Hōʻike DHEA-sulfate

Kū ka DHEA no dehydroepiandrolone. ʻO ia kahi hormone kāne palupalu (androgen) i hana ʻia e nā adrenal glands i nā kāne a me nā wahine. Hoʻomaopopo ka hōʻike DHEA-sulfate i ka nui o DHEA-sulfate i loko o ke koko.

Pono kahi laʻana koko.

ʻAʻole pono kahi hoʻomākaukau kūikawā. Eia nō naʻe, e haʻi i kāu mea mālama ola inā e lawe ana ʻoe i nā wikamina a i ʻole nā ​​mea hoʻohui i piha me DHEA a i ʻole DHEA-sulfate.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.

Hana ʻia kēia ho'āʻo e nānā i ka hana o nā adrenal glands ʻelua. Noho kekahi o kēia mau gland ma luna o kēlā me kēia hakuʻala. ʻO lākou kekahi o nā kumu nui o androgens i nā wahine.

ʻOiai ʻo DHEA-sulfate ka nui o ka hormone i loko o ke kino, ʻaʻole ʻike ʻia kāna hana kikoʻī.

• I nā kāne, ʻaʻole nui ka hopena o ka hormone kāne inā he maʻamau ka pae testosterone.
• I nā wahine, hāʻawi ka DHEA i ka libido maʻamau a me ka leʻaleʻa wahine.
• He hopena paha kā DHEA ma ka ʻōnaehana pale.

Hana pinepine ʻia ka hōʻike DHEA-sulfate i nā wahine e hōʻike i nā hōʻailona o ka nui o nā kāne kāne. ʻO kekahi o kēia mau hōʻailona he loli ke kino kāne, ulu nui o ka lauoho, ʻili aila, huehue, wā kū ʻole, a i ʻole nā ​​pilikia e hāpai ana.

Hana ʻia ia i nā wahine e hopohopo nei e pili ana i ka libido liʻiliʻi a i ʻole ka hōʻemi ʻana i ka leʻaleʻa wahine i loaʻa i nā maʻi pituitary a adrenal gland.

Hana ʻia ka hoʻāʻo i nā keiki e oʻo mua (precocious puberty).

Hiki ke ʻokoʻa nā pae koko maʻamau o DHEA-sulfate e ka moekolohe a me nā makahiki.

ʻO nā pae maʻamau maʻamau no nā wahine:

• Nā makahiki 18 a 19: 145 a 395 micrograms no deciliter (µg / dL) a i ʻole 3.92 a 10.66 micromoles i kēlā me kēia lita (µmol / L)
• Nā makahiki 20 a 29: 65 a 380 µg / dL a i ʻole 1.75 a 10.26 µmol / L
• Nā makahiki 30 a 39: 45 a 270 µg / dL a i ʻole 1.22 a 7.29 µmol / L
• Nā makahiki 40 a 49: 32 a 240 µg / dL a i ʻole 0.86 a 6.48 µmol / L
• Nā makahiki 50 a 59:59: 26 a 200 µg / dL a i ʻole 0.70 a 5.40 µmol / L
• Nā makahiki 60 a 69: 13 a 130 µg / dL a i ʻole 0.35 a 3.51 µmol / L
• Nā makahiki 69 a ʻoi aku: 17 a 90 µg / dL a i ʻole 0.46 a 2.43 µmol / L

ʻO nā pae maʻamau maʻamau no nā kāne:

• Nā makahiki 18 a 19: 108 a 441 µg / dL a i ʻole 2.92 a 11.91 µmol / L
• Nā makahiki 20 a 29: 280 a 640 µg / dL a i ʻole 7.56 a 17.28 µmol / L
• Nā makahiki 30 a 39: 120 a 520 µg / dL a i ʻole 3.24 a i 14.04 µmol / L
• Nā makahiki 40 a 49: 95 a 530 µg / dL a i ʻole 2.56 a i 14.31 µmol / L
• Nā makahiki 50 a 59:59: 70 a 310 µg / dL a i ʻole 1.89 a 8.37 µmol / L
• Nā makahiki 60 a 69: 42 a 290 µg / dL a i ʻole 1.13 a 7.83 µmol / L
• Nā makahiki 69 a ʻoi aku: 28 a 175 µg / dL a i ʻole 0.76 i 4.72 olmol / L

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā mea hoʻohālikelike like ʻole. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

Hoʻonui ʻia ka DHEA-sulfate ma muli o:

• ʻO kahi maʻi kūlohelohe maʻamau i kapa ʻia ʻo hyperplasia adrenal congenital.
• ʻO kahi tumo o ka adrenal gland, hiki ke lilo i benign a i ʻole he maʻi ʻaʻai.
• ʻO kahi pilikia maʻamau i nā wahine ma mua o 50, i kapa ʻia ʻo polycystic ovary syndrome.
• Hoʻololi ke kino o kahi kaikamahine i ka wā ʻōpio ma mua o ka maʻamau.

ʻO ka emi ʻana o DHEA sulfate ma muli o:

• Nā maʻi o ka adrenal gland e hana ma lalo o ka maʻamau o nā adrenal hormones, me ka lawa ʻole o adrenal a me ka maʻi ʻo Addison
• ʻAʻole hana ka pituitary gland i nā huina maʻamau o kāna mau hormones (hypopituitarism)
• Lawe i nā lāʻau ʻo glucocorticoid

Hōʻalo mau nā pae DHEA me ka makahiki i nā kāne a me nā wahine. ʻAʻohe mea hōʻike paʻa i ka lawe ʻana i nā mea hoʻopili DHEA e pale ai i nā kūlana e pili ana i ka ʻelemakule.

Aia kahi pilikia iki i ka lawe ʻia ʻana o kou koko. Hoʻohālikelike nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka loaʻa ʻana o kahi laʻana koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (kūkulu koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Serum DHEA-sulfate; Hōʻike Dehydroepiandrolone-sulfate; DHEA-sulfate - serum

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ʻO Nakamoto J. Endocrine hoʻāʻo. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 154.

Nerenz RD, Jungheim E, Gronowksi AM. Reproductive endocrinology a me nā maʻi e pili pū ana. I: Rifai N, ed. ʻO Tietz Textbook of Clinical Chemistry a me nā Molecular Diagnostics. ʻElua huaʻōlelo St Louis, MO: Elsevier; 2018: chap 68.

ʻO Rosenfield RL, Barnes RB, Ehrmann DA. ʻO Hyperandrogenism, hirsutism, a me polycystic ovary syndrome. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 133.

van den Beld AW, Lamberts SWJ. Endocrinology a me ka ʻelemakule. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 28.