Siponimod

Anter

• Ma mua o ka lawe ʻana i ka siponimod,
• Hoʻokumu paha ʻo Siponimod i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hoʻohana ʻia ʻo Siponimod e pale ai i nā ʻāpana o nā hōʻailona a hoʻolohi i ka hōʻino ʻana o ke kīnā ʻole i nā mākua me nā ʻano remitting remapsing (papa o ka maʻi kahi e piʻi ai nā ʻōuli mai kēlā me kēia manawa) o nā sclerosis he nui (MS; kahi maʻi kahi e holo pono ʻole ai nā ʻalalā. a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka coordination o nā mākala, a me nā pilikia me ka hihi, kamaʻilio, a me ka mālama ʻana i ka maʻi ʻaʻa. Aia ʻo Siponimod i loko o ka papa o nā lāʻau i kapa ʻia nā modulator receptor sp-spososine l-phosphate. Hana ia ma ka hoʻemi ʻana i ka hana o nā hunaola ʻino e hiki ai ke hōʻino i nā nerve.

Hele mai ʻo Siponimod ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka ʻai ʻole. Lawe iā siponimod ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka siponimod. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o siponimod a hoʻonui iki i kāu lāʻau no nā lā 4 a 5 paha i hala.

Hiki paha iā Siponimod ke hoʻolohi i ka puʻuwai puʻuwai, keu hoʻi i nā hola 6 mua ma hope o kou lawe ʻana i kāu kau ma mua. E loaʻa iā ʻoe kahi electrocardiogram (ECG; hōʻike e hoʻopaʻa i ka hana uila o ka puʻuwai) ma mua o kou lawe ʻana i kāu lāʻau mua a me 6 mau hola ma hope o kou lawe ʻana i ka lāʻau. E lawe ʻoe i kāu lāʻau mua o siponimod ma ke keʻena o kāu kauka a i ʻole kahi wahi olakino ʻē aʻe. Pono ʻoe e noho ma ke keʻena lapaʻau no 6 mau hola ma hope o kou lawe ʻana i ka lāʻau i hiki ke nānā ʻia. Pono ʻoe e noho ma ke keʻena olakino no ka lōʻihi ma mua o 6 mau hola a i ʻole ka pō inā loaʻa iā ʻoe kekahi mau ʻano a i ʻole lawe i kekahi mau lāʻau e hoʻonui i ka makaʻu e lohi ai kou puʻuwai a i ʻole inā lohi kou puʻuwai ma mua o ka mea i manaʻo ʻia a hoʻomau i ka lohi ma hope o ka 6 mua. mau hola. Pono paha ʻoe e noho ma kahi keʻena olakino ma kahi o 6 mau hola ma hope o kou lawe ʻana i kāu hopena ʻelua inā lohi nui kou puʻuwai ke lawe ʻoe i kāu kau mua. E haʻi i kāu kauka inā ʻike ʻoe i ka lōlō, ka luhi, ka ʻeha o ka umauma, a i ʻole ke kuʻi puʻuwai a i ʻole wā maʻamau i kēlā me kēia manawa i kāu wā e lapaʻau ai.

