ʻO Fedratinib

Anter

• Ma mua o ka lawe ʻana iā fedratinib,
• Hoʻokumu ʻo Fedratinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hiki i ka Fedratinib ke hana i ka encephalopathy (kahi maʻi koʻikoʻi a weliweli paha o ka ʻōnaehana nūhou), e like me ka encephalopathy ʻo Wernicke (kahi ʻano o ka encephalopathy i hoʻokumu ʻia e ka nele o ka thiamine [vitamini B1]). E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe kahi hemahema thiamine. Inā ʻoe e ʻike i kekahi o nā ʻōuli aʻe, e hoʻōki i ka lawe ʻana iā fedratinib a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino pōpilikia: ka paʻakikī e neʻe a mālama paha i kāu kaulike, nāwaliwali o nā wāwae a i ʻole nā ​​lima e hoʻomau i ka maikaʻi, huikau, hiamoe, paʻakikī i ka hoʻomaopopo ʻana a i ʻole ka ʻōlelo ʻana. ka nalowale o ka hoʻomanaʻo, nā pilikia o ka hihiʻo (me ka ʻike lua ʻana a me nā neʻe maka ʻole ʻana), a i ʻole nā ​​loli i ke ʻano.

Kau kauka paha i kau lāʻau e hōʻemi i ka hopena o nā hopena ʻē aʻe i loaʻa iā ʻoe mai ka lawe ʻana iā fedratinib. E haʻi koke aku i kāu kauka inā loaʻa ʻoe i ka nausea, ka luaʻi, ka palahī, a i ʻole ka pohō kaumaha e maikaʻi ʻole me ka lāʻau.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua e nānā i ka pane o kou kino iā fedratinib.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka ʻikepili ʻike hoʻomanawanui o ka mea hana (Ke Alakaʻi Medication) ke hoʻomaka ʻoe i ka lāʻau me fedratinib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu.Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Fedratinib e mālama i nā mākua me kekahi ʻano o ka myelofibrosis (MF; kahi maʻi ʻaʻai o ka iwi iwi kahi e kuapo ʻia ka iwi iwi e ka ʻili maka a hoʻoliʻiliʻi ka hana ʻana o ke koko). Aia ʻo Fedratinib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki a hoʻolohi paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Fedratinib ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā, me ka ʻai ʻole. Lawe iā fedratinib me kahi papaʻaina momona kiʻekiʻe e kōkua i ka hōʻemi i ka nausea a me ka luaʻi. Lawe iā fedratinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe iā fedratinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E kauoha kāu kauka i nā hoʻokolohua koko ma mua a i kāu wā e ʻike ai pehea ʻoe e hoʻopili ʻia ai e kēia lāʻau. Hiki i kāu kauka ke hoʻonui a hōʻemi paha i kāu lāʻau o fedratinib i kou wā e mālama ai, a i ʻole e haʻi aku iā ʻoe e haʻalele i ka lawe ʻana iā fedratinib no kahi manawa a mau loa paha. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe, nā hopena hōʻike lab, a inā ʻike ʻoe i nā hopena ʻaoʻao. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā fedratinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka fedratinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka capsrat fedratinib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hōʻike pono i kekahi o kēia mau mea: clarithromycin (Biaxin, ma PrevPac), diltiazem (Cardizem, Dilacor, Tiazac, a me nā mea ʻē aʻe), erythromycin (EES, E-mycin, Erythrocin), idelalisib (Zydelig), indinavir (Crixivan), itraconaz (Sporanox), ketoconazole (Nizoral), metoprolol (Lopressor, Toprol XL, ma Dutoprol, a me nā mea ʻē aʻe), midazolam (Versed), nefazodone, nelfinavir (Viracept), omeprazole (Prilosec, i Zegerid), ribociclib (Kisqali, Kisqali, i Femera ), ritonavir (Norvir), ruxolitinib (Jakafi), a me saquinavir (Invirase). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Pili pū paha nā lāʻau ʻē aʻe he nui me fedratinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate a me nā puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā hāpai ʻoe i ka lawe ʻana iā fedratinib, e kāhea i kāu kauka.
• mai hānai i ka wā o kāu mālama ʻana me fedratinib a no ka liʻiliʻi o 1 mau mahina ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe nei ʻoe iā fedratinib.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu ʻo Fedratinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• kōpaʻa
• luhi
• ʻūpē mākala
• ʻeha ka lima, ka wāwae, a ʻeha ka iwi
• ʻeha poʻo
• loaʻa kaupaona
• ʻūpā

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• kahe koko ʻole ʻana a palapū paha
• ke kuni, ke anu, ka ʻū, ka ʻeha a pinepine paha i ka urination, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• nausea, māluhiluhi nui loa, ʻeha a kolo paha ʻole, nele i ka ikaika, nalowale o ka makemake, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, melemele o ka ʻili a me nā maka, a me nā hōʻailona like flu.
• ka pōkole o ka hanu, ka wikiwiki o ka puʻuwai, ka ʻeha o ke poʻo, ka luhi, ka ʻili ʻulaʻula, huikau, a me ka luhi

Hoʻokumu ʻo Fedratinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Inrebic^®