili maikaʻi i nā mākala. ʻO kekahi mau lāʻau i hoʻohana ʻia no ka hoʻohaʻahaʻa ʻana i ka cholesterol i kapa ʻia he statins hiki ke hoʻopili i nā mākala. ʻO ka lawe ʻana i ka niacin me kēia mau lāʻau e hoʻonui ai i ka pilikia o nā pilikia i nā mākala.

ʻO kekahi o kēia mau lāʻau i hoʻohana ʻia no ka kolesterol kiʻekiʻe me rosuvastatin (Crestor), atorvastatin (Lipitor), lovastatin (Mevacor), pravastatin (Pravachol), fluvastatin (Lescol), a me simvastatin (Zocor).
Probenecid (Benemid)
Hoʻohana ʻia ʻo Probenecid e mālama i ka gout. ʻO ka lawe ʻana i nā kaha nui o ka niacin e hoʻomāhuahua paha i ka gout a hoʻemi i ka hopena o ka probenecid.
Sulfinpyrazone (Anturane)
Hoʻohana ʻia ʻo Sulfinpyrazone (Anturane) e mālama ai i ka gout. ʻO ka lawe ʻana i nā kaha nui o ka niacin e hoʻomāhuahua paha i ka gout a hoʻoliʻiliʻi i ka pono o sulfinpyrazone (Anturane).
Hīmona thyroid
Hana maoli ke kino i nā hormone thyroid. Hiki i ka Niacin ke hoʻēmi i nā pae hormonone thyroid. ʻO ka lawe ʻana i ka niacin me nā huaale hormonone thyroid e hoʻoliʻiliʻi paha i nā hopena a me nā hopena ʻaoʻao o ka hormone thyroid.
Mea liʻiliʻi
E makaʻala me kēia hui pū.
ʻAspirin
Hoʻohana pinepine ʻia ʻo Aspirin me ka niacin e hoʻoliʻiliʻi i ka pāheʻe ʻia ʻana e ka niacin. ʻO ka lawe ʻana i nā kaha kiʻekiʻe o ka aspirin e hoʻoliʻiliʻi paha i ka wikiwiki o ka hoʻopau ʻana o ke kino i ka niacin. Hiki i kēia ke kumu he nui nā niacin i loko o ke kino a alakaʻi paha i nā hopena ʻaoʻao. Eia nō naʻe, ʻaʻole like ka pilikia o nā kaha haʻahaʻa o ka aspirin i hoʻohana pinepine ʻia no ka pāheʻe ʻana e pili ana i ka niacin.
Pākuʻi Nicotine (Nicoderm)
Hiki i ka Niacin ke hana i ka flush a me ka dizziness i kekahi manawa. Hiki i ka patch nicotine ke hoʻoulu a me ka puʻupuʻu. Lawe i ka niacin a i ʻole niacinamide a hoʻohana i kahi patch nicotine hiki ke hoʻonui i ka hiki ke lilo i ka pulu a me ka palaho.
Beta-carotene
Hoʻohui ʻia kahi hui o ka niacin a me ka simvastatin (Zocor) lāʻau hoʻōla i HDL (lipoprotein kiʻekiʻe) kolesterol ("kolesterol maikaʻi") i ka poʻe me ka maʻi puʻuwau coronary a me nā pae HDL haʻahaʻa. Eia nō naʻe, ke lawe nei i ka niacin me nā hui pū o nā antioxidant, me beta-carotene, me he mea lā e hōʻemi i kēia piʻi ʻana i HDL. ʻAʻole maopopo inā pili kēia hopena i ka poʻe ʻaʻohe o lākou maʻi puʻuwai coronary.
ʻO Chromium
Lawe pū ka niacin a me ka chromium i lalo i ke kō kō. Inā loaʻa ʻoe i ka maʻi diabetes a lawe pū i nā mea hoʻohui chromium a me niacin pū, e kiaʻi i kāu kō kō i ʻole e hoʻohaʻahaʻa.
ʻO nā lau nahele a me nā mea hoʻopili e hōʻino paha i ke ake
ʻO Niacin, keu hoʻi i nā koina kiʻekiʻe hiki ke hōʻeha i ke ake. Lawe i ka niacin me nā mea kanu ʻē aʻe a i ʻole nā ​​mea hoʻopili e hōʻino ai i ke ake ke hoʻonui i kēia pilikia. ʻO kekahi o kēia huahana me androstenedione, lau borage, chaparral, comfrey, dehydroepiandrolone (DHEA), germander, kava, pennyroyal aila, ʻulaʻena hū, a me nā mea ʻē aʻe.
