Ke kuʻi microbiota fecal

Kōkua ke kāpili microbiota fecal (FMT) e pani i kekahi o nā "bacteria" maikaʻi ʻole o kou kolona me nā "bacteria maikaʻi". Kōkua ke kaʻina hana e hoʻihoʻi i nā bacteria maikaʻi i pepehi ʻia a i kaupalena ʻia paha e ka hoʻohana ʻana i nā lāʻau ʻaloʻalo. ʻO ka hoʻihoʻi ʻana i kēia kaulike i ke kolona e maʻalahi ai ke kaua ʻana i ka maʻi.

Hoʻopili ʻo FMT i ka hōʻiliʻili ʻana i ka pahu mai kahi mea hāʻawi olakino. E noi ana kāu mea mālama ola iā ʻoe e hoʻomaopopo i kahi mea hāʻawi. Koho ka hapanui o ka poʻe i kekahi ʻohana a i ʻole hoa pili. ʻAʻole pono ka mea hāʻawi e hoʻohana i nā lāʻau ʻaloʻolika no 2 a 3 mau lā i hala. E nānā ʻia lākou no nā maʻi i ke koko a i ʻole ka pahu.

I ka manawa e hōʻiliʻili ʻia, hui ʻia ka pahu o ka mea hāʻawi me ka wai saline a kānana ʻia. Hoʻololi ʻia ka hui ʻana i loko o kāu wahi digestive (kolona) ma o kahi paipu e hele i loko o kahi kolone (kahi wīwī lahilahi me kahi pahu liʻiliʻi). Hiki ke hoʻolauna ʻia ka bacteria maikaʻi i loko o ke kino e ka paipu e hele i loko o ka ʻōpū ma o ka waha. ʻO kahi hana ʻē aʻe e ale i kahi capsule i loaʻa ka pahu hāʻawi hāʻawi maloʻo maloʻo.

ʻO ka ʻōpū nui ka helu nui o nā koʻohune. He mea nui kēia mau koʻohune i kou mau ʻōpū no kou olakino, a ulu i kahi kaulike.

Kāhea ʻia kekahi o kēia mau bacteria Difficile ʻo Clostridioides (C difficile). I nā kālā liʻiliʻi, ʻaʻole ia e hoʻokumu i nā pilikia.

• Eia nō naʻe, inā loaʻa i kekahi kanaka nā ʻāpana antibiotics hou a kiʻekiʻe paha no kahi maʻi i kahi ʻē aʻe i ke kino, hiki ke hoʻopau ʻia ka hapa nui o nā bacteria i loko o ka ʻōpū. Hoʻonui a hoʻokuʻu ka bacteria i kahi lāʻau make.
• ʻO ka hopena paha ka nui loa o ka C difficile.
• ʻO kēia toxin ke kumu o ka pehu ʻana o ka ʻōpū nui e lilo i pehu a hoʻāpā, e hana ana i ke kuni, ka maʻi diarrhea, a me ke kahe ʻana o ke kahe.

Hiki i kekahi mau antibiotic ʻē aʻe ke lawe i ka C difficile bacteria ma lalo o kaohi. Inā ʻaʻole holo pono kēia, hoʻohana ʻia ʻo FMT e pani i kekahi o nā C difficile me nā "bacteria" maikaʻi a hoʻihoʻi i ke kaulike.

Hoʻohana ʻia ʻo FMT e mālama ai i nā kūlana e like me:

• Maʻi maʻi huhū huhū
• Maʻi Crohn
• Konipōpō
• Ulcerative colitis

Hoʻomaʻo i nā kūlana ʻē aʻe ma mua o ka hoʻi hou ʻana C difficile manaʻo ʻia ʻo colitis he hoʻokolohua i kēia manawa a ʻaʻole hoʻohana ākea a ʻike ʻia he maikaʻi.

Pākuʻi paha nā pilikia no FMT i kēia mau mea:

• Nā hopena i ka lāʻau i hāʻawi ʻia iā ʻoe i ke kaʻina hana
• Kaumaha a hoʻomau i ke kahe ʻana i ke kaʻina hana
• Nā pilikia hanu
• Ka hohola ʻana o ka maʻi mai ka mea hāʻawi (inā ʻaʻole hōʻike loiloi ʻia ka mea hāʻawi, he mea laha ʻole ia)
• ʻO ka maʻi i ka manawa o colonoscopy (ʻano liʻiliʻi loa)
• Hoʻopaʻa koko (kākaʻikahi loa)

Lawe paha ka mea hāʻawi i ka laxative i ka pō ma mua o ke kaʻina hana i hiki ai iā lākou ke neʻe i kahi ʻōpū i ke kakahiaka aʻe. E hōʻiliʻili lākou i kahi laulau i loko o kahi kīʻaha maʻemaʻe a lawe mai me lākou i ka lā o ke kaʻina hana.

