Hōʻike ʻo Erythropoietin

ʻO ke ana o ka erythropoietin e ana i ka nui o kahi hōmona i kapa ʻia ʻo erythropoietin (EPO) i ke koko.

ʻ tellslelo ka hōmona i nā hunaola i ka iwi o ka iwi e hana i nā hunaola ʻulaʻula hou. Hana ʻia ʻo EPO e nā hunaola i ka puʻupaʻa. Hoʻokuʻu kēia mau huna i ka EPO ke haʻahaʻa ka pae o ka oxygen.

Pono kahi laʻana koko.

ʻAʻole pono kahi hoʻomākaukau kūikawā.

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻO ka manaʻo ʻē aʻe he prick a wīwī wale paha ka manaʻo. Ma hope, aia paha kekahi ʻōkā.

Hiki ke hoʻohana ʻia kēia hoʻokolohua e kōkua ai e hoʻoholo i ke kumu o ka anemia, polycythemia (helu ʻulaʻula koko kiʻekiʻe) a i ʻole nā ​​maʻi ʻono pūpū ʻē aʻe.

Hoʻololi kahi hoʻololi i nā hunaola ʻulaʻula i ka hoʻokuʻu ʻia o EPO. ʻO kahi laʻana, ʻo ka poʻe me ka anemia he kakaikahi nā koko ʻulaʻula, no laila e hoʻonui ʻia ka EPO.

ʻO ka pae maʻamau ʻo 2.6 a 18.5 milliunits ma ka milliliter (mU / mL).

ʻO nā laʻana ma luna he ana maʻamau no nā hopena o kēia mau hoʻāʻo. Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā ​​hoʻāʻo i nā laʻana like ʻole. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu hopena hoʻokolohua kikoʻī.

Hoʻonui ʻia ka pae EPO ma muli o ka polycythemia lua. Kēia mea he overproduction o ʻulaʻula keena kala e kū i ka pane i kahi hanana e like me ka haʻahaʻa pae o ka oxygen pae. Kū paha ke ʻano ma nā wahi kiʻekiʻe a i ʻole, kākaʻikahi, ma muli o kahi tumo e hoʻokuʻu iā EPO.

Hiki ke ʻike ʻia ka pae EPO haʻahaʻa ma mua o ka maʻamau i ka holo pono ʻole ʻana o ka puʻuwai, anemia o ka maʻi mau, a i ʻole polycythemia vera.

ʻO nā pōpilikia e pili ana i ke kahe ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Serry erythropoietin; EPO

ʻO Bain BJ. Hoʻopili ke koko ākea. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 148.

Kaushansky K. Hematopoiesis a me nā mea ulu hematopoietic. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 147.

Kremyanskaya M, Najfeld V, Mascarenhas J, Hoffman R. The polycythemias. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2018: chap 68.

Kumar V, Abbas AK, Aster JC. ʻO ke koko a me nā maʻi kahe o ke kahe. I: Kumar P, Clark M, eds. ʻO Kauka Lapaʻau ʻo Kumar lāua ʻo Clarke. 9th ed. Piladelapia, PA: Elsevier; 2017: chap 14.