5-HIAA mimi hoʻāʻo
5-HIAA kahi hōʻike mimi e ana i ka nui o 5-hydroxyindoleacetic acid (5-HIAA). ʻO 5-HIAA kahi huahana breakdown o kahi hormone i kapa ʻia serotonin.
Hōʻike kēia hōʻike i ka nui o 5-HIAA e hana nei ke kino. He ala ia e ana i ka nui o ka serotonin i loko o ke kino.
Pono kahi laʻana mimi he 24 mau hola. Pono ʻoe e hōʻiliʻili i kāu mimi ma kahi o 24 mau hola i kahi pahu i hāʻawi ʻia e ka hale hana. E haʻi aku kāu mea mālama ola iā ʻoe pehea e hana ai i kēia. E hahai pololei i nā ʻōkuhi.
E aʻo aku kāu mea hāʻawi iā ʻoe, inā pono, e hōʻoki i ka lawe ʻana i nā lāʻau e hoʻopilikia paha i ka hōʻike.
ʻO nā lāʻau e hiki ke hoʻonui i nā ana o 5-HIAA me ka acetaminophen (Tylenol), acetanilide, phenacetin, glyceryl guaiacolate (i loaʻa i nā syrups he nui), methocarbamol, a me reserpine.
ʻO nā lāʻau e hiki ke hoʻemi i nā ana o 5-HIAA me heparin, isoniazid, levodopa, monoamine oxidase inhibitors, methenamine, methyldopa, phenothiazines, a me nā antidepressants tricyclic.
E haʻi ʻia ʻoe ʻaʻole e ʻai i kekahi mau meaʻai no 3 mau lā ma mua o ka hoʻāʻo. ʻO nā meaʻai e hiki ke hoʻopilikia i nā ana o 5-HIAA me nā plum, nā paina, nā maiʻa, eggplant, nā ʻōmato, nā avocados, a me nā walnuts.
Pili ka hōʻike i ka urination maʻamau wale nō, a ʻaʻohe pilikia.
Ana kēia hōʻike i ke kiʻekiʻe o 5-HIAA i ka mimi. Hana pinepine ʻia e ʻike i kekahi mau tumors i ka digestive tract (carcinoid tumors) a me ka nānā ʻana i ke ʻano o ke kanaka.
Hiki ke hoʻohana ʻia ka hōʻike mimi e kuhikuhi i kahi maʻi i kapa ʻia ʻo mastocytosis ʻōnaehana a me kekahi mau tumors o ka hōmona.
ʻO ka pae maʻamau ʻo 2 a 9 mg / 24h (10.4 a 46.8 µmol / 24h).
Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole nā hoʻāʻo i nā laʻana like ʻole. E kamaʻilio i kāu mea hāʻawi e pili ana i ke ʻano o kāu mau hopena hōʻike.
Nā hopena kūpono ʻole ma muli o:
- Nā tumors o ka ʻōnaehana endocrine a i ʻole nā tumors carcinoid
- Hoʻonui ʻia nā hunaola pale i kapa ʻia nā mast mast i loko o kekahi mau ʻāpana (mastocytosis ʻōnaehana)
ʻAʻohe pilikia me kēia hōʻike.
HIAA; 5-hydroxyindole acetic acid; Serotonin metabolite
Chernecky CC, Berger BJ. H. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo Piladelapia, PA: Elsevier Saunders; 2013: 660-661.
ʻO Wolin EM, ʻo Jensen RT. Nā Tumora Neuroendocrine. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 219.