Nā Agena Prokinetic

Anter

• Nā ʻano Prokinetics
• ʻO Bethanechol
• ʻO Cisapride
• Metoclopramide

I loko o kahi esophagus kanaka olakino, ke ʻānai nei i ka peristalsis mua. ʻO kēia nā kuʻikahi e hoʻoneʻe i kāu meaʻai i lalo i kāu esophagus a ma o ke koena o kāu ʻōnaehana digestive. Ma ka hoʻololi, hoʻonāukiuki ka reflux gastroesophageal i kahi nalu ʻelua o nā muscular contractions e hoʻomaʻemaʻe i ka esophagus, e hoʻokau nei i ka meaʻai i lalo ma o ka sphincter esophageal haʻahaʻa (LES) a i loko o ka ʻōpū.

Eia nō naʻe, i kekahi poʻe, hoʻomaha a wehe wehe paha ka LES, e ʻae ana i nā ʻōpū, me nā waikawa, e komo hou i ka esophagus. Kapa ʻia kēia he reflux waikawa a alakaʻi paha i nā ʻōuli e like me ka puʻuwai.

ʻO nā ʻākena Prokinetic, a i ʻole prokinetics, nā lāʻau e kōkua i ka mālama ʻana i ka reflux acid. Kōkua nā Prokinetics i ka hoʻoikaika ʻana i ka sphincter esophageal haʻahaʻa (LES) a hana i nā mea o ka ʻōpū e ninini wikiwiki. ʻAe kēia i ka liʻiliʻi o ka manawa no ka reflux acid.

I kēia lā, hoʻohana pinepine ʻia nā prokinetics me nā maʻi reflux gastroesophageal (GERD) a i ʻole nā ​​lāʻau heartburn, e like me nā mea pale proton pump (PPI) a i ʻole nā ​​H2 receptor blockers. ʻAʻole like me kēia mau lāʻau reflux waikawa ʻē aʻe, ʻoi aku ka palekana, palekana paha nā prokinetics, a i ʻole weliweli paha, nā hopena ʻaoʻao. Hoʻohana wale ʻia lākou ma nā hihia koʻikoʻi o GERD.

ʻO kahi laʻana, hiki ke hoʻohana ʻia nā prokinetics e mālama i ka poʻe i loaʻa i ka maʻi kōkō e pili ana i ka insulin, a i ʻole nā ​​pēpē a me nā keiki me ka ʻōlohelohe o ka ʻōpū a i ʻole ka constipation koʻikoʻi e pane ʻole i nā ʻano lāʻau ʻē aʻe.

Nā ʻano Prokinetics

ʻO Bethanechol

ʻO Bethanechol (Urecholine) kahi lāʻau e hoʻonāukiuki i ka pākeke a kōkua iā ʻoe e hele i ka mimi inā pilikia ʻoe i ka hemo ʻana i kāu ʻōpū. Kōkua ia i ka hoʻoikaika ʻana i ka LES, a wikiwiki ka hakahaka o ka ʻōpū. Mālama pū kekahi ia i ka nausea a me ka luaʻi. Loaʻa ia i ka papa papa.

Eia nō naʻe, e hoʻonui ʻia paha kona pono e nā hopena ʻaoʻao pinepine. Hiki i nā hopena ʻaoʻao ke hoʻopili i:

• hopohopo
• kaumaha
• hiamoe
• luhi
• nā pilikia kino e like me ka neʻe ʻole ʻana a me nā spasms Muscle

ʻO Cisapride

Hana ʻo Cisapride (Propulsid) ma nā mea loaʻa nā serotonin i ka ʻōpū. Hoʻohana nui ʻia ia e hoʻomaikaʻi i ke kani o nā mākala i ka LES. Eia nō naʻe, no ka hopena o ka hopena, e like me ka puʻuwai kūlike ʻole, ua kāpae ʻia ia mai ka mākeke i nā ʻāina he nui, e like me ʻAmelika Hui Pū ʻIa. Ua manaʻo ʻia he maikaʻi loa i ka mālama ʻana iā GERD ma ke ʻano he H2 receptor blockers e like me famotidine (Pepcid). Hoʻohana mau ʻia ʻo Cisapride i nā lāʻau lapaʻau lāʻau.

Metoclopramide

ʻO Metoclopramide (Reglan) kahi mea hoʻohana prokinetic i hoʻohana ʻia e mālama iā GERD ma o ka hoʻomaikaʻi ʻana i ka hana muscle i ka gastrointestinal tract. Loaʻa ia i nā papa ʻelua a me nā ʻano wai. E like me nā prokinetics ʻē aʻe, keakea ʻia ka pono o ka metoclopramide e nā hopena ʻino.

Hiki i nā hopena ʻaoʻao ke hoʻonui i ka makaʻu o nā kūlana neurological e like me tardive dyskinesia, kahi e kumu ai i nā neʻe hou ʻole ʻana. Ua ʻike ʻia kēia mau hopena i ka poʻe i koe i ka lāʻau no ʻekolu mau mahina. Pono e akahele ka poʻe e lawe ana i ka metoclopramide i ka wā e hoʻokele a hana ana paha i nā mīkini kaumaha a i ʻole nā ​​pono pono.

E hana pū me kāu kauka e ʻike i kahi hoʻolālā mālama kūpono iā ʻoe. E mālama pono i nā kuhikuhi a kāu kauka i hāʻawi ai iā ʻoe. Kāhea i kāu kauka inā manaʻo ʻoe ua hana kāu mau lāʻau i nā hopena maikaʻi ʻole.