Mea Kākau: Janice Evans
Lā O Ka Hana: 3 Iulai 2021
HōʻAno Hou I Ka Lā: 18 Nowemapa 2024
Anonim
Dr. Ferrari on LBH589 and Bicalutamide in CRPC
Wikiō: Dr. Ferrari on LBH589 and Bicalutamide in CRPC

Anter

Hoʻohana ʻia ʻo Bicalutamide me kekahi lāʻau lapaʻau (gonadotropin-releasing hormone (GnRH) agonists; e like me leuprolide a i ʻole goserelin) e mālama ai i ka maʻi ʻaʻai prostate metastatic (maʻi ʻaʻai i hoʻomaka i ka prostate a ua hoʻolaha ʻia i nā ʻāpana ʻē aʻe o ke kino). Aia ʻo Bicalutamide i kahi papa o nā lāʻau i kapa ʻia he antiandrogens nonsteroidal. Hana ia ma ka pale ʻana i ka hopena o androgen (kahi kāne kāne hormone), e hoʻōki i ka ulu a hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Bicalutamide ma ke ʻano he papa e lawe ma ka waha. Lawe mau ʻia me a me ka ʻole o ka meaʻai i hoʻokahi lā i ka lā, i ke kakahiaka a i ʻole ke ahiahi. Lawe i ka bicalutamide ma kahi o ka manawa like i kēlā me kēia lā. Pono ʻoe e hoʻomaka i ka lawe ʻana i ka bicalutamide i ka lā like e hoʻomaka ai ʻoe e hoʻokomo i ka hōmona hoʻokuʻu hoʻokuʻu luteinizing. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka bicalutamide e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


Hiki i ka Bicalutamide me ka hormone hoʻokuʻu hoʻokuʻu luteinizing ke kōkua i ka hōʻoki ʻana i ka ulu a hoʻolaha ʻana o nā hunaola maʻi ʻaʻai akā ʻaʻole ia e hōʻola i ka maʻi ʻaʻai prostate. E hoʻomau i ka lawe i nā bicalutamide ʻelua a me ka hormonone hoʻokuʻu hoʻokuʻu luteinizing ʻoiai inā ʻoe e ʻoi aku ka maikaʻi. Mai hōʻoki i ka lawe ʻana i kēia mau lāʻau me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka bicalutamide,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka bicalutamide, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa bicalutamide. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: alprazolam (Xanax); anticoagulants ('blood thinners') e like me warfarin (Coumadin); aripiprazole (Abilify); buspirone (Buspar); nā poloka kalipuna e like me amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), nifedipine (Adalat, Procardia), nisoldipine (Sular), a me verapamil (Calan, Covera, Isoptin, Verelan); chlorpheniramine; nā lāʻau hoʻohaʻahaʻa kolesterol (statins) e like me atorvastatin (Lipitor), lovastatin (Mevacor), a me simvastatin (Zocor); clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); diazepam (Valium); erythromycin (E.E.S., E-Mycin, Erythrocin); Nā mea hoʻopalekana protease HIV e like me indinavir (Crixivan), ritonavir (Norvir), a me saquinavir (Invirase, Fortovase); methadone (Dolophine); midazolam (Versed); pimozide (Orap); quinidine (Quinidex, Quinaglute); quinine; sildenafil (Viagra); tacrolimus (Prograf); tamoxifen (Nolvadex); telithromycin (Ketek); trazodone (Desyrel); triazolam (Halcion); a me vincristine (Vincasar). Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka bicalutamide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate.
  • pono ʻoe e ʻike ʻo ka bicalutamide wale nō ka hoʻohana i nā kāne. Inā lawe ʻia e nā wahine hāpai, hiki i ka bicalutamide ke hana i nā mea ʻē aʻe i loko o ka ʻōpū. ʻAʻole pono nā wahine hāpai a hāpai paha i ka bicalutamide. Inā lawe ʻoe i ka bicalutamide ʻoiai ʻoe e hāpai ana, e kāhea koke i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Bicalutamide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • ʻālohilohi wela a i ʻole ka paheʻe ʻana
  • iwi, kua, a i ʻole ʻeha pelvis
  • nāwaliwali o nā mākala
  • ʻehaʻeha a ʻeha pū paha
  • ʻeha poʻo
  • pokole o ka hanu
  • hoʻonui i ke kahe o ke koko
  • ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • ʻūhā
  • kōpaʻa
  • nausea
  • ka luaʻi
  • abdominal eha
  • pāhoehoe
  • ʻenekini
  • hoʻololi i ka paona (pohō a loaʻa paha)
  • nalo ʻai ʻole
  • ʻūpā
  • ʻeha, puhi ʻana, a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae paha
  • paʻakikī i ka hiamoe
  • manaʻo weliweli a makaʻu ʻole paha
  • hūwī
  • ka houʻu ʻana
  • hiki ʻole ke kiʻi a mālama i kahi kūkulu
  • pono e mimi pinepine i ka pō
  • mimi koko
  • ʻinoʻī paʻakikī a paʻakikī paha
  • pinepine a me ka wikiwiki e pono i ka mimi
  • pilikia i ka hemo ʻana i ka ʻai
  • nā umauma ʻeha a pehu paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • melemele o ka ʻili a me nā maka
  • ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
  • luhi loa
  • kahe koko ʻole ʻana a palapū paha
  • nele i ka ikaika
  • hoʻohuhū ʻōpū
  • nalo ʻai ʻole
  • nā ʻōuli like flu
  • ʻeha a ʻeha paha o ka ʻaoʻao
  • ʻeha ka umauma

Hoʻokumu paha ʻo Bicalutamide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka bicalutamide.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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Nānā Hou - 01/15/2018

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