Hōʻike koko ACTH

Ana ke ana o ka ACTH i ke kiʻekiʻe o ka hormone adrenocorticotropic (ACTH) i ke koko. ʻO ACTH kahi homone i hoʻokuʻu ʻia mai ka pituitary gland i ka lolo.

Pono kahi laʻana koko.

E noi paha kāu kauka iā ʻoe e hana i ka hoʻokolohua i kakahiaka nui. He mea nui kēia, no ka mea, ʻokoʻa ka pae o cortisol i ka lā holoʻokoʻa.

ʻ belelo ʻia paha ʻoe e haʻalele i ka lawe ʻana i nā lāʻau i hiki ke hoʻololi i nā hopena hōʻike. Hoʻopili kēia mau lāʻau i nā glucocorticoids e like me prednisone, hydrocortisone, a i ʻole dexamethasone. (Mai hōʻoki i kēia mau lāʻau inā ʻaʻole kuhikuhi ʻia e kāu mea hāʻawi.)

Ke hoʻokomo ʻia ke kui kele e huki i ke koko, manaʻo kekahi poʻe i ka ʻeha kaulike. ʻIke wale kekahi i kahi ʻōniʻu a i ʻole kui. Ma hope, loaʻa paha i kahi kūpikipiki a i ʻole ʻeha iki. Hele koke kēia.

ʻO ka hana nui o ka ACTH ka hoʻoponopono ʻana i ka glucocorticoid (steroid) hormone cortisol. Hoʻokuʻu ʻia ʻo Cortisol e ka adrenal gland. Hoʻoponopono ia i ke kaomi koko, ke kō kō, ka ʻōnaehana pale a me ka pane i ke koʻikoʻi.

Hiki i kēia hoʻāʻo ke kōkua i ka ʻike ʻana i nā kumu o kekahi mau pilikia hormone.

ʻO nā kumukūʻai maʻamau no kahi hāpana koko i lawe ʻia i kakahiaka nui ʻo 9 a 52 pg / mL (2 a 11 pmol / L).

Hiki ke loli iki nā pae waiwai maʻamau i waena o nā hale hana ʻokoʻa. Hoʻohana kekahi mau labs i nā ana like ʻole a i ʻole hoʻokolohua i nā hoʻohālikelike like ʻole. E kamaʻilio me kāu kauka e pili ana i ke ʻano o kāu mau hopena hōʻike kikoʻī.

E hōʻike paha kahi pae kiʻekiʻe ma mua o ka maʻamau o ACTH:

• ʻAʻole hana nā adrenal adrenal i ka nui o ka cortisol (maʻi Addison)
• ʻAʻole hana nā adrenal adrenal i nā hormoni (hyperplasia adrenal congenital)
• Hoʻokahi a ʻoi paha o nā gland endocrine overactive a i hana i kahi tumo (he nui endocrine neoplasia ʻano I)
• Ke hana nei ʻo Pituitary i ka nui o ka nui o ka ACTH (Cushing disease), ka mea maʻa mau ʻia e kahi tumo maʻi ʻole o ka pituitary gland.
• ʻAno liʻiliʻi o ka tumor (lung, thyroid, a pancreas) e hana nei i ka nui o ka ACTH (ectopic Cushing Syndrome)

Hōʻike kahi pae haʻahaʻa ma mua o ka maʻamau o ACTH:

• Ke kāohi nei nā lāʻau Glucocorticoid i nā hana ACTH (ʻoi loa)
• ʻAʻole hana ka pituitary gland i nā hormona, e like me ACTH (hypopituitarism)
• Tumor o ka adrenal gland e hoʻohua i ka nui o ka cortisol

ʻAʻohe pilikia iki i ka lawe ʻia ʻana o kou koko. ʻOkoʻa nā aʻa a me nā aʻa i ka nui mai kekahi kanaka a i kekahi ʻē aʻe a mai kekahi ʻaoʻao o ke kino i kekahi. ʻOi aku ka paʻakikī o ka lawe ʻana i ke koko mai kekahi poʻe ma mua o nā poʻe ʻē aʻe.

ʻO nā pilikia ʻē aʻe e pili ana i ke kau ʻana o ke koko he liʻiliʻi akā hiki ke hoʻopili ʻia:

• Kahe nui ke koko
• Pāleʻale a ʻoluʻolu paha
• Nā punctures he nui e ʻimi i nā uaua
• Hematoma (hōʻiliʻili koko ma lalo o ka ʻili)
• Maʻiʻaʻai (i iki kamepiula i kēlā me kēia manawa ka ʻili i haki)

Serum adrenocorticotropic hōmona; ʻAmona adrenalotorticotropic; ʻO ACTH koʻikoʻi koʻikoʻi loa

• Nānā Endocrine

Chernecky CC, Berger BJ. Adrenocorticotropic hormone (ACTH, corticotropin) - serum. I: Chernecky CC, Berger BJ, hua. Nā Hoʻokolohua Laboratory a me nā kaʻina hana Diagnostic. ʻElua huaʻōlelo St Louis, MO: Elsevier Saunders; 2013: 107.

Melmed S, Kleinberg D. Pituitary masses a me nā tumors. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 9.

ʻO Stewart PM, Newell-Kumukūʻai JDC. ʻO ka Cortex adrenal. I: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 15.