ʻO ka wahine pili i ka moekolohe

ʻO ka mea nui i pili i ka moekolohe kahi ala maʻamau ʻole e hiki ke hoʻoiho ʻia kahi ʻano a i ʻole kahi maʻi i waena o nā ʻohana. Hiki i hoʻokahi ʻāpana ʻokoʻa ma ka X chromosome ke kumu i kahi maʻi nui i pili i ka wahine.

Pili nā huaʻōlelo a me nā kumuhana e pili ana:

• ʻO Autosomal ka mea nui
• Hoʻomaha hou ʻo Autosomal
• ʻO Chromosome
• ʻO Gene
• Ka hoʻoilina a me nā maʻi
• Ka hoʻoilina hoʻoilina
• Hoʻomaha recessive pili wahine

ʻO ka hoʻoilina o kahi maʻi kikoʻī, kūlana, a i ʻole ke ʻano e pili ana i ke ʻano o ka chromosome e hoʻopili ʻia. Hiki iā ia ke lilo i chromosome autosomal a i ʻole chromosome wahine. Aia nō ia i ka hilinaʻi a i ʻole recessive paha ke ʻano. Ua hoʻoili ʻia nā maʻi e pili ana i ka moekolohe ma o kekahi o nā chromosome wahine, ʻo ia nā X a me Y chromosome.

Kū ka hoʻoilina Dominant ke hiki i kahi ʻāpana ʻokoʻa mai kekahi makua ke kumu i kahi maʻi, ʻoiai ʻo kahi ʻāpana kūlike mai nā mākua ʻē aʻe ka maʻamau. ʻO ka ʻāpana ʻokoʻa ka mea nui ma luna o ka ʻelua hui.

No kahi maʻi koʻikoʻi X-hoʻopili ʻia: Inā hāpai ka makuakāne i ka gen X maʻamau, e hoʻoilina ʻia kāna mau kaikamahine āpau i ka maʻi a ʻaʻohe o kāna mau keikikāne e loaʻa i kēia maʻi. ʻO ia no ka mea hoʻoilina mau nā kaikamahine i ka chromosome X o ko lākou makuakāne. Inā hāpai ka makuahine i ka gen X maʻamau, ʻo ka hapalua o kā lākou mau keiki (kaikamahine a me nā keiki kāne) e ili i ka maʻi maʻi.

ʻO kahi laʻana, inā ʻehā mau keiki (ʻelua mau keikikāne a ʻelua mau kaikamahine) a pili ka makuahine (hoʻokahi maʻi X kona a loaʻa ka maʻi) akā ʻaʻohe o ka makuakāne ka gen X maʻamau, ʻo nā mea i manaʻo ʻia:

• ʻElua mau keiki (hoʻokahi kaikamahine a hoʻokahi keikikāne) e loaʻa i kēia maʻi
• ʻAʻole ʻelua keiki (hoʻokahi kaikamahine a hoʻokahi keikikāne) e loaʻa i kēia maʻi

Inā he ʻehā mau keiki (ʻelua mau keikikāne a ʻelua mau kaikamahine) a ua pili ka makuakāne (hoʻokahi kona ʻano X a loaʻa ka maʻi) akā ʻaʻole ka makuahine, ʻo nā mea i manaʻo ʻia:

• ʻElua mau kaikamahine e loaʻa i kēia maʻi
• ʻAʻole ʻelua keiki kāne e loaʻa i kēia maʻi

ʻAʻole kēia manaʻo i nā keiki e hoʻoilina i ka X maʻamau e hōʻike i nā hōʻailona koʻikoʻi o ka maʻi. ʻO ka manawa o ka hoʻoilina hou me kēlā me kēia hapai, no laila ʻaʻole kēia mau mea i manaʻo ʻia e kū maoli i kahi ʻohana. ʻO kekahi mau maʻi kūpilikiʻi X i koʻikoʻi loa i hiki i nā kāne me ka maʻi genetika e make ma mua o ka hānau ʻana. No laila, e hoʻonui ʻia paha ka nui o nā hāʻule i loko o ka ʻohana a i ʻole nā ​​keiki kāne liʻiliʻi ma mua o ka mea i manaʻo ʻia.

Hoʻoilina - pili wahine pili i ka moekolohe; Genetics - pili wahine i pili i ka wahine; Hoʻohui X-pili; Hoʻohui Y-loea

• Nā Genetics

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Gregg AR, Kuller JA. Kanaka genetics a me nā lauana o ka hoʻoilina. I: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, eds. ʻO Medicine a Maternal-Fetal a Creasy a me Resnik: Nā Manaʻo a me ka Hoʻomeheu. 8th ed. Piladelapia, PA: Elsevier; 2019: chap 1.

ʻO Jorde LB, Carey JC, Bamshad MJ. Pili-pili a me nā ʻano hana ʻole hoʻoilina o ka hoʻoilina. I: ʻO Jorde LB, Carey JC, Bamshad MJ, hua. Nā Genetics Lapaʻau. ʻElua huaʻōlelo Piladelapia, PA: Elsevier; 2020: chap 5.

Korf BR. Nā loina o nā genetics. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 35.