Eia ka hana me ka hāʻawi ʻana i ka Plasma Convalescent no nā maʻi maʻi COVID-19

Anter

• No laila, he aha ka Convalescent Plasma Therapy, pololei?
• ʻO wai ka mea hiki ke hāʻawi i ka plasma Convalescent no COVID-19?
• He aha ka hāʻawi ʻana i ka plasma Convalescent?
• Nānā no

Mai ka hopena o Malaki, ua hoʻomau ka maʻi maʻi coronavirus i ke aʻo ʻana i ka lāhui - a me ka honua - he pūʻali holoʻokoʻa o nā huaʻōlelo hou: ka hele ʻana i ka nohona, nā lako pale pilikino (PPE), ka hoʻopili ʻana i ka huli ʻana, e inoa wale i kekahi. Me he mea lā me kēlā me kēia lā e hala ana o ka maʻi maʻi (e like me ka mea mau loa) aia kahi hoʻomohala hou e hāʻawi ana i kahi posse maoli o nā huaʻōlelo e hoʻohui i ka puke wehewehe COVID-19 e ulu mau nei. ʻO kekahi o nā mea hou i hoʻohui ʻia i kāu huaʻōlelo waiwai nui? ʻO ka lāʻau plasma convalescent.

ʻAʻole kamaʻāina? E wehewehe au…

Ma ʻAukake 23, 2020 ua ʻae ka US Food and Drug Administration (FDA) i ka hoʻohana ʻana i ka hoʻohana ʻana i ka plasma convalescent - ka ʻāpana waiwai nui o ke koko i lawe ʻia mai nā mea maʻi COVID-19 i hoʻōla ʻia - no ka mālama ʻana i nā hihia coronavirus koʻikoʻi. A laila, ʻoi aku ma mua o hoʻokahi pule ma hope, i ka lā 1 Kepakemapa, ua hui pū ka COVID-19 Treatment Guidelines Panel, kahi ʻāpana o ka National Institutes of Health (NIH), i ke kamaʻilio ʻana, me ka ʻōlelo ʻana ʻaʻole lawa ka ʻikepili e ʻōlelo ai no ka hoʻohana ʻana a i ʻole. o ka plasma convalescent no ka mālama ʻana i ka COVID-19.

Ma mua o kēia pāʻani, ua hāʻawi ʻia ka plasma convalescent i nā mea maʻi maʻi COVID-19 ma o ka Mayo Clinic-led Expanded Access Program (EAP), e koi ana i ke kau inoa kauka i mea e noi ai i ka plasma no nā maʻi, e like me ka FDA. I kēia manawa, ke hele nei i mua, ua pau ka EAP a ke hoʻololi ʻia nei e ka FDA's Emergency Use Authorization (EUA), ka mea e hiki ai i nā kauka a me nā haukapila ke noi i ka plasma me ka ʻole o ka hoʻokō ʻana i kekahi mau koina kākau inoa. Akā, e like me ka mea i hōʻike ʻia e ka ʻōlelo hou a ka NIH, pono ka noiʻi hou aʻe ma mua o ka hiki i kekahi ke ʻōlelo maʻamau (a palekana) i ka convalescent plasma therapy ma ke ʻano he mālama hilinaʻi o COVID-19.

ʻOi aku ka maʻalahi o ka therapy plasma Convalescent ma mua o ka hiki ke mālama ʻia no COVID-19 ma US, akā he aha ia? A pehea ʻoe e hāʻawi ai i ka plasma convalescent no nā maʻi maʻi COVID-19? Ma mua, nā mea a pau e pono ai ʻoe e ʻike.

No laila, he aha ka Convalescent Plasma Therapy, pololei?

ʻO ka mea mua, he aha ka plasma convalescent? ʻO Convalescent (ka inoa a me ka inoa) e pili ana i ka mea e ola ana mai kahi maʻi, a ʻo ka plasma ka ʻāpana melemele, wai o ke koko i loaʻa nā antibodies no kahi maʻi, e like me ka FDA. A inā ua hala ʻoe i ka papa biology papa 7, ʻo nā antibodies nā protein i hana ʻia e hakakā i nā maʻi maʻi ma hope o ka loaʻa ʻana o kēlā maʻi.