E kamaʻilio i kāu mea hoʻolako e pili ana i nā maʻi āpau a me nā lāʻau āpau āu e lawe nei. Mai hōʻoki i ka lawe ʻana i nā lāʻau me ka ʻole o ke kamaʻilio ʻana i kāu mea hāʻawi. Pono ʻoe e hōʻoki i ka lawe ʻana i nā lāʻau ʻalopika no 2 a 3 mau lā ma mua o ke kaʻina hana.

Pono paha ʻoe e hāhai i ka papa wai. E noi paha ʻoe e lawe i nā laxatives i ka pō ma mua o ke kaʻina hana. Pono ʻoe e hoʻomākaukau no kahi kolona i ka pō ma mua o FMT. E hāʻawi aku kāu kauka iā ʻoe i nā ʻōkuhi.

Ma mua o ke kaʻina hana, hāʻawi ʻia ʻoe i nā lāʻau e hiamoe ai ʻoe i mea e ʻike ʻole ai ʻoe i kahi hōʻoluʻolu a i ʻole kahi hoʻomanaʻo o ka hoʻāʻo.

E moe ʻoe ma kou ʻaoʻao ma kahi o 2 mau hola ma hope o ke kaʻina hana me ka hopena ma kou ʻōpū. Hāʻawi ʻia iā ʻoe ka loperamide (Imodium) e kōkua i ka hoʻolōʻihi i kou ʻōpū i mau ai ka hopena ma kēia manawa.

E hoʻi ʻoe i ka home i ka lā like o ke kaʻina hana ke hala ʻoe i ka hui ʻana o ka pahu. Pono ʻoe e holo i ka home, no laila e noʻonoʻo e hoʻonohonoho ma mua o ka manawa. Pono ʻoe e hōʻalo i ka hoʻokele, inu wai ʻona, a i ʻole nā ​​hāpai hāpai kaumaha.

Loaʻa paha iā ʻoe kahi fiva haʻahaʻa i ka pō ma hope o ke kaʻina hana. Loaʻa paha ʻoe i ka bloating, gas, flatulence, a me ka constipation no kekahi mau lā ma hope o ke kaʻina hana.

E aʻo aku kāu mea lawelawe iā ʻoe e pili ana i ke ʻano o ka papaʻai a me nā lāʻau e pono ai e lawe ma hope o ke kaʻina hana.

ʻO kēia mālama ola-palekana loa, kūpono a me, kumukūʻai haʻahaʻa. Kōkua ʻo FMT i ka hoʻihoʻi ʻana mai i nā flora maʻamau ma o ka pahu hāʻawi. Kōkua kēia i ka hoʻihoʻi ʻana i kāu hana ʻōpū maʻamau a me ke olakino.

Fecal bacteriotherapy; Ka hoʻoneʻe kolo; Ke kuʻi fecal; C. difficile colitis - fecal transplant; Difficile Clostridium - transplant fecal; ʻO Clostridioides difficile - fecal transplant; Pseudomembranous colitis - fecal transplant

Mahmoud NN, Bleier JIS, Aarons CB, Paulson EC, Shanmugan S, Fry RD. Kolona a me ka pololei. I: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. ʻO Sabiston Textbook of Surgery. 20 ouk. Piladelapia, PA: Elsevier; 2017: chap 51.

ʻO Rao K, Safdar N. Fecal microbiota transplantation no ka mālama ʻana i ka maʻi Clostridium difficile. J Hosp Med. 2016; 11 (1): 56-61. PMID: 26344412 www.ncbi.nlm.nih.gov/pubmed/26344412.

ʻO Schneider A, ʻo Maric L. Fecal microbiota transplantation ma ke ʻano he therapy no ka maʻi ʻōpū. I: Shen B, hoʻoponopono. ʻO ka maʻi hoʻowelawela hoʻowalewale hoʻowalewale. San Diego, CA: Elsevier Academic Press; 2018: chap 28.

Surawicz CM, Brandt LJ. ʻO Probiotics a me ke kanu ʻana o ka microbiota fecal. I: Feldman M, Friedman LS, Brandt LJ, eds. ʻO Sleisenger a me Fordtran's Gastrointestinal a me ka maʻi Liver: Pathophysiology / Diagnosis / Management. 10 o ka lā. Piladelapia, PA: Elsevier Saunders; 2016: chap 130.