Hiki paha iā Siponimod ke kōkua i ka kaohi ʻana i nā sclerosis he nui akā ʻaʻole ia e hoʻōla iā ia. Mai hooki i ka lawe ʻana i ka siponimod me ka walaʻau ʻole ʻana me kāu kauka. Inā ʻaʻole ʻoe e lawe i ka siponimod no 1 lā a ʻoi aku paha i ka manawa o 4 a 5 mau lā o ka mālama ʻana a i ʻole no 4 mau lā a ʻoi aku paha ka lōʻihi ma hope o ka pule mua o ka hoʻomaʻamaʻa ʻana, e kamaʻilio me kāu kauka ma mua o kou hoʻomaka ʻana e lawe hou. Hiki paha iā ʻoe ke ʻike i ka puʻuwai lohi ke hoʻomaka ʻoe e lawe hou i ka siponimod, no laila pono ʻoe e hoʻomaka hou i ka lāʻau ma kahi lāʻau ma lalo o ke keʻena o kāu kauka a hoʻonui iki i ka lāʻau ma mua o 4 a 5 mau lā.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me siponimod a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka siponimod,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka siponimod i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka siponimod papa. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: alemtuzumab (Campath, Lemtrada); amiodarone (Nexterone, Pacerone); beta-blockers e like me atenolol (Tenormin, ma Tenoretic), carteolol, labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, ma Dutoprol, ma Lopressor HCT), nadolol (Corgard, ma Corzide), nebivolol (Bystolic, ma Byvalson ), propranolol (Inderal LA, Innopran XL), a me timolol; carbamazepine (Carbatrol, Equetro, Tegretol, a me nā mea ʻē aʻe); digoxin (Lanoxin); diltiazem (Cardizem, Cartia, Tiazac, nā mea ʻē aʻe); efavirenz (Sustiva, i Atripla, i Symfi); fluconazole (Diflucan); ivabradine (Corlanor); modafinil (Provigil); procainamide; quinidine (i Nuedexta); rifampin (Rifadin, Rimactane, ma Rifamate, nā mea ʻē aʻe); sotalol (Betapace, Sorine, Sotylize); a me ka verapamil (Calan, Verelan, ma Tarka). E haʻi aku iā ʻoe i ke kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe, a i ʻole inā ua lawe ʻoe iā lākou i ka wā ma mua: ʻo corticosteroids e like me dexamethasone, methylprednisolone (Medrol), a me prednisone (Rayos); nā lāʻau no ka maʻi ʻaʻai; a me nā lāʻau e hoʻonāwaliwali ai ʻole kaohi ʻana i ka ʻōnaehana pale e like me glatiramer acetate (Copaxone, Glatopa) a me interferon beta (Betaseron, Extavia, Plegridy). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me siponimod, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole kekahi o kēia mau ʻano i loko o nā mahina ʻeono i hala iho nei: ka puʻuwai puʻuwai, angina (ʻeha o ka umauma), hahau a i ʻole hahau iki ʻana, a i ʻole nā ​​puʻuwai puʻuwai. E haʻi pū aku i kāu kauka inā loaʻa iā ʻoe kahi lehelehe puʻuwai ʻole. E haʻi paha kāu kauka iā ʻoe mai lawe i ka siponimod.
• e haʻi i kāu kauka inā ua maule ʻoe, ua ʻeha ka puʻuwai, hahau, a i ʻole ka maʻi liʻiliʻi. inā he kuni kou a i ʻole nā ​​hōʻailona ʻino ʻē aʻe a i ʻole inā loaʻa ʻoe i kahi maʻi e hele a hele paha a i ʻole hele aku paha. a inā ua loaʻa iāʻoe a iʻole i loaʻa iāʻoe ka maʻi diabetes; papahō moe (ke ʻano e hoʻomaha iki ai i ka hanu ʻana i nā manawa he nui i ka pō) a i ʻole nā ​​pilikia hanu ʻē aʻe; ke koko kiʻekiʻe; uveitis (pehu o ka maka) a i ʻole nā ​​pilikia maka ʻē aʻe; he puʻuwai puʻuwai maʻi ʻaʻai o ka ʻili, a i ʻole ka maʻi puʻuwai a i ʻole ate. E haʻi aku i kāu kauka inā loaʻa iā ʻoe kahi lāʻau lapaʻau.
• e haʻi i kāu kauka inā hāpai ʻoe a hoʻolālā paha e hāpai, a i ʻole e hānai umauma ʻana. Pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a ma ka liʻiliʻi he 10 mau lā ma hope o kāu hopena hope loa. Inā hāpai ʻoe i ka lawe ʻana i ka siponimod a i ʻole ma waena o 10 mau lā ma hope o kāu hopena hope loa, e kāhea i kāu kauka.
• ʻaʻohe o nā lāʻau āpau no 1 hebedoma ma mua o kou hoʻomaka ʻana i kāu lapaʻau me siponimod, i kou wā e hoʻomaʻamaʻa ai, a i ʻole no 1 mau mahina ma hope o kāu hopena hope loa me ke kamaʻilio ʻole ʻana me kāu kauka. E kamaʻilio me kāu kauka e pili ana i nā lāʻau āpau āu e pono ai e loaʻa ma mua o ka hoʻomaka ʻana o kāu lapaʻau me ka siponimod.
• e haʻi i kāu kauka inā ʻaʻole i loaʻa i ka pox moa a ʻaʻole i loaʻa iā ʻoe ka lāʻau lapaʻau ʻo ka moa. Kauoha paha kāu kauka i kahi hoʻokolohua koko e ʻike inā ua ʻike ʻia ʻoe i ka moa moa. Pono paha ʻoe e loaʻa i ka lāʻau ākea pox moa a laila kali i 1 mahina ma mua o ka hoʻomaka ʻana i kāu lapaʻau me siponimod.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a kāhea i kāu kauka ma mua o kou lawe ʻana i ka lāʻau aʻe. Pono ʻoe e kiaʻi ʻia i kou hoʻomaka hou ʻana i kāu lāʻau i kahi mahele haʻahaʻa a me ka hoʻonui ʻia ʻana o ka lāʻau ma luna o 4 a 5 mau lā. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Siponimod i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nāwaliwali
• ʻeha ma nā lima, nā wāwae, nā lima a i ʻole nā ​​wāwae
• pāhoehoe
• ʻeha poʻo