No laila, ʻo ka plasma convalescent he plasma wale nō ia mai ka mea i hoʻōla ʻia mai kahi maʻi - ma kēia hihia, COVID-19, wahi a Brenda Grossman, MD, ka luna lapaʻau o Transfusion Medicine ma Barnes-Jewish Hospital, a me kahi kaukaʻi ma Washington University School of Laau lapaau ma St. "Ua hoʻohana ʻia nā plasma convalescent i ka wā ma mua, me nā pae like ʻole o ka maikaʻi, no nā maʻi maʻi maʻi, me ka Spanish Flu, SARS, MERS, a me Ebola," wahi a Kauka Grossman.

I kēia manawa, eia kahi e komo ai ka "therapy": Ke loaʻa ka plasma mai kahi kanaka i hoʻōla ʻia, ua hoʻololi ʻia i loko o kahi maʻi maʻi o kēia manawa (a pinepine pinepine) i hiki ai i nā antibodies ke manaʻolana i ka "neutralize i ka maʻi a hiki ke hoʻonui i ka hoʻomaʻemaʻe o ka maʻi. mai ke kino," wahi a Emily Stoneman, MD, he loea maʻi maʻi maʻi ma ke Kulanui o Michigan ma Ann Arbor. I nā huaʻōlelo ʻē aʻe, hoʻohana ʻia "e hoʻoikaika i ka pale ʻana o ka mea maʻi a me ka manaʻolana e hōʻemi i ka hopena o ka maʻi."

Akā, e like me ka nui o ke ola (ugh, dating), ʻo ka manawa ka mea āpau. "ʻO ka maʻamau he ʻelua pule no ka poʻe i loaʻa i ka COVID-19 e hana i kēia mau antibodies ma o lākou iho," wahi a Dr. Stoneman. nā mea maʻi mai ka lilo ʻana i ka maʻi koʻikoʻi, "No laila, ʻoiai ʻoi aku ka nui o ka noiʻi ʻana e ʻike i ka pono o ka convalescent plasma therapy, ʻo ke kumu o kēia manawa ʻo ka loaʻa ʻana o ka mea maʻi i ka lāʻau lapaʻau, ʻoi aku ka nui o ka ʻike ʻana i nā hopena maikaʻi. (E pili pū ana: Pehea e hana ai me ka hopohopo olakino i ka wā o COVID-19, a ma waho aʻe)

ʻO wai ka mea hiki ke hāʻawi i ka plasma Convalescent no COVID-19?

Helu helu ʻekahi: ua loaʻa iā ʻoe ka coronavirus a loaʻa iā ʻoe ka hōʻike e hōʻoia ai.

"Hiki i ka poʻe ke hāʻawi i ka plasma inā loaʻa iā lākou kahi maʻi COVID-19 me nā palapala noiʻi (a i ʻole nasopharyngeal [nasal] swab a i ʻole ka hoʻāʻo antibody maikaʻi), ua ola hou, a he asymptomatic no ka liʻiliʻi ʻelua pule," wahi a Hyunah Yoon, MD, loea maʻi maʻi maʻi ma Albert Einstein College of Medicine. (E heluhelu pū hoʻi: He aha ka manaʻo o ka hoʻāʻo anti-body maikaʻi?)

ʻAʻole i loaʻa kahi maʻi i hoʻopaʻa ʻia akā hilinaʻi ua ʻike ʻoe i nā hōʻailona coronavirus? Nūhou maikaʻi: Hiki iā ʻoe ke hoʻonohonoho i kahi hoʻāʻo antibody ma kāu Keʻa ʻAmelika ʻAmelika a, inā maikaʻi nā hopena no nā antibodies, e hoʻomau e like me - ʻo ia hoʻi, ʻoiai ʻoe e hoʻokō i nā koi hāʻawi ʻē aʻe, e like me ka hōʻailona ʻole. no 14 mau lā ma mua o ka hāʻawi ʻana. ʻOiai ʻelua pule me ka ʻole o nā hōʻailona e ʻōlelo ʻia e ka FDA, hiki i kekahi mau halemai a me nā hui ke koi aku i nā mea hāʻawi i ka hōʻailona ʻole no nā lā 28, wahi a Kauka Grossman

Ma waho aʻe o kēlā, koi pū ka American Red Cross i nā mea hāʻawi plasma convalescent ma kahi o 17 mau makahiki, kaupaona 110 lbs, a hoʻokō i nā koi hāʻawi koko o ka hui. (E nānā i kēia alakaʻi no ka hāʻawi ʻana i ke koko e ʻike inā maikaʻi ʻoe e hele ma muli o kēlā mau koi.) He mea nui e hoʻomaopopo i ka wā maʻi ʻole, hiki iā ʻoe (a, TBH, pono) ke hāʻawi pū i ka plasma e hoʻohana ʻia no ʻO nā lāʻau lapaʻau ʻē aʻe no ka poʻe maʻi maʻi maʻi a me ke ahi a me nā mea pōʻino, e like me ka New York Blood Center.