ʻO nā lau nahele a me nā mea hoʻopili e hoʻoliʻiliʻi i ke kahe o ke koko
Niacin paha e hoʻohaʻahaʻa i ke kahe o ke koko. Lawe i ka niacin me nā mea kanu a me nā mea hoʻohui ʻē aʻe e hoʻoliʻiliʻi hoʻi i ke kahe o ke koko. ʻO nā mea kanu a me nā mea hoʻopihapiha ʻē aʻe e hiki ke hoʻohaʻahaʻa i ke kahe o ke koko e like me andrographis, casein peptides, claw o ka pōpoki, coenzyme Q10, L-arginine, lycium, ʻupena stinging, theanine, a me nā mea ʻē aʻe.
ʻO nā lau nahele a me nā mea hoʻopili e lohi ai i ke kāpili ʻana o ke koko
Niacin e lohi paha i ke kāpili ʻana o ke koko. ʻO ka hoʻohana ʻana i ka niacin me nā mea kanu a me nā mea hoʻopili ʻē aʻe e lohi ai ke kāpili ʻana o ke koko e hoʻonui i ka makaʻu o ke kahe ʻana i kekahi poʻe. ʻO kekahi mau mea kanu ʻē aʻe o kēia ʻano me Angelica, clove, danshen, kālika, ginger, Panax ginseng, a me nā mea ʻē aʻe.
Kombucha kī
Aia kekahi hopohopo e hōʻemi paha ka kī kombucha i ke komo ʻana o niacin. Eia naʻe, pono e aʻo hou ʻia kēia.
Selenium
Hoʻohui ʻia kahi hui o ka niacin a me ka simvastatin lāʻau lapaʻau (Zocor) i ka HDL (lipoprotein kiʻekiʻe) kolesterol ("kolesterol maikaʻi") i nā kānaka me nā maʻi puʻuwau coronary a me nā pae HDL haʻahaʻa. Eia nō naʻe, ke lawe nei i ka niacin me nā hui pū o nā antioxidant, me ka selenium, me he mea lā e hōʻemi i kēia piʻi ʻana o HDL. ʻAʻole maopopo inā pili kēia hopena i ka poʻe ʻaʻohe o lākou maʻi puʻuwai coronary.
ʻO Tropophan
Hiki ke hoʻololi i kekahi tryptophan mai ka papaʻai i niacin i loko o ke kino. ʻO ka lawe ʻana i ka niacin a me ka tryptophan pū e hoʻonui ai i nā pae a me nā ʻaoʻao ʻē aʻe o ka niacin.
ʻO Wikamina C
Hoʻohui ʻia kahi hui o ka niacin a me ka simvastatin (Zocor) lāʻau hoʻōla i HDL (lipoprotein kiʻekiʻe) kolesterol ("kolesterol maikaʻi") i ka poʻe me ka maʻi puʻuwau coronary a me nā pae HDL haʻahaʻa. Eia nō naʻe, ke lawe nei i ka niacin me nā hui pū ʻana o nā antioxidant, me ka lāʻau C, me he mea lā e hōʻemi i kēia piʻi ʻana o HDL. ʻAʻole maopopo inā pili kēia hopena i ka poʻe ʻaʻohe o lākou maʻi puʻuwai coronary.
ʻO Wikamina E
Hoʻohui ʻia kahi hui o ka niacin a me ka simvastatin lāʻau lapaʻau (Zocor) i ka HDL (lipoprotein kiʻekiʻe) kolesterol ("kolesterol maikaʻi") i nā kānaka me nā maʻi puʻuwau coronary a me nā pae HDL haʻahaʻa. Eia nō naʻe, ke lawe nei i ka niacin me nā hui pū o nā antioxidant, e like me ka lāʻau E, me he mea lā e hōʻemi i kēia piʻi ʻana o HDL. ʻAʻole maopopo inā pili kēia hopena i ka poʻe ʻaʻohe o lākou maʻi puʻuwai coronary.
Kiniki
Hiki i ke kino ke hana i ka niacin. ʻO ka poʻe nele i ka meaʻai a loaʻa ka hemahema niacin, e like me nā mea ʻona mau, hana i nā niacin keu inā lawe lākou i ka zinc. Nui aʻe paha ka makaʻu o nā hopena ʻē aʻe i pili i ka niacin e like me ka flushing ʻana a me ka ʻū ʻana inā e lawe pū ʻia ka niacin a me ka zinc.
Mea inu wela
Hiki iā Niacin ke kumu i ka pīpī a me ka aniani. Hoʻonui ʻia paha kēia mau hopena inā lawe ʻia ka niacin me kahi mea inu wela.
Ua aʻo ʻia nā mahele aʻe i ka noiʻi ʻepekema:

NA MAKAHIKI

E ka waha:
  • Generala: Ke papa inoa nei kekahi huahana huahana hoʻopihapiha niacin ma ka lepili i nā mea like niacin (NE). 1 mg o ka niacin like ia me 1 mg NE. Ke helu ʻia ka niacin ma kahi lepili ʻo NE, hiki ke hoʻopili pū me nā ʻano niacin ʻē aʻe, e like me niacinamide, inositol nicotinate, a me tryptophan. ʻO nā ʻāpana papaʻai papaʻai i kēlā me kēia lā no ka niacin i nā mākua he 16 mg NE no nā kāne, 14 mg NE no nā wahine, 18 mg NE no nā wahine hāpai, a me 17 mg NE no nā wahine lactating.
  • No ke kōpaʻa kiʻekiʻe: Pili ka hopena o ka niacin. Hoʻohana ʻia nā hana o ka niacin ma lalo o 50 mg a ʻo ke kiʻekiʻe he 12 mau gram i kēlā me kēia lā. Eia nō naʻe, ʻo ka piʻi nui loa o ka HDL a me ka emi o nā triglycerides e hana ʻia ma 1200 a 1500 mg / lā. ʻO nā hopena nui loa a Niacin ma LDL ma 2000 a 3000 mg / lā. Hoʻohana pinepine ʻia ʻo Niacin me nā lāʻau ʻē aʻe no ka hoʻomaikaʻi ʻana i nā kiʻekiʻe kolesterol.
  • No ka pale ʻana a me ka mālama ʻana i ka hemahema o ka wikamina B3 a me nā ʻano pili e like me pellagra: 300-1000 mg i kēlā me kēia lā i nā mahele i hoʻokaʻawale ʻia.
  • No ka mālama ʻana i ka paʻakikī o nā aʻa: ʻO ke kiʻekiʻe o nā niacin i like me 12 mau lā i kēlā me kēia lā. Eia nō naʻe, ua hoʻohana ʻia kahi mahele lāʻau e pili ana i 1 a 4 mau gram o ka niacin i kēlā me kēia lā, hoʻokahi a i ʻole me nā statins a i ʻole nā ​​bile acid sequestrants (kahi lāʻau hoʻohaʻahaʻa kolesterol) a hiki i nā makahiki 6.2.
  • No ka hōʻemi ʻana i ka poho o ka wai i hopena ʻia e ka cholera toxin: 2 gram i kēlā me kēia lā i hoʻohana ʻia.
  • No nā pae momona o ke koko kūpono ʻole ma muli o ka mālama ʻana no HIV / AIDS: Aia i 2 gram i kēlā me kēia lā i hoʻohana ʻia.
  • No ka maʻi metabolic: Ua lawe ʻia ʻo 2 gram o ka niacin i kēlā me kēia lā no 16 mau pule. I kekahi mau hihia, ʻo ka niacin 2 mau lā i kēlā me kēia lā, hoʻokahi a i ʻole i kēia ana, lawe ʻia me 4 mau gram o ka omega-3 ethyl esters (Lovaza, GlaxoSmithKline pharmaceutics).
E IV:
  • No ka pale ʻana a me ka mālama ʻana i ka hemahema o ka wikamina B3 a me nā ʻano pili e like me pellagra: 60 mg o ka niacin i hoʻohana ʻia.
E PILI ANA:
  • No ka pale ʻana a me ka mālama ʻana i ka hemahema o ka wikamina B3 a me nā ʻano pili e like me pellagra: 60 mg o ka niacin i hoʻohana ʻia.
KEIKI

E ka waha:
  • Generala: ʻO nā ʻāpono ʻai papa kuhikuhi ʻia i kēlā me kēia lā (RDA) no ka niacin i nā keiki he 2 mg NE no nā pēpē 0-6 mahina o ka makahiki, 4 mg NE no nā keiki pēpē 7-12 mau makahiki, 6 mg NE no nā keiki 1-3 mau makahiki. 8 mg NE no nā keiki 4-8 mau makahiki, 12 mg NE no nā keiki 9-13 mau makahiki, 16 mg NE no nā keikikāne 14-18 mau makahiki, a 14 mg NE no nā kaikamahine 14-18 makahiki.
  • No ka pale ʻana a me ka mālama ʻana i ka hemahema o ka wikamina B3 a me nā ʻano pili e like me pellagra: 100-300 mg i kēlā me kēia lā o ka niacin, hāʻawi ʻia i nā mahele i hoʻokaʻawale ʻia.
3-Pyridinecarboxylic Acid, Acide Nicotinique, Acide Pyridine-Carboxylique-3, Anti-Blacktongue Factor, Antipellagra Factor, B Complex Wikamina, Complexe de Vitamines B, Facteur Anti-Pellagre, Niacina, Niacine, Nicosedine, Nicotinic Acid, Pellagra Preventing Factor, ʻO Vitamin B3, Vitamin PP, Vitamina B3, Vitamine B3, Vitamine PP.

E aʻo hou aʻe ai pehea i kākau ʻia ai kēia ʻatikala, e ʻoluʻolu e ʻike i ka Nā Laʻau Laʻau Kūlohelohe Kūlohelohe ʻano hana.


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