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• ʻūlū puʻuwai
• ʻeha ka ʻāʻī, ʻehaʻeha o ke kino, ke kuni, ka haʻalulu, ka ʻūhā, a me nā hōʻailona ʻē aʻe o ka maʻi a i ka wā o ka mālama ʻana a hiki i ka 1 mahina ma hope o kāu lapaʻau.
• ʻeha poʻo, ʻāʻī ʻoʻoleʻa, kuni, ʻike i ka mālamalama, nausea, a huikau paha i ka wā o ka mālama ʻana a hiki i ka 1 mahina ma hope o kāu lapaʻau.
• ʻehaʻeha kūpikipiki nui, huikau, hoʻololi i ka hihiʻo, a i ʻole ka hopu ʻana
• blurriness, aka, a i ʻole kahi makapō i waenakonu o kāu ʻike; ʻike i ka mālamalama; kala ʻokoʻa i kāu hihiʻo a i ʻole nā ​​pilikia ʻike
• nāwaliwali ma kekahi ʻaoʻao o ke kino a i ʻole nā ​​clumsiness o nā lima a mau wāwae paha e ʻino i ka holo ʻana o ka manawa. nā hoʻololi i kou noʻonoʻo, hoʻomanaʻo, a kaulike paha; huikau a ʻano pilikino paha; aiʻole ka nalowale o ka ikaika
• pōkole hou o ka hanu
• nausea, luaʻi, nalo o ka makemake ʻole, ʻeha o ka ʻōpū, melemele o ka ʻili a me nā maka, a i ʻole ka mimi ʻeleʻele

Hiki i ka Siponimod ke hoʻonui i ka makaʻu o ka ulu ʻana i ka maʻi ʻaʻai ʻili. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hiki ke piʻi aʻe kahi mahele o nā hōʻailona MS a me ka hōʻino ʻana o ke kīnā ma hope o kou hooki ʻana i ka lawe ʻana i ka siponimod. E haʻi i kāu kauka inā hōʻeha kāu mau hōʻailona MS ma hope o ke kū ʻana o ka siponimod.

Hoʻokumu paha ʻo Siponimod i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama i nā ipu i wehe ʻole ʻia o kēia lāʻau i loko o ka pahu hau. Hiki ke mālama ʻia nā ʻeke a hāmama i ka wela o ka lumi a ma kahi mamao aku o ka wela a me ka momona (ʻaʻole i loko o ka lua.) No kekahi manawa. Hiki ke mālama ʻia nā ʻūhū blister hāmama i ka mahana o ka lumi a hiki i 1 pule ma hope o ka hoʻohana mua. Hiki ke mālama ʻia nā ʻōmole wehe i ke ana wela o ka lumi a hiki i 1 mahina ma hope o ka hoʻohana mua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• lohi a kuʻi ʻole paha ka puʻuwai puʻuwai

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua hoʻokolohua, nā hoʻāʻo ʻana o ka maka, a e nānā i kou kahe koko ma mua a i kou wā e hoʻomaʻamaʻa ai e palekana inā ʻoe e hoʻomaka i ka lawe ʻana a hoʻomau paha i ka lawe ʻana i ka siponimod.

Ma mua o ka hoʻāʻo ʻana i kahi lumi hoʻokolohua, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua e lawe nei ʻoe i ka siponimod.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Mayzent^®