He aha ka hāʻawi ʻana i ka plasma Convalescent?

I ka manawa āu i hoʻonohonoho ai i kahi kipa me kāu kikowaena hāʻawi kūloko, ua hiki i ka manawa e hoʻomākaukau. ʻO nā mea āpau e pili maoli ana, ʻo ka inu ʻana i ka nui o nā wai (ma ka liʻiliʻi 16oz.) A me ka ʻai ʻana i nā meaʻai protein-a me nā mea waiwai hao (ʻiʻo ʻula, iʻa, pīni, spinach) nā hola e hiki aku ana i kāu wā i koho ʻia ai e pale i ka make wai ʻole, ka mālamalama, a poniuniu, e like me ka American Red Cross.

Kamaʻāina ke kani? ʻO ia no ka mea like like ka plasma a me ka hāʻawi koko - koe wale no ka hana o ka hāʻawi manawaleʻa. Inā hāʻawi ʻoe i ke koko, ʻike ʻoe ua kahe ka wai mai kou lima a i loko o kahi ʻeke a ʻo ke koena ka mōʻaukala. ʻOi aku ka nui o ka hāʻawi ʻana i ka plasma, hewa, paʻakikī. I loko o kahi haʻawina plasma wale nō, huki ʻia ke koko mai hoʻokahi lima a hoʻouna ʻia ma o kahi mīkini ʻenehana kiʻekiʻe e hōʻiliʻili i ka plasma a laila hoʻihoʻi i nā ʻulaʻula a me nā platelet - me nā saline hydrating (aka saltwater) - hoʻi i kou kino. Pono kēia ma muli o ka wai he 92 pakeneka wai, e like me ka American Red Cross, a hoʻonui ka hana hāʻawi i kou makaʻu no ka make wai (ʻoi aku ma kēia ma lalo). ʻO ka hana hāʻawi manawaleʻa a pau ma kahi o hoʻokahi hola a me 15 mau minuke (ma kahi o 15 mau minuke wale nō ka lōʻihi ma mua o kahi hāʻawi koko wale nō), e like me ka American Red Cross.

E like me ka hāʻawi ʻana i ke koko, liʻiliʻi nā hopena ʻaoʻao o ka hāʻawi ʻana i ka plasma - ma hope o nā mea a pau, pono ʻoe i ke olakino maikaʻi e hiki ai i ka mua. ʻO ka ʻōlelo ʻia, e like me ka mea i ʻōlelo ʻia ma luna, hiki i ka make wai ke hiki. A no ia kumu, he mea nui e hoʻonui ʻoe i kāu inu wai i nā lā aʻe a e hoʻokele i ka haʻi kaumaha a me ka hoʻoikaika kino no ke koena o ka lā. A mai hopohopo no ka iho ʻana o kou kino i kekahi wai pono, e like me ka hiki (a ke hoʻololi) i ka nui o ke koko a i ʻole ka plasma ma loko o 48 mau hola.

No kāu pilikia COVID-19? ʻAʻole ia he mea hopohopo ma aneʻi. Hana ʻia ka hapa nui o nā kikowaena hāʻawi koko ma ke koho wale nō e hoʻāʻo e kākoʻo i nā hana hoʻomaʻamaʻa kaiapuni maikaʻi loa a ua hoʻokō i nā mea mālama hou e like me ka mea i kuhikuhi ʻia e nā Centers for Disease Control and Prevention (CDC).

Pololei ka ʻike ma kēia moʻolelo e like me ka manawa paʻi. Ke hoʻomau nei nā mea hou e pili ana i ka coronavirus COVID-19, ua loli paha kekahi mau ʻike a me nā manaʻo i kēia moʻolelo mai ka hoʻolaha mua ʻana. Paipai mākou iā ʻoe e nānā pinepine me nā kumuwaiwai e like me ka CDC, ka WHO, a me kāu keʻena olakino kūloko kūloko no ka ʻikepili a me nā ʻōlelo aʻoaʻo hou loa.

Nānā no