Mea Kākau: Janice Evans
Lā O Ka Hana: 1 Iulai 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Ranolazine - Side Effects, Mechanism of Action, and Indications
Wikiō: Ranolazine - Side Effects, Mechanism of Action, and Indications

Anter

Hoʻohana hoʻokahi ʻia ʻo Ranolazine a i ʻole me nā lāʻau ʻē aʻe e mālama i ka angina mau (ʻeha mau ka umauma a i ʻole kaomi e ʻike ʻia ke loaʻa ʻole ka oxygen i ka puʻuwai). Aia ʻo Ranolazine i kahi papa o nā lāʻau i kapa ʻia he anti-anginals. ʻAʻole ʻike ʻia ke ala kikoʻī e hana ai ʻo ranolazine i kēia manawa.

Hele mai ʻo Ranolazine ma ke ʻano he papa hoʻolōʻihi (hana lōʻihi) e lawe ma ka waha. Lawe pinepine ʻia me a me ka ʻole o ka meaʻai i ʻelua mau lā. Lawe iā ranolazine ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe iā ranolazine e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai uhaʻi, a nau i ka ʻai.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o ka ranolazine a hoʻonui iki i kāu lāʻau.

Mai lawe iā ranolazine e mālama i ka hoʻouka kaua ʻana o angina. E haʻi aku kāu kauka iā ʻoe i kāu mea e hana ai inā ʻike ʻoe i ka hoʻouka kaua ʻana o angina. E ʻike pono i ka maopopo ʻana iā ʻoe i kēia mau ʻaoʻao.


Hiki paha iā Ranolazine ke kōkua i ke kaohi i kou ʻano akā ʻaʻole e hoʻōla iā ia. E hoʻomau i ka lawe ʻana i ka ranolazine inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka ranolazine me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka ranolazine,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka ranolazine, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ranolazine mau papa hoʻokuʻu hoʻonui ʻia. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe: antifungals e like me itraconazole (Onmel, Sporanox) a me ketoconazole (Nizoral); clarithromycin (Biaxin, i Prevpac); nā lāʻau e mālama ai i ka maʻi pale maʻi (HIV) a i ʻole ka maʻi maʻi loaʻa (AIDS) e like me indinavir (Crixivan), lopinavir a me ritonavir (Kaletra); nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra, ma Viekira Pak, kekahi), a me saquinavir (Invirase); nefazodone; nā lāʻau no ka hopu ʻana e like me ka carbamazepine (Carbatrol, Equetro, Tegretol, a me nā mea ʻē aʻe), phenobarbital, a me phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); a me rifapentin (Priftin). E haʻi pū aku i kāu kauka inā lawe ʻoe i ka wort a St. E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka ranolazine inā ʻoe e lawe i hoʻokahi aʻoi aku paha o kēia mau lāʻau a i ʻole nā ​​huahana lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻike pono i kekahi o kēia mau mea: amiodarone (Cordarone, Nexterone, Pacerone); nā antidepressants e like me amitriptyline, clomipramine (Anafranil), a me desipramine (Norpramin); a me ka imipramine (Tofranil); nā lāʻau e mālama ai i ke kolamu kiʻekiʻe e like me atorvastatin (Lipitor, ma Caduet), lovastatin (Altoprev, ma Advicor), a me simvastatin (Zocor, i Simcor, i Vytorin); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac, nā mea ʻē aʻe); dofetilide; (Tikosyn); erythromycin (E.E.S., Erythrocin, PCE); fluconazole (Diflucan); nā lāʻau no ka maʻi noʻonoʻo e like me haloperidol (Haldol), risperidone (Risperdal), thioridazine, a me ziprasidone (Geodon); metformin (Fortamet, Glumetza, i Glucovance, nā mea ʻē aʻe); quinidine (i Nuedexta); sirolimus (Rapamune); sotalol (Betapace, Sorine); tacrolimus (Astagraf, Envarsus XR, Prograf); and verapamil (Calan, Covera, Verelan, kekahi). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ranolazine, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa a i ʻole ka papa inoa ma luna.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate. E haʻi paha kāu kauka iā ʻoe ʻaʻole ʻoe e lawe i ka ranolazine.
  • e haʻi i kāu kauka inā ʻoe a i ʻole kekahi o kou ʻohana a i ʻole loaʻa i kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hoʻonāukiuki ai ʻole ka puʻuwai puʻuwai ʻole a i ʻole ka wikiwiki o ka naʻau. E haʻi pū aku i kāu kauka inā loaʻa iā ʻoe a i ʻole he electrocardiogram maʻamau (ECG: kahi hōʻike e hoʻopaʻa i ka hana uila o ka puʻuwai), nā pae haʻahaʻa o ka potassium i loko o ke koko, a i ʻole nā ​​maʻi kidney.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana iā ranolazine, e kāhea i kāu kauka.
  • pono ʻoe e ʻike ʻo ka ranolazine paha e hoʻoluhi ai i ka uila. Mai kalaiwa i ke kaʻa, hana i nā mīkini, a i ʻole e komo i nā hana e koi ai i ka noʻonoʻo a me ka hoʻohuihui ʻana a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.

Mai inu i ka wai huaʻiku a ʻai ʻole i nā huahana grapefruit ʻoiai ke lawe nei i kēia lāʻau.


E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Ranolazine i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nausea
  • kōpaʻa
  • ʻeha poʻo
  • ʻūpā

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • wikiwiki, kuʻi, a i ʻole kuʻi puʻuwai puʻuwai
  • paʻakikī i ka hanu ʻana
  • maule ana

Hoʻokumu paha ʻo Ranolazine i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau ke lawe nei ʻoe i kēia lāʻau.

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.


He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

  • nausea
  • ka luaʻi
  • ʻūpā
  • huikau
  • hihio pālua
  • ʻeha, puhi ʻana, numbness a i ʻole ʻūlū ʻana i kekahi ʻāpana o ke kino
  • maule ana
  • luliluli ʻole ʻana i kahi ʻāpana o ke kino
  • paʻakikī e ʻōlelo
  • ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole

Mālama i nā manawa āpau me kāu kauka.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Ranexa®
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