Mea Kākau: Marcus Baldwin
Lā O Ka Hana: 15 Iune 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Statin Side Effects | Atorvastatin, Rosuvastatin, Simvastatin Side Effects & Why They Occur
Wikiō: Statin Side Effects | Atorvastatin, Rosuvastatin, Simvastatin Side Effects & Why They Occur

Anter

Hoʻohana ʻia ʻo Simvastatin me ka papaʻai, ka pohō kaumaha, a me ka hoʻoikaika kino e hoʻemi i ka makaʻu o ka puʻuwai a me ka hahau ʻana a hoʻoliʻiliʻi i ka manawa kūpono e pono ai ke kīʻaha puʻuwai i ka poʻe i loaʻa ka maʻi puʻuwai a i ʻole ka makaʻu i ka maʻi maʻi puʻuwai. Hoʻohana ʻia ʻo Simvastatin e hoʻoliʻiliʻi i ka nui o nā mea momona e like me ka lipoprotein haʻahaʻa (LDL) kolesterol ("'ʻino kolesterol") a me nā triglycerides i loko o ke koko a hoʻonui i ka nui o ka lipoprotein kiʻekiʻe (HDL) kolesterol (' 'maikaʻi ka cholesterol') i loko o ke koko. Hiki ke hoʻohana ʻia ʻo Simvastatin e hoʻoliʻiliʻi i ka nui o ka kolesterol a me nā mea momona ʻē aʻe i loko o ke koko i nā keiki a me nā ʻōpio 10 a 17 mau makahiki o ka makahiki i loaʻa iā he hyperooligemia heterozygous ʻohana (kahi ʻano hoʻoilina kahi hiki ʻole ke lawe ʻia ka cholesterol mai ke kino maʻamau).Aia ʻo Simvastatin i kahi papa o nā lāʻau i kapa ʻia ʻo HMG-CoA reductase (nā statins). Hana ia ma ka hoʻolohi ʻana i ka hana ʻana o ka kōkōkō i loko o ke kino e hōʻemi i ka nui o ka kolesterol e kūkulu ʻia ma nā paia o nā aʻa a ālai i ke kahe o ke koko i ka puʻuwai, lolo, a me nā ʻāpana ʻē aʻe o ke kino.


ʻO ka hōʻuluʻulu ʻana o ka cholesterol a me nā momona ma nā paia o kou aʻa (kahi hana i ʻike ʻia ʻo atherosclerosis) e hoʻemi ana i ke kahe o ke koko a, no laila, hāʻawi ka oxygen i kou puʻuwai, lolo, a me nā ʻāpana ʻē aʻe o kou kino ʻO ka hoʻohaʻahaʻa ʻana i ke kiʻekiʻe o kou koko a me nā momona me ka simvastatin i hōʻike ʻia e pale ai i nā maʻi puʻuwai, angina (ʻeha o ka umauma), nā hahau, a me nā hōʻeha puʻuwai.

Hele mai ʻo Simvastatin ma ke ʻano he papaha a me kahi hoʻomaha e lawe ai i ka waha. Lawe pinepine ʻia nā papa i hoʻokahi manawa i ka lā i ke ahiahi. Lawe pinepine ʻia ka hoʻomaha ʻana i hoʻokahi manawa i ka lā i ke ahiahi ma kahi ʻōpū nele. E lawe i ka simvastatin ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka simvastatin. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻoluliluli maikaʻi i ka hoʻomaha no 20 maukona ma mua o kēlā me kēia hoʻohana.

Inā ʻoe e lawe ana i ka hoʻokuʻu simvastatin, mai hoʻohana i kahi teaspoon o ka home e ana i kāu mahele lāʻau. ʻAʻole pololei nā ana ʻana o ka home no ka ana ʻana i nā teaspoon, a loaʻa paha iā ʻoe ka nui o ka lāʻau a i ʻole ʻaʻole lawa ka lāʻau inā ʻoe e ana i kāu lāʻau me kahi teaspoon o ka home Ma kahi o, e hoʻohana i kahi hāmeʻa ana pono e like me ka puna lāʻau a i ʻole me ke kani o ka waha. E noi i kāu kauka a kauka paha inā ʻoe e kōkua i ke kiʻi ʻana a i ʻole ka hoʻohana ʻana i kahi hāmeʻa ana.


E hoʻomaka paha kāu kauka iā ʻoe ma kahi lāʻau haʻahaʻa o simvastatin a hoʻonui iki i kāu lāʻau, ʻaʻole ʻoi aku i hoʻokahi manawa i kēlā me kēia 4 pule.

E hoʻomau i ka lawe ʻana i ka simvastatin ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka simvastatin me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka simvastatin,

