ʻO Sjögren maʻi

ʻO Sjögren Syndrome kahi maʻi autoimmune kahi e luku ʻia ai nā glands e hana ai i ka waimaka a me ka saliva. ʻO kēia ke kumu o ka waha maloʻo a me nā maka maloʻo. Hiki paha i ke ʻano ke hoʻololi i nā ʻāpana ʻē aʻe o ke kino, e like me nā puʻupaʻa a me nā akemāmā.

ʻAʻole ʻike ʻia ke kumu o ka maʻi Sjögren. He maʻi maʻi autoimmune ia. ʻO ke kumu o ka hōʻeha ʻana o ke kino i nā mea olakino ma ke kuhihewa Kū pinepine pinepine ka maʻi maʻi i nā wahine mai 40 a 50. He kākaʻikahi kēia i nā keiki.

Hoʻomaopopo ʻia ka maʻi Sjögren Syndrome e like me nā maka maloʻo a me ka waha maloʻo me ka ʻole o kahi maʻi autoimmune.

Kū kekahi ka maʻi Sjögren Secondary me kahi maʻi autoimmune ʻē aʻe, e like me:

• Rheumatoid arthritis (RA)
• ʻO ka lupus erythematosus ʻōnaehana
• Scleroderma
• ʻO Polymyositis
• Hiki i ka Hepatitis C ke hoʻopili i nā aʻa salivary a like me ka maʻi Sjögren
• Hiki ke nānā aku i ka maʻi IgG4 e like me Sjogren Syndrome a pono e noʻonoʻo ʻia

ʻO nā maka maloʻo a me ka waha maloʻo nā hōʻailona maʻamau o kēia maʻi.

Nā ʻōuli o ka maka:

• Maka maka
• Ke manaʻo nei aia kekahi mea i ka maka

Nā ʻōuli o ka waha a me ka ʻāʻī:

• Pilikia i ka ale ʻana a i ʻole ka ʻai ʻana i nā meaʻai maloʻo
• Loaʻa o ke ʻano o ka ʻono
• Pilikia i ka ʻōlelo ʻana
• Mīkini mānoanoa a stringy paha
• ʻEha nā waha a ʻeha paha
• ʻO ka palaho o ka niho a me ka mumū
• Hoarseness

Hiki i nā ʻōuli ʻē aʻe ke:

• Ka luhi
• Fiva
• Hoʻololi i ke kala o nā lima a me nā wāwae me ke anuanu (Raynaud hanana)
• ʻEha puʻupuʻu a hui pū paha
• Nūhū pehu
• ʻ Skinhū ʻili
• Pōpō a me ka ʻeha ma muli o ka neuropathy
• Cough and shortness of breath ma muli o ka maʻi maʻi
• Paʻi kuʻi ʻole
• ʻO Nusea a me ka puʻuwai puʻuwai
• ʻO ka maloʻo a me ka urination ʻeha

E hoʻopau ʻia kahi hōʻike kino holoʻokoʻa. Hōʻike ka hōʻike i nā maka maloʻo a me ka waha maloʻo. Hiki paha i nā ʻeha waha, nā niho pala a i ʻole ka mumū. Kū kēia ma muli o ka maloʻo o ka waha. E nānā kāu mea olakino i kou waha no ka maʻi fungus (candida). Hiki i ka ʻili ke hōʻike i kahi wīwī, kūleʻa paha ka hoʻokolohua māmā, e palpated ka ʻōpū no ka hoʻonui ʻana o ke ake. E nānā ʻia nā ami no ka maʻi kō. E nānā ka neuro hōʻike i nā hemahema.

Loaʻa paha iā ʻoe kēia mau hoʻāʻo i hana ʻia:

• Hoʻopau i ke kemika o ke koko me nā enzymes ate
• Helu piha ke koko me ka ʻokoʻa
• Urinalysis
• Nā hoʻāʻo antinuclear antibodies (ANA)
• Anati-Ro / SSA a me anti-La / SSB nā mea pale mūhā
• ʻLelo Rheumatoid
• Hōʻoia no cryoglobulins
• Nā pae hoʻokō
• Palapala uila electrostoresis
• Hōʻike no ka maʻi hepa C a me HIV (inā ma ka makaʻu)
• Nā hoʻāʻo thyroid
• Hōʻike Schirmer o ka hana waimaka
• ʻO ke kiʻi ʻana o ka momona salivary: e ka ultrasound a i ʻole e MRI
• ʻO ka biopsy gland salivary
• ʻO ka biopsy o ka ʻili inā loaʻa kahi ʻōhū
• ʻO ka hoʻokolokolo ʻana i nā maka e ka ophthalmologist
• Pākuʻi x-ray

ʻO ka pahuhopu e hoʻomaha i nā ʻōuli.

• Hiki ke mālama ʻia nā maka maloʻo me nā waimaka kuʻi, nā hamo lubricating maka, a i ʻole ka wai cyclosporine.
• Inā loaʻa ʻo Candida, hiki ke mālama ʻia me ka miconazole kō ʻole a me nā hoʻomākaukau nystatin.
• Hiki ke waiho i nā plugina liʻiliʻi i nā auwai kahe waimaka e kōkua i ka waimaka e noho ma ka maka o ka maka.

ʻO nā lāʻau lapaʻau antirheumatic (DMARD) e like me nā mea i hoʻohana ʻia no RA e hoʻomaikaʻi ai i nā hōʻailona o ka maʻi Sjögren. Hoʻopili kēia i nā tumrosis tumrosis factor (TNF) e kāohi ana i nā lāʻau e like me Enbrel, Humira a me Remicaide.

ʻO kekahi mau mea hiki iā ʻoe ke hana e hōʻoluʻolu i nā hōʻailona me:

• Hoʻomaʻamaʻa wai i ka lā holoʻokoʻa
• E nauʻu i ka kāpili kō ʻole
• Hōʻalo i nā lāʻau e hiki ai ke hoʻomaloʻo i ka waha, e like me antihistamines a me nā decongestants
• Hōʻalo i ka waiʻona

E kamaʻilio me kāu kauka niho e pili ana:

• Holoi ka waha e pani i nā minelala i kou mau niho
• Mea pani hakahaka
• ʻO nā lāʻau e kōkua i kāu mau mū salivary e hana i nā kuha hou aʻe

E pale aku i nā palaho niho i hoʻokumu ʻia e ka maloʻo waha:

• Palaki a pulupulu pinepine i kou mau niho
• E kipa aku i ka kauka niho no ka nānā maʻamau a me ka hoʻomaʻemaʻe

ʻAʻole hoʻoweliweli pinepine ka maʻi. Pili ka hopena i nā maʻi ʻē aʻe āu.

Aia ka nui o ka makaʻu no ka lymphoma a me ka make mua ke hana nui ʻo Sjögren syndrome no ka manawa lōʻihi, a ʻo nā poʻe me ka vasculitis, nā mea hoʻoliʻiliʻi haʻahaʻa, a me nā cryoglobulins.

Komo pū nā pilikia:

• Poino i ka maka
• Kahua niho kahua niho
• Nā hōʻino kīwī (kākaʻikahi)
• Lymphoma
• Maʻi pulmonary
• Vasculitis (kākaʻikahi)
• Neuropathy
• Huʻi ʻōpū

Kāhea i kāu mea hāʻawi inā hoʻomōhala ʻoe i nā ʻōuli o Sjögren syndrome.

Xerostomia - Sjögren maʻi; Keratoconjunctivitis sicca - Sjögren; ʻO Synca Syndrome

• Nā Antibodies

Baer AN, Alevizos I. Sjögren maʻi maʻi. I: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. ʻEpekema 7 Piladelapia, PA: Elsevier; 2019: chap 147.

ʻO Mariette X. Sjögren maʻi maʻi. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 268.

Seror R, Bootsma H, Saraux A, et al. ʻO ka wehewehe ʻana i nā hana maʻi a me ka hoʻomaikaʻi maikaʻi ʻana i ka maʻi i ka maʻi mua o Sjögren's syndrome me ka EULAR primary Sjögren's syndrome maʻi hana (ESSDAI) a me nā hōʻike i hōʻike ʻia e ka poʻe maʻi (ESSPRI). ʻO Ann Rheum Dis. 2016; 75 (2): 382-389. PMID: 25480887 www.ncbi.nlm.nih.gov/pubmed/25480887.

Singh AG, Singh S, Matteson EL. Ka helu, nā kumu pilikia a me nā kumu o ka make ma nā mea maʻi me Sjögren's Syndrome: kahi loiloi ʻōnaehana a me meta-analysis o nā cohort haʻawina. Rheumatology (Oxford). 2016; 55 (3): 450-460. PMID: 26412810 www.ncbi.nlm.nih.gov/pubmed/26412810.

ʻO MD Turner Nā hōʻike waha o nā maʻi ʻōnaehana. I: Flint PW, Haughey BH, Lund V, et al, eds. ʻO Cummings Otolaryngology. ʻElua huaʻōlelo Piladelapia, PA: Elsevier Saunders; 2015: chap 14.