Helu RBC
ʻO kahi helu RBC kahi hōʻike koko e ana i ka nui o nā hunaola ʻulaʻula (RBC) iā ʻoe.
Loaʻa i nā RBC hemoglobin, e hāpai ana i ka oxygen. Aia ka nui o ka oxygen o kāu mau pūnaewele i ka nui o nā RBC āu a me ka maikaʻi o ka hana.
Pono kahi laʻana koko.
ʻAʻole pono kahi hoʻomākaukau kūikawā.
Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ka ʻūlū iki. Hele koke kēia.
ʻO ka helu RBC kahi ʻaneʻane mau o kahi hōʻike o ka helu piha o ke koko (CBC).
Hiki i ke hōʻike ke kōkua i ke kuhi ʻana i nā ʻano anemia like ʻole (helu haʻahaʻa o nā RBC) a me nā kūlana ʻē aʻe e pili ana i nā hunaola ʻulaʻula.
ʻO nā kūlana ʻē aʻe e koi ai i kahi helu RBC:
- ʻO ka maʻi e hōʻino ai i nā kīʻaha koko (Alport Syndrome)
- Ka maʻi ʻaʻai koko keʻokeʻo (Waldenström macroglobulinemia)
- ʻO ka maʻi kahi e wāwahi ai nā hunaola ʻulaʻula ma mua o ka maʻamau (paroxysmal nocturnal hemoglobinuria)
- ʻO ka maʻi pūpū iwi kahi e pani ʻia ka momona e kaʻiʻo makaʻu (myelofibrosis)
ʻO nā pae RBC maʻamau ʻo:
- Kāne: 4.7 a 6.1 miliona mau huna ma kēlā me kēia microliter (cells / mcL)
- Wahine: 4.2 a 5.4 miliona mau pūnaewele / mcL
ʻO nā pae ma luna nā ana maʻamau no nā hopena o kēia mau hoʻāʻo. Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā hoʻāʻo i nā laʻana like ʻole. E kamaʻilio me kāu mea mālama ola e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.
ʻO ke kiʻekiʻe ma mua o nā helu maʻamau o RBC ma muli o:
- Puhi paka
- Ka pilikia me ka naʻau o ka hanana a me ka hana i kū i ka wā hānau (congenital puʻuwai maʻi)
- Hewa o ka ʻaoʻao ʻākau o ka puʻuwai (cor pulmonale)
- Dehydration (ʻo kahi laʻana, mai ka maʻi pākī nui)
- Tumo hakuʻala (carenaloma pūnana renal)
- ʻO ke kiʻekiʻe o ka oxygen koko haʻahaʻa (hypoxia)
- Pākuʻi a mānoanoa paha o nā akemāmā (pulmonary fibrosis)
- ʻO ka maʻi iwi iwi e hoʻonui ai i ka RBCs (polycythemia vera)
E hoʻonui ana kāu helu RBC no nā pule he nui inā ʻoe i kahi kiʻekiʻe kiʻekiʻe.
ʻO nā lāʻau i hiki ke hoʻonui i ka helu RBC:
- ʻO nā steroid Anabolic
- Erythropoietin
- Gentamicin
Nā helu haʻahaʻa ma mua o ka maʻamau o nā RBC ma muli o:
- Anemia
- Kahena
- Hoka iwi iwi (ʻo kahi laʻana, mai ka pāhawewe, toxins, a i ʻole tumo)
- Ka nele o kahi hōmona i kapa ʻia ʻo erythropoietin (i hoʻokumu ʻia e ka maʻi puʻupaʻa)
- Luku ʻia ʻo RBC (hemolysis) ma muli o ke transfusion, ʻeha o ke kīʻaha koko, a i ʻole kumu ʻē aʻe
- Leukemia
- Kaʻai pono ʻole
- ʻO ka maʻi ʻaʻai pūpū i kapa ʻia he myeloma he nui
- ʻO ka hao liʻiliʻi, keleawe, folic acid, wikamina B6, a i ʻole vitamin B12 i ka papaʻai
- Nui loa ka wai i ke kino (overhydration)
- Hapai keiki
ʻO nā lāʻau i hiki ke hoʻēmi i ka helu RBC:
- Nā lāʻau Chemotherapy
- ʻO Chloramphenicol a me kekahi mau lāʻau ʻaloʻalo ʻē aʻe
- Nā Hydantoins
- Methyldopa
- Nā lāʻau anti-inflammatory nonsteroidal (NSAIDs)
- Quinidine
ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.
ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi, akā hiki ke hoʻopili ʻia:
- Kahe nui ke koko
- Pāleʻale a ʻoluʻolu paha
- Nā punctures he nui e ʻimi i nā uaua
- Hematoma (kūkulu koko ma lalo o ka ʻili)
- Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)
Helu helu ʻErythrocyte; Helu ʻulaʻula koko; Anemia - helu RBC
- Hōʻaʻo koko
- Nā mea i hana ʻia o ke koko
- Nā hoʻāʻo koko kiʻekiʻe
Chernecky CC, Berger BJ. ʻAla koko ʻulaʻula (RBC) - koko. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo Piladelapia, PA: Elsevier; 2013: 961-962.
ʻO Gallagher PG. Hemolytic anemias: ʻulaʻula koko membrane a me nā kīnā metabolik. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 152.
ʻO M. Anemia liʻiliʻi. I: Cameron P, Little M, Mitra B, Deasy C, eds. Puka o ka Medicine Emergency Emergency. 5th lā. Piladelapia, PA: Elsevier; 2020: chap 13.
ʻO RT. Hele i nā anemias. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 149.