  • e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka simvastatin, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka papa simvastatin a i ʻole ka hoʻomaha waha. E noi i kāu kauka a kauka paha no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā e lawe nei ʻoe i nā lāʻau antifungal e like me itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil) a me voriconazole (Vfend); clarithromycin (Biaxin, i Prevpac); nā lāʻau i loaʻa i ka cobicistat (Stribild); cyclosporine (Gengraf, Neoral, Sandimmune); danazol; erythromycin (E.E.S., E-Mycin, Erythrocin); gemfibrozil (Lopid); Nā mea hoʻopalekana protease HIV e like me atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (i Kaletra), nelfinavir (Viracept), ritonavir (Norvir, i Kaletra), saquinavir (Invirase), a tipranavir (Aptivus); nefazodone; telaprevir (Incivek); a me telithromycin (Ketek). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka simvastatin inā ʻoe e lawe i kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe E ʻike pono i kekahi o kēia mau mea: amiodarone (Cordarone, Pacerone); amlodipine (Norvasc, ma Caduet, ma Lotrel); anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven); colchisin (Colcrys); digoxin (Digitek, Lanoxicaps, Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac); dronedarone (Multaq); nā lāʻau hoʻohaʻahaʻa kolesterol e like me fenofibrate (Tricor), lomitapide (Juxtapid), a me ka niacin (acid nicotinic, Niacor, Niaspan); ranolazine (Ranexa); a me verapamil (Calan, Covera, Isoptin, Verelan). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. E launa pū paha nā lāʻau ʻē aʻe me simvastatin, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi ate. E kauoha aku kāu kauka i nā hoʻāʻo ʻana i ke koko e ʻike i ke ʻano o ka maikaʻi o ka hana a kou ake inā ʻaʻole ʻoe e manaʻo he maʻi ka ake kou. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka simvastatin inā loaʻa ʻoe i ka maʻi ate a i ʻole inā hōʻike ʻia nā hoʻokolohua ke ulu nei ʻoe i ka maʻi ate.
  • e haʻi i kāu kauka inā inu ʻoe i nā mea inu ʻona ʻelua a ʻoi paha i kēlā me kēia lā, inā he 65 kou mau makahiki a ʻoi paha, a inā he ʻĀsia ʻoe, keu hoʻi inā he Pake ʻoe. E haʻi aku i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi gland thyroid underactive, diabetes, ka hopu ʻana i ka ʻeha, ʻehaʻeha a nāwaliwali paha, kaomi koko haʻahaʻa, a i ʻole nā ​​maʻi puʻupaʻa.
  • e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole ʻoe e hāpai i ka wā o kāu mālama ʻana me simvastatin. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i ka simvastatin, e hoʻōki i ka lawe ʻana i ka simvastatin a kāhea koke aku i kāu kauka. Hiki iā Simvastatin ke hōʻeha i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i ka simvastatin.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka simvastatin. Inā hoʻokipa ʻia ʻoe ma ka haukapila ma muli o ka hōʻeha koʻikoʻi a maʻi paha, e haʻi i ke kauka nāna ʻoe e mālama iā ʻoe ke lawe nei ʻoe i ka simvastatin.
  • e noi i kāu kauka e pili ana i ka hoʻohana palekana o nā inu waiʻona ʻoiai ʻoe e lawe nei i ka simvastatin. Hiki i ka waiʻona ke hoʻonui i ka hopena o nā hopena ʻino.

ʻAi i kahi papaʻai momona momona, momona momona. E mālama pono i nā hana hoʻoikaika kino a me nā papa kuhikuhi papaʻai i hana ʻia e kāu kauka a i ʻole dietitian. Hiki iā ʻoe ke kipa aku i ka pūnaewele Cholesterol Education Program (NCEP) pūnaewele no ka ʻike pili i ka papaʻai ma http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.


Hōʻalo i ka inu ʻana i ka wai wai mālamo i ka lawe ʻana i ka simvastatin

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i ka papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu ʻo Simvastatin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • kōpaʻa
  • ʻeha ka ʻōpū
  • nausea
  • ʻeha poʻo
  • poho poʻomanaʻo a poina paha
  • huikau
  • ʻili a ʻili ʻulaʻula paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka a i ʻole e loaʻa i ke kōkua olakino pilikia.

  • ʻeha ʻeha, palupalu, a nāwaliwali paha me ka ʻole o ke kuni a me ka ʻole o ka ikaika
  • mimi ʻulaʻula ʻeleʻele
  • hoʻemi urination
  • nele i ka ikaika, māluhiluhi, a nāwaliwali paha
  • nalo ʻai ʻole
  • ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū
  • melemele o ka ʻili a me nā maka
  • mimi kala ʻeleʻele
  • ke kunu a i ʻole ke anuanu
  • ʻōhinu
  • ʻōhū
  • hūwī
  • hives
  • ʻūlili
  • ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
  • pilikia i ka hanu ʻana a i ʻole ke ale ʻana
  • hulahula
  • ʻeha pū
  • ʻike i ka mālamalama

Hoʻokumu paha kēia lāʻau i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i nā papa i ka mahana o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i loko o ka lua. E mālama i ka hoʻomaha ma ke ana wela o ka lumi. Mai hoʻopili a hoʻomaʻalili i ka hoʻomaha. E hoʻohana pono i ka hoʻomaha ma waena o 30 mau lā o ka wehe ʻana o ka ʻōmole a hoʻolei i nā lāʻau i koe ma hope o 30 mau lā.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab i kāu mālama ʻana, keu hoʻi inā hoʻomohala ʻoe i nā ʻōuli o ka hōʻino o ke ake.

Ma mua o ka loaʻa ʻana o kahi hoʻokolohua hoʻokolohua, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua āu e lawe nei i ka simvastatin.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • ʻO Flolipid®
  • Zocor®
  • Juvisync® (i loaʻa iā Simvastatin, Sitagliptin)
  • Simcor® (me Niacin, Simvastatin)
  • ʻO Vytorin® (loaʻa iā Ezetimibe, Simvastatin)

ʻAʻole kēia huahana māka i ka mākeke hou. Hiki ke loaʻa nā koho ʻē aʻe.

Nānā Hou - 01/15/